XIAP (AK098439) Human Untagged Clone

CAT#: SC101707

(untagged)-Human cDNA FLJ25573 fis, clone JTH06531


Reconstitution Protocol

USD 660.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol XIAP
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for AK098439, the custom clone sequence may differ by one or more nucleotides


ATTTCCATGAGAACAAAGGCTTATTCCTTTAACTTAAACCCCAAACTTTGTTATTTTAATTATTTTCAGG
CAATCATCTTTATATACTTTCCTTACAAACCCAGTGGTTGAGAGCATAGGCCTTGGTGGCAGGTGCATCT
GGGCTTGGGGGCTTCTGCCACACTTACTACTCTGTGACTTGGGAAGCTCTTAAGGCTCCCAAGGCTCCGT
TTCTTATGTGGAAGAAGAATAGCAGGAGGACTCACCTCTGCGGGTTGTTGTGAGGATTAACTGGGTGATG
ACTGTAAGCAGCTGGGAGAGTGCCTTGTGTGCAGTGACCACTGTTGCTGCCACCATGATTATGTCACCTC
TCAACATGGGGTGGTGGGAGGCCCTGTGGATGAGGCCAAGGCTGCCTGCACTGAGTGTCCCAGGCCTTAT
AGCTTTCCACATTCTCACGTCTGCTGCCACATGATATACAAGTAAATGTATTAGAAGTTGGTGTTCATAA
AATACTTCTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCCGTCACCCAGGCTGGAGTGCAGTGGCGCC
ATCTCCCAGGCTCAAGGGATCCTCCTGCCTCGGCCTGCCAAGTAGCTGGGACTACAAGTGCACACCAGTA
TGCCCAACTAATTTTTTGTATTTTTAGAACAGGTGTGGTTTCACCATATTGCCCAGGCTGGTCTCGAGCT
CCTGAGCTCAGGCAATCCGCCTGCCTCAACCTCCCAAAGTGCTGGGATTACAGGTGTGAGCATCCAGCCA
GAAAATGATTTGCTTTCTAGACCCATATCACCTCTCTCCATCTACATCTCTAGTATTTAAATTCAACACA
ATTCTAGATAGCTGAAACAGCCCAAAATATGTGTTTAGAATACTTAGAGTTTGTTATAAATAACCCTCTG
TTTAGAATTTGCCCAGTGAAATTCTCTAATAATACTTAAAACTCTTTACTAAAGTTGAATTTTCCTTTTT
TTTCATTGAAATAGCAAAGGTAGTAATCTGTATTGGTCAAAGAAACGAGATAATTCCTAGATCTCTGTTT
TAGACCAGTAGACCTAACTGTGCTTTCTTAACTTGGATGTTACATGAAACTTAAAAACAAACAAATATGT
GTTACAAGTACTTGTGTGTACGTGCATGTGTGTTTGTGCATGTGTCTGTGTGTGTGGAACTTTTGTACCT
TTGCATAAAGAAGGTTATTTAACAAAGTGGTACAAACAGTGAACTACTTAATCCTTCTATGGTATCATAC
ACTTCTTTTCCTGGTTAGGTTATGAGACTGGCAGAGGTAGGAGTATATAATGTGCTCAGCTTGTCTTGAT
TTCAATAAGACATTTGATAAAGTCATTCTTGATCTCTGAATGTGAAAAGGAAGTAGAACAGCCGGGCGCG
GTGGCTCACGCCTGTAATCCCAGGACTTTGGGAGGCCAAGGCGGGCAGATCACCTGAGGTCGGCAGTTTG
AGACCAGCCTGACCAACGTGGAGAAACCCCGTCTCTATTAAAAATACAAAATTAGCCGGGCATGGTGGCA
CATGTGTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCTCTTGAACCCAGGAGGCGGAGGTTG
CGGTGAGCCGAGATGGTGCCGTTGCACTCCAGCCGGGCAACAAGGGCTAAACTCCATCTCAAAAGAAAAG
AAAGAAAGGGAAGTAGAAGTAGGATTTAACAAAGGACCGAGAAGTCGGCTGAATAGCCAGGTTCAGACAG
TGTTGGCAAGAACGGATCTTTGGCAAGATCACTTAAGGTGAGCTACTCTAGCAGCATCCTGTTTGACATT
TGTATCCATAACTTGAATAAAAATATAGAAGGCAAAGAAGAGTGCTGGGCAAGATGTGTTGGGTGTTAGA
TCTGCAATACTCTTCATAGTGTAATGGCTAAATGTAAAGTCTTACGTCTCGGTTCAAGAAAGCACGTTGC
TATATGAAATTTCAGAAAAAAGTTTTGTTGCGGGGGGTGGGATATTGATCATTTGAACATATGCCAGTTG
TTTCTCCTGCCCTAGGGGAGGTTGGCACGGCAACCTTCCCACTCCGTAGGTGGGTAGCCTTGCTGATGGG
GCACGTCGTCACCAAGGGACCTGATTGTTGTCATGGTTTTGTCTTGTCCTCCTCCCTGGTGAAAGTCTAC
TGCAGTTTTATTCTCAGCTCTGGAAGGAGAGGGAACGAGCCTCTGCCTGTGTGTCCTGACCCCTCTTGCC
TTGTTTTTGATCTGCTCAGGCCGGGTGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCAAAGG
CAGGTGGATCACTTGAGGTCAGGAGTTCAAGACTAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAA
AAATACAAAAATTAGCCAAGTGTGTTGGTGGGCCCCTGTAATCCCAGCTACTCGGGAGGTTGAGGGAGGA
GAATCACTTGACCCCAGGAGGCGGAGGTTGAAGTGAGCCAGGATTGTGCCACTGTACTCCAGCCTGGGCG
ACAGAGGGGGACTCTGTCTCAC


>OriGene 5' read for AK098439 unedited
GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCCGAATTCGG
CACGAGGGTTGGGTGTTAGATCTGCAATACTCTTCATAGTGTAATGGCTAAATGTAAAGT
CTTACGTCTCGGTTCAAGAAAGCACGTTGCTATATGAAATTTCAGAAAAAAGTTTTGTTG
CGGGGGGTGGGATATTGATCATTTGAACATATGCCAGTTGTTTCTCCTGCCCTAGGGGAG
GTTGGCACGGCAACCTTCCCACTCCGTAGGTGGGTAGCCTTGCTGATGGGGCACGTCGTC
ACCAAGGGACCTGATTGTTGTCATGGTTTTGTCTTGTCCTCCTCCCTGGTGAAAGTCTAC
TGCAGTTTTATTCTCAGCTCTGGAAGGAGAGGGAACGAGCCTCTGCCTGTGTGTCCTGAC
CCCTCTTGCCTTGTTTTTGATCTGCTCAGGCCGGGTGCAGTGGCTCACGCCTGTAATCCC
AGCACTTTGGGAGGCAAAGGCAGGTGGATCACTTGAGGTCAGGAGTTCAAGACTAGCCTG
GCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAAGTGTGTTGGTG
GGCCCCTGTAATCCCAGCTACTCGGGAGGTTGAGGGAGGAGAATCACTTGACCCCAGGAG
GCGGAGGTTGAAGTGAGCCAGGATTGTGCCACTGTACTCCAGCCTGGGCGACAGAGGGGG
GACTCTGTCTCACANNAAATAAAAAATTAAAAAAAAGGTCTGCTCAGAATAGGGGAAACA
CGGGATCAAGATCATTANAGATTTATAGGCTGGGATGCACACCATGTCTTCAGAGCTAGC
CCGGCTGTGTCTTCTGCCCGTTTCTTTACTGGTGAATACCCTTTCGNNTGACCANCANNT
GATGTTCTCTCCTA
Restriction Sites NotI-NotI     
ACCN AK098439
Insert Size 4000 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq AK098439.1
RefSeq Size 2542 bp
RefSeq ORF 2542 bp
Locus ID 331
Cytogenetics Xq25
Protein Families Druggable Genome
Protein Pathways Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis
Gene Summary 'This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]'

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