Adnp (NM_022681) Rat Tagged ORF Clone

CAT#: RR208071

Adnp (Myc-DDK-tagged ORF) - Rat activity-dependent neuroprotector homeobox (Adnp), (10 ug)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Adnp
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR208071 representing NM_022681
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTTCCAACTTCCTGTCAACAATCTTGGCAGTTTAAGAAAAGCCCGGAAAACTGTGAAAAAAATACTTA
  GTGACATTGGGTTGGAATACTGTAAAGAACATATAGAAGATTTTAAACAGTTTGAACCTAATGACTTTTA
  TTTGAAAAACACTACATGGGAGGATGTAGGACTGTGGGACCCTTCTCTTACAAAAAATCAGGACTATCGG
  ACAAAACCTTTCTGCTGCAGTGCTTGTCCGTTTTCCTCAAAATTCTTCTCTGCCTACAAAAGTCATTTCC
  GGAATGTCCATAGTGAAGACTTTGAAAATAGGATTCTCCTTAACTGCCCTTACTGTACCTTCAATGCAGA
  TAAAAAGACTTTGGAAACACACATTAAAATATTTCATGCTCCAAACTCCAGCGCACCAAGTAGCAGCCTC
  AGCACTTTCAAAGATAAAAACAAAAACGATGGCCTTAAACCTAAGCAGGCTGACAATGTAGAGCAAGCCG
  TGTATTACTGCAAGAAGTGCACTTACCGAGACCCTCTCTATGAGATCGTCAGGAAGCACATCTACAGGGA
  ACATTTTCAACACGTGGCAGCACCCTACATAGCAAAGGCAGGAGAAAAATCACTCAATGGTGCAGTCTCT
  CTGGGCACAAATGCCCGAGAAGAGTGTAACATCCACTGCAAGCGATGCCTTTTCATGCCCAAATCCTATG
  AAGCTTTGGTACAGCATGTCATTGAAGACCATGAACGGATAGGCTATCAGGTCACTGCCATGATTGGACA
  CACAAATGTTGTAGTTCCCCGAGCCAAACCCTTAATGCTAATTGCTCCCAAACCTCAAGAAAAAAAGAGC
  ATGGGACTCCCACCAAGAATCAGTTCTCTTGCTTCTGGAAATGTCCGGTCTTTGCCATCACAGCAGATGG
  TGAACCGATTGTCAATACCAAAGCCCAATTTAAATTCAACGGGAGTCAACATGATGTCCAATGTTCACCT
  GCAGCAAAACAACTATGGAGTGAAATCTGTGGGCCAGAGCTATGGTGTTGGCCAGTCAGTGAGGCTGGGG
  CTAGGTGGCAATGCTCCAGTTTCCATCCCTCAACAGTCTCAGTCTGTCAAACAGTTACTTCCAAGTGGAA
  ATGGGAGGTCCTACGGGCTAGGTGCTGAGCAGAGGCCCCCGGCAGCTGCCAGGTATTCCCTGCAGACTGC
  CAACACGTCCTCTCTACCCCCAGGCCAGGTAAAGTCTCCCTCTGTGTCTCAGTCACAGGCATCTAGAGTA
  TTAGGTCAGTCCAGTTCTAAACCTCCACCAGCAGCCACAGGCCCTCCTCCAAGCAACCATTGTGCCACTC
  AGAAGTGGAAAATATGTACAATCTGTAATGAGCTTTTTCCTGAGAATGTCTACAGTGTTCACTTCGAAAA
  GGAACATAAAGCGGAGAAAGTTCCAGCAGTAGCTAACTACATTATGAAAATACACAATTTTACTAGCAAA
  TGCCTCTATTGTAATCGCTATCTGCCCACAGATACCCTGCTCAACCATATGTTAATTCATGGTCTGTCTT
  GTCCATATTGCCGTTCCACCTTCAATGATGTGGAGAAGATGGCAGCACACATGCGAATGGTTCATATTGA
  TGAGGAGATGGGGCCTAAAACGGATTCTACCTTGAGCTTTGATTTGACATTGCAACAGGGCAGTCACACC
  AACATTCATCTCCTGGTGACCACATACAACCTGAGAGATGCCCCGGCTGAATCAGTTGCTTACCATGCCC
  AAAATAATGCCCCAGTTCCTCCAAAGCCACAACCAAAAGTTCAGGAAAAAGCTGATGTCCCTGTTAAAAG
  TTCACCTCAAGCTGCAGTGCCCTATAAAAAAGATGTGGGGAAGACCCTCTGCCCTCTCTGCTTTTCAATC
  CTAAAAGGACCCATATCTGATGCACTTGCACATCATTTACGAGAAAGACACCAAGTTATTCAGACAGTTC
  ATCCGGTTGAGAAAAAGCTAACTTACAAATGTATCCATTGCCTTGGTGTGTATACTAGCAACATGACAGC
  CTCAACCATCACTCTGCATCTAGTCCACTGCAGGGGTGTTGGAAAGACCCAGAATGGCCAGGACAAGACA
  AACGCACCTTCTCGGCTCAATCAGTCTCCAGGCCTGGCCCCTGTGAAGCGCACATATGAGCAAATGGAGT
  TTCCACTGCTAAAGAAGCGAAAGCTGGAGGATGAGAATGACTCCCCAGGCTGCTTTGAAGAGAAGCCGGA
  AGAGCCTGTTGTTTTAGCTTTAGACCCCAAGGGTCATGAAGATGATTCATATGAAGCTAGGAAAAGCTTT
  CTCACAAAGTACTTCAACAAACAGCCCTATCCCACTAGGAGAGAAATTGAGAAGTTAGCTGCCAGTCTGT
  GGCTGTGGAAGAGCGACATTGCCTCCCATTTCAGTAACAAGAGGAAGAAGTGTGTCCGTGACTGTGAGAA
  GTATAAGCCTGGTGTGCTGCTAGGTTTTAACATGAAAGAATTAAATAAAGTCAAACATGAGATGGATTTT
  GATGCTGAGTGGCTATTTGAAAATCATGACGAGAAAGCCTCAAGAGTCAATGCTAGCAAGACTGTTGACA
  AAAAGCTTAACCTTGGGAAAGAAGATGACAGCTTCTCAGATAGTTTTGAACATTTGGAAGAAGAATCCAA
  TGGAAGCGGCGGCCCTTTTGACCCTGTCTTTGAAGTTGAGCCTAAAATTCCCAGTGATAATGCAGAGGAG
  CCTGTGCCGAAGGTAATTCCTGAAGGTGCTTTGGAGTCTGAGAAGCTAGACCAAAAAGAGGAGGAGGATG
  GTTCAAAATATGAAACCATCCATTTGACTGAGGAACGAGCCAAACTGATGCATGATGCCTCTGATAGTGA
  GGTAGACCAAGATGATGTGGTTGAGTGGAAAGATGGTGCTTCGCCATCTGAGAGTGGGCCTGGTTCCCGA
  CAGGTCTCAGACTTTGAGGATAATACATGTGAAATGAAACCAGGAACCTGGTCTGATGAGTCTTCCCAGA
  GTGAAGACGCAAGGAGCAGTAAGCCGGCTGCCAAAAAAAAGGCTACAGTGCAAGATGACACAGAGCAGTT
  GAAATGGAAGAATAGTTCCTATGGAAAAGTTGAAGGGTTTTGGTCCAAGGACCAGTCACAGTGGGAAAAT
  GCATCTGAGAATGCAGAGCGCTTACCAAACCCACAGATTGAGTGGCAGAATAGCACAATTGACAGTGAGG
  ATGGGGAGCAGTTTGACAGCATGACCGATGGAGTTGCCGATCCCATGCACGGCAGCTTAACTGGAGTGAA
  GCTGAGCAGCCAGCAAGCC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR208071 representing NM_022681
  Red=Cloning site Green=Tags(s)
  
  MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYR
  TKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNSSAPSSSL
  STFKDKNKNDGLKPKQADNVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYIAKAGEKSLNGAVS
  LGTNAREECNIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRAKPLMLIAPKPQEKKS
  MGLPPRISSLASGNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSNVHLQQNNYGVKSVGQSYGVGQSVRLG
  LGGNAPVSIPQQSQSVKQLLPSGNGRSYGLGAEQRPPAAARYSLQTANTSSLPPGQVKSPSVSQSQASRV
  LGQSSSKPPPAATGPPPSNHCATQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSK
  CLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQQGSHT
  NIHLLVTTYNLRDAPAESVAYHAQNNAPVPPKPQPKVQEKADVPVKSSPQAAVPYKKDVGKTLCPLCFSI
  LKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKT
  NAPSRLNQSPGLAPVKRTYEQMEFPLLKKRKLEDENDSPGCFEEKPEEPVVLALDPKGHEDDSYEARKSF
  LTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDF
  DAEWLFENHDEKASRVNASKTVDKKLNLGKEDDSFSDSFEHLEEESNGSGGPFDPVFEVEPKIPSDNAEE
  PVPKVIPEGALESEKLDQKEEEDGSKYETIHLTEERAKLMHDASDSEVDQDDVVEWKDGASPSESGPGSR
  QVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATVQDDTEQLKWKNSSYGKVEGFWSKDQSQWEN
  ASENAERLPNPQIEWQNSTIDSEDGEQFDSMTDGVADPMHGSLTGVKLSSQQA
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_022681
• ORF Size: 3309 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_022681.2, NP_073172.2
• RefSeq Size: 5608
• RefSeq ORF: 3312
• Locus ID: 64622
• MW: 123.6 kDa
• Gene Summary: This gene encodes a member of a protein family characterized by nine zinc finger motifs followed by a homeobox domain. In vitro studies demonstrate that the encoded protein interacts with the brahma-related gene1-associated or hBRM factors (BAF) gene expression regulating complex, components of the protein translation machinery, and microtubule-associated proteins. This gene has been implicated in neuroprotection through various processes that include chromatin remodeling, splicing, cytoskeletal reorganization, and autophagy. Homozygous mutant knockout mice display embryonic lethality with defects in neural tube closure. [provided by RefSeq, Nov 2016]