Nrxn1 (NM_021767) Rat Untagged Clone

CAT#: RN208761

Nrxn1 (untagged ORF) - Rat neurexin 1 (Nrxn1), (10 ug)

Specifications

Product Data

• Type: Rat Untagged Clone
• Tag: Tag Free
• Symbol: Nrxn1
• Synonyms: Nrxn1b
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >RN208761 representing NM_021767
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGGACGGCGCTGGTCCAGCATGGGGGCTGCTGTCTCCTCTGCCTGTCGCTGCTGCTGTTGGGCTGCT
  GGGCAGAGCTGGGCAGTGGGCTGGAGTTCCCAGGCGCTGAGGGCCAGTGGACGCGCTTCCCCAAGTGGAA
  CGCGTGCTGCGAGAGTGAGATGAGCTTCCAGCTGAAGACACGCAGCGCCCGCGGCCTCGTGCTCTACTTC
  GACGACGAGGGCTTCTGCGACTTCCTCGAGCTCATCCTGACACGCGGCGGCCGCTTGCAGCTCAGCTTCT
  CCATCTTCTGCGCCGAGCCCGCCACGCTGTTGGCCGACACGCCAGTCAACGACGGCGCCTGGCACAGCGT
  GCGCATCCGCCGCCAGTTCCGCAACACCACTCTCTACATCGACCGCGCTGAGGCCAAGTGGGTGGAGGTC
  AAGTCCAAGCGCAGGGACATGACGGTGTTCAGTGGGCTGTTCGTGGGCGGCCTGCCGCCTGAACTGCGAG
  CCGCTGCGCTCAAGCTCACCCTGGCCTCGGTGCGTGAGCGGGAGCCCTTCAAGGGCTGGATCCGTGATGT
  CAGGGTCAACTCGTCCCAGGCGCTGCCGGTGGACGGCAGCGAGGTCAAGCTGGACGAAGAGCCGCCCAAT
  AGCGGGGGCGGGAGCCCGTGCGAGGCGGGCGATGAGGGCGACGGCGGCGTGTGCCTCAACGGGGGCGTGT
  GCTCCGTGGTCGACGACCAGGCCGTGTGTGACTGCTCGAGGACCGGTTTCCGTGGCAAAGACTGCAGCCA
  AGAAGACAACAATGTAGAAGGTCTGGCGCACCTGATGATGGGCGACCAAGGTAAAAGTAAAGGAAAAGAA
  GAGTATATTGCCACATTCAAGGGATCTGAGTACTTCTGCTACGACTTATCCCAAAACCCCATTCAAAGCA
  GCAGCGACGAAATAACTCTGTCCTTTAAAACTCTTCAGAGGAATGGACTGATGCTTCACACAGGGAAATC
  GGCTGATTATGTCAACCTTGCCTTGAAAAATGGAGCTGTCTCTCTGGTCATTAATTTGGGATCAGGGGCC
  TTTGAAGCGCTAGTAGAGCCCGTGAATGGAAAGTTTAATGATAATGCCTGGCATGATGTGAAAGTCACCA
  GGAATCTGCGTCAGCACTCAGGCATTGGACACGCTATGGTGACAATATCAGTGGATGGGATTCTTACCAC
  AACGGGCTACACGCAAGAAGATTACACCATGCTGGGGTCTGATGACTTTTTCTATGTTGGAGGCAGCCCC
  AGCACAGCCGACCTTCCAGGGTCACCAGTCAGTAACAACTTTATGGGCTGTCTCAAAGAGGTCGTATATA
  AAAATAATGATGTAAGACTGGAGTTATCGCGACTTGCCAAGCAAGGAGATCCTAAGATGAAGATCCATGG
  TGTGGTGGCTTTTAAGTGTGAAAATGTGGCAACCTTAGACCCAATCACTTTTGAGACCCCAGAATCTTTC
  ATTTCTTTGCCTAAGTGGAATGCAAAGAAAACAGGCTCAATATCATTTGATTTCCGTACAACGGAGCCAA
  ATGGCCTCATCTTGTTTAGCCATGGCAAGCCAAGACATCAGAAGGATGCCAAGCACCCGCAGATGATTAA
  GGTTGACTTTTTTGCTATTGAAATGCTGGATGGCCACTTGTACCTCCTCTTAGACATGGGATCAGGTACT
  ATAAAAATCAAAGCCCTTCAGAAGAAAGTCAATGATGGAGAATGGTATCACGTGGATTTCCAGCGAGATG
  GACGGTCAGGTACCATTTCTGTCAACACACTTCGTACTCCCTACACAGCTCCCGGTGAGAGTGAGATCCT
  AGACCTCGATGATGAGTTGTATCTGGGTGGCTTGCCAGAAAATAAGGCTGGCCTGGTCTTCCCCACTGAG
  GTGTGGACTGCTCTGCTCAACTATGGCTACGTAGGCTGCATCCGGGATCTATTCATTGATGGCCAGAGCA
  AAGATATCCGGCAGATGGCGGAAATTCAGAGTACTGCTGGAGTGAAGCCATCCTGCTCAAGGGAGACTGC
  AAAACCATGCCTTAGCAATCCTTGCAAAAACAATGGCATGTGCAGGGATGGCTGGAACAGATACGTCTGT
  GATTGCTCTGGAACAGGCTATCTCGGCAGGTCCTGTGAGAGAGAGGCAACGGTTTTGAGCTACGATGGGA
  GTATGTTTATGAAAATTCAGCTCCCTGTGGTGATGCACACTGAGGCCGAGGACGTTTCCTTACGGTTCAG
  ATCCCAGCGTGCGTACGGCATTCTGATGGCGACCACTTCTAGAGACTCCGCAGATACCCTTCGACTGGAG
  CTAGATGCAGGGCGCGTGAAACTCACGGTCAATCTAGATTGTATCAGGATTAACTGTAATTCCAGCAAAG
  GTCCTGAGACCCTTTTTGCCGGCTATAACCTCAATGATAATGAATGGCACACAGTACGTGTGGTTCGGCG
  AGGAAAAAGTTTAAAGCTAACCGTGGATGATCAACAAGCCATGACAGGCCAAATGGCAGGTGATCATACA
  AGGCTGGAGTTTCATAACATAGAGACAGGCATCATCACAGAACGACGCTATCTTTCTTCTGTCCCCTCCA
  ACTTCATTGGGCACCTGCAAAGCCTCACATTTAATGGAATGGCATACATTGACTTGTGCAAAAATGGTGA
  TATAGATTATTGTGAACTCAATGCCAGGTTTGGATTCAGGAACATCATCGCGGATCCTGTCACCTTCAAG
  ACCAAATCAAGCTATGTTGCCTTAGCTACATTGCAAGCCTACACTTCTATGCATCTATTTTTCCAATTCA
  AGACAACATCCCTAGATGGACTAATTCTGTATAACAGTGGGGATGGAAATGACTTTATTGTGGTTGAATT
  AGTTAAAGGGTACTTACATTATGTGTTTGACTTGGGAAATGGTGCTAACCTCATCAAAGGGAGCTCAAAC
  AAACCACTCAACGACAATCAGTGGCACAATGTGATGATTTCAAGGGACACCAGCAATCTCCACACAGTAA
  AGATCGACACAAAAATCACAACACAAATCACTGCGGGAGCCAGAAACTTAGACCTCAAGAGTGACTTGTA
  TATTGGAGGAGTGGCTAAAGAAACATACAAATCGTTGCCGAAACTGGTCCATGCTAAAGAAGGCTTTCAA
  GGTTGCCTGGCATCTGTGGACTTGAATGGCAGGCTTCCAGACCTCATATCTGATGCTCTTTTCTGCAATG
  GGCAAATTGAGAGAGGATGCGAAGGGCCCAGCACAACCTGTCAAGAGGACTCATGTTCAAATCAAGGCGT
  GTGCTTGCAGCAATGGGATGGCTTTAGCTGTGACTGTAGCATGACTTCCTTCAGTGGCCCGCTCTGCAAT
  GACCCTGGGACGACGTATATCTTTAGCAAAGGTGGTGGACAAATTACACATAAGTGGCCTCCTAATGACC
  GACCCAGTACACGAGCAGACAGGCTGGCCATCGGGTTTAGCACTGTTCAGAAGGAAGCAGTGTTGGTGCG
  TGTGGACAGTTCCTCAGGCCTGGGTGACTACCTTGAGCTGCACATACACCAAGGAAAAATTGGAGTTAAA
  TTTAATGTTGGGACAGATGACATCGCCATTGAGGAGTCCAATGCAATCATTAATGATGGAAAATACCATG
  TAGTGCGTTTCACGAGGAGTGGTGGCAATGCCACGTTACAGGTGGACAGCTGGCCAGTCATCGAACGATA
  CCCTGCAGGAAACAATGATAACGAGCGCCTGGCGATTGCTAGACAGCGAATTCCATATCGACTTGGTCGA
  GTAGTTGATGAATGGCTACTCGACAAAGGGCGTCAGCTCACAATCTTCAATAGCCAAGCAACCATAATAA
  TTGGCGGGAAAGAGCAGGGCCAGCCCTTCCAGGGCCAGCTCTCTGGGCTTTACTACAATGGCTTGAAAGT
  TCTGAATATGGCGGCAGAAAACGATGCCAACATCGCCATAGTGGGAAATGTGAGGCTGGTCGGTGAAGTG
  CCTTCCTCTATGACAACTGAGTCGACAGCCACTGCCATGCAGTCCGAGATGTCCACCTCAATCATGGAGA
  CCACCACAACCCTGGCTACCAGCACAGCTCGACGAGGAAAGCCCCCCACAAAGGAGCCTATCAGCCAGAC
  CACGGATGATATCCTTGTGGCCTCGGCAGAGTGTCCCAGCGACGATGAGGACATTGACCCCTGTGAGCCG
  AGCTCAGGTGGGTTAGCCAACCCCACCCGAGTGGGCGGCCGCGAACCATACCCAGGCTCGGCAGAGGTGA
  TCCGGGAGTCTAGCAGTACCACTGGCATGGTGGTGGGGATTGTCGCAGCAGCAGCTCTGTGCATCCTCAT
  CCTCCTCTATGCCATGTACAAGTACAGAAACCGGGATGAAGGCTCATATCACGTGGATGAGAGTCGAAAC
  TACATCAGTAACTCAGCACAGTCCAATGGGGCTGTGGTCAAGGAGAAGCAGCCCAGCAGTGCGAAAAGCG
  CCAACAAAAACAAGAAGAACAAGGATAAGGAGTATTATGTCTGA
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-RsrII
• ACCN: NM_021767
• ORF Size: 4524 bp
• Insert Size: 4524
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_021767.2, NP_068535.2
• RefSeq Size: 5609
• RefSeq ORF: 4524
• Locus ID: 60391
• Gene Summary: This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are synaptic transmembrane receptors that bind endogenous ligands that include neuroligins, dystroglycan, and neurexophilins. Neurexin complexes are required for efficient neurotransmission and are involved in synaptogenesis. In vertebrates, alternate promoter usage results in multiple isoform classes, of which the alpha and beta classes are the best characterized. In humans, allelic variants in this gene are associated with Pitt-Hopkins-like syndrome-2, while deletions have been associated with autism and schizophrenia. Mouse knockouts display decreased spontaneous and evoked vesicle release resulting in impaired synaptic transmission. In addition, knockout mice show altered social approach, reduced social investigation, reduced locomotor activity, and in males, increased aggression. [provided by RefSeq, Nov 2016]