Gria4 (NM_001113184) Rat Untagged Clone

CAT#: RN217310

Gria4 (untagged) - Rat glutamate receptor, ionotropic, AMPA 4 (Gria4), transcript variant 2

Specifications

Product Data

• Type: Rat Untagged Clone
• Tag: Tag Free
• Symbol: Gria4
• Synonyms: GluA4; GluR-D; GluR4
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >RN217310 representing NM_001113184
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGGATTATTTGCAGGCAGATTGTCTTGTTGTTTTCTGGATTTTGGGGACTCGCCATGGGAGCCTTTC
  CAAGCAGCGTTCAAATAGGTGGTCTCTTCATCCGAAACACAGACCAGGAATACACTGCTTTTAGACTGGC
  AATCTTTCTTCATAACACCAGCCCCAATGCATCGGAAGCTCCTTTCAATTTGGTACCTCATGTGGACAAC
  ATTGAGACTGCCAACAGTTTTGCTGTGACAAACGCCTTCTGTTCCCAGTATTCTAGAGGGGTGTTTGCCA
  TTTTTGGACTCTATGACAAGAGATCCGTGCATACCTTGACCTCGTTCTGCAGTGCTCTGCACATCTCTCT
  CATCACACCAAGCTTTCCCACTGAAGGGGAGAGCCAGTTTGTGCTGCAGCTAAGACCTTCACTGAGAGGT
  GCACTCCTGAGCCTCCTGGATCACTATGAGTGGAACTGTTTCGTCTTCCTGTATGATACAGACAGGGGGT
  ATTCAATACTTCAAGCTATAATGGAAAAAGCAGGACAAAATGGATGGCATGTCAGTGCAATATGTGTGGA
  AAATTTTAATGATGTCAGCTACAGGCAACTGCTAGAAGAGCTTGACAGAAGACAAGAGAAGAAATTTGTG
  ATAGATTGTGAGATAGAGAGGCTTCAAAACATTTTAGAACAAATTGTGAGTGTTGGGAAGCATGTCAAAG
  GCTACCATTATATCATCGCAAATTTGGGTTTCAAGGATATTTCTCTTGAGAGATTTATACATGGAGGAGC
  AAATGTAACAGGATTCCAGTTGGTAGATTTTAATACACCCATGGTAACCAAACTAATGGATCGGTGGAAG
  AAACTAGATCAGAGAGAATATCCAGGTTCTGAAACACCTCCAAAGTACACCTCTGCTCTCACTTATGATG
  GAGTCCTGGTGATGGCTGAAACTTTCCGAAGTCTCAGAAGACAGAAAATTGATATTTCAAGGAGAGGAAA
  TGCTGGGGACTGTCTGGCAAACCCTGCTGCTCCCTGGGGCCAGGGAATTGACATGGAGAGGACACTGAAG
  CAGGTTCGAATTCAAGGGCTGACTGGGAATGTTCAATTTGACCATTATGGACGTAGAGTTAATTACACAA
  TGGATGTGTTTGAACTGAAAAGCACAGGACCTCGAAAGGTTGGCTACTGGAATGATATGGATAAATTAGT
  CTTGATTCAAGATATGCCTACTCTTGGCAATGACACAGCAGCTATTGAGAACAGAACAGTGGTTGTAACC
  ACAATTATGGAATCTCCCTATGTTATGTACAAGAAAAATCATGAAATGTTTGAAGGAAATGACAAGTACG
  AAGGCTACTGTGTAGATCTGGCATCGGAAATTGCAAAACATATTGGTATCAAATATAAAATTGCCATTGT
  TCCTGATGGAAAATATGGAGCAAGGGACGCAGACACTAAGATCTGGAATGGGATGGTAGGAGAGCTTGTG
  TATGGGAAAGCAGAGATTGCTATTGCCCCTCTGACAATCACATTGGTTCGAGAGGAAGTCATCGATTTTT
  CTAAGCCTTTTATGAGTTTAGGCATCTCTATCATGATCAAAAAACCTCAGAAATCTAAACCAGGAGTCTT
  TTCCTTCTTGGACCCTCTGGCCTATGAGATCTGGATGTGCATAGTGTTTGCATACATTGGTGTCAGTGTG
  GTCTTGTTCCTAGTCAGTAGGTTTAGCCCATATGAGTGGCACACAGAAGAACCTGAGGATGGGAAGGAAG
  GACCCAGTGACCAGCCTCCCAATGAATTTGGCATCTTTAACAGCCTTTGGTTTTCCCTGGGTGCCTTTAT
  GCAACAAGGATGTGACATTTCACCCAGATCCCTGTCAGGTCGGATTGTTGGAGGCGTGTGGTGGTTCTTC
  ACACTCATCATTATATCGTCCTACACTGCTAATCTGGCTGCATTCCTTACTGTGGAGAGAATGGTCTCCC
  CCATAGAAAGTGCAGAAGACCTGGCCAAACAAACAGAAATTGCCTATGGAACACTTGATTCTGGGTCAAC
  AAAAGAATTCTTCAGAAGATCAAAAATAGCAGTGTATGAAAAGATGTGGACCTACATGCGATCGGCAGAG
  CCGTCTGTGTTCACTAGAACTACAGCTGAGGGCGTGGCTCGTGTCCGCAAGTCCAAGGGCAAATTTGCCT
  TTCTCCTGGAGTCCACGATGAATGAATACATTGAGCAGCGAAAGCCCTGTGACACGATGAAAGTGGGAGG
  AAACCTGGATTCCAAAGGCTATGGTGTAGCAACGCCCAAGGGTTCCTCATTAAGAAATGCTGTTAACCTC
  GCAGTTTTAAAACTGAATGAACAAGGCCTCTTGGACAAATTGAAAAACAAATGGTGGTACGACAAAGGAG
  AATGTGGCAGCGGGGGAGGTGACTCCAAGGACAAGACGAGTGCCTTGAGCCTGAGCAACGTAGCAGGCGT
  CTTCTACATTCTGGTTGGCGGCCTGGGCTTGGCAATGCTGGTGGCTTTGATAGAGTTCTGTTACAAGTCC
  AGGGCAGAGGCGAAGAGAATGAAGCTGACTTTTTCCGAAGCCATAAGAAACAAAGCCAGGTTATCCATCA
  CTGGGAGTGTGGGAGAAAACGGCCGTGTGCTGACCCCTGACTGCCCCAAGGCCGTACACACAGGAACTGC
  AATTAGACAAAGTTCGGGATTGGCTGTCATTGCATCGGACCTACCATAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001113184
• ORF Size: 2709 bp
• Insert Size: 2709
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001113184.1, NP_001106655.1
• RefSeq Size: 4141
• RefSeq ORF: 2709
• Locus ID: 29629
• Gene Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) uses an alternate internal coding exon compared to transcript variant 1, and encodes an isoform (2, also known as flop isoform) that is the same length, but with a few amino acid differences compared to isoform 1. RNA editing (AGA->GGA) changes Arg765Gly.