Peroxiredoxin 2 (PRDX2) (AK022395) Human Untagged Clone

CAT#: SC101510

(untagged)-Human cDNA FLJ12333 fis, clone MAMMA1002198, highly similar to THIOREDOXIN PEROXIDASE 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PRDX2
• Synonyms: HEL-S-2a|NKEF-B|NKEFB|PRP|PRX2|PRXII|PTX1|TDPX1|TPX1|TSA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AK022395, the custom clone sequence may differ by one or more nucleotides
  
  
  ACGTCTTGGTTCGGGCCGGGCATAAAAGGCTTCGCGGCCCAGGGCTCACTTGGCGCTGAGAACGCGGGTC
  CACGCGTGTGATCGTCCGTGCGTCTAGCCTTTGCCCACGCAGGTATGAACACCCGGAGTGCACCTGGCGG
  GAGGACCCCCTTCAGGCTGCTTTGGCCCGATCCTGACTTTAGTGCTGGCCGCCTTTGCTTTCCATCCGCT
  ATAGTGGCCTCCTTTGTCCTTGCGGGGGAAACCGAGGCCACAGCCTTGCAGCGCAGTCCTGATCGCCCGA
  CTTCCCGCCCCCTGCTCGTGCGGGCCTCACTGTCTCCTTCTGGGCTGGGGGCTTGCGACACCGCCCTCCG
  GCCGACTCGCTCGTGGGGTGCTGGTGGCAGTGGCTGGGTCACTCGTGCTCTGGTCAGGAGAGCGGGTCTC
  CGGCAGCCTCCGGGCCTCGTAGACCGGGTACCCGGGAGGGTGAGGGTTAGTGCTGTCGCCTCCGCCGTGC
  TGACTCAGTCATAGGGCCCAGCACGCAGCGCGACCTTGGGTTGGGAGGACAAAGTGTCTTCCCGGGCGCA
  CTGACCGGGCGGGGGTCTCAGCTTTCAGTCATGGCCTCCGGTAACGCGCGCATCGGAAAGCCAGCCCCTG
  ACTTCAAGGCCACAGCGGTGGTTGATGGCGCCTTCAAAGAGGTGAAGCTGTCGGACTACAAAGGTGAGCG
  CCGCCCGGAGGGGGCCCAGGTAGAAGCGGGGCCGTGCATGAGAGAAGCTGGGCCCTAACTCCTCTGTGTC
  CCTCCTCCCCAGGGAAGTACGTGGTCCTCTTTTTCTACCCTCTGGACTTCACTTTTGTGTGCCCCACCGA
  GATCATCGCGTTCAGCAACCGTGCAGAGGACTTCCGCAAGCTGGGCTGTGAAGTGCTGGGCGTCTCGGTG
  GACTCTCAGTTCACCCACCTGGCTTGGTATGAGCAGGGGCCAAAGAGGGAGGTTGCAGCTAAGCTCACAC
  CCTCAGGTCCTAGCAGTGTGGCTTCGTGGCCATTGCTCAACCTCTGGAACCTGCGTTTCCCCATCGTGAA
  AATAATGGAAACATTGCCGCCCAAGTCTTTAAGGATGATGACAGTAATTAGCATTTGACAACTAGTTGCC
  TGGTATATAGAGTTGCAGATGCAACTCAGATGCAACTCTATCTACTCTATGTACTTAGTTCCCAGGAGGG
  AGGCTGTGCTGCCCTATTTCATGAAGATGGAAACTCCAGTTCACCGAAGTGAAGGGCTGTACCCCATGAC
  ACAGCTAGAGGAGGATGGGGACTCTTAACACAGGCTCTCTGCTGGGTGATGCTGCAAGTTACAAGTACAT
  GTGAAGCCACTTAGCTGGAGCTGTGCCTCTCAAACTCAGTCTTCCCAGCCATGGGGATACAGTCCTTGCA
  CCCAACCCAGGGTGGGGTGGGTGAGGCTCCCAGCGGCCTACTCTAAAGCCCCTTATCTCCGGCCTCCAGT
  GCTTATCACATTGGGCCCACAGGGTGAGGACCCTGCTGTGCCAGGCATCCTGAGGCCCCAACTCTGTCTC
  CCCTACTCCCAGGATCAACACCCCCCGGAAAGAGGGAGGCTTGGGCCCCCTGAACATCCCCCTGCTTGCT
  GACGTGACCAGACGCTTGTCTGAGGATTACGGCGTGCTGAAAACAGATGAGGGCATTGCCTACAGGTACT
  GTGGGACCCTCAGCCCGGCTCAGGGAGCGCCCTGCCCCCCATTCCTGTGATGCTGGGACCACTCCTGTAC
  AATGTCTTCTCTGCCCCCAGCCCTGTGGCTAGCAGCGGGTGGTTGGTAGTCCCTTCCTTGTCTCTGGCAG
  TGGGAGCTATCAGCTCCTCACTGGGAACCCTGATGTCTTCAGGGGCCTCTTTATCATCGATGGCAAGGGT
  GTCCTTCGCCAGATCACTGTTAATGATTTGCCTGTGGGACGCTCCGTGGATGAGGCTCTGCGGCTGGTCC
  AGGCCTTCCAGTACACAGACGAGCATGGGGAAGGTGAGCAGATACACACATGACACATGGGTACATACTG
  AGCGCCTCCGTCACTCATGCAAACATTCACTGCCTGTCCTCTTACCTGTCCAGATGGGTGTTAGGGCCCC
  AAAGAAGATTCAGCTCAGGGCTTTGTCTGCAGGATGTTTCTAATGTGGTAGGAGACAAATAACGCCTGAC
  ATTCAACCAAGGTGGACAAAGGGGCCGGGCTCAGTGGCTCACGGTTGTATTGCCAGCACTTTGGGAAGCT
  GTGGCAGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCTA
  CGAAGAACACAAAAAATTAGCTGGCCGTGGTGGTGCACACTTGTAATCCCAGCTACTTGAGAGACTGAGG
  CAGGAGTTCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCGTTGTACTCCAGCTTG
  GGCAACAGAGCAAAACTCAGTCTCAAAAAAAAAAAAAAATTAGCTTGGTTTGTGAAGCATGCCTATAGTC
  CCAGCTACTCAAGAGGCTGAGGCTGGAGGATCACTTGAGCCTGGGAGGTCAAGGCTGCAGTAAGCTGTGA
  TCGCACCACTGCACTCCAGCCTGGGTGACACAGCAAGACCCTGTCTCAAAAAAACAAACAAACAGGCCGA
  GCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCATGAGGTCAGGAGT
  TTGAGACCAGCCTGGCCAACATAGTGAAACCGCGTCTCTGCTAAAAATACAAAAAAATTAGCTGGGTGCG
  GTGGCAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGACTCCCTTGAACCCGGGAGGAGG
  TTGCAGTAAGCCGAGATCACACCACTGCACTCCAGCCTGGGCGCCAGTGTGAGACTCCATCCCAAAAACA
  ACAACAACAAAAAAACCTGTAGGGGTGGGGCAGAGGGACAAAGATGGGACTAAAGGAGCCAAAAAGACAG
  GAAGATGCTGTGTCTCATGCCTGTAGATGCTGTGTCTCATGCCTGTAGTTCCACCTACTCTGGAGAGTGA
  GGCAGAAGACTGCTTAGGCCCAGGAATTTGAGTCGAGCCTAGGCAACATAGCAATACCCCATCTCTTTTT
  TTTTTTTTTTTAAGAGATGGGGTATTGGTT
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AK022395 unedited
  ATACGACTCACTATAGGCGGCCGCGAATCGGCACGGAGGCCAACCCAGGTGGGGTGGGTG
  AGGCTCCCAGCGGCCTACTCTAAAGCCCCTTATCTCCGGCCTCCAGTGCTTATCACATTG
  GGCCCACAGGGTGAGGACCCTGCTGTGCCAGGCATCCTGAGGCCCCAACTCTGTCTCCCC
  TACTCCCAGGATCAACACCCCCCGGAAAGAGGGAGGCTTGGGCCCCCTGAACATCCCCCT
  GCTTGCTGACGTGACCAGACGCTTGTCTGAGGATTACGGCGTGCTGAAAACAGATGAGGG
  CATTGCCTACAGGTACTGTGGGACCCTCAGCCCGGCTCAGGGAGCGCCCTGCCCCCCATT
  CCTGTGATGCTGGGACCACTCCTGTACAATGTCTTCTCTGCCCCCAGCCCTGTGGCTAGC
  AGCGGGTGGTTGGTAGTCCCTTCCTTGTCTCTGGCAGTGGGAGCTATCAGCTCCTCACTG
  GGAACCCTGATGTCTTCAGGGGCCTCTTTATCATCGATGGCAAGGGTGTCCTTCGCCAGA
  TCACTGTTAATGATTTGCCTGTGGGACGCTCCGTGGATGAGGCTCTGCGGCTGGTCCAGG
  CCTTCCAGTACACAGACGAGCATGGGGAAGGTGAGCAGATACACACATGACACATGGGTA
  CATACTGAGCGCCTNCGTCACTCATGCAAACATTCACTGCCTGTCCTCTTACCTGTCCAG
  ATGGGTGNNTANGGCCCCAAAGAAGATTCAGCTCANGGCTTTGTCTGCAGGATGTTTCTA
  ATGTGGTANGAGACAAATAACGCCTGACATTCAAACCAAGTGGACAAAGGGCCGNGCTCA
  GTGCTCACGGTTGTATTGCCAGCACTTTGGGAAGCTGTGGCACGTGGATCACCTGAGTTC
  ANGAGGTCCGAAACCAGCCTGACAACATGGTTGAAAACCCGTCTCTACAAGACACANAAA
  ATAGCTGGA
  
• Restriction Sites: NotI-NotI
• ACCN: AK022395
• Insert Size: 2500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: AK022395.1
• RefSeq Size: 3180 bp
• RefSeq ORF: 3180 bp
• Locus ID: 7001
• Cytogenetics: 19p13.13
• Protein Families: Druggable Genome
• Gene Summary: 'This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]'