Tp63 (NM_001127343) Rat Untagged Clone

CAT#: RN200160

Tp63 (untagged ORF) - Rat tumor protein p73-like (Tp73l), transcript variant 5, (10 ug)

Specifications

Product Data

• Type: Rat Untagged Clone
• Tag: Tag Free
• Symbol: Tp63
• Synonyms: Ket; P73l; Tp73l; Trp63
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >RN200160 representing NM_001127343
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTTGTACCTGGAAAGCAATGCCCAGACTCAATTTAGTGAGCCACAGTACACGAACCTGGGGCTCCTGA
  ACGGCATGGACCAGCAGATTCAGAACGGCTCCTCATCTACCAGCCCCTATAACACAGACCATGCACAGAA
  CAGCGTGACGGCACCCTCGCCCTATGCACAGCCCAGCTCAACCTTCGATGCCCTTTCTCCATCCCCTGCC
  ATTCCCTCCAACACAGATTACCCAGGCCCACACAGCTTCGATGTGTCCTTCCAGCAGTCAAGCACCGCCA
  AGTCAGCTACCTGGACGTATTCCACCGAACTGAAGAAACTCTACTGCCAGATTGCAAAGACCTGCCCCAT
  CCAGATCAAGGTGATGACCCCACCCCCACAGGGCGCCGTCATTCGTGCCATGCCTGTCTACAAGAAAGCC
  GAGCATGTCACCGAGGTTGTGAAACGATGTCCTAACCACGAGCTGAGCCGCGAGTTCAATGAGGGACAGA
  TTGCCCCTCCCAGTCATCTGATTCGAGTAGAAGGGAACAGCCATGCCCAGTATGTAGAAGATCCTATCAC
  AGGAAGGCAGAGCGTGCTGGTCCCTTATGAGCCACCACAGGTTGGCACTGAATTCACAACAGTCCTGTAC
  AATTTCATGTGCAACAGCAGCTGTGTCGGAGGAATGAACCGCCGTCCAATTTTAATCATCGTTACTCTGG
  AAACCAGAGATGGGCAAGTCCTGGGCCGACGTTGCTTTGAGGCCCGGATCTGCGCTTGCCCAGGAAGAGA
  CCGGAAGGCCGATGAAGACAGCATCAGAAAGCAGCAAGTATCAGACAGCGCAAAGAACGGCGATGGTACG
  AAGCGCCCTTTCCGTCAGAATACCCACGGAATCCAGATGACTTCCATCAAGAAACGGAGATCCCCAGATG
  ATGAGCTGCTGTACCTACCAGTGAGAGGCCGTGAGACTTATGAAATGCTGCTCAAGATCAAGGAGTCGCT
  CGAGCTCATGCAGTATCTCCCTCAGCACACGATCGAGACGTACAGGCAGCAGCAGCAGCAGCAGCACCAA
  CACCTACTTCAGAAACAGACCTCGATGCAGTCTCAGTCTTCATACGGTAACAGCTCACCACCTCTGAACA
  AAATGAACAGCATGAACAAGCTGCCGTCTGTGAGCCAGCTTATCAACCCACAGCAGCGCAACGCCCTGAC
  TCCCACCACCATGCCTGAGGGCATGGGAGCCAACATTCCTATGATGGGCACTCACATGCCAATGGCTGGA
  GACATGAATGGACTCAGCCCCACCCAAGCTCTTCCTCCTCCACTCTCCATGCCCTCCACCTCCCACTGCA
  CCCCCCCACCTCCGTACCCAACAGACTGCAGCATTGTCAGGATTTGGCAAGTCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001127343
• ORF Size: 1386 bp
• Insert Size: 1386
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001127343.1, NP_001120815.1
• RefSeq Size: 4468
• RefSeq ORF: 1386
• Locus ID: 246334
• Gene Summary: This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Both alternative splicing and the use of alternative promoters result in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Dec 2009]
  Transcript Variant: This variant (5) is an alternate promoter product; it lacks several 5' exons and an internal exon in the 3' region, but has an alternate 5' exon, as compared to variant 1. The resulting isoform (e, also known as deltaNKETbeta) has shorter and different N- and C-termini, as compared to isoform a.