Thimet Oligopeptidase (THOP1) (AK093392) Human Untagged Clone

CAT#: SC101511

(untagged)-Human cDNA FLJ36073 fis, clone TESTI2019697, highly similar to THIMET OLIGOPEPTIDASE (EC 3.4.24.15)

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Reconstitution Protocol

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Size
    • 10 ug
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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol THOP1
Synonyms EP24.15|MEPD_HUMAN|MP78|TOP
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for AK093392, the custom clone sequence may differ by one or more nucleotides


ATGTTCAGCGGGACCCACGTGGAGCGGGACTTTGTGGAGGCGCCGTCGCAGATGCTGGAGAACTGGGTGT
GGGAGCAGGAGCCGCTGCTGCGGATGTCGCGGCACTACCGCACAGGCAGCGCCGTGCCCCGGGAGCTCCT
GGAGAAGCTCATTGAGTCCCGGCAGGCCAACACAGGCCTCTTCAACCTGCGCCAGATCGTCCTCGCCAAG
GTGGACCAGGCCCTGCACACGCAGACGGACGCAGACCCCGCCGAGGAGTATGCGCGGCTCTGCCAGGAGA
TCCTCGGGGTCCCGGCCACGCCAGGAACCAACATGCCTGCAACCTTCGGCCATCTGGCAGGTGGCTACGA
CGCCCAGTACTACGGGTACCTGTGGAGCGAGGTGTATTCCATGGACATGTTCCACACGCGCTTCAAGCAG
GAGGGTGTCCTGAACAGCAAGTTTCCTCACTATGAAGTGCGGCCGTTACGCCATGTGAGCCTGTGCCTCC
CGCTGACTTGGTGTGACCCAGGCTCGGGACAGCCGCCAGAGTCCCTCACAAGGAACAGGTGGCTACCAGC
TTTGAGGGCCGGCCCTGCCCTGCCTGGGTGCAACATTGCACTGGGCAGCCTGCAGGTTGGCATGGATTAC
AGAAGCTGCATCCTGAGACCCGGCGGTTCCGAGGATGCCAGCGCCATGCTGAGGCGCTTCCTGGGCCGTG
ACCCCAAGCAGGACGCCTTCCTCCTGAGCAAGGGGCTGCAGGTCGGGGGCTGCGAGCCCGAGCCGCAGGT
CTGCTGA

>OriGene 5' read for AK093392 unedited
TTGTAATACGATCTCACTATAGGGCGGCCGCGAATCGGCACGAGGCCTCGTGCCGAATTC
GGCACGAGGGAGCGCCGGGGCCTGCCCTTCGACGGCCGCATCCGTGCCTGGGACATGCGC
TACTACATGAACCAGGTGGAGGAGACGCGCTACTGCGTGGACCAGAACCTGCTCAAGGAG
TACTTCCCCGTGCAGGTGGTCACGCACGGGCTGCTGGGCATCTACCAGGAGCTCCTGGGG
CTGGCCTTCCACCACGAGGAGGGCGCCAGTGCCTGGCATGAGGACGTGCGGCTCTACACC
GCGAGGGACGCGGCCTCGGGGGAGGTGGTCGGCAAGTTCTACCTGGACCTGTACCCGCGG
GAAGGAAAGTACGGGCACGCGGCCTGCTTTGGCCTGCAGCCCGGCTGCCTGCGGCAGGAT
GGGAGCCGCCAGATCGCCATCGCGGCCATGGTGGCCAACTTCACCAAGCCCACAGCCGAC
GCGCCCTCGCTGCTGCAGCATGACGAGGTGGAGACCTACTTCCATGAGTTTGGCCACGTG
ATGCACCAGCTCTGCTCCCAGGCGGAGTTCGCCATGTTCAGCGGGACCCACGTGGAGCGG
GACTTTGTGGAGGCGCCGTCGCAGATGCTGGAGAACTGGGTGTGGGAGCAGGAGCCGCTG
CTGCGGATGTCGCGGCACTACCGCACAGGCAGCGCCGTGCCCCGGGAGCTCCTGGAGAAG
CTCATTGAGTCCCGGCAGGCCAACACAGGCCTCTTNCACCTGCGCCAGATCGTNCTCGCC
AAGGTGACCANGCCCTGCACACGCAGACGGACGCANACCCCGNCGAGGAGTATGCGCGGC
TCTGCCAGGAGATCCTCGGGGTCCCGGCCCGCCAGGACAACATGCCTGCACCTTCGCCAT
TTGGAGTGGCTAGACGCCCATN
>OriGene 3' read for AK093392 unedited
AAAAATTGGGGGTTNAGAAAGCGTAATCNAGGATTTANCCGTACAAATGNACAAGGGNNN
ACGTTTCCCAGAATATTATACGTGTTAGTGCAACAAAGACCAGCCCTGGCAGCCACGAAA
GCCCTCCAGATGCCTTGAGGACGCCGTCTCTAGCCGGGTGGGCCACGACCGGGTGGGGAC
AGACAATGACAAGAGGCAAGACAGCCGCTCAGCCACCCTGCCTTACCTAGCTCTGTGCCA
GAGCCTGCCCCATCCTGTGCCGGGGGCTAATGCACCAGGGCGGCGGGAGCGCAGGCCAGA
CTGGGCAGTCGCAGTGCCAGGCCTCAGCAGACCTGCGGCTCGGGCTCGCAGCCCCCGACC
TGCAGCCCCTTGCTCAGGAGGAAGGCGTCCTGCTTGGGGTCACGGCCCAAGAAGCGCCTC
AGCATGGCGCTGGCATCCTCGGAACCGCCGGGTCTCAGGATGCAGCTTCTGTAATCCATG
CCAACCTTGCTGTTCAGGACACCCTCCTGCTTGAAGCGCGTGTGGAACATGTCCATGGAA
TACACCTCGCTCCACAGGTACCCGTAGTACTGGGCGTCGTAGCCACCTGCCAAATGGCCG
NAAGTTGCAGGCATGTTGGTTCCTGGCGTGGCCGGGACCCCGAGGATCTCCTGGCAAAGC
CGCGCATACTCCTCGGCGGAGTCTGCGTCCGTCTGCGTGTGCAGGGCCTGGTCCACCTTG
GCGAGGACGATCTTGGCGCATGTTTGAAAGAGGCCCTGTGATAGGCCTTGCCTGGGACTC
AATGAGCTTCTTCAGGAGCTTCCGGGGCACGCGCTGCCTGTGCGGTAGTGCCGCGAAATT
CAGCAAAAACGGGCTCCTGGTTCCACAACCAGTTTTCCAGCATCTGGGAGGCGCCCTCCA
CAAATTCCAGCTCCACGTGGGTTCCCGCTGAACATGGA
Restriction Sites NotI-NotI     
ACCN AK093392
ORF Size 1887 bp
Insert Size 1500
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq AK093392.1, BAG52704.1
RefSeq Size 1887
RefSeq ORF 1887
Locus ID 7064
Protein Families Druggable Genome, Protease
Protein Pathways Renin-angiotensin system
Gene Summary The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015]

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