DEDD (NM_032998) Human Untagged Clone

CAT#: SC101980

DEDD (untagged)-Human death effector domain containing (DEDD), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DEDD
• Synonyms: CASP8IP1; DEDD1; DEFT; FLDED1; KE05
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_032998, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGGCCTAAAGCGGCGGGCAAGCCAGGTGTGGCCAGAAGAGCATGGTGAGCAGGAACATGGGCTGT
  ACAGCCTGCACCGCATGTTTGACATCGTGGGCACTCATCTGACACACAGAGATGTGCGCGTGCTTTCTTT
  CCTCTTTGTTGATGTCATTGATGACCACGAGCGTGGACTCATCCGAAATGGACGTGACTTCTTATTGGCA
  CTGGAGCGCCAGGGCCGCTGTGATGAAAGTAACTTTCGCCAGGTGCTGCAGCTGCTGCGCATCATCACTC
  GCCACGACCTGCTGCCCTACGTCACCCTCAAGAGGAGACGGGCTGTGTGCCCTGATCTTGTAGACAAGTA
  TCTGGAGGAGACATCAATTCGCTATGTGACCCCCAGAGCCCTCAGTGATCCAGAACCAAGGCCTCCCCAG
  CCCTCTAAAACAGTGCCTCCCCACTATCCTGTGGTGTGTTGCCCCACTTCGGGTCCTCAGATGTGTAGCA
  AGCGGCCAGCCCGAGGGAGAGCCACACTTGGGAGCCAGCGAAAACGCCGGAAGTCAGTGACACCAGATCC
  CAAGGAGAAGCAGACATGTGACATCAGACTGCGGGTTCGGGCTGAATACTGCCAGCATGAGACTGCTCTG
  CAGGGCAATGTCTTCTCTAACAAGCAGGACCCACTTGAGCGCCAGTTTGAGCGCTTTAACCAGGCCAACA
  CCATCCTCAAGTCCCGGGACCTGGGCTCCATCATCTGTGACATCAAGTTCTCTGAGCTCACCTACCTCGA
  TGCATTCTGGCGTGACTACATCAATGGCTCTTTATTAGAGGCACTTAAAGGTGTCTTCATCACAGACTCC
  CTCAAGCAAGCTGTGGGCCATGAAGCCATCAAGCTGCTGGTAAATGTAGACGAGGAGGACTATGAGCTGG
  GCCGACAGAAACTCCTGAGGAACTTGATGCTGCAAGCATTGCCCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032998 unedited
  ATTATGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGATGGATCCAACA
  TGGCGGCGCCGAGCCTGAGCCGAGAGAAGAGACCTGGGAAATTAAGTTTCTTGCGGAGTA
  CGGTGGCGATTGCAGCTGCTGAGCAGGGATTCTGGAAAGCATTGCGTACCTGAGCCCCCA
  GCATGGCGGGCCTAAAGCGGCGGGCAAGCCAGGTGTGGCCAGAAGAGCATGGTGAGCAGG
  AACACGGGCTGTACAGCCTGCACCGCATGTTTGACATCGTGGGCACTCATCTGACACACA
  GAGATGTGCGCGTGCTTTCTTTCCTCTTTGTTGATGTCATTGATGACCACGAGCGTGGAC
  TCATCCGAAATGGACGTGACTTCTTATTGGCACTGGAGCGCCAGGGCCGCTGTGATGAAA
  GTAACTTTCGCCAGGTGCTGCAGCTGCTGCGCATCATCACTCGCCACGACCTGCTGCCCT
  ACGTCACCCTCAAGAGGAGACGGGCTGTGTGCCCTGATCTTGTAGACAAGTATCTGGAGG
  AGACATCAATTCGCTATGTGACCCCCAGAGCCCTCAGTGATCCAGAACCAAGGCCTCCCC
  AGCCCTCTAAAACAGTGCCTCCCCACTATCCTGTGGTGTGTTGCCCCACTTCGGGTCCTC
  AGATGTGTAGCAAGCGGCCAGCCCGAGGGAGAGCCACACTTGGGAGCCAGCGAAAACGCC
  GGAAGTCAGTGACACCAGATCCCAAGGAGAAGCAGACATGTGACATCAGACTGCGGGTTC
  GGGCTGAATACTGCCAGCATGAGACTGCTCTGCAGGGCAATGTCTTTCTCTAACAGCAGG
  ACCCACTTGAGCGCCAGTTTGAGCGCTTTAACCAGCCCACACATNNCTCAGTCCCGGGAC
  CTGGGCTCCATCATCTGTGACATCAAGNNTCTCTGAGCTACCTACTCGAGCATTCTGCGT
  GACTACATCATGGCTCTTATTAGAGCACTTNAAGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_032998 unedited
  GGGGNGGGGGGGNNNNNNNNNNNNTNNNNNNNNNAANNTTTTACTNTGNACCGCGGNCCG
  CATACNAGNGATCGGTTTTTTTTTTTTTTTTTTTATAGTCATTGTTTATTTCATGGAAAC
  TGAAGTTCTGCTGAGGGCTGAGCAGCACTGGCATTGAAAAAATAATAATCATAAAGTCTG
  TGTCTGGACATCGCCTTTGGGAACTAGAAGGGGAGTTGGTATTGTACCAGCTGGACTAAG
  CTCCAGTTCTAGACCTCCTGGCTCATTCAACATGCCTCCCTACCTAAATAAAAGTGCAAC
  ACTCAGTGCATGTCCCAGCCCCATTCTCCCAAGCATGGGAGTGGGCGTAGGAGTGGAGGA
  GGGGGAAGGAAAAAGGAATTACTTCACTTACACCTATGATGCCCTTTGCCCAAGCCAGAA
  GAAAGCAAAGGGGAAAAGGGCTGCAGGGTACATTATTTATTTTCACTTGAACATGGAAAG
  AAAGTGTCACACTCCCCCTTCCCCTTTATAGGGGGAGTGTATTTTAATCAGCAACCTCTT
  CTCCATCCACCCTGTGTATGTGTGTACACATATACCACCACAGTTGGGAGGCATGACTAG
  GCTGACCCAGTCTTATCTGTTCCTCCTTTGAAGAGGGTTTGACAAATGGGAAAAAGGAAG
  GAGCCACATCANGCAGAGGTTTCAAGCCATGGAATGGANGAAAAGCNGCANAGAGGAGCA
  NCACCAGAGGCCAGGAGAGAGTGGAAAAGGCCACAGCTNGNTTTTAAAAAATNCTATNAT
  TNGGAAGAGGGNTGCGGATAATTTTCAAATACACTTCAGAGTCCACTTTCACATAGCTCC
  CTTACTACAGNCCTTTGGTTNTTTAGACAAATTTAAGAGCTCTCATAAGCCAGAAGTATT
  GATAACTCCTAGTGCATCCAAAAAAAGGGTTCACATCATCCCTACAAAGACTTGTGCTGT
  AAACTTTGCTCCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_032998
• ORF Size: 957 bp
• Insert Size: 2100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_032998.1, NP_127491.1
• RefSeq Size: 2261
• RefSeq ORF: 957
• Locus ID: 9191
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) uses an alternate in-frame splice junction compared to variant 5. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 1, 3, and 4 all encode the same isoform (b).