SCIN (NM_033128) Human Untagged Clone

CAT#: SC101747

SCIN (untagged)-Human scinderin (SCIN), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SCIN
• Synonyms: KIAA1905
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC101747 sequence for NM_033128 edited (data generated by NextGen Sequencing)
  ATGGCTAAACTATACATGGTTTCAGATGCAAGTGGCTCCATGAGAGTGACTGTGGTGGCA
  GAAGAAAACCCCTTCTCAATGGCAATGCTGCTGTCTGAAGAATGCTTTATTTTGGACCAC
  GGGGCTGCCAAACAAATTTTCGTATGGAAAGGTAAAGATGCTAATCCCCAAGAGAGGAAG
  GCTGCAATGAAGACAGCTGAAGAATTTCTACAGCAAATGAATTATTCCAAGAATACCCAA
  ATTCAAGTTCTTCCAGAAGGAGGTGAAACACCAATCTTCAAACAGTTTTTTAAGGACTGG
  AGAGATAAAGATCAGAGTGATGGCTTCGGGAAAGTTTATGTCACAGAGAAAGTGGCTCAA
  ATAAAACAAATTCCCTTTGATGCCTCAAAATTACACAGTTCTCCGCAGATGGCAGCCCAG
  CACAATATGGTGGATGATGGTTCTGGCAAAGTGGAGATTTGGCGTGTAGAAAACAATGGT
  AGGATCCAAGTTGACCAAAACTCATATGGTGAATTCTATGGTGGTGACTGCTACATCATA
  CTCTACACCTATCCCAGAGGACAGATTATCTACACGTGGCAAGGAGCAAATGCCACACGA
  GATGAGCTGACAACATCTGCGTTCCTGACTGTTCAGTTGGATCGGTCCCTTGGAGGACAG
  GCTGTGCAGATCCGAGTCTCCCAAGGCAAAGAGCCTGTTCACCTACTGAGTTTGTTCAAA
  GACAAACCGCTCATTATTTACAAGAATGGAACATCAAAGAAAGGAGGTCAGGCACCTGCT
  CCCCCTACACGCCTCTTTCAAGTCCGGAGAAACCTGGCATCTATCACCAGAATTGTGGAG
  GTTGATGTTGATGCAAATTCACTGAATTCTAACGATGTTTTTGTCCTGAAACTGCCACAA
  AATAGTGGCTACATCTGGGTAGGAAAAGGTGCTAGCCAGGAGGAGGAGAAAGGAGCAGAG
  TATGTAGCAAGTGTCCTAAAGTGCAAAACCTTAAGGATCCAAGAAGGCGAGGAGCCAGAG
  GAGTTCTGGAATTCCCTTGGAGGGAAAAAAGACTACCAGACCTCACCACTACTGGAAACC
  CAGGCTGAAGACCATCCACCTCGGCTTTACGGCTGCTCTAACAAAACTGGAAGATTTGTT
  ATTGAAGAGATTCCAGGAGAGTTCACCCAGGATGATTTAGCTGAAGATGATGTCATGTTA
  CTAGATGCTTGGGAACAGATATTTATTTGGATTGGCAAAGATGCTAATGAAGTTGAGAAA
  AAAGAATCTCTGAAGTCTGCCAAAATGTACCTTGAGACAGACCCTTCTGGAAGAGACAAG
  AGGACACCAATTGTCATCATAAAACAGGGCCATGAGCCACCCACATTCACAGGCTGGTTC
  CTGGGCTGGGATTCCAGCAAGTGGTAA
  
  Clone variation with respect to NM_033128.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_033128 unedited
  GGTTGTGCGAATTTTGTAATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCAAG
  CCAGTGCAGAATAGAGAACTTCAAGNATATGAGTCTAATGACTTTGTTAGCTATTTCAAA
  GGCGGTCTGAAATACAAGGCTGGAGGCGTGGCATCTGGATTAAATCATGTTCTTACGAAC
  GACCTGACAGCCAAGAGGCTCCTACATGTGAAGGGTCGTAGAGTGGTGAGAGCCACAGAA
  GTTCCCCTTAGCTGGGACAGTTTCAACAAGGGTGACTGCTTCATCATTGACCTTGGCACC
  GAAATTTATCAGTGGTGTGGTTCCTCGTGCAACAAATATGAACGTCTGAAGGCAAACCAG
  GTAGCTACTGGCATTCGGTACAATGAAAGGAAAGGAAGGTCTGAACTAATTGTCGTGGAA
  GAAGGAAGTGAACCCTCAGAACTTATAAAGGTCTTAGGGGAAAAGCCAGAGCTTCCAGAT
  GGAGGTGATGATGATGACATTATAGCAGACATAAGTAACAGGAAAATGGCTAAACTATAC
  ATGGTTTCAGATGCAAGTGGCTCCATGAGAGTGACTGTGGTGGCAGAAGAAAACCCCTTC
  TCAATGGCAATGCTGCTGTCTGAAGAATGCTTTATTTTGGACCACGGNGCTGCCAAACAA
  ATTTTCGTATGGAAAGGTAAAGATGCTAATCCCCAAGAGAGGAAGGCTGCAATGAAGACA
  GCTGAAGAATTTCTACAGCAAATGAATTATTCCAAGAATACCCAAATTCAAGTTCTTCCA
  GAAAGAGGTGAAACACCAATCTTCAAACAGTTNTTTAAGGACTGGAGAGATAAGATCAGA
  GTGATGGCTTCGGNAAAAGTTATGTCACAGAGAAAGTGGCTCANATAAACAAATTCCTTT
  GATGCCTCAAATTAACAGTTCTNCGCAGATGCAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_033128 unedited
  GTTTTAGCTNTGNACCGCGCGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTTTTT
  TTTTGGGGTTTCAAAGGCTTTTAATAAGGGTAAAAAAAAAAAAAATTCCTCTTAAAAAAA
  ACACTTAGCAGTTAATGACATCAAAGTCATATTGACTAAAGAAGGAAAATAGCAACCAAT
  TGTTAAAGCCACCTTAACATAAACCTTATTGCAAGTATACACATCTTTTGAACACAATCT
  ATAGAAAAGAGAATAACTTCCAAGGCATTACAACTTTTTCTCTGGCATGTTAAAAAACAA
  CTCTGACTAATGGCTAATGCATTATAAAATTTCCTATCTGACAAATCTTTCTAGATTATG
  CATAGTATTTTACTTTTGAAAGGGCATAAAAAAGATATAAATCAGTTTCCATAAGAGCTA
  ATATTGGCCCATAACGAAAGTTTCCTTCAGGGTATTTTAATGTATTAACGTAAGAAAACT
  CCAGGTGAAGAAGAATTTCAAGCCAAAACTAAGCATTAAAAAATAGGCGTTTGGTTGAGG
  GTAATTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCTGTTGCCCAAGCTGGAGTGTGG
  TGGCGCAATCCTGGCTCACTGCAACCTCAGCCTCCTGGGTTCAAGCAATTTTCCTGGCTC
  AACCTTCCAAGTAACAGGGACTACAGGCGTGCACCACCACGCGCAGCTAATTTTTTTGTA
  TTTTTAANAGAAGCGAAGGTTCGCCATGTTGGCCAAGCCTGTCTTCGAAATCCTGACCCC
  AGTGATCCCGCCTACTCATCCTCTCAAATGCCTGGATTACAGGTGGTGAGCCCCCGGCCC
  CACCCTAATTTTTAAAAAACAAAAAGCCAAAAAGCTTTTCCCGTTCCTCTTCCAAAACAG
  AAAGAGAAACCTGCCCTGGAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_033128
• ORF Size: 1407 bp
• Insert Size: 2870
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_033128.1, NP_149119.1
• RefSeq Size: 2571
• RefSeq ORF: 1407
• Locus ID: 85477
• Domains: GEL, Gelsolin
• Protein Pathways: Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton
• Gene Summary: SCIN is a Ca(2+)-dependent actin-severing and -capping protein (Zunino et al., 2001 [PubMed 11568009]). [supplied by OMIM, May 2010]
  Transcript Variant: This variant (2) lacks three exons and includes an alternate exon in the 5' end resulting in use of a downstream start codon, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.