SPATA18 (NM_145263) Human Untagged Clone

CAT#: SC100139

SPATA18 (untagged)-Human spermatogenesis associated 18 homolog (rat) (SPATA18)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SPATA18
• Synonyms: Mieap; SPETEX1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_145263, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGAAAACCTGAAAAGACTGGTCTCAAACGAAACTTTACGAACGTTGCAGGAAAAGCTAGACTTCT
  GGCTGAAGGAGTACAACACAAACACGTGTGATCAAAATCTAAACCATTGCCTTGAACTCATTGAGCAAGT
  TGCCAAGGTGCAGGGACAACTCTTTGGGATCCTCACAGCAGCAGCCCAAGAAGGAGGACGTAATGATGGT
  GTGGAAACAATCAAGTCACGCCTTTTGCCTTGGCTGGAGGCTTCCTTTACTGCTGCTTCCCTGGGAAAAT
  CTGTTGACAGCAAGGTCCCCTCTCTGCAGGACACGTTTGATAGGGAGAGACATAAAGATCCCAGTCCTCG
  GGATCGGGATATGCAACAGTTAGACTCTAATTTGAACTCAACCCGGAGTCAATGCAACCAGGTTCAAGAC
  GATCTGGTTGAAACTGAAAAGAATCTTGAAGAAAGCAAGAACAGATCGGCCATATCCCTTTTGGCTGCAG
  AGGAGGAAATAAATCAGCTGAAAAAGCAGCTTAAATCTCTTCAAGCTCAGGAGGATGCCCGCCACAGAAA
  CACAGATCAGAGGAGCTCAGAGAATAGGCGGTCAGAGCCTTGGAGCTTGGAGGAGCGGAAGCGTGAGCAG
  TGGAACTCACTCAAGCAGAATGCAGACCAGCAGGACACAGAAGCCATGTCCGATTATAAGAAACAGCTCC
  GAAACCTGAAGGAGGAGATAGCTGTTCTGTCTGCTGAGAAAAGTGCACTCCAAGGAAGGTCCTCCAGGAG
  CCGGTCTCCCAGCCCTGCCCCTCGCAGCCGTAGCTGCAGCCGCAGCAGATCTGCCAGCCCCTCCACCGCT
  GTCAAGGTCAGGAGACCGTCCCCAAACCGCTCCAAGCTGTCCAATGTGGCGCGCAAGGCTGCCCTCTTGT
  CCCGGTTCAGCGATTCCTATTCCCAGGCCCGCCTGGACGCGCAGTGCCTGCTGCGGCGCTGCATCGACAA
  GGCTGAGACCGTTCAGCGGATCATCTACATCGCCACAGTGGAGGCATTCCATGTAGCAAAAATGGCATTC
  AGACACTTCAAGATCCATGTGAGAAAATCGTTGACACCATCTTATGTGGGGTCGAATGACTTTGAGAATG
  CTGTCTTGGATTATGTCATTTGTCATCTTGATCTATATGATTCTCAAAGCAGTGTCAATGATGTGATCCG
  AGCCATGAATGTCAATCCCAAGATTTCATTCCCTCCTGTCGTTGACTTTTGCCTTCTCAGTGACTTCATC
  CAGGAGATATGTTGCATTGCCTTTGCAATGCAGGCCTTAGAACCACCCCTAGATATTGCATATGGAGCAG
  ATGGAGAAGTTTTTAATGATTGCAAATACCGCCGCAGCTACGACTCGGATTTCACTGCTCCCTTAGTCCT
  CTATCACGTGTGGCCTGCTCTCATGGAGAATGACTGTGTCATTATGAAGGGAGAAGCTGTCACCAGGAGA
  GGGGCTTTTTGGAATTCGGTGCGATCTGTAAGTCGTTGTCGAAGCAGGAGTTTAAGTCCCATTTGCCCCC
  GTAGCCAAATTGGTTTAAACACGATGTCTCGAAGTCGGAGTCCTTCTCCAATAAGATGTGGATTGCCAAG
  ATTTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_145263
• ORF Size: 1617 bp
• Insert Size: 4700
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_145263.3, NP_660306.1
• RefSeq Size: 4425
• RefSeq ORF: 1617
• Locus ID: 132671
• Gene Summary: This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]