DUSP18 (NM_152511) Human Untagged Clone

CAT#: SC101321

DUSP18 (untagged)-Human dual specificity phosphatase 18 (DUSP18)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DUSP18
• Synonyms: DSP18; DUSP20; LMWDSP20
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC101321 sequence for NM_152511 edited (data generated by NextGen Sequencing)
  ATGACAGCACCCTCGTGTGCCTTCCCAGTTCAGTTCCGGCAGCCCTCAGTCAGCGGCCTC
  TCGCAGATAACCAAAAGCCTGTATATCAGCAATGGTGTGGCCGCCAACAACAAGCTCATG
  CTGTCTAGCAACCAGATCACCATGGTCATCAATGTCTCAGTGGAGGTAGTGAACACCTTG
  TATGAGGATATCCAGTACATGCAGGTACCTGTGGCTGACTCCCCTAACTCACGTCTCTGT
  GACTTCTTTGACCCTATTGCTGACCATATCCACAGCGTGGAGATGAAGCAGGGCCGTACT
  TTGCTGCACTGTGCTGCTGGTGTGAGCCGCTCAGCTGCCCTGTGCCTCGCCTACCTCATG
  AAGTACCACGCCATGTCCCTGCTGGACGCCCACACGTGGACCAAGTCATGCCGGCCCATC
  ATCCGACCCAACAGCGGCTTTTGGGAGCAGCTCATCCACTATGAGTTCCAATTGTTTGGC
  AAGAACACTGTGCACATGGTCAGTTCCCCAGTGGGAATGATCCCTGACATCTATGAGAAG
  GAAGTCCGTTTGATGATTCCACTGTGA
  
  Clone variation with respect to NM_152511.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152511 unedited
  GGATTTTGTAATACGACTCACTATAGGGCGGCNCGCGAATCGGCACGAGGGTGCGACCCG
  GCCCGTTGCCGTAGAGATGGGCAGGGCTGGATGGAGTGGGGTGCGGTGAGCTGAGCTGAC
  CCTGCTTCGCCACGGGGACTGCAGTGACCCCGGCTTGCCGGCAGGGCGGGTAACAGGTTG
  AGCCAGGGTGGGGCTGCTCAGGGGCGTGGAGCCGAGGCCAGGATTTCTCTGAAGACCCGG
  CACAGGCTATTCCTTTCTGCGACGAGCCCATTGCTATGGAAACCAAAGCGTTAGGCCAGC
  GGGGATTGAGGCTGCGGGATCATGACGGGTCTCTCTCCCGAAGAACCTTGCCTAAGGCTT
  CCCCAAGCGGCTACTTCCTGAGCGAACCCGCCCACCCGCCTGAAGGAGAGAGTTTTCCAT
  GGACACAGCCTAGCAGAAAGACGCAGCCTTCGTGCTTCGCTGACTGCTGACCACTGACCC
  ACCGCCTTGATGACAGCACCCTCGTGTGCCTTCCCAGTTCAGTTCCGGCAGCCCTCAGTC
  AGCGGCCTCTCGCAGATAACCAAAAGCCTGTATATCAGCAATGGTGTGGCCGCCAACAAC
  AAGCTCATGCTGTCTAGCAACCAGATCACCATGGTCATCAATGTCTCAGTGGAGGTAGTG
  AACACCTTGTATGAGGATATCCAGTACATGCAGGTACCTGTGGCTGACTCCCCTAACTCA
  CGTCTCTGTGACTTCTTTGACCCTATTGCTGACCATATCCACAGCGTGGAGATGAAGCAN
  GGCCGTACTTTGCTGCACTGTGCTGCTGGTGTGAGCCGCTCAGCTGCCCTGTGCCTCGCC
  TACCTCATGAAGTACACGCCATGTCCCTGCTGGANCCCNCACGTGGACAAGTNATGCCNG
  NCCATCATNCGACCCACANNGNTTTTGGNAGCACTCATCCCTATGAGTCCATGNTGGCAG
  AAACTGTGCCATGTCAGTCCCAGGGGGAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_152511 unedited
  GAACTCTTGTACCGCGCCGCAATTTAGGATCGAGTTTTTTTTTTTTTTTTTTTTACACAC
  AGGGTAACTTTTTGGAAGAGTACTTTGTAACAATAAAGTGCTGTGCACAGAAAGGAGAAA
  TGCCATTATGAGGATGTGTGTGCCGACCTGGGACCAGCAGGGTGAAAGAGTCTATCATTC
  ATGATGAGAGCTGCCATTTGCGCTAAGCACACACCATGTGCCAGGCACTATGCCAAGAAA
  TTGTTGAATCTTCACAATAACTCTGTGAGAAAAGGGCTGTCATTGGACAGATGAGGACAC
  TGATGCTCCCAGGGGTCCACATCACATGAAGAGGAGGTGACAGGGCTGGGCCTTGGTCCG
  AAGCTCCAGCCTTCCAAGCCAAGGCCTGTGAGAGGAACCGCTGAAACCTGATGTTAGGCC
  TGTTTTTCTCATGTGCCCTGGAGAAAGGGACTAACACCATCTTTTGCCCAAGTTTGGTGA
  GGGATGGCCAAGAGCTCTTTGAAACTTTGCCATGTACAATAGCACTCACAATTTTTTTTT
  AATTTTTTATACAGTGGTATCGGGGTACAGTGGCTCATCAACACTTTGGGGAGGGCTGAG
  CCTGAAGATTTGCTTGAGCCCAGAGTTTGAGACCAGTCTGGGCGACATAGTTAAATCTCA
  TCTCTTTTAAAAAAGGAAAAAAATGAGGCGGCCATGGGTGGAAACATCTGTAGTCCCAGC
  CCCCCAGGAGCTTAGGAAGAAGATCACTTGAGCCTGAAAGGTTGTGGCTACCTGAGGCAT
  GATCACACTACTGCACCTCCAGATGGGTGAAGAACCAAGGAATTTTCAAAAAAGACAAAA
  AAAAATTCCCAGGGGAATGCCTTCTTAAAACATCTTATGCCTAAGTAAATCTAGAAAACG
  GAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_152511
• ORF Size: 567 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_152511.3, NP_689724.3
• RefSeq Size: 2453
• RefSeq ORF: 567
• Locus ID: 150290
• Domains: DSPc
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]). [supplied by OMIM, Dec 2009]
  Transcript Variant: This variant (2) lacks an exon in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.