Myc (NM_012603) Rat Untagged Clone

CAT#: RN207206

Myc (untagged ORF) - Rat myelocytomatosis oncogene (Myc), (10 ug)

Specifications

Product Data

• Type: Rat Untagged Clone
• Tag: Tag Free
• Symbol: Myc
• Synonyms: c-myc; mMyc; RNCMYC
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >RN207206 representing NM_012603
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  CTGAATTTCCTTTGGGAGGTGGAAAACCCGACAGTCACGACGATGCCCCTCAACGTGAGCTTCGCTAACA
  GGAACTATGACCTCGACTACGACTCGGTGCAGCCCTATTTCATCTGCGACGAGGAAGAGAATTTCTATCA
  CCAGCAACAGCAGAGCGAGCTGCAGCCGCCCGCACCCAGTGAGGATATCTGGAAGAAATTCGAGCTGCTG
  CCCACCCCGCCCCTGTCCCCCAGCCGCCGCTCCGGGCTCTGCTCTCCGTCCTATGTTGCGGTCGCTACGT
  CCTTCTCCCCAAGGGAGGACGATGACGGTGGCGGTGGCAACTTCTCCACCGCCGATCAGCTGGAGATGAT
  GACCGAGCTACTTGGAGGAGACATGGTGAATCAGAGCTTCATCTGCGATCCTGACGATGAGACCTTCATC
  AAGAACATCATCATCCAGGACTGTATGTGGAGCGGCTTCTCGGCCGCTGCCAAACTGGTCTCCGAGAAGC
  TGGCCTCTTACCAGGCTGCGCGCAAAGACAGCACCAGCCTGAGCCCCGCCCGCGGGCACAGCGTCTGCTC
  CACCTCCAGCCTGTACCTGCAGGACCTCACCGCCGCAGCGTCCGAGTGCATCGACCCCTCAGTGGTCTTC
  CCCTACCCGCTCAACGACAGCAGCTCGCCCAAATCCTGTACCTCGTCCGATTCCACGGCCTTCTCTTCTT
  CCTCGGACTCGCTGCTGTCCTCCGAGTCCTCCCCACGGGCCACCCCTGAGCCCCTAGTGCTGCATGAAGA
  GACACCGCCCACCACCAGCAGCGACTCTGAAGAAGAACAAGATGATGAGGAAGAAATTGATGTGGTGTCT
  GTGGAAAAGAGGCAACCCCCTGCCAAGAGGTCCGAGTCAGGGTCATCCCCATCAAGAGGCCACAGCAAAC
  CTCCACACAGCCCACTGGTCCTCAAGAGGTGCCATGTCTCTACTCACCAGCACAATTATGCAGCACCCCC
  CTCCACAAGGAAGGACTATCCAGCTGCCAAGAGGGCCAAGTTGGACAGTGGCAGGGTCCTGAAACAGATC
  AGCAACAACCGCAAATGCTCCAGCCCCAGGTCCTCAGACACCGAGGAAAACGACAAGAGGCGGACACACA
  ACGTCTTGGAACGTCAGAGGAGAAACGAGCTGAAGCGTAGCTTTTTTGCCCTGCGCGACCAGATCCCTGA
  GTTGGAAAACAACGAAAAGGCCCCCAAGGTAGTTATCCTCAAAAAAGCCACCGCCTACATCCTGTCCGTT
  CAAGCAGATGAGCACAAACTCATCTCAGAAAAGGACTTACTGAGGAAACGGCGAGAACAGTTGAAACACA
  AACTCGAACAGCTTCGAAACTCTGGTGCATAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_012603
• ORF Size: 1362 bp
• Insert Size: 1362
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_012603.2, NP_036735.2
• RefSeq Size: 2355
• RefSeq ORF: 1362
• Locus ID: 24577
• Gene Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma, in human. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini, in human and mouse. Rat mRNA also has a similarly placed CUG upstream of the AUG start site, suggesting that it may also produce two Myc proteins. [provided by RefSeq, Jul 2008]