Dcx (NM_053379) Rat Untagged Clone

CAT#: RN211526

Dcx (untagged ORF) - Rat doublecortin (Dcx), (10 ug)

Specifications

Product Data

• Type: Rat Untagged Clone
• Tag: Tag Free
• Symbol: Dcx
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >RN211526 representing NM_053379
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAACTTGATTTTGGACATTTTGACGAACGAGACAAAGCATCTAGAAATATGAGAGGGTCACGGATGA
  ATGGACTTCCAAGTCCCACTCATAGTGCTCACTGTAGCTTCTACAGAACCAGAACCTTGCAGGCATTAAG
  TAATGAGAAGAAGGCCAAGAAGGTACGTTTCTACCGCAATGGGGACCGTTACTTCAAGGGGATTGTGTAC
  GCTGTTTCTTCTGACCGTTTTCGTAGTTTTGATGCATTGCTGGCTGACCTGACTCGATCCTTGTCCGACA
  ACATCAACCTGCCTCAGGGAGTGCGCTACATTTACACTATTGATGGATCCAGAAAGATTGGAAGCATGGA
  TGAACTGGAAGAAGGGGAAAGCTATGTCTGTTCCTCAGACAACTTCTTTAAAAAGGTTGAGTATACCAAG
  AATGTCAATCCCAACTGGTCGGTCAATGTAAAGACATCAGCCAACATGAAAGCGCCCCAGTCCTTGGCTA
  GCAGCAACAGTGCTCAAGCCAGAGAGAACAAGGACTTCGTGCGCCCCAAACTTGTGACCATCATTCGCAG
  TGGGGTGAAGCCTCGGAAGGCGGTGCGTGTGCTTCTCAACAAGAAAACAGCCCACTCTTTCGAGCAGGTC
  CTCACTGACATCACAGAAGCGATCAAACTGGAAACCGGAGTTGTCAAAAAACTCTATACCCTTGATGGAA
  AGCAGGTCACCTGTCTCCATGATTTCTTTGGTGATGATGATGTGTTCATTGCTTGTGGCCCTGAAAAGTT
  CCGCTATGCTCAAGATGACTTCTCCTTGGATGAGAATGAATGCAGAGTCATGAAAGGGAATCCATCTGCC
  ACAGCTGGCCCAAAAGCTTCCCCAACACCTCAAAAGACATCTGCTAAAAGCCCAGGCCCAATGCGCCGCA
  GCAAGTCTCCAGCTGACTCAGGTAACGACCAAGACGCAAATGGAACTTCTAGCAGTCAGCTCTCAACACC
  TAAGTCGAAGCAGTCTCCTATCTCTACACCCACAAGCCCTGGAAGTCTGCGGAAGCACAAGGACTTGTAC
  CTGCCACTGTCATTGGATGACTCTGATTCACTTGGCGATTCCATGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_053379
• ORF Size: 1098 bp
• Insert Size: 1098
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_053379.3, NP_445831.3
• RefSeq Size: 8827
• RefSeq ORF: 1098
• Locus ID: 84394
• Gene Summary: This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains, which bind microtubules and regulate microtubule polymerization. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. Studies in knockout mice lacking this gene suggest that this gene has a cortical role in nuclear translocation and positioning of the mitotic spindle in radial glial mitotic division. This gene is essential for neuronal migration, differentiation, and plasticity, is required for hippocampal development and also plays a role in dendrites development. [provided by RefSeq, Sep 2010]