ADNP (NM_001282532) Human Tagged ORF Clone

CAT#: RG239968

ADNP (GFP-tagged) - Human activity-dependent neuroprotector homeobox (ADNP), transcript variant 4

Specifications

Product Data

• Tag: TurboGFP
• Symbol: ADNP
• Synonyms: ADNP1; HVDAS; MRD28
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG239968 representing NM_001282532.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGTTCCAACTTCCTGTCAACAATCTTGGCAGTTTAAGAAAAGCCCGGAAAACTGTGAAAAAAATACTT
  AGTGACATTGGGTTGGAATACTGTAAAGAACATATAGAAGATTTTAAACAATTTGAACCTAATGACTTT
  TATTTGAAAAACACTACATGGGAGGATGTAGGACTGTGGGACCCATCACTTACGAAAAACCAGGACTAT
  CGGACAAAACCTTTCTGCTGCAGCGCTTGTCCATGTTCCTCAAAATTCTTCTCTGCCTACAAAAGTCAT
  TTCCGCAATGTCCATAGTGAAGACTTTGAAAATAGGATTCTCCTTAATTGCCCCTACTGTACCTTCAAT
  GCAGACAAAAAGACTTTGGAAACACACATTAAAATATTTCATGCTCCGAACGCCAGCGCACCAAGTAGC
  AGCCTCAGCACTTTCAAAGATAAAAACAAAAATGATGGCCTTAAACCTAAGCAGGCTGACAGTGTAGAG
  CAAGCTGTTTATTACTGTAAGAAGTGCACTTACCGAGATCCTCTTTATGAAATAGTTAGGAAGCACATT
  TACAGGGAACATTTTCAGCATGTGGCAGCACCTTACATAGCAAAGGCAGGAGAAAAATCACTCAATGGG
  GCAGTCCCCTTAGGCTCGAATGCCCGAGAAGAGAGTAGTATTCACTGCAAACGATGCCTTTTCATGCCA
  AAGTCCTATGAAGCTTTGGTACAGCATGTCATCGAAGACCATGAACGTATAGGCTATCAGGTCACTGCC
  ATGATTGGGCACACAAATGTAGTGGTTCCCCGATCCAAACCCTTGATGCTAATTGCTCCCAAACCTCAA
  GACAAGAAGAGCATGGGACTCCCACCAAGGATCGGTTCCCTTGCTTCTGGAAATGTCCGGTCTTTACCA
  TCACAGCAGATGGTGAATCGACTCTCAATACCAAAGCCTAACTTAAATTCTACAGGAGTCAACATGATG
  TCCAGTGTTCATCTGCAGCAGAACAACTATGGAGTCAAATCTGTAGGCCAGGGTTACAGTGTTGGTCAG
  TCAATGAGACTGGGTCTAGGTGGCAACGCACCAGTTTCCATTCCTCAACAATCTCAGTCTGTAAAGCAG
  TTACTTCCAAGTGGAAACGGAAGGTCTTATGGGCTTGGGTCAGAGCAGAGGTCCCAGGCACCAGCAAGA
  TACTCCCTGCAGTCTGCTAATGCCTCTTCTCTCTCATCGGGCCAGTTAAAGTCTCCTTCCCTCTCTCAG
  TCACAGGCATCCAGAGTGTTAGGTCAGTCCAGTTCCAAACCTGCTGCAGCTGCCACAGGCCCTCCCCCA
  GGTAACACTTCCTCAACTCAAAAGTGGAAAATATGTACAATCTGTAATGAGCTTTTTCCTGAAAATGTC
  TATAGTGTGCACTTCGAAAAAGGACATAAAGCTGAGAAAGTCCCAGCAGTAGCCAACTACATTATGAAA
  ATACACAATTTTACTAGCAAATGCCTCTACTGTAATCGCTATTTACCCACAGATACTCTGCTCAACCAT
  ATGTTAATTCATGGTCTGTCTTGTCCATATTGCCGTTCAACTTTCAATGATGTGGAAAAGATGGCCGCA
  CACATGCGGATGGTTCACATTGATGAAGAGATGGGACCTAAAACAGATTCTACTTTGAGTTTTGATTTG
  ACATTGCAGCAGGGTAGTCACACTAACATCCATCTCCTGGTAACTACATACAATCTGAGGGATGCCCCA
  GCTGAATCTGTTGCTTACCATGCCCAAAATAATCCTCCAGTTCCTCCAAAGCCACAGCCAAAGGTTCAG
  GAAAAGGCAGATATCCCTGTAAAAAGTTCACCTCAAGCTGCAGTGCCCTATAAAAAAGATGTTGGGAAA
  ACCCTTTGTCCTCTTTGCTTTTCAATCCTAAAAGGACCCATATCTGATGCACTTGCACATCACTTACGA
  GAGAGGCACCAAGTTATTCAGACGGTTCATCCAGTTGAGAAAAAGCTCACCTACAAATGTATCCATTGC
  CTTGGTGTGTATACCAGCAACATGACCGCCTCAACTATCACTCTGCATCTAGTTCACTGCAGGGGCGTT
  GGAAAGACCCAAAATGGCCAGGATAAGACAAATGCACCCTCTCGGCTTAATCAGTCTCCAAGTCTGGCA
  CCTGTGAAGCGCACTTACGAGCAAATGGAATTTCCCTTACTGAAAAAACGAAAGTTAGATGATGATAGT
  GATTCACCCAGCTTCTTTGAAGAGAAGCCTGAAGAGCCTGTTGTTTTAGCTTTAGACCCCAAGGGTCAT
  GAAGATGATTCCTATGAAGCCAGGAAAAGCTTTCTAACAAAGTATTTCAACAAACAGCCCTATCCCACC
  AGGAGAGAAATTGAGAAGCTAGCAGCCAGTTTATGGTTATGGAAGAGTGACATCGCTTCCCATTTTAGT
  AACAAAAGGAAGAAGTGTGTCCGTGATTGTGAAAAGTACAAGCCTGGCGTGTTGCTGGGGTTTAACATG
  AAAGAATTAAATAAAGTCAAGCATGAGATGGATTTTGACGCTGAGTGGCTATTTGAAAATCATGATGAG
  AAGGATTCCAGAGTCAATGCTAGTAAGACTGCTGACAAAAAGCTCAACCTTGGGAAGGAAGATGACAGT
  TCCTCAGACAGTTTTGAAAATTTGGAAGAAGAATCCAATGAAAGTGGTAGCCCTTTTGACCCTGTTTTT
  GAAGTTGAACCTAAAATCTCTAACGATAACCCAGAGGAACATGTACTGAAGGTAATTCCTGAGGATGCT
  TCAGAATCTGAGGAGAAGCTAGACCAAAAAGAGGATGGTTCAAAATACGAAACTATTCATTTGACTGAG
  GAACCAACCAAACTAATGCACAATGCATCTGATAGTGAGGTTGACCAAGACGATGTTGTTGAGTGGAAA
  GACGGTGCTTCTCCATCTGAGAGTGGGCCTGGATCCCAACAAGTGTCAGACTTTGAGGACAATACCTGC
  GAAATGAAACCAGGAACCTGGTCTGACGAGTCTTCCCAAAGCGAAGATGCAAGGAGCAGTAAGCCAGCT
  GCCAAAAAAAAGGCTACCATGCAAGGTGACAGAGAGCAGTTGAAATGGAAGAATAGTTCCTATGGAAAA
  GTTGAAGGGTTTTGGTCTAAGGACCAGTCACAGTGGAAGAATGCATCTGAGAATGATGAGCGCTTATCT
  AACCCCCAGATTGAGTGGCAGAATAGCACAATTGACAGTGAGGATGGGGAACAGTTTGACAACATGACT
  GATGGAGTAGCTGAGCCCATGCATGGCAGCTTAGCCGGAGTTAAACTGAGCAGCCAACAGGCC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG239968
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDY
  RTKPFCCSACPCSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNASAPSS
  SLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYIAKAGEKSLNG
  AVPLGSNAREESSIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQ
  DKKSMGLPPRIGSLASGNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSSVHLQQNNYGVKSVGQGYSVGQ
  SMRLGLGGNAPVSIPQQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQ
  SQASRVLGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKGHKAEKVPAVANYIMK
  IHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDL
  TLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNPPVPPKPQPKVQEKADIPVKSSPQAAVPYKKDVGK
  TLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGV
  GKTQNGQDKTNAPSRLNQSPSLAPVKRTYEQMEFPLLKKRKLDDDSDSPSFFEEKPEEPVVLALDPKGH
  EDDSYEARKSFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNM
  KELNKVKHEMDFDAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVF
  EVEPKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWK
  DGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQLKWKNSSYGK
  VEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTDGVAEPMHGSLAGVKLSSQQA
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001282532
• ORF Size: 3306 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001282532.1, NP_001269461.1
• RefSeq Size: 6110 bp
• RefSeq ORF: 3309 bp
• Locus ID: 23394
• Cytogenetics: 20q13.13
• Protein Families: Transcription Factors
• MW: 123.4 kDa
• Gene Summary: Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]