Cytochrome P450 17A1 (CYP17A1) (NM_000102) Human Untagged Clone

CAT#: SC102224

CYP17A1 (untagged)-Human cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1)


  "NM_000102" in other vectors (6)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CYP17A1
Synonyms CPT7; CYP17; P450C17; S17AH
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_000102 edited
ATAGGGCGGCCGCGAATTCGGCACGAGACTGCTGTCTATCTTGCCTGCCGGCACCCAGCC
ACCATGTGGGAGCTCGTGGCTCTCTTGCTGCTTACCCTAGCTTATTTGTTTTGGCCCAAG
AGAAGGTGCCCTGGTGCCAAGTACCCCAAGAGCCTCCTGTCCCTGCCCCTGGTGGGCAGC
CTGCCATTCCTCCCCAGACACGGCCATATGCATAACAACTTCTTCAAGCTGCAGAAAAAA
TATGGCCCCATCTATTCGGTTCGTATGGGCACCAAGACTACAGTGATTGTCGGCCACCAC
CAGCTGGCCAAGGAGGTGCTTATTAAGAAGGGCAAGGACTTCTCTGGGCGGCCTCAAATG
GCAACTCTAGACATCGCGTCCAACAACCGTAAGGGTATCGCCTTCGCTGACTCTGGCGCA
CACTGGCAGCTGCATCGAAGGCTGGCGATGGCCACCTTTGCCCTGTTCAAGGATGGCGAT
CAGAAGCTGGAGAAGATCATTTGTCAGGAAATCAGTACATTGTGTGATATGCTGGCCACC
CACAACGGACAGTCCATAGACATCTCCTTTCCTGTCTTCGTGGCGGTAACCAATGTCATC
TCCTTGATCTGCTTCAATACCTCCTACAAGAATGGGGACCCTGAGTTGAATGTCATACAG
AATTACAATGAAGGCATCATAGACAACCTGAGCAAAGACAGCCTGGTGGACCTAGTCCCC
TGGTTGAAGATTTTCCCCAACAAAACCCTGGAAAAATTAAAGAGCCATGTTAAAATACGA
AATGATCTGCTGAATAAAATACTTGAAAATTACAAGGAGAAATTCCGGAGTGACTCTATC
ACCAACATGCTGGACACACTGATGCAAGCCAAGATGAACTCAGATAATGGCAATGCTGGC
CCAGATCAAGACTCAGAGCTGCTTTCAGATAACCACATTCTCACCACCATAGGGGACATC
TTTGGGGCTGGCGTGGAGACCACCACCTCTGTGGTTAAATGGACCCTGGCCTTCCTGCTG
CACAATCCTCAGGTGAAGAAGAAGCTCTACGAGGAGATTGACCAGAATGTGGGTTTCAGC
CGCACACCAACTATCAGTGACCGTAACCGTCTCCTCCTGCTGGAGGCCACCATCCGAGAG
GTGCTTCGCCTCAGGCCCGTGGCCCCTATGCTCATCCCCCACAAGGCCAACGTTGACTCC
AGCATCGGTGAGTTTGCTGTGGACAAGGGCACAGAAGTTATCATCAATCTGTGGGCGCTG
CATCACAATGAGAAGGAGTGGCACCAGCCGGATCAGTTCATGCCTGAGCGTTTCTTGAAT
CCAGCGGGGACCCAGCTCATCTCACCGTCAGTAAGCTATTTGCCCTTCGGAGCAGGACCT
CGCTCCTGTATAGGTGAGATCCTGGCCCGCCAGGAGCTCTTCCTCATCATGGCCTGGCTG
CTGCAGAGGTTCGACCTGGAGGTGCCAGATGATGGGCAGCTGCCCTCCCTGGAAGGCATC
CCCAAGGTGGTCTTTCTGATCGACTCTTTCAAAGTGAAGATCAAGGTGCGCCAGGCCTGG
AGGGAAGCCCAGGCTGAGGGTAGCACCTAAAGGCTGTAACTCACAGCCCCTGTCCACCCT
ATGTGGCCCCACAACACAGATTTAGAGATACAACCCCCCACCCTTCTCCGCCATTCTTCC
CTACTCCCAACCCACTCTGCCTTCTTTTTCAGCTTGTGGCAATGCCAGTGATGTGCATAA
ACAGTTTTTTTTTTTCCAAAAAAAAGTGAAAGGCAGCCTGGGAATGAACATTGTTAGTTC
TATCTTGGCCTTCATTGGAGTGATTCTGCTGCTGGTGGATATGTGCATCAATGGGGTAGC
TG
>OriGene 5' read for NM_000102 unedited
ATTATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGACTGCTGTCT
ATCTTGCCTGCCGGCACCCAGCCACCATGTGGGAGCTCGTGGCTCTCTTGCTGCTTACCC
TAGCTTATTTGTTTTGGCCCAAGAGAAGGTGCCCTGGTGCCAAGTACCCCAAGAGCCTCC
TGTCCCTGCCCCTGGTGGGCAGCCTGCCATTCCTCCCCAGACACGGCCATATGCATAACA
ACTTCTTCAAGCTGCAGAAAAAATATGGCCCCATCTATTCGGTTCGTATGGGCACCAAGA
CTACAGTGATTGTCGGCCACCACCAGCTGGCCAAGGAGGTGCTTATTAAGAAGGGCAAGG
ACTTCTCTGGGCGGCCTCAAATGGCAACTCTAGACATCGCGTCCAACAACCGTAAGGGTA
TCGCCTTCGCTGACTCTGGCGCACACTGGCAGCTGCATCGAAGGCTGGCGATGGCCACCT
TTGCCCTGTTCAAGGATGGCGATCAGAAGCTGGAGAAGATCATTTGTCAGGAAATCAGTA
CATTGTGTGATATGCTGGCCACCCACAACGGACAGTCCATAGACATCTCCTTTCCTGTCT
TCGTGGCGGTAACCAATGTCATCTCCTTGATCTGCTTCAATACCTCCTACAAGAATGGGG
ACCCTGAGTTGAATGTCATACAGAATTACAATGAAGGCATCATAGACAACCTGAGCAAAG
ACAGCCTGGTGGACCTAGTCCCNCTGTTGAAAGATTTCCCCACAAAACCCTGNAAAAATA
AAGAGCCATGTAAAATACGAATGATCTGCTGAATAAAATACTGANAATACAGGAGAAANT
NCCGATGACTCTTCACCACATGCTGGAACACTGATGCAGCCCAAGATGACTCANATATGG
CATGCTGGCCAGATCAGATCAAACTGTTTCGATACCACATCTACACATAGGGACTT
>OriGene 3' read for NM_000102 unedited
CTATGGAACGGCGGCCGCAATCTAGGATCGAGTTTTNNNNNNTTTTTTTTTTTTTTTTTT
TTTTTTTTTGGGNNCTAAGGACCTTTTATTAAGGAAAAAGTAATTTGAACAGAAACATTT
TTAACTTTAAAAAAGTTGCAGAATCATTTTTCAGTCCTCTGATCCTTCACCTTTGCCAGC
ATGTAATAGTGGTAATGTAGGAAAAAACAGTGAAGGGAGATACAGCCATTATTAGCGACC
AACCTAAAAACAAATTTCAAACACAGTTTTTAAAGACTAGAAATCATTGTAGACAATAAA
AGACATTTTTTTAAAAAATTTTTGCAAGGGGTTTTTCTCCATGAAATTAAACTGATACCC
CTTTTTCTTTTACTATTTAGGGGCATTAACTGAGTAGTTGTTGCATCTGGGAGGAGCTGA
AAAAAACCCTGGGGTCACAGGGTTGCTTTCATACATATTTGGAATAACCAGGACAGACAT
ATTGGTTGGGGGGTTTGCTTGGTTGGCAAAATGGGCTGTGGCACAAGCTACGAAGAACTC
CAAGAGGGAGAAGATCATCAGCGTGGCTGAAATGCCTTTTCCAGAAAGCACGGCCCAGTA
GTCTTGGCCAGCTACCCCATTGATGCACATATCCACCAGCAGCAGAATCACTCCAATGAA
GGCCAAGATAGAACTAACAATGTTCATTCCCAGGCTGGCTTTTACTTTTTTTTGGGAAAA
AAAAACTGTTTTGCACATCACTGGCATTGCCACAAGCTGAAAAAAAAGGCANAATGGTTN
GGGAGTAGGGAAAAATGGCGGGAAAAGGTGGGGGGGTTGTATCTCTAAATTGGTGTGTGG
GGCCCCATAGGGTTGACAGGGGCTTGGGAGTACAGCCTTTAGGGCTACCCTCACCTGGGC
TTNCCTCAGGCTGGCGCCCTTGACTNACTTTGAAGAACATCACAAAACCCCTGGGGAGCT
TCCAGAAGGCACTGCCATAA
Restriction Sites Please inquire     
ACCN NM_000102
Insert Size 2500 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000102.2, NP_000093.1
RefSeq Size 1755 bp
RefSeq ORF 1527 bp
Locus ID 1586
Cytogenetics 10q24.32
Domains p450
Protein Families Druggable Genome, P450
Protein Pathways C21-Steroid hormone metabolism, Metabolic pathways
Gene Summary 'This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]'

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