Prickle (PRICKLE1) (NM_153026) Human Untagged Clone

CAT#: SC101342

PRICKLE1 (untagged)-Human prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PRICKLE1
• Synonyms: EPM1B; RILP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC101342 sequence for NM_153026 edited (data generated by NextGen Sequencing)
  ATGCCTTTGGAGATGGAGCCCAAGATGAGCAAACTGGCCTTTGGCTGTCAGAGAAGTTCC
  ACATCAGATGATGACTCTGGCTGTGCATTGGAGGAGTACGCCTGGGTCCCCCCGGGCCTG
  AGACCAGAGCAGATCCAGCTCTATTTTGCTTGCTTACCAGAGGAAAAAGTTCCTTACGTT
  AACAGCCCCGGAGAGAAGCATCGGATTAAACAGCTTTTGTACCAGTTACCACCACATGAT
  AATGAGGTACGGTATTGCCAGTCTTTGAGTGAAGAGGAGAAAAAAGAGTTGCAGGTGTTC
  AGTGCTCAGCGGAAGAAAGAAGCACTGGGAAGAGGAACAATTAAGCTTCTGTCCAGAGCA
  GTCATGCATGCTGTGTGTGAGCAGTGTGGTTTGAAGATAAATGGAGGTGAAGTTGCAGTG
  TTCGCCTCCCGTGCGGGCCCTGGTGTGTGCTGGCACCCATCCTGTTTTGTCTGTTTCACG
  TGTAATGAGCTGCTGGTCGACCTCATCTATTTTTATCAGGATGGAAAAATTCACTGTGGC
  AGGCACCATGCAGAACTGCTCAAACCACGGTGCTCAGCATGTGACGAGATAATTTTTGCT
  GATGAGTGCACAGAAGCTGAGGGTCGCCATTGGCACATGAAACACTTCTGCTGCCTTGAG
  TGTGAAACGGTCCTGGGAGGACAGAGGTATATCATGAAGGACGGCCGCCCCTTCTGCTGT
  GGCTGTTTTGAGTCTCTCTATGCGGAGTACTGTGAAACCTGTGGGGAACATATTGGTGTG
  GACCATGCACAGATGACCTATGACGGGCAGCACTGGCACGCCACGGAAGCCTGCTTTTCT
  TGTGCCCAGTGTAAAGCCTCTTTGTTGGGATGTCCCTTCCTTCCCAAACAGGGTCAGATT
  TACTGCTCAAAAACGTGCAGTCTTGGTGAAGACGTCCATGCCTCTGATTCTTCCGACTCT
  GCATTTCAGTCAGCTCGATCAAGAGACTCCCGAAGAAGTGTCCGAATGGGCAAGAGCAGC
  CGGTCAGCAGATCAGTGTAGACAGTCTCTCCTCTTATCGCCTGCTCTGAACTACAAGTTT
  CCTGGCCTCTCAGGCAATGCTGATGACACCCTTTCTCGAAAATTGGATGATCTGAGTCTC
  TCCAGACAAGGAACAAGTTTTGCCAGTGAAGAATTTTGGAAAGGCAGAGTAGAGCAGGAA
  ACTCCAGAAGACCCTGAAGAATGGGCTGATCATGAAGATTATATGACGCAGCTCCTCCTC
  AAGTTTGGTGATAAAAGCCTCTTTCAGCCACAGCCCAATGAGATGGATATTCGAGCCAGT
  GAGCACTGGATATCTGATAACATGGTTAAAAGTAAGACCGAGTTAAAGCAAAATAACCAG
  AGCCTTGCAAGTAAAAAATACCAGTCTGATATGTACTGGGCACAGTCACAAGATGGACTG
  GGCGATTCTGCTTATGGCAGCCACCCAGGCCCTGCAAGCAGTAGAAGGCTTCAGGAATTG
  GAACTGGACCATGGGGCTTCAGGGTATAATCATGATGAAACACAGTGGTATGAAGATTCC
  CTGGAGTGTCTGTCAGACCTGAAACCAGAGCAAAGTGTTCGGGATTCGATGGATTCTTTG
  GCATTGTCCAATATCACAGGGGCTTCGGTGGATGGAGAAAACAAGCCAAGGCCATCATTG
  TATTCTCTGCAAAATTTTGAGGAGATGGAAACAGAAGATTGTGAGAAGATGAGCAATATG
  GGAACTTTGAACTCTTCCATGCTGCACAGGAGTGCAGAGTCCTTAAAGAGTCTAAGTTCA
  GAGTTGTGTCCAGAGAAAATCCTGCCTGAAGAGAAGCCAGTACATCTGCCAGTGCTCAGA
  AGGTCCAAGTCTCAATCCAGACCCCAGCAGGTCAAGTTTTCTGATGATGTCATTGACAAT
  GGGAACTATGACATTGAAATCCGGCAGCCTCCGATGAGTGAAAGGACTCGGAGACGCGTC
  TACAATTTTGAAGAGAGGGGATCCAGGTCTCATCACCACCGCCGCCGGAGAAGTAGAAAG
  TCCCGCTCCGACAATGCCCTGAATCTTGTTACAGAAAGAAAATACTCTCCCAAGGACAGA
  CTGCGGCTGTACACCCCCGATAACTATGAGAAATTTATACAGAATAAAAGTGCCCGGGAG
  ATCCAAGCATACATCCAGAATGCTGATCTCTACGGACAGTACGCCCATGCCACTTCCGAT
  TATGGCCTGCAGAACCCAGGAATGAATCGGTTTCTGGGACTCTACGGCGAGGATGATGAT
  TCCTGGTGTTCTTCCTCCTCCTCCTCTTCCGACTCGGAAGAAGAAGGATATTTTCTTGGA
  CAACCAATCCCTCAACCCCGGCCACAGAGATTTGCCTACTATACAGATGACCTTTCTAGT
  CCACCATCTGCACTTCCCACCCCTCAGTTTGGTCAGAGGACAACAAAATCCAAGAAGAAA
  AAGGGACACAAGGGCAAAAATTGTATTATTTCTTAA
  
  Clone variation with respect to NM_153026.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_153026 unedited
  TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTGCGCTGCTCACCC
  TCGCCCACCCCTGACGCCGCGGACCGCAGCTCCTCAGCCCCGCAGCCCCGCAGCCCAGCA
  GCCCCGCAGCGGCGCCGAGGACAGTGCAGCCGAGTTGCGTCTCCCTCGCGCGAGCAGCCA
  TTGTTTGATGTCCTGTGACTGAGAAACCAGGCTTTAAACTTTATGCCTTTGGAGATGGAG
  CCCAAGATGAGCAAACTGGCCTTTGGCTGTCAGAGAAGTTCCACATCAGATGATGACTCT
  GGCTGTGCATTGGAGGAGTACGCCTGGGTCCCCCCGGGCCTGAGACCAGAGCAGATCCAG
  CTCTATTTTGCTTGCTTACCAGAGGAAAAAGTTCCTTACGTTAACAGCCCCGGAGAGAAG
  CATCGGATTAAACAGCTTTTGTACCAGTTACCACCACATGATAATGAGGTACGGTATTGC
  CAGTCTTTGAGTGAAGAGGAGAAAAAAGAGTTGCAGGTGTTCAGTGCTCAGCGGAAGAAA
  GAAGCACTGGGAAGAGGAACAATTAAGCTTCTGTCCAGAGCAGTCATGCATGCTGTGTGT
  GAGCAGTGTGGTTTGAAGATAAATGGAGGTGAAGTTGCAGTGTTCGCCTCCCGTGCGGGC
  CCTGGTGTGTGCTGGCACCCATCCTGTTTTGTCTGTTTCACGTGTAATGAGCTGCTGGTC
  GACCTCATCTATTTTTATCAGGATGGAAAAATTCACTGTGGCAGGCACCATTGCAGACTG
  CTCAAACCACGGTGCTCAGCATGTGACGAGATNNATTTTGCTGATGAGTGACAGAAGCTG
  AGGGTCGCCATTGCACATGAAAACTTCTGTGCCTTGAGNNGGAACGTCCTGGAGGNAAGA
  GTTTCATGNAAGACCGCCGCCTCTTTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_153026 unedited
  GTACTCTATGNACCGCGCCGCAATCTANGATCAGTTTTTTTTTTTTTTTTTTACTTGTTT
  TTACCATATATTCCAGGGGTTATGTGTGTGGAGGGGTTGTTTTTACATTTATACAGTTTA
  CATTGCTTGACCCATAAGTAACACTTGTAAGATTAATAGGGCCATAGTTTTAAAGAGTAC
  TTACATAGCCCCACCATGCATACAGAGCCTTTTTTAATATTGGAAAAAAAAATCAAAAAA
  AGTTGAATTTTCCATCACTAGGCAATGTAAATTTGACCATCTACATTTATAAACCCTGAC
  TAAAATATAAGCAATCAGTTCATCCATAAATTCTGGTTCCCTGGCAAATCTAGCACTGCA
  GCGTAACAAACGGCTTACAATTCAGGGATATAAAAATATCAGCTTTAAAATCTGAACTGT
  ACAGTATATACATTAATATTTGCACCGTTAAATTAGGAATACACTTAAGTCTATGAAATA
  CTAAGTTATAAATAGCAATGTTTTTTGTTTTTTTTTTCAATCTGTAGCTGGCGCTGATAC
  AATACAATGTTTACCTGGCCAAAGAGGGTTCGAGGGGACAAGCTGGCCTCACAATAAGAT
  GCACAGTGTTAGCTAGGTCATCGTGACAGGCATGCCTCACACCAAGACGGACTATCAAGA
  CCTGAGCCGACCTGACTTACATAAATGACAAACACTAGTGCTTTACAAAGGTGGCTGGAG
  TTCTCCATCTTCTAAAATCACATCCAATCCCCTTTAGTCAGCATCTTCAGTATTCCCTTG
  GAGACTGGAAAACCAAGGCGCTACGTCCATCTGTAACGCACCCGACCGGAAAGGCACAAG
  ATTGTCCGTCCCCCTGGCACCCTTCAAGAGGGGAAATTGGGGAAAACCAACCTTTAAAGG
  TTAATCCGACCCGGTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_153026
• ORF Size: 2496 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_153026.1, NP_694571.1
• RefSeq Size: 3293
• RefSeq ORF: 2496
• Locus ID: 144165
• Domains: LIM
• Protein Families: Druggable Genome
• Protein Pathways: Wnt signaling pathway
• Gene Summary: This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]
  Transcript Variant: This variant (1) represents the longest transcript. Variants 1-4 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.