Shank2 (NM_133441) Rat Tagged ORF Clone

CAT#: RR200192

Shank2 (Myc-DDK-tagged ORF) - Rat SH3 and multiple ankyrin repeat domains 2 (Shank2), transcript variant 4, (10 ug)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Shank2
• Synonyms: CortBP1; ProSAP1; Spank-3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR200192 representing NM_133441
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAGTCTTTGTTAAATGCCTTCACCAAGAAGGAAGTGCCCTTCCGAGAGGCCCCAGCTTATTCCAACC
  GCAGGCGGCGGCCCCCCAACACATTGGCTGCCCCCAGAGTTCTTCTGCGTTCCAATAGCGACAACAACCT
  CAATGCCGGTGCGCCTGAATGGGCTGTCTGCTCTGCAGCCACCTCCCACCGAAGCCTCTCACCCCAGCTG
  CTGCAGCAGACACCCAGCAAACCTGATGGAGCCACAAAGAGCCTTGGAAGCTACGCCCCTGGGCCCCGCA
  GCCGCTCTCCCTCACTCAACAGGCTGGGTGGCGCTGGTGAGGATGGCAAGAGGCCACAGCCGCCACATTG
  GCATGTGGGGTCGCCCTTCACTCCTGGTGCCAACAAGGACTCCCTCTCGACCTTTGAGTACCCAGGGCCC
  CGGAGGAAGCTGTATAGTGCGGTGCCTGGGAGACTCTTCGTCGCCATCAAGCCATACCAACCCCAAGTCG
  ACGGCGAGATCCCCCTTCACCGAGGCGACAGGGTCAAAGTTCTGAGCATCGGCGAGGGCGGCTTCTGGGA
  AGGCAGCGCCCGTGGCCACATCGGGTGGTTCCCAGCTGAGTGTGTGGAGGAGGTACAATGTAAGCCCCGG
  GACAGCCAAGCAGAAACCCGTGCGGACCGCAGCAAGAAGCTCTTTCGGCATTACACAGTGGGCTCCTATG
  ACAGCTTTGATGCTGCCAGTGACTGCATTATTGAGGACAAGACGGTGGTCCTGCAGAAGAAAGACAACGA
  GGGCTTTGGATTTGTGCTCCGAGGGGCAAAAGCTGATACCCCCATTGAGGAATTCACACCCACGCCGGCA
  TTTCCAGCCCTGCAGTACCTGGAGTCCGTGGATGAAGGAGGGGTGGCATGGCAAGCCGGACTAAGGACCG
  GGGACTTCTTGATTGAGGTTAACAATGAAAATGTCGTCAAGGTGGGCCACAGGCAGGTGGTGAACATGAT
  CCGCCAGGGAGGGAATCACCTCGTCCTTAAGGTCGTCACGGTGACCAGGAATCTAGACCCTGATGATACA
  GCCAGAAAGAAAGCTCCCCCACCTCCAAAGCGGGCTCCGACCACGGCCCTCACCCTGCGTTCCAAGTCCA
  TGACAGCGGAATTGGAGGAACTCGTGGATAAAGCCTCAGTCCGGAAGAAGAAGGATAAACCGGAAGAGAT
  AGTCCCAGCCTCCAAGCCCTCCAGGACTGCAGAGAACGTGGCCATAGAATCCAGGGTGGCAACCATCAAG
  CAGCGGCCCACAAGCCGGTGCTTTCCAGCTGCCTCTGATGTGAACTCCGTGTACGAGCGCCAAGGGATTG
  CTGTAATGACGCCCACGGTCCCTGGGAGCCCGAAAGGCCCATTTCTGGGCCTCCCTCGAGGTACGATGCG
  AAGGCAGAAATCGATAGACAGCAGAATCTTTCTATCAGGGATAACAGAGGAAGAGCGGCAGTTTCTGGCT
  CCCCCAATGCTGAAGTTCACCCGAAGCTTGTCCATGCCAGACACTTCTGAGGACATCCCCCCTCCGCCAC
  AGTCTGTGCCCCCCTCTCCCCCTCCACCTTCCCCCACCACATACAACTGTCCCAGGTCCCCGACTCCAAG
  AGTCTATGGGACAATTAAGCCTGCGTTCAACCAGAACCCCGTCGCCAAGGTGCCCCCAGCCACCAGGTCT
  GACACTGTGGCCACCATGATGCGGGAAAAGGGGATGTTCTACAGGAGAGAGCTGGACCGCTTTTCCCTGG
  ACTCAGAAGACGTCTACAGCCGCAGCCCCGCCCCACAGGCTGCCTTCCGCACCAAGCGGGGACAGATGCC
  TGAGAACCCGTACTCGGAGGTGGGAAAGATAGCCAGCAAGGCCGTCTATGTCCCTGCCAAGCCAGCCAGG
  CGGAAGGGCATGCTGGTAAAGCAGTCCAACGTGGAGGACAGCCCTGAGAAGACGTGCTCCATCCCCATCC
  CAACCATCATAGTCAAGGAACCCTCCACCAGCAGCAGCGGCAAGAGCAGCCAGGGGAGCAGCATGGAGAT
  CGACCCCCAGGCCACTGAGCCCGGCCAGCTGCGGCCAGATGACAGCCTCACCGTCAGCAGCCCCTTCGCG
  GCAGCCATCGCTGGGGCCGTGCGTGACCGGGAGAAGCGTCTGGAAGCCAGGAGGAATTCCCCGGCCTTCC
  TCTCCACCGACCTGGGAGATGAGGACGTGGGTCTGGGGCCTCCTGCTCCCCGGATGCAGCCCTCCAAGTT
  TCCCGAGGAGGGTGGGTTTGGTGATGAGGATGAAACGGAACAGCCGCTATTGCCTACCCCTGGAGCAGCG
  CCCAGGGAGCTGGAGAACCACTTCCTAGGTGGTGGTGAGGCTGGTGCTCAGGGGGAGGCTGGGGGACCCC
  TGAGTTCCACATCCAAAGCCAAGGGGCCTGAAAGTGGCCCAGCAGCCGCCCTCAAGAGCAGCAGCCCAGC
  CAGCCCTGAGAATTACGTGCACCCACTCACGGGGCGGCTGCTCGACCCCAGCTCCCCGCTGGCCCTGGCA
  CTGTCCGCCAGGGACCGAGCCATGCAGGAGTCCCAGCAAGGACACAAGGGGGAGGCCCCCAAGGCCGACC
  TTAACAAGCCTCTCTACATCGATACCAAAATGCGGCCCAGTGTGGAGTCCGGCTTTCCACCGGTCACCAG
  ACAGAACACCAGGGGTCCCCTGCGAAGGCAGGAGACAGAGAACAAGTATGAGACGGACCTGAGCAAGGAC
  CGGAGGGCTGACGACAAGAAGAACATGCTGATCAACATCGTGGACACTGCCCAGCAGAAGTCAGCCGGCC
  TACTGATGGTGCACACAGTGGACATTCCCGTGGCGGGGCCACCCCTGGAGGAAGAGGAGGACAGAGAGGA
  TGGGGATACAAAGCCAGACCACTCACCCTCCACAGTGCCAGAAGGCGTTCCCAAAACCGAAGGTGCTTTA
  CAGATCTCCGCTGCCCCGGAGCCCGCCGCTGCGCCCGGCAGGACCATCGTGGCAGCGGGCTCCGTGGAAG
  AGGCGGTAATTCTGCCATTCCGCATCCCCCCTCCCCCTCTGGCGTCCGTGGACTTGGATGAGGACTTTCT
  TTTCACAGAACCATTGCCTCCTCCCCTGGAATTCGCCAATAGTTTTGATATCCCCGACGACCGGGCAGCT
  TCAGTTCCCGCTCTGGCTGACCTGGTCAAGCAGAAGAAAAGTGACACCCCTCAGCCCCCTTCGTTGAACT
  CCAGCCAACCAGCCAACTCTACAGACAGTAAGAAGCCAGCCGGCATCTCAAACTGTCTGCCCTCCTCATT
  CCTGCCACCCCCCGAAAGCTTTGACGCGGTCACCGACTCGGGGATCGAGGAGGTGGACAGCCGGAGTAGC
  AGCGACCACCACCTGGAGACAACCAGCACCATCTCCACAGTGTCCAGCATCTCCACGCTGTCTTCAGAGG
  GCGGGGAGAGCATGGATACTTGCACAGTCTATGCAGACGGGCAAGCCTTTGTGGTTGACAAGCCCCCAGT
  ACCTCCAAAGCCAAAAATGAAGCCCATCGTTCACAAAAGCAACGCACTTTACCAAGACACGCTCCCAGAA
  GAGGACACAGATGGCTTTGTGATCCCCCCACCTGCACCCCCGCCCCCGCCCGGCAGTGCCCAGGCCGGTG
  TGGCGAAGGTCATCCAGCCAAGGACCTCCAAGTTGTGGGGTGATGTTACAGAGGTCAAAAGCCCAATTCT
  CTCAGGCCCAAAGGCAAATGTCATTAGTGAGTTAAACTCCATTCTGCAGCAGATGAACAGGGGGAAATCG
  GTCAAGCCTGGGGAAGGGCTGGAGCTGCCCGTGGGAGCCAAGTCAGCTAACCTCGCTCCAAGAAGCCCGG
  AGGTCATGAGCACTGTCTCAGGTACACGGAGCACGACGGTCACCTTCACTGTCCGCCCCGGAACCTCCCA
  GCCCATCACCCTACAGAGCCGGCCCCCTGACTATGAAAGCAGGACCTCAGGACCGAGACGTGCCCCAAGC
  CCTGTGGTTTCGCCAACGGAATTGAGCAAAGAGATTCTGCCCACCCCTCCGTCTGCTGCAGCAGCCTCTC
  CCTCCCCCACACTCTCAGATGTCTTTAGCCTTCCAAGCCAGTCCCCTGCAGGGGACCTCTTTGGCTTGAA
  CCCAGCAGGACGCAGCAGGTCACCATCTCCTTCAATATTGCAACAGCCAATCTCAAATAAGCCTTTTACA
  ACTAAGCCTGTCCACCTGTGGACGAAACCAGATGTGGCAGACTGGCTGGAAAGTCTGAACTTGGGTGAAC
  ACAAGGAGACGTTCATGGACAATGAGATTGACGGCAGCCATCTGCCAAACCTCCAGAAGGAAGACTTGAT
  AGATCTTGGGGTGACTCGAGTTGGGCACAGGATGAACATAGAAAGGGCTTTGAAACAGCTGCTGGACAGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR200192 representing NM_133441
  Red=Cloning site Green=Tags(s)
  
  MKSLLNAFTKKEVPFREAPAYSNRRRRPPNTLAAPRVLLRSNSDNNLNAGAPEWAVCSAATSHRSLSPQL
  LQQTPSKPDGATKSLGSYAPGPRSRSPSLNRLGGAGEDGKRPQPPHWHVGSPFTPGANKDSLSTFEYPGP
  RRKLYSAVPGRLFVAIKPYQPQVDGEIPLHRGDRVKVLSIGEGGFWEGSARGHIGWFPAECVEEVQCKPR
  DSQAETRADRSKKLFRHYTVGSYDSFDAASDCIIEDKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPA
  FPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVVTVTRNLDPDDT
  ARKKAPPPPKRAPTTALTLRSKSMTAELEELVDKASVRKKKDKPEEIVPASKPSRTAENVAIESRVATIK
  QRPTSRCFPAASDVNSVYERQGIAVMTPTVPGSPKGPFLGLPRGTMRRQKSIDSRIFLSGITEEERQFLA
  PPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPPPSPTTYNCPRSPTPRVYGTIKPAFNQNPVAKVPPATRS
  DTVATMMREKGMFYRRELDRFSLDSEDVYSRSPAPQAAFRTKRGQMPENPYSEVGKIASKAVYVPAKPAR
  RKGMLVKQSNVEDSPEKTCSIPIPTIIVKEPSTSSSGKSSQGSSMEIDPQATEPGQLRPDDSLTVSSPFA
  AAIAGAVRDREKRLEARRNSPAFLSTDLGDEDVGLGPPAPRMQPSKFPEEGGFGDEDETEQPLLPTPGAA
  PRELENHFLGGGEAGAQGEAGGPLSSTSKAKGPESGPAAALKSSSPASPENYVHPLTGRLLDPSSPLALA
  LSARDRAMQESQQGHKGEAPKADLNKPLYIDTKMRPSVESGFPPVTRQNTRGPLRRQETENKYETDLSKD
  RRADDKKNMLINIVDTAQQKSAGLLMVHTVDIPVAGPPLEEEEDREDGDTKPDHSPSTVPEGVPKTEGAL
  QISAAPEPAAAPGRTIVAAGSVEEAVILPFRIPPPPLASVDLDEDFLFTEPLPPPLEFANSFDIPDDRAA
  SVPALADLVKQKKSDTPQPPSLNSSQPANSTDSKKPAGISNCLPSSFLPPPESFDAVTDSGIEEVDSRSS
  SDHHLETTSTISTVSSISTLSSEGGESMDTCTVYADGQAFVVDKPPVPPKPKMKPIVHKSNALYQDTLPE
  EDTDGFVIPPPAPPPPPGSAQAGVAKVIQPRTSKLWGDVTEVKSPILSGPKANVISELNSILQQMNRGKS
  VKPGEGLELPVGAKSANLAPRSPEVMSTVSGTRSTTVTFTVRPGTSQPITLQSRPPDYESRTSGPRRAPS
  PVVSPTELSKEILPTPPSAAAASPSPTLSDVFSLPSQSPAGDLFGLNPAGRSRSPSPSILQQPISNKPFT
  TKPVHLWTKPDVADWLESLNLGEHKETFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIERALKQLLDR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_133441
• ORF Size: 4410 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_133441.1, NP_597685.1
• RefSeq Size: 8182
• RefSeq ORF: 4413
• Locus ID: 171093
• MW: 158.3 kDa
• Gene Summary: binds to cortactin and alpha-latrotoxin receptor and is involved in the structural and functional organization of the post synaptic density [RGD, Feb 2006]