Pdx1 (NM_022852) Rat Untagged Clone

CAT#: RN215611

Pdx1 (untagged ORF) - Rat pancreatic and duodenal homeobox 1 (Pdx1), (10 ug)

Specifications

Product Data

• Type: Rat Untagged Clone
• Tag: Tag Free
• Symbol: Pdx1
• Synonyms: Idx1; Ipf1; Stf1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >RN215611 representing NM_022852
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAATAGTGAGGAGCAGTACTACGCGGCCACACAGCTCTACAAGGACCCGTGCGCATTCCAGAGGGGTC
  CGGTGCCAGAGTTCAGTGCTAATCCCCCTGCGTGCCTGTACATGGGCCGCCAGCCCCCACCTCCGCCGAC
  ACCCCAGTTTGCAGGCTCGCTGGGAACGCTGGAACAGGGAAGTCCCCCGGACATCTCCCCATACGAAGTG
  CCCCCGCTCGCCGATGACCCGGCTGGCGCGCACCTCCACCACCACCTCCCAGCTCAGCTCGGGCTCGCCC
  ATCCACCTCCCGGACCTTTCCCGAATGGAACCGAGACTGGGGGCCTGGAAGAGCCCAGCCGCGTTCATCT
  CCCTTTCCCGTGGATGAAATCCACCAAAGCTCACGCGTGGAAAAGCCAGTGGGCAGGAGGTGCATACGCA
  GCAGAACCGGAGGAGAATAAGAGGACCCGTACAGCCTACACTCGGGCCCAGCTGCTGGAGCTGGAGAAGG
  AATTCTTATTTAACAAATACATCTCCCGGCCTCGCCGGGTGGAGCTGGCAGTGATGCTCAACTTGACTGA
  GAGACACATCAAAATCTGGTTCCAAAACCGTCGCATGAAGTGGAAGAAAGAGGAAGATAAGAAACGTAGT
  AGCGGGACAACGAGCGGGGGCGGTGGGGGCGAAGAGCCGGAGCAGGATTGTGCCGTAACCTCGGGCGAGG
  AGCTGCTGGCATTGCCAAAGCCACCACCTCCCGGAGGTGTTGTGCCCTCAGGCGTCCCTGCTGCTGCCCG
  GGAGGGCCGACTGCCTTCCGGCCTTAGTGCGTCCCCACAGCCCTCCAGCATCGCGCCACTGCGACCGCAG
  GAACCCCGGTGA
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-RsrII
• ACCN: NM_022852
• ORF Size: 852 bp
• Insert Size: 852
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_022852.3, NP_074043.3
• RefSeq Size: 1403
• RefSeq ORF: 852
• Locus ID: 29535
• Gene Summary: Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds the DNA sequence 5'-CC[CT]TAATGGG-3'. [UniProtKB/Swiss-Prot Function]