PACRG (NM_152410) Human Untagged Clone

CAT#: SC100379

PACRG (untagged)-Human PARK2 co-regulated (PACRG), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PACRG
• Synonyms: GLUP; HAK005771; PACRG2.1; PARK2CRG
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_152410, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTGGCAGAAAAAGAGACCCTGAGCTTAAACAAATGCCCAGACAAGATGCCGAAGAGGACCAAGCTGC
  TGGCACAACAGCCGCTCCCGGTGCACCAGCCTCACTCTCTGGTTTCTGAGGGTTTCACAGTCAAAGCCAT
  GATGAAAAACTCAGTCGTGAGAGGCCCTCCAGCTGCAGGGGCATTTAAAGAAAGACCAACCAAGCCCACA
  GCATTTCGAAAATTCTATGAGCGAGGTGACTTCCCAATTGCCCTTGAGCATGATTCGAAAGGAAACAAAA
  TCGCCTGGAAGGTAGAAATTGAGAAGCTGGATTACCATCATTATCTGCCTCTGTTTTTTGATGGGCTTTG
  TGAAATGACATTTCCCTATGAGTTTTTTGCTCGGCAAGGAATCCACGACATGCTGGAACACGGTGGGAAC
  AAGATCCTACCTGTCCTTCCACAGCTCATTATCCCGATAAAAAATGCCTTGAACCTCCGAAACCGACAGG
  TCATCTGTGTCACTCTCAAGGTCCTCCAGCATCTGGTTGTGTCAGCTGAGATGGTGGGCAAGGCCTTGGT
  GCCTTATTACCGTCAAATCCTCCCTGTCCTGAACATCTTTAAGAATATGAATGGGTCTTACTCTTTGCCC
  AGGCTGGAGTGCAGTGGCGCGATCATGGCTCGTTGCAACCTCGACCACCTGGGCTCAAGTGATCCTCCCA
  CCTCAGCCTCTCAAGTAGCTGAGATTATAGTGAACTCCGGAGACGGCATTGACTACAGCCAGCAGAAGAG
  GGAGAACATTGGGGACTTGATCCAGGAGACACTGGAGGCCTTCGAGCGCTACGGAGGAGAAAATGCCTTT
  ATCAACATTAAGTACGTGGTCCCAACCTACGAGTCTTGCTTGCTAAACTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152410 unedited
  ACTCGGCACGNAGGCCTTGGTTGCAGCCTCTAGCCAAGGTCCTGCCCTCTTCCCGCCCCG
  CCCCTAGGGTCCAGCTCCCTTCACCTAGGAGCTGCCAAACATCTGGATCAACCTGGGCAC
  TACGAGGGGTTGAATTTCTACCATTATCGCGCCTTTTGATATTTTTTTCCAGACCTCCTG
  CTCACATCCGTAAAGCCCACTGATTCTTTTACTACACTTTTTATGAGAACAAGACATTTT
  CTAGGAAGATGGTGGCAGAAAAAGAGACCCTGAGCTTAAACAAATGCCCAGACAAGATGC
  CGAAGAGGACCAAGCTGCTGGCACAACAGCCGCTCCCGGTGCACCAGCCTCACTCTCTGG
  TTTCTGAGGGTTTCACAGTCAAAGCCATGATGAAAAACTCAGTCGTGAGAGGCCCTCCAG
  CTGCAGGGGCATTTAAAGAAAGACCAACCAAGCCCACAGCATTTCGAAAATTCTATGAGC
  GAGGTGACTTCCCAATTGCCCTTGAGCATGATTCGAAAGGAAACAAAATCGCCTGGAAGG
  TAGAAATTGAGAAGCTGGATTACCATCATTATCTGCCTCTGTTTTTTGATGGGCTTTGTG
  AAATGACATTTCCCTATGAGTTTTTTGCTCGGCAAGGAATCCACGACATGCTGGAACACG
  GTGGGAACAAGATCCTACCTGTCCTTCCACAGCTCATTATCCCGATNAAAATGCCTTGAA
  CCTCCGAAACCGACAGGTCATCTGTGTCACTCTCAAGGTCCTCCAGCATCTGGNTTGTGT
  CAGCTGAGATGGTGGGCAAGGCCTTNGTGCCTTATTACCGTCAAATCCCTCCTGTNCCTG
  ACATCTTTAAGATATGAATGTGAACTCCNGAGACNGCATTGACTACAGCCAGCAGAAGAG
  G
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_152410 unedited
  NNNAAATCACTGTGNACCGCGGCCCGCTTNCTAGNGATCGGTTTTTTTTTTTTTTTTTTG
  CATATGAAAATTATAGTTTATTGTCTATACAACTGAAGGTTTAACTCGGACTCCTGCTTC
  TGTCGGAGCTGTATAAAGAAGCAATTCTTCTCTTAGAACAAATAAGCACAGTACACTATT
  GTAATCTAAGAAACAGACACTATTTATGTATTGGAAAGCCTTGCTCTCAATAGGGCTAAC
  AGTCCAATGGCCCATAAGCCACTATTTTAGCAGCTGTAGAAAAGAAAGCTGTGGAAGTCA
  CAAGGAATGAGATGCTAAAAGCAACAGAGACAGATGATCCCAACACCAACGGGAGGTTTC
  AAGTCCCAGCTGCTGCCACTGTTAGTTTAGCAAGCAAGACTCGTAGGTTGGGACCACGTA
  CTTAATGTTGATAAAGGCATTTTCTCCTCCGTAGCGCTCGAAGGCCTCCAGTGTCTCCTG
  GATCAAGTCCCCAATGTTCTCCCTCTTCTGCTGGCTGTAGTCAATGCCGTCTCCGGAGTT
  CACATTCATATTCTTAAAGATGTTCAGGACAGGGAGGATTTGACGGTAATAAGGCACCAA
  GGCCTTGCCCACCATCTCAGCTGACACAACCAGATGCTGGAGGACCTTGAGAGTGACACA
  GATGACCTGTCGGTTTCGGAGGTTCAAGGCATTTTTTATCGGGATAATGAGCTGTGGAAG
  GACAGGTAGGATCTTGTTCCCACCGTGTTCCAGCATGTCGTGGATTCCTTGCCGAGCAAA
  AACTCATAGGGAATGTCATTTCCAAAGCCCTCAAAAAACAGAGCGGAAATGATGGTTATC
  CAGCTTCTCATTTCTACTTCCAGGCGATTTTGTTTCTTTCAATATGCTCAAGGCATA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_152410
• ORF Size: 891 bp
• Insert Size: 1400
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_152410.1, NP_689623.1
• RefSeq Size: 1619
• RefSeq ORF: 891
• Locus ID: 135138
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).