Thra (NM_031134) Rat Untagged Clone

CAT#: RN200270

Thra (untagged ORF) - Rat thyroid hormone receptor alpha (Thra), transcript variant TRalpha2, (10 ug)

Specifications

Product Data

• Type: Rat Untagged Clone
• Tag: Tag Free
• Symbol: Thra
• Synonyms: c-erbA-1; ERBA1; Thra1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >RN200270 representing NM_031134
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAACAGAAGCCAAGCAAGGTGGAGTGTGGGTCAGACCCAGAGGAGAACAGTGCCAGGTCACCAGATG
  GAAAGCGAAAAAGGAAGAACGGCCAATGTCCCCTGAAAAGCAGCATGTCAGGGTATATCCCTAGTTACCT
  GGACAAAGACGAGCAGTGTGTCGTGTGTGGGGACAAGGCCACCGGTTATCACTACCGCTGTATCACTTGT
  GAGGGCTGCAAGGGCTTCTTTCGCCGTACAATCCAGAAGAACCTCCATCCCACCTATTCCTGCAAATATG
  ACAGCTGCTGCGTCATCGACAAGATCACCCGGAATCAGTGCCAGTTGTGCCGCTTCAAGAAGTGCATCGC
  TGTGGGCATGGCCATGGACCTGGTTCTAGACGATTCAAAGCGGGTGGCCAAACGCAAGCTGATTGAGCAG
  AACCGGGAGAGGAGGCGAAAGGAGGAGATGATCCGCTCGCTGCAGCAACGACCAGAGCCCACTCCTGAAG
  AGTGGGATCTGATCCACGTTGCTACAGAGGCCCATCGCAGCACCAATGCCCAGGGCAGCCATTGGAAACA
  GAGGCGAAAATTCCTGCCGGATGACATTGGCCAGTCACCTATTGTCTCCATGCCGGACGGAGACAAGGTA
  GACCTAGAGGCCTTCAGCGAGTTTACCAAGATCATCACCCCGGCCATCACCCGCGTGGTGGACTTTGCCA
  AAAAACTGCCCATGTTCTCCGAGCTGCCTTGTGAAGACCAGATCATCCTCCTGAAGGGCTGCTGCATGGA
  GATCATGTCCCTGCGGGCAGCTGTCCGCTATGACCCTGAGAGCGACACCCTGACCCTGAGTGGGGAGATG
  GCGGTTAAGCGGGAGCAGCTCAAGAATGGTGGCTTGGGTGTAGTCTCCGACGCCATCTTTGAACTGGGCA
  AGTCACTCTCTGCCTTTAACCTGGATGATACGGAAGTGGCTCTGCTGCAGGCTGTGCTGTTAATGTCAAC
  AGACCGCTCTGGCCTGCTGTGTGTGGACAAGATCGAGAAGAGTCAGGAGGCCTACCTGCTGGCGTTTGAG
  CACTACGTCAACCACCGCAAACACAACATTCCGCACTTCTGGCCCAAGCTGCTGATGAAGGAGAGAGAAG
  TGCAGAGTTCGATTCTGTACAAGGGGGCAGCGGCAGAAGGCCGGCCGGGCGGGTCACTGGGCGTCCACCC
  GGAAGGACAGCAGCTTCTCGGAATGCATGTTGTTCAGGGTCCGCAGGTCCGGCAGCTTGAGCAGCAGTTT
  GGTGAAGCGGGAAGTCTCCGAGGGCCGGTTCTTCAGCACCAGAGCCCGAAGAGCCCGCAGCAGCGTCTCC
  TGGAGCTGCTCCACCGAAGCGGAATTCTCCATTCCCGAGCGGTCTGTGGGGAAGACGACAGCAGTGAGGC
  AAGCTCCCTGAGCTCCTCTTCCTCTGACGAGGACACGGAGGTCTGCGAGGACCTGGCAGGCAAGGCAGCC
  TCTCCCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_031134
• ORF Size: 1479 bp
• Insert Size: 1479
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_031134.2, NP_112396.2
• RefSeq Size: 2268
• RefSeq ORF: 1479
• Locus ID: 81812
• Gene Summary: binds the promoter of the Na+/H+ exchanger NHE1 and mediates thyroid hormone induced transcriptional activation [RGD, Feb 2006]
  Transcript Variant: This variant (TRalpha2) contains an alternate 3' terminal exon compared to variant TRalpha1. The resulting protein (c-erbAalpha2, also known as TRalpha 2) has a distinct C-terminus compared to isoform TRalpha1, and fails to bind thyroid hormones or to trans-activate thyroid hormone responsive genes.