Txnrd2 (NM_022584) Rat Tagged ORF Clone
CAT#: RR207441
- TrueORF®
Txnrd2 (Myc-DDK-tagged ORF) - Rat thioredoxin reductase 2 (Txnrd2), nuclear gene encoding mitochondrial protein, (10 ug), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below)
"NM_022584" in other vectors (3)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Rat Tagged ORF Clone |
Symbol | Txnrd2 |
Synonyms | Tr3; Trxr2; Trxrd2 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RR207441 representing NM_022584
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGCGATTGTGGCGGCGCTGCGCGGATCCAGCGGGCGCTTCCGGCCGCAGACACGGGTTTTAACAC GCGGGACGCGGGGCGCGGCGGGCGCGGCGAGCGCAGCGGGAGGGCAGCAGAACTTTGATCTCTTGGTGAT CGGTGGGGGATCCGGTGGCCTAGCTTGTGCCAAGGAAGCGGCTCAGCTGGGAAGGAAGGTGGCTGTGGCT GACTATGTGGAACCCTCTCCCCGAGGCACCAAATGGGGCCTTGGTGGCACCTGTGTCAACGTGGGCTGCA TACCCAAGAAGCTGATGCATCAGGCCGCACTGCTGGGGGGCATGATCAGAGATGCTCAGCACTACGGCTG GGAGGTGGCCCAGCCTGTCCAGCACAACTGGAAGGCAATGGCCGAAGCCGTGCAAAACCATGTGAAGTCC TTGAACTGGGGTCATCGTGTCCAACTGCAGGACAGGAAAGTCAAGTACTTTAACATCAAAGCCAGCTTTG TCAACGAGCACACAGTTCACGGTGTCGACAAAGCCGGGAAGGTGACTCAGCTTTCAGCCAAGCACATAGT CATCGCTACAGGAGGACGGCCGAAGTACCCCACACAGGTCAAAGGAGCCCTGGAACACGGAATCACAAGT GATGACATCTTCTGGCTGAAGGAGTCCCCTGGGAAAACGTTGGTGGTTGGAGCCAGTTATGTGGCCCTGG AGTGTGCCGGCTTCCTCACTGGTATTGGCCTGGATACCACGGTCATGATGCGCAGCGTGCCCCTCCGAGG CTTTGACCAGCAAATGGCGTCTTTGGTCACAGAGCACATGGAGTCTCATGGCACCCGGTTCCTGAAAGGC TGTGTCCCCTCCCTCATCAGAAAACTCCCGACTAACCAACTGCAGGTCACTTGGGAGGATCTCGCTTCTG GCAAGGAGGACGTGGGCACCTTTGACACTGTCCTGTGGGCCATAGGGCGAGTTCCAGAGACCAGAAATTT GAATCTGGAGAAGGCTGGCGTTAATACCAACCCTAAGAATCAGAAGATCATTGTGGATGCCCAGGAGGCC ACCTCTGTCCCCCACATCTATGCCATTGGAGATGTTGCTGAGGGGCGGCCTGAGCTGACACCCACAGCTA TCAAGGCAGGAAAGCTTCTGGCTCAGCGGCTCTTTGGGAAATCCTCAACCTTAATGAATTACAGCAACGT CCCCACAACTGTCTTTACACCACTGGAGTATGGCTGTGTGGGACTGTCTGAGGAGGAGGCTGTGGCTCTC CACGGCCAGGAGCATATAGAGGTTTACCATGCATATTACAAGCCCCTAGAGTTCACAGTGGCAGATCGGG ATGCATCACAGTGCTACATAAAGATGGTATGCATGAGGGAGCCCCCACAACTGGTACTGGGCCTGCACTT CCTTGGCCCCAACGCTGGAGAAGTCACACAAGGATTTGCTCTTGGGATCCAGTGTGGGGCTTCATACGCA CAGGTGATGCAGACAGTAGGGATCCACCCCACCTGCTCTGAGGAGGTGGTTAAGCTGCACATCTCCAAGC GCTCTGGCCTGGATCCTACTGTGACTGGCTGCTGAGGT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RR207441 representing NM_022584
Red=Cloning site Green=Tags(s) MAAIVAALRGSSGRFRPQTRVLTRGTRGAAGAASAAGGQQNFDLLVIGGGSGGLACAKEAAQLGRKVAVA DYVEPSPRGTKWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAQHYGWEVAQPVQHNWKAMAEAVQNHVKS LNWGHRVQLQDRKVKYFNIKASFVNEHTVHGVDKAGKVTQLSAKHIVIATGGRPKYPTQVKGALEHGITS DDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSVPLRGFDQQMASLVTEHMESHGTRFLKG CVPSLIRKLPTNQLQVTWEDLASGKEDVGTFDTVLWAIGRVPETRNLNLEKAGVNTNPKNQKIIVDAQEA TSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMNYSNVPTTVFTPLEYGCVGLSEEEAVAL HGQEHIEVYHAYYKPLEFTVADRDASQCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIQCGASYA QVMQTVGIHPTCSEEVVKLHISKRSGLDPTVTGC*G TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_022584 |
ORF Size | 1578 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info The expression of this clone is not guaranteed due to the nature of selenoproteins. |
OTI Annotation | This clone encodes a selenoprotein containing the rare amino acid selenocysteine (Sec). Sec is encoded by UGA codon, which normally signals translational termination. Expression of this clone is not guaranteed due to the nature of selenoproteins. |
Reference Data | |
RefSeq | NM_022584.1, NM_022584.2, NM_022584.3, NP_072106.1 |
RefSeq Size | 2011 |
RefSeq ORF | 1581 |
Locus ID | 50551 |
MW | 56.5 kDa |
Gene Summary | The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jun 2017] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RN207441 | Txnrd2 (untagged ORF) - Rat thioredoxin reductase 2 (Txnrd2), nuclear gene encoding mitochondrial protein, (Note, selenocysteine protein, internal stop codon, see reference data summary) |
USD 710.00 |
|
RR207441L3 | Lenti ORF clone of Txnrd2 (Myc-DDK-tagged ORF) - Rat thioredoxin reductase 2 (Txnrd2), nuclear gene encoding mitochondrial protein, (10 ug), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below) |
USD 910.00 |
|
RR207441L4 | Lenti ORF clone of Txnrd2 (mGFP-tagged ORF) - Rat thioredoxin reductase 2 (Txnrd2), nuclear gene encoding mitochondrial protein, (10 ug), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below) |
USD 1,000.00 |
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