Peroxiredoxin 2 (PRDX2) (AK022395) Human Untagged Clone

CAT#: SC101510

(untagged)-Human cDNA FLJ12333 fis, clone MAMMA1002198, highly similar to THIOREDOXIN PEROXIDASE 1


Reconstitution Protocol

USD 660.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PRDX2
Synonyms HEL-S-2a|NKEF-B|NKEFB|PRP|PRX2|PRXII|PTX1|TDPX1|TPX1|TSA
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for AK022395, the custom clone sequence may differ by one or more nucleotides


ACGTCTTGGTTCGGGCCGGGCATAAAAGGCTTCGCGGCCCAGGGCTCACTTGGCGCTGAGAACGCGGGTC
CACGCGTGTGATCGTCCGTGCGTCTAGCCTTTGCCCACGCAGGTATGAACACCCGGAGTGCACCTGGCGG
GAGGACCCCCTTCAGGCTGCTTTGGCCCGATCCTGACTTTAGTGCTGGCCGCCTTTGCTTTCCATCCGCT
ATAGTGGCCTCCTTTGTCCTTGCGGGGGAAACCGAGGCCACAGCCTTGCAGCGCAGTCCTGATCGCCCGA
CTTCCCGCCCCCTGCTCGTGCGGGCCTCACTGTCTCCTTCTGGGCTGGGGGCTTGCGACACCGCCCTCCG
GCCGACTCGCTCGTGGGGTGCTGGTGGCAGTGGCTGGGTCACTCGTGCTCTGGTCAGGAGAGCGGGTCTC
CGGCAGCCTCCGGGCCTCGTAGACCGGGTACCCGGGAGGGTGAGGGTTAGTGCTGTCGCCTCCGCCGTGC
TGACTCAGTCATAGGGCCCAGCACGCAGCGCGACCTTGGGTTGGGAGGACAAAGTGTCTTCCCGGGCGCA
CTGACCGGGCGGGGGTCTCAGCTTTCAGTCATGGCCTCCGGTAACGCGCGCATCGGAAAGCCAGCCCCTG
ACTTCAAGGCCACAGCGGTGGTTGATGGCGCCTTCAAAGAGGTGAAGCTGTCGGACTACAAAGGTGAGCG
CCGCCCGGAGGGGGCCCAGGTAGAAGCGGGGCCGTGCATGAGAGAAGCTGGGCCCTAACTCCTCTGTGTC
CCTCCTCCCCAGGGAAGTACGTGGTCCTCTTTTTCTACCCTCTGGACTTCACTTTTGTGTGCCCCACCGA
GATCATCGCGTTCAGCAACCGTGCAGAGGACTTCCGCAAGCTGGGCTGTGAAGTGCTGGGCGTCTCGGTG
GACTCTCAGTTCACCCACCTGGCTTGGTATGAGCAGGGGCCAAAGAGGGAGGTTGCAGCTAAGCTCACAC
CCTCAGGTCCTAGCAGTGTGGCTTCGTGGCCATTGCTCAACCTCTGGAACCTGCGTTTCCCCATCGTGAA
AATAATGGAAACATTGCCGCCCAAGTCTTTAAGGATGATGACAGTAATTAGCATTTGACAACTAGTTGCC
TGGTATATAGAGTTGCAGATGCAACTCAGATGCAACTCTATCTACTCTATGTACTTAGTTCCCAGGAGGG
AGGCTGTGCTGCCCTATTTCATGAAGATGGAAACTCCAGTTCACCGAAGTGAAGGGCTGTACCCCATGAC
ACAGCTAGAGGAGGATGGGGACTCTTAACACAGGCTCTCTGCTGGGTGATGCTGCAAGTTACAAGTACAT
GTGAAGCCACTTAGCTGGAGCTGTGCCTCTCAAACTCAGTCTTCCCAGCCATGGGGATACAGTCCTTGCA
CCCAACCCAGGGTGGGGTGGGTGAGGCTCCCAGCGGCCTACTCTAAAGCCCCTTATCTCCGGCCTCCAGT
GCTTATCACATTGGGCCCACAGGGTGAGGACCCTGCTGTGCCAGGCATCCTGAGGCCCCAACTCTGTCTC
CCCTACTCCCAGGATCAACACCCCCCGGAAAGAGGGAGGCTTGGGCCCCCTGAACATCCCCCTGCTTGCT
GACGTGACCAGACGCTTGTCTGAGGATTACGGCGTGCTGAAAACAGATGAGGGCATTGCCTACAGGTACT
GTGGGACCCTCAGCCCGGCTCAGGGAGCGCCCTGCCCCCCATTCCTGTGATGCTGGGACCACTCCTGTAC
AATGTCTTCTCTGCCCCCAGCCCTGTGGCTAGCAGCGGGTGGTTGGTAGTCCCTTCCTTGTCTCTGGCAG
TGGGAGCTATCAGCTCCTCACTGGGAACCCTGATGTCTTCAGGGGCCTCTTTATCATCGATGGCAAGGGT
GTCCTTCGCCAGATCACTGTTAATGATTTGCCTGTGGGACGCTCCGTGGATGAGGCTCTGCGGCTGGTCC
AGGCCTTCCAGTACACAGACGAGCATGGGGAAGGTGAGCAGATACACACATGACACATGGGTACATACTG
AGCGCCTCCGTCACTCATGCAAACATTCACTGCCTGTCCTCTTACCTGTCCAGATGGGTGTTAGGGCCCC
AAAGAAGATTCAGCTCAGGGCTTTGTCTGCAGGATGTTTCTAATGTGGTAGGAGACAAATAACGCCTGAC
ATTCAACCAAGGTGGACAAAGGGGCCGGGCTCAGTGGCTCACGGTTGTATTGCCAGCACTTTGGGAAGCT
GTGGCAGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCTA
CGAAGAACACAAAAAATTAGCTGGCCGTGGTGGTGCACACTTGTAATCCCAGCTACTTGAGAGACTGAGG
CAGGAGTTCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCGTTGTACTCCAGCTTG
GGCAACAGAGCAAAACTCAGTCTCAAAAAAAAAAAAAAATTAGCTTGGTTTGTGAAGCATGCCTATAGTC
CCAGCTACTCAAGAGGCTGAGGCTGGAGGATCACTTGAGCCTGGGAGGTCAAGGCTGCAGTAAGCTGTGA
TCGCACCACTGCACTCCAGCCTGGGTGACACAGCAAGACCCTGTCTCAAAAAAACAAACAAACAGGCCGA
GCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCATGAGGTCAGGAGT
TTGAGACCAGCCTGGCCAACATAGTGAAACCGCGTCTCTGCTAAAAATACAAAAAAATTAGCTGGGTGCG
GTGGCAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGACTCCCTTGAACCCGGGAGGAGG
TTGCAGTAAGCCGAGATCACACCACTGCACTCCAGCCTGGGCGCCAGTGTGAGACTCCATCCCAAAAACA
ACAACAACAAAAAAACCTGTAGGGGTGGGGCAGAGGGACAAAGATGGGACTAAAGGAGCCAAAAAGACAG
GAAGATGCTGTGTCTCATGCCTGTAGATGCTGTGTCTCATGCCTGTAGTTCCACCTACTCTGGAGAGTGA
GGCAGAAGACTGCTTAGGCCCAGGAATTTGAGTCGAGCCTAGGCAACATAGCAATACCCCATCTCTTTTT
TTTTTTTTTTTAAGAGATGGGGTATTGGTT


>OriGene 5' read for AK022395 unedited
ATACGACTCACTATAGGCGGCCGCGAATCGGCACGGAGGCCAACCCAGGTGGGGTGGGTG
AGGCTCCCAGCGGCCTACTCTAAAGCCCCTTATCTCCGGCCTCCAGTGCTTATCACATTG
GGCCCACAGGGTGAGGACCCTGCTGTGCCAGGCATCCTGAGGCCCCAACTCTGTCTCCCC
TACTCCCAGGATCAACACCCCCCGGAAAGAGGGAGGCTTGGGCCCCCTGAACATCCCCCT
GCTTGCTGACGTGACCAGACGCTTGTCTGAGGATTACGGCGTGCTGAAAACAGATGAGGG
CATTGCCTACAGGTACTGTGGGACCCTCAGCCCGGCTCAGGGAGCGCCCTGCCCCCCATT
CCTGTGATGCTGGGACCACTCCTGTACAATGTCTTCTCTGCCCCCAGCCCTGTGGCTAGC
AGCGGGTGGTTGGTAGTCCCTTCCTTGTCTCTGGCAGTGGGAGCTATCAGCTCCTCACTG
GGAACCCTGATGTCTTCAGGGGCCTCTTTATCATCGATGGCAAGGGTGTCCTTCGCCAGA
TCACTGTTAATGATTTGCCTGTGGGACGCTCCGTGGATGAGGCTCTGCGGCTGGTCCAGG
CCTTCCAGTACACAGACGAGCATGGGGAAGGTGAGCAGATACACACATGACACATGGGTA
CATACTGAGCGCCTNCGTCACTCATGCAAACATTCACTGCCTGTCCTCTTACCTGTCCAG
ATGGGTGNNTANGGCCCCAAAGAAGATTCAGCTCANGGCTTTGTCTGCAGGATGTTTCTA
ATGTGGTANGAGACAAATAACGCCTGACATTCAAACCAAGTGGACAAAGGGCCGNGCTCA
GTGCTCACGGTTGTATTGCCAGCACTTTGGGAAGCTGTGGCACGTGGATCACCTGAGTTC
ANGAGGTCCGAAACCAGCCTGACAACATGGTTGAAAACCCGTCTCTACAAGACACANAAA
ATAGCTGGA
Restriction Sites NotI-NotI     
ACCN AK022395
Insert Size 2500 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq AK022395.1
RefSeq Size 3180 bp
RefSeq ORF 3180 bp
Locus ID 7001
Cytogenetics 19p13.13
Protein Families Druggable Genome
Gene Summary 'This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]'

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