Scn2a (NM_012647) Rat Untagged Clone

CAT#: RN206256

Scn2a1 (untagged ORF) - Rat sodium channel, voltage-gated, type II, alpha 1 (Scn2a1), (10 ug)


  "NM_012647" in other vectors (1)

Reconstitution Protocol

USD 4,070.00

11 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Rat Untagged Clone
Tag Tag Free
Symbol Scn2a
Synonyms NachII; Nav1.2; RII/RIIA; RNSCPIIR; SCN; Scn2a1; Scn2a2; ScpII
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>RN206256 representing NM_012647
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGCACGGTCAGTGCTGGTACCTCCAGGACCTGACAGCTTCCGCTTCTTTACCAGGGAATCCCTTGCTG
CTATCGAACAGCGCATTGCAGAAGAGAAAGCTAAGAGACCCAAACAGGAACGCAAGGACGAAGACGATGA
AAATGGCCCAAAGCCAAATAGTGACTTGGAAGCAGGAAAATCCCTTCCTTTTATTTATGGAGACATTCCT
CCAGAGATGGTGTCAGAACCACTGGAGGACCTGGACCCCTACTATATCAATAAGAAAACCTTTATAGTAT
TGAATAAGGGGAAAGCAATCTCGCGGTTCAGCGCCACCTCTGCCCTGTACATTTTAACTCCCTTCAACCC
CATTAGAAAATTAGCTATTAAGATTTTGGTACATTCTTTATTCAATGTGCTTATCATGTGCACAATTCTT
ACCAACTGTGTGTTTATGACCATGAGTAACCCTCCAGACTGGACAAAGAATGTGGAGTATACTTTTACAG
GAATTTATACTTTTGAATCACTTATTAAAATCCTTGCAAGGGGCTTTTGTCTAGAAGATTTCACATTTCT
ACGGAATCCCTGGAATTGGTTGGATTTCACAGTCATTACTTTTGCGTATGTAACAGAATTTGTAAACCTA
GGCAATGTTTCAGCTCTTCGAACTTTCAGAGTCTTGAGAGCTTTGAAAACTATTTCTGTAATTCCAGGCC
TGAAGACTATCGTGGGGGCCCTGATCCAGTCAGTGAAGAAGCTCTCTGACGTCATGATCCTCACCGTGTT
CTGTCTCAGTGTCTTTGCTCTAATCGGGCTGCAGCTCTTCATGGGCAACCTGAGGAATAAATGCTTGCAG
TGGCCCCCAGACAATTCTACCTTTGAAATAAATATCACTTCCTTCTTTAATAACTCATTGGATTGGAATG
GTACTGCCTTCAATAGGACGGTGAACATGTTTAACTGGGACGAATATATTGAAGATAAAAGTCACTTTTA
TTTTTTGGAAGGACAAAACGATGCTCTGCTTTGTGGGAACAGCTCGGATGCTGGACAGTGTCCAGAAGGA
TACATCTGTGTGAAGGCTGGGAGAAACCCCAACTACGGCTACACAAGTTTTGACACCTTCAGCTGGGCCT
TCTTGTCCTTATTTCGTCTCATGACTCAAGACTTCTGGGAAAACCTTTATCAGCTGACCTTGCGTGCTGC
CGGGAAAACATACATGATATTTTTTGTGCTGGTCATTTTCTTGGGCTCATTCTACCTGATAAATTTGATC
CTGGCTGTGGTGGCCATGGCCTACGAGGAACAGAACCAGGCCACACTGGAGGAGGCTGAACAGAAGGAGG
CAGAGTTTCAGCAGATGCTGGAGCAACTGAAGAAGCAGCAGGAGGAAGCTCAGGCAGCAGCTGCAGCAGC
GTCCGCAGAATCCAGAGACTTCAGCGGGGCAGGCGGGATAGGTGTTTTCTCGGAGAGTTCGTCAGTAGCC
TCAAAGTTAAGTTCCAAAAGTGAAAAGGAGTTGAAAAACAGAAGAAAGAAAAAGAAACAGAAAGAACAGG
CTGGGGAGGAAGAGAAGGAAGACGCGGTGCGGAAATCTGCCTCTGAGGACAGCATACGAAAGAAAGGCTT
CCAGTTTTCCCTGGAAGGAAGTAGATTGACCTACGAGAAGAGATTTTCCTCTCCGCACCAGTCTCTCTTG
AGCATCCGAGGCTCCCTATTTTCTCCAAGACGCAACAGTAGAGCAAGCCTTTTCAACTTCAAAGGTCGAG
TGAAGGATATTGGTTCCGAAAATGACTTTGCAGACGATGAACACAGCACATTTGAGGACAACGACAGCAG
AAGAGACTCTCTATTTGTACCACACAGACATGGAGAAAGGCGTCCTAGCAATGTCAGCCAGGCCAGCCGT
GCCTCCCGGGGGATACCCACTCTACCCATGAATGGGAAGATGCACAGTGCAGTGGACTGCAACGGTGTGG
TGTCCCTGGTTGGAGGCCCCTCTGCGCTCACATCGCCTGTGGGGCAGCTGCTGCCGGAGGGCACAACTAC
TGAGACAGAAATAAGGAAGAGGAGATCCAGTTCTTACCACGTCTCTATGGACTTGTTGGAAGACCCTTCA
AGGCAAAGGGCAATGAGTATGGCCAGTATTTTGACGAACACTATGGAAGAACTTGAAGAATCCAGACAGA
AATGCCCACCCTGCTGGTATAAATTTGCTAATATGTGCCTGATTTGGGACTGTTGTAAGCCATGGCTAAA
GGTAAAACACGTTGTCAATCTGGTAGTGATGGATCCATTTGTTGACCTGGCCATCACCATCTGCATTGTG
TTAAATACGCTCTTCATGGCCATGGAGCACTACCCCATGACTGAGCAGTTCAGCAGTGTGCTGTCTGTTG
GGAATTTGGTCTTCACTGGGATCTTCACGGCAGAAATGTTTCTCAAGATAATAGCCATGGATCCATATTA
TTACTTCCAAGAAGGCTGGAATATCTTTGATGGCTTTATAGTGAGCCTTAGTTTAATGGAACTCGGCTTG
GCGAATGTGGAAGGATTGTCAGTTCTCCGATCATTCCGGCTGCTTAGAGTCTTCAAGTTGGCAAAGTCCT
GGCCCACACTGAACATGCTCATTAAGATCATCGGCAACTCGGTGGGTGCACTGGGCAACCTGACCCTGGT
GCTGGCCATCATCGTCTTCATTTTTGCCGTGGTCGGCATGCAGCTGTTTGGAAAGAGCTACAAGGAGTGT
GTCTGTAAGATTTCCAATGATTGTGAGCTCCCGCGCTGGCACATGCACCACTTCTTCCACTCCTTCCTGA
TCGTGTTTCGAGTCCTGTGTGGGGAGTGGATAGAGACCATGTGGGACTGCATGGAGGTCGCGGGCCAGAC
CATGTGCCTTACTGTCTTCATGATGGTCATGGTGATTGGGAACCTTGTTGTCCTGAACCTCTTCTTGGCC
TTGCTCCTCAGTTCTTTCAGCTCAGACAACCTGGCTGCCACAGATGACGATAACGAAATGAACAACCTCC
AGATAGCCGTGGGAAGGATGCAGAAGGGAATTGATTTTGTTAAAAGGAAGATACGTGAATTCATTCAGAA
AGCCTTTGTCAGAAAGCAGAAAGCTTTAGATGAAATCAAACCGCTGGAAGATCTGAATAACAAGAAAGAC
AGTTGTATCTCCAACCACACGACCATAGAAATAGGCAAGGACCTCAATTACCTCAAAGATGGAAACGGGA
CGACCAGTGGCATAGGCAGCAGTGTGGAGAAGTATGTGGTAGATGAGAGTGATTACATGTCGTTCATAAA
CAACCCCAGCCTCACCGTGACTGTGCCCATCGCCCTTGGAGAGTCTGACTTTGAAAACTTAAACACGGAA
GAATTCAGTAGTGAGTCAGATATGGAAGAAAGCAAGGAGAAATTGAATGCAACTAGCTCATCTGAGGGCA
GTACGGTTGATATAGGCGCTCCGGCAGAGGGAGAGCAGCCAGAGGCCGAACCGGAAGAATCGCTTGAACC
GGAAGCGTGTTTCACAGAAGACTGTGTGAGAAAGTTCAAGTGTTGTCAGATAAGCATAGAAGAGGGCAAA
GGCAAGCTCTGGTGGAACTTGAGGAAAACGTGCTACAAGATAGTAGAGCATAACTGGTTTGAAACCTTCA
TCGTTTTTATGATTCTGCTCAGCAGTGGTGCTCTGGCCTTTGAAGACATTTATATTGAGCAGCGAAAGAC
CATCAAGACCATGCTGGAGTATGCTGACAAGGTTTTCACTTATATCTTCATCCTGGAGATGCTTCTAAAG
TGGGTGGCCTATGGTTTCCAAATGTATTTCACCAATGCCTGGTGCTGGCTGGACTTCCTGATCGTTGATG
TCTCCTTGGTTAGCTTAACTGCAAATGCCTTGGGCTATTCGGAACTTGGTGCCATCAAGTCCCTCCGAAC
GTTAAGAGCTCTGAGACCTCTACGAGCCTTATCCCGATTTGAAGGAATGAGGGTTGTTGTAAACGCTCTC
TTAGGCGCCATCCCCTCCATAATGAACGTACTTCTGGTCTGCCTGATCTTTTGGCTAATATTCAGTATCA
TGGGGGTGAATCTCTTTGCTGGCAAGTTCTACCATTGCATCAACTACACCACGGGGGAAATGTTTGATGT
GAGCGTGGTCAACAACTACAGTGAATGCCAAGCTCTCATTGAGAGCAATCAGACGGCCAGGTGGAAGAAC
GTGAAGGTCAACTTCGATAACGTGGGACTCGGATACCTTTCTCTGCTCCAAGTAGCCACCTTTAAAGGAT
GGATGGATATCATGTATGCAGCTGTTGACTCAAGAAATGTAGAACTGCAGCCCAAATACGAAGACAATCT
CTACATGTACCTTTACTTTGTCATCTTCATCATCTTCGGCTCATTCTTCACCCTGAACCTGTTCATTGGT
GTCATCATAGACAACTTCAACCAGCAGAAGAAGAAGTTTGGAGGTCAAGACATCTTTATGACAGAAGAAC
AGAAGAAATACTACAATGCAATGAAGAAGCTCGGCTCCAAGAAACCGCAGAAGCCCATTCCTCGGCCTGC
AAACAAATTTCAAGGGATGGTCTTTGATTTTGTAACCAAACAAGTCTTTGACATCAGCATCATGATCCTC
ATCTGCCTCAACATGGTGACCATGATGGTGGAAACGGACGACCAGAGTCAGGAGATGACCAACATCCTGT
ACTGGATCAACCTGGTGTTCATTGTCCTGTTCACGGGCGAGTGTGTGCTGAAGCTCATCTCCCTCCGCCA
TTATTATTTCACCATCGGCTGGAATATTTTTGATTTTGTGGTAGTCATCCTCTCCATTGTAGGAATGTTT
CTCGCGGAGCTGATAGAGAAGTATTTCGTGTCCCCTACCCTGTTCCGAGTCATCCGCCTGGCCAGGATTG
GACGAATCCTACGCCTGATCAAAGGCGCCAAGGGGATCCGCACTCTGCTCTTTGCTCTGATGATGTCCCT
TCCTGCGCTGTTCAACATCGGCCTCCTGCTTTTCCTGGTCATGTTCATCTACGCCATCTTTGGGATGTCC
AACTTTGCCTACGTTAAGAGGGAAGTTGGAATTGATGACATGTTCAACTTTGAGACTTTTGGCAACAGCA
TGATCTGCCTGTTCCAAATCACCACCTCTGCCGGCTGGGACGGACTGCTGGCCCCTATACTAAATAGCGG
ACCTCCTGACTGTGACCCTGAAAAAGATCACCCTGGAAGCTCGGTGAAGGGGGACTGTGGGAACCCATCT
GTGGGGATTTTCTTTTTTGTCAGCTACATCATCATATCCTTCCTGGTGGTGGTGAACATGTACATCGCTG
TCATCCTGGAGAACTTCAGCGTCGCCACCGAAGAAAGTGCAGAGCCTCTGAGTGAGGACGACTTTGAGAT
GTTCTACGAGGTCTGGGAGAAGTTCGACCCTGACGCCACTCAGTTCATAGAGTTCTGCAAGCTTTCTGAC
TTTGCAGCTGCCCTGGATCCTCCCCTCCTCATCGCAAAGCCAAACAAAGTCCAGCTCATTGCCATGGACC
TGCCCATGGTGAGTGGAGACCGCATCCACTGCCTGGACATCTTGTTTGCTTTTACAAAGCGGGTCCTGGG
CGAGAGTGGAGAGATGGACGCTCTTCGAATCCAGATGGAAGAAAGGTTCATGGCTTCCAACCCCTCCAAG
GTCTCTTATGAGCCCATTACCACCACCCTGAAACGGAAACAAGAGGAGGTGTCTGCTATTGTCATCCAGC
GAGCATACAGGCGGTATCTCCTGAAGCAGAAAGTTAAGAAAGTTTCGTCTATCTATAAAAAAGACAAAGG
TAAAGAAGACGAGGGAACGCCCATCAAAGAAGACATCATCACAGATAAACTGAACGAGAATTCAACTCCA
GAGAAGACTGATGTGACACCTTCCACAACTTCTCCACCTTCCTACGATAGCGTGACGAAACCGGAGAAGG
AAAAATTTGAAAAGGACAAATCAGAAAAAGAGGACAAAGGGAAAGATATCAGGGAAAGTAAAAAGTAA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_012647
ORF Size 6018 bp
Insert Size 6018
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_012647.1, NP_036779.1
RefSeq Size 8553
RefSeq ORF 6018
Locus ID 24766
Gene Summary Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. In humans, variants of this gene are associated with seizure disorders and autism spectrum disorder. Mice homozygous for a knockout mutation die with severe hypoxia and extensive neuronal cell death, while gain of function mutations result in progressive seizure disorder. [provided by RefSeq, Nov 2016]

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