Nesprin 1 (SYNE1) (NM_133650) Human Untagged Clone

CAT#: SC100551

SYNE1 (untagged)-Human spectrin repeat containing, nuclear envelope 1 (SYNE1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SYNE1
• Synonyms: 8B; ARCA1; C6orf98; CPG2; dJ45H2.2; DKFZp781J13156; EDMD4; FLJ30878; FLJ41140; KIAA0796
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_133650, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGAGAACGACTTGCTAAAGCCAGCCATGAAAGCAAAGCATCTGAGATTGAATACAAGCTGGGAAAGG
  TCAACGACCGGTGGCAGCATCTCCTGGACCTCATTGCAGCCAGGGTGAAGAAGCTGAAGGAGACCCTGGT
  AGCCGTGCAGCAGCTTGATAAGAACATGAGCAGCCTGAGGACCTGGCTCGCTCACATCGAGTCAGAGCTG
  GCCAAGCCAATAGTCTACGATTCCTGTAACTCGGAAGAAATACAGAGAAAGCTTAATGAGCAGCAGGAGC
  TTCAGAGAGACATAGAGAAGCACAGTACAGGTGTTGCATCTGTCCTCAACCTGTGTGAAGTCCTGCTGCA
  CGACTGTGACGCCTGTGCCACTGATGCCGAGTGTGACTCTATACAGCAGGCTACGAGAAACCTGGACCGG
  CGGTGGAGAAACATTTGTGCTATGTCCATGGAAAGGAGGCTGAAAATCGAAGAGACGTGGCGATTGTGGC
  AGAAATTTCTGGATGACTATTCACGTTTTGAAGATTGGCTGAAGTCTTCAGAAAGGACAGCTGCTTTTCC
  CAGCTCTTCTGGGGTGATCTATACAGTTGCCAAGGAAGAACTAAAGAAATTTGAGGCTTTCCAGCGACAG
  GTCCACGAGTGCCTGACGCAGCTGGAACTGATCAACAAGCAGTACCGCCGCCTGGCCAGGGAGAACCGCA
  CTGATTCAGCATGTAGCCTCAAACAGATGGTTCACGAAGGCAACCAGAGATGGGACAACCTGCAAAAGCG
  TGTCACCTCCATCTTGCGCAGACTCAAGCATTTTATTGGCCAGCGTGAGGAGTTTGAGACTGCGCGGGAC
  AGCATTCTGGTCTGGCTCACAGAGATGGATCTGCAGCTCACTAATATTGAACATTTTTCTGAGTGTGATG
  TTCAAGCTAAAATAAAGCAACTCAAGGCCTTCCAGCAGGAAATTTCACTGAACCACAATAAGATTGAGCA
  GATAATTGCCCAAGGAGAACAGCTGATAGAAAAGAGTGAGCCCTTGGATGCAGCGATCATCGAGGAGGAA
  CTAGATGAGCTCCGACGGTACTGCCAGGAGGTCTTCGGGCGTGTGGAAAGATACCATAAGAAACTGATCC
  GCCTGCCTCTCCCAGACGATGAGCACGACCTCTCAGACAGGGAGCTGGAGCTGGAAGACTCTGCAGCTCT
  GTCGGACCTGCACTGGCACGACCGCTCTGCAGACAGCCTGCTTTCTCCACAGCCTTCCTCCAATCTCTCC
  CTCTCGCTCGCTCAGCCCCTCCGGAGCGAGCGGTCAGGACGAGACACCCCGGCTAGTGTGGACTCCATCC
  CCCTGGAGTGGGATCACGACTATGACCTCAGTCGGGACCTGGAGTCTGCAATGTCCAGAGCTCTGCCCTC
  TGAGGATGAAGAAGGTCAGGATGACAAAGATTTCTACCTCCGGGGAGCTGTTGGCTTATCAGATGTAATG
  ATCCCCGAAAGCCCTGAGGCCTATGTAAAACTCACAGAAAATGCAATCAAAAATACCTCCGGGGACCACA
  GTGCCCTAGAGTCACAGATCCGACAACTGGGCAAAGCCCTGGATGATAGCCGTTTTCAGATACAGCAAAC
  CGAAAATATCATTCGCAGCAAAACTCCCACGGGGCCGGAGCTAGACACCAGCTACAAAGGCTACATGAAA
  CTGCTGGGCGAATGCAGTAGCAGTATAGACTCCGTGAAGAGACTGGAGCACAAACTGAAGGAGGAAGAGG
  AGAGCCTTCCTGGCTTTGTTAACCTGCATAGTACCGAAACCCAAACGGCTGGTGTGATTGACCGATGGGA
  GCTTCTCCAGGCCCAGGCATTGAGCAAGGAGTTGAGGATGAAGCAGAACCTCCAGAAGTGGCAGCAGTTT
  AACTCAGACTTGAACAGCATCTGGGCCTGGCTGGGGGACACGGAGGAGGAGTTGGAACAGCTCCAGCGTC
  TGGAACTCAGCACTGACATCCAGACCATCGAGCTCCAGATCAAAAAGCTCAAGGAGCTCCAGAAAGCTGT
  GGACCACCGCAAAGCCATCATCCTCTCCATCAATCTCTGCAGCCCTGAGTTCACCCAGGCTGACAGCAAG
  GAGAGCCGGGACCTGCAGGATCGCTTGTCGCAGATGAATGGGCGCTGGGACCGAGTGTGCTCTCTGCTGG
  AGGAGTGGCGGGGCCTGCTGCAGGATGCCCTGATGCAGTGCCAGGGTTTCCATGAAATGAGCCATGGTTT
  GCTTCTTATGCTGGAGAACATTGACAGAAGGAAAAATGAAATTGTCCCTATTGATTCTAACCTTGATGCA
  GAGATACTTCAGGACCATCACAAACAGCTTATGCAAATAAAGCATGAGCTGTTGGAATCCCAACTCAGAG
  TAGCCTCTTTGCAAGACATGTCTTGCCAACTACTGGTGAATGCTGAAGGAACAGACTGTTTAGAAGCCAA
  AGAAAAAGTCCATGTTATTGGAAATCGGCTCAAACTTCTCTTGAAGGAGGTCAGTCGTCATATCAAGGAA
  CTGGAGAAGTTATTAGACGTGTCAAGTAGTCAGCAGGATTTGTCTTCCTGGTCTTCTGCTGATGAACTGG
  ACACCTCAGGGTCTGTGAGTCCCACATCAGGAAGGAGCACCCCAAACAGACAGAAAACGCCACGAGGCAA
  GTGTAGTCTCTCACAGCCTGGACCCTCTGTCAGCAGTCCACATAGCAGGTCCACAAAAGGTGGCTCCGAT
  TCCTCCCTTTCTGAGCCAGGGCCAGGTCGGTCCGGCCGCGGCTTCCTGTTCAGAGTCCTCCGAGCAGCTC
  TTCCCCTTCAGCTTCTCCTGCTCCTCCTCATCGGGCTTGCCTGCCTTGTACCAATGTCAGAGGAAGACTA
  CAGCTGTGCCCTCTCCAACAACTTTGCCCGGTCATTCCACCCCATGCTCAGATACACGAATGGCCCTCCT
  CCACTCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_133650 unedited
  TATTTTGTAATACGACTCACTATAGGGCGGCCGCGAAATTCGCACGAGGAACAAATGGGA
  GAACGACTTGCTAAAGCCAGCCATGAAAGCAAAGCATCTGAGATTGAATACAAGCTGGGA
  AAGGTCAACGACCGGTGGCAGCATCTCCTGGACCTCATTGCAGCCAGGGTGAAGAAGCTG
  AAGGAGACCCTGGTAGCCGTGCAGCAGCTTGATAAGAACATGAGCAGCCTGAGGACCTGG
  CTCGCTCACATCGAGTCAGAGCTGGCCAAGCCAATAGTCTACGATTCCTGTAACTCGGAA
  GAAATACAGAGAAAGCTTAATGAGCAGCAGGAGCTTCAGAGAGACATAGAGAAGCACAGT
  ACAGGTGTTGCATCTGTCCTCAACCTGTGTGAAGTCCTGCTGCACGACTGTGACGCCTGT
  GCCACTGATGCCGAGTGTGACTCTATACAGCAGGCTACGAGAAACCTGGACCGGCGGTGG
  AGAAACATTTGTGCTATGTCCATGGAAAGGAGGCTGAAAATCGAAGAGACGTGGCGATTG
  TGGCAGAAATTTCTGGATGACTATTCACGTTTTGAAGATTGGCTGAAGTCTTCAGAAAGG
  ACAGCTGCTTTTCCCAGCTCTTCTGGGGTGATCTATACAGTTGCCAAGGAAGAACTAAAG
  AAATTTGAGGCTTTCCAGCGACAGGTCCACGAGTGCCTGACGCAGCTGGAACTGATCAAC
  AAGCAGTACCGCCGNCTGGCCAGNGAGAACCGCACTGATTCAGCAATTAGCCTCAAACAG
  ATGGTTCACGAAGGCAACCAGAGATGGGACAACCTGCANAAGCGTGTCACCTCCATCTTG
  CGCAGACTCAAGGNTNTTGCTATGCCTCATCTGTAAATTANAGCCANNAGATGGGACTGG
  NCCATTTGATGCAGTCTTGAGACCAGTCTCANTGATTNTGTAGAATGGATGGGCAGAGAG
  TAAACCCGGATGATTAGCAAAGATGCCAGCTCTCATTGCTGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_133650 unedited
  TATGAACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTATAATATCTATA
  ATAAATGCAAAGAAATCAATACAAACAAAACTTGGCTTTAGCAAACTGTACATACATAAA
  TATCTTTTTTTTTACTATAACATTCAACTTTTTTCACATAAAGCCTTCCATGATCTTATT
  TATTACATCTAGTTTTTCTTTATACCTCTAAAAAAAAGTGCCTTTTAGATTTACAGCTTG
  TGCTTCTAAAGCAAAGGTTAAAACATCATGCCCCAAAGGAAAACAAGGTAAAAAGGAAGC
  TGCCATATAAGCTCTTAAAAATTGTATGTTACAAGGTTCTAAAATCTCTTCAGCACTGGT
  TGGTTGGTAGATTGTACGACACTGACATGGTGCTTGGGAGGGTCATTTATCTGATGGTTG
  GAGCAGCACCATGGGAAAGCTGCCCAGATGGTCTACTGAAGTCCTTGGCTGTGCACAGAA
  TGGGCCAAGGGCCCAGAATTCATGAGTCCGGGGAACTTTGGAGGTCCTTACTCAATCTCC
  TTAGTGCTAAGGTTCAGAGTCTCAAACCAGATTTCTTCCAAACCTTCTTGTTGTCTGTTT
  GTTCCCCCGTCACTGTTTATCTTCCACCTCTGAAGCCATAATTTGCACACATGTGATCTG
  GAGGAGGGCTAAAGCTGCCACACCGAGGGCTTTCGCCAAGATCAAGGTCCTCTTGTTGGT
  AGTTTGGGATTGCTTATGACCCGATCCTCCTTATGCTACCAGCACTTCTGCAGATGGCAT
  CTGCTTAGTTCAGAGTGGAGGAGGGCCATTCGTGTATCTGAGCATGGNGTGGAATGACCG
  GGCAAAGTTGTTGGAGAAGGCACAGCTGTAGTCTTCCTCTGACATTGTACAAGGCAGCAA
  GCCCGATGAGAGAGCCAGAAAGCTGAAGGGAAGAGCTGCTCGAGACTCTGACAGAACCGC
  GGCCGACGAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_133650
• ORF Size: 2949 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_133650.1, NP_598411.1
• RefSeq Size: 3801
• RefSeq ORF: 2949
• Locus ID: 23345
• Domains: spectrin
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) differs in the 5' UTR and lacks many exons in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 3, also known as nesprin-1 alpha) with a distinct N-terminus, compared to isoform 1.