DPP6 (NM_001290252) Human Tagged ORF Clone

CAT#: RG239501

DPP6 (GFP-tagged) - Human dipeptidyl-peptidase 6 (DPP6), transcript variant 4

Specifications

Product Data

• Tag: TurboGFP
• Symbol: DPP6
• Synonyms: DPL1; DPPX; MRD33; VF2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG239501 representing NM_001290252.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGACCACAGCCAAGGAGCCAAGCGCTTCGGGGAAATCCGTGCAGCAGCAGGAACAGGAGCTGGTGGGG
  AGTAACCCTCCGCAGAGGAATTGGAAAGGAATAGCAATTGCACTGCTTGTCATTCTGGTCATCTGCTCC
  TTGATCGTCACCTCGGTCATACTTCTGACACCAGCGGAAGATAATAGTCTGTCTCAAAAGAAGAAGGTC
  ACTGTAGAAGATCTCTTCAGTGAAGACTTCAAAATTCATGACCCCGAGGCTAAGTGGATAAGTGATACA
  GAATTCATCTACAGAGAACAGAAAGGAACAGTGAGACTGTGGAATGTTGAAACAAATACTTCTACTGTC
  TTAATAGAAGGCAAAAAAATTGAATCATTAAGAGCCATCAGATATGAAATATCTCCAGATAGAGAGTAT
  GCACTTTTTTCATACAATGTGGAACCCATATTTATTTTTGAAAACAATATCTACTACTGTGCACATGTC
  GGGAAACAGGCCATCCGTGTGGTCTCCACTGGCAAGGAAGGTGTGATTTACAATGGCCTCAGTGACTGG
  CTGTATGAAGAGGAGATTTTGAAGACACACATCGCACACTGGTGGTCTCCGGATGGCACGAGACTCGCC
  TACGCCGCCATCAATGATTCCCGTGTCCCCATCATGGAGCTCCCAACTTACACCGGCTCCATCTACCCC
  ACCGTGAAGCCCTACCACTATCCCAAGGCTGGAAGTGAGAACCCCAGCATTTCCCTACACGTTATTGGC
  TTAAATGGACCCACCCATGATCTGGAGATGATGCCGCCTGATGATCCACGGATGAGGGAGTACTACATC
  ACCATGGTGAAGTGGGCCACCAGCACCAAGGTCGCCGTGACCTGGCTGAACCGGGCGCAGAACGTGTCC
  ATCCTCACCCTCTGCGACGCCACCACGGGGGTCTGCACGAAGAAACACGAGGATGAAAGTGAGGCCTGG
  CTCCACAGACAGAATGAAGAACCTGTGTTCTCCAAGGATGGCCGAAAGTTTTTCTTCATCAGAGCCATC
  CCCCAGGGAGGACGAGGGAAATTCTATCACATCACGGTGTCCTCGTCCCAGCCCAACAGCAGCAACGAC
  AACATCCAGTCCATCACCTCCGGGGACTGGGACGTGACCAAGATCCTAGCCTACGATGAGAAGGGGAAT
  AAGATCTACTTCCTGAGCACGGAGGACCTGCCTCGGAGACGACAACTCTACAGTGCCAACACGGTGGGC
  AACTTCAACAGGCAGTGCCTCTCCTGTGACCTGGTTGAGAACTGCACCTACTTCAGCGCTTCCTTCAGC
  CATAGCATGGACTTCTTCCTGCTCAAGTGCGAAGGTCCTGGTGTTCCTATGGTGACGGTGCACAACACA
  ACAGATAAGAAAAAAATGTTTGACCTAGAAACAAATGAACATGTCAAGAAGGCCATAAATGACCGACAG
  ATGCCTAAAGTGGAATACAGGGACATTGAGATTGATGATTACAACCTGCCCATGCAGATACTGAAGCCA
  GCAACCTTCACCGACACCACCCACTACCCTCTGCTCCTGGTGGTGGATGGCACCCCAGGCAGCCAGAGT
  GTGGCTGAGAAGTTCGAGGTGAGCTGGGAGACGGTGATGGTGAGCAGCCACGGCGCGGTGGTGGTAAAG
  TGTGACGGCCGTGGCAGCGGCTTCCAAGGGACCAAGCTCCTGCACGAAGTGAGGCGGCGGCTGGGCTTG
  CTGGAGGAGAAGGACCAGATGGAGGCCGTGCGGACGATGCTGAAGGAGCAGTACATTGACAGGACGCGC
  GTGGCCGTGTTTGGGAAGGATTACGGTGGCTACCTGAGCACCTACATCCTCCCAGCAAAGGGAGAAAAT
  CAAGGCCAGACATTCACCTGCGGCTCTGCTCTCTCTCCAATAACAGACTTCAAACTCTATGCCTCTGCG
  TTTTCCGAGAGGTACTTGGGCCTCCATGGACTTGACAACAGAGCATACGAGATGACCAAGGTAGCCCAT
  CGAGTCTCCGCGCTGGAAGAACAGCAGTTCCTGATCATTCATCCCACTGCCGATGAAAAAATTCATTTC
  CAGCACACAGCAGAACTCATTACACAACTAATTAGGGGAAAGGCTAATTACAGCTTACAGATTTACCCG
  GACGAAAGCCATTACTTTACCAGCTCCAGCCTCAAACAGCATCTGTACCGGTCCATCATCAACTTCTTC
  GTGGAATGCTTCAGGATCCAGGACAAACTGCTGACAGTCACAGCGAAAGAGGACGAGGAGGAGGAC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG239501
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAEDNSLSQKKKV
  TVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGKKIESLRAIRYEISPDREY
  ALFSYNVEPIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHWWSPDGTRLA
  YAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYI
  TMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVFSKDGRKFFFIRAI
  PQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVG
  NFNRQCLSCDLVENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQ
  MPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVK
  CDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYILPAKGEN
  QGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHF
  QHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINFFVECFRIQDKLLTVTAKEDEEED
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001290252
• ORF Size: 2274 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001290252.2
• RefSeq Size: 4370 bp
• RefSeq ORF: 2277 bp
• Locus ID: 1804
• Cytogenetics: 7q36.2
• Protein Families: Druggable Genome, Protease, Transmembrane
• MW: 86.8 kDa
• Gene Summary: 'This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]'