STING (TMEM173) (AK095896) Human Untagged Clone

CAT#: SC102596

(untagged)-Human cDNA FLJ38577 fis, clone HCHON2007650


Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol TMEM173
Synonyms ERIS|MITA|MPYS|NET23|SAVI|STING|hMITA|hSTING
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for AK095896, the custom clone sequence may differ by one or more nucleotides


AAACCAGAAGAAAAATATGAGACGGGGAATCATCGTGTGATGTGTGTGCTGCCTTTGGCTGAGTGTGTGG
AGTCCTGCTCAGGTGTTAGGTACAGTGTGTTTGATCGTGGTGGCTTGAGGGGAACCCGCTGTTCAGAGCT
GTGACTGCGGCTGCACTCAGAGAAGCTGCCCTTGGCTGCTCGTAGCGCCGGGCCTTCTCTCCTCGTCATC
ATCCAGAGCAGCCAGTGTCCGGGAGGCAGAAGATGCCCCACTCCAGCCTGCATCCATCCATCCCGTGTCC
CAGGGGTCACGGGGCCCAGAAGGCAGCCTTGGTTCTGCTGAGTGCCTGCCTGGTGACCCTTTGGGGGCTA
GGAGAGCCACCAGAGCACACTCTCCGGTACCTGGTCCTCCACCTAGCCTCCCTGCAGCTGGGACTGCTGT
TAAACGGGGTCTGCAGCCTGGCTGAGGAGCTGCGCCACATCCACTCCAGGTGACTCACTGCAGTACCCAG
GGACGGGGTATCCAACGTGTGTCACTCCCTTGATGCCTAGCCCTGCCCCTCCTTGAACCTCTCTGGCTGA
GCTGGGCTGGGGGCTGGGGTCTGGGGTCTGGCTGTCACTCACAGGTACCGGGGCAGCTACTGGAGGACTG
TGCGGGCCTGCCTGGGCTGCCCCCTCCGCCGTGGGGCCCTGTTGCTGCTGTCCATCTATTTCTACTACTC
CCTCCCAAATGCGGTCGGCCCGCCCTTCACTTGGATGCTTGCCCTCCTGGGCCTCTCGCAGGCACTGAAC
ATCCTCCTGGGCCTCAAGGTATGACACAGGGGGAGGTAGAAGCTCTGGCCAAGTGGTGGCTGTGGCTGGT
GTGACCTGCCCTGAGCTGAGTACTGGGAGTGGGACTGGTTTAAAGGCTGGAGTCCATGGAGTAGAACCTA
TAATGTCCTGGAACAGTGGGTTTGGCAATGGCAAAAGAGGGATCAAGTCAGGAGCAGGTTGGGAAGCCTT
GGAGGAGGAGGAGGAGTTCTCTGGGTGTCCTTGATGGAGGCCCCCCAGCCACATCCTGCTGTCCACAGGG
CCTGGCCCCAGCTGAGATCTCTGCAGTGTGTGAAAAAGGGAATTTCAACGTGGCCCATGGGCTGGCATGG
TCATATTACATCGGATATCTGCGGCTGATCCTGCCAGCCTGGAGTACAGTGGTGACAAGATCTCAGCTCA
CTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTGAGCCTCTTGAATAGCTAGGATTACAGGC
ACGTGCCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAGACAATGTTTCACCATGTTGCCCAGGCTA
GTCTCAAACTCCTGACCTCAAATGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGATTACAGGCGTGAGC
CACTGTGCCTGCCCTAAGCCTGTGTGTTTTATTCTTCTGACTTGCAGGCTAAAGCGGCAGCTCTTCCATA
TCTCATTGCTATCTCCTAGGGCTTCCGCTAGGAGACTGATCTGGGGCTAGAGGCCTCCCTCTGTGCACAC
GAGAATGCTGGAAATGTCACCTCTCAGGGCTCTGCCTGCCTCTCAGCCCTGAAAGCCATGGTGGAAAGGG
GTGGCGCTGACATAGACATCTGAGGAAAGAAGTGAGGGAGGGTAAAGGGTGGTGCAGTAAGAGGAGGGGT
GGGGAGGGCTTTTGGAGGCGCTGCCCCTCCTGGCCTCCTGTACAATGAGAGTGCACTGGACTCTCCATTC
TCTGGCACCCACACACTGCGGGGGCCAATGACCTGGGTCTCACTCCTGAATCAGGTGGGAGATAGGGTTA
GCAGGAATAACTTCTTGGGCTTCCCTGCCTCAGAGCTCCAGGCCCGGATTCGAACTTACAATCAGCATTA
CAACAACCTGCTACGGGGTGCAGTGAGCCAGCGGCTGTATATTCTCCTCCCATTGGACTGTGGGGTGCCT
GATAACCTGAGTATGGCTGACCCCAACATTCGCTTCCTGGATAAACTGCCCCAGCAGACCGGTGACCGTG
CTGGCATCAAGGATCGGGTTTACAGCAACAGCATCTATGAGCTTCTGGAGAACGGGCAGCGGGCGGGCAC
CTGTGTCCTGGAGTACGCCACCCCCTTGCAGACTTTGTTTGCCATGTCACAATACAGTCAAGCTGGCTTT
AGCCGGGAGGATAGGCTTGAGCAGGCCAAACTCTTCTGCCGGACACTTGAGGACATCCTGGCAGATGCCC
CTGAGTCTCAGAACAACTGCCGCCTCATTGCCTACCAGGAACCTGCAGATGACAGCAGCTTCTCGCTGTC
CCAGGAGGTTCTCCGGCACCTGCGGCAGGAGGAAAAGGAAGAGGTTACTGTGGGCAGCTTGAAGACCTCA
GCGGTGCCCAGTACCTCCACGATGTCCCAAGAGCCTGAGCTCCTCATCAGTGGAATGGAAAAGCCCCTCC
CTCTCCGCACGGATTTCTCTTGAGACCCAGGGTCACCAGGCCAGAGCCTCCAGTGGTCTCCAAGCCTCTG
GACTGGGGGCTCTCTTCAGTGGCTGAATGTCCAGCAGAGCTATTTCCTTCCACAGGGGGCCTTGCAGGGA
AGGGTCCAGGACTTGACATCTTAAGATGCGTCTTGTCCCCTTGGGCCAGTCATTTCCCCTCTCTGAGCCT
CGGTGTCTTCAACCTGTGAAATGGGATCATAATCACTGCCTTACCTCCCTCACGGTTGTTGTGAGGACTG
AGTGTGTGGAAGTTTTTCATAAACTTTGGATGCTAGTGTACTTAGGGGGTGTGCCAGGTGTCTTTCATGG
GGCCTTCCAGACCCACTCCCCACCCTTCTCCCCTTCCTTTGCCCGGGGACGCCGAACTCTCTCAATGGTA
TCAACAGGCTCCTTCGCCCTCTGGCTCCTGGTCATGTTCCATTATTGGGGAGCCCCAGCAGAAGAATGGA
GAGGAGGAGGAGGCTGAGTTTGGGGTATTGAATCCCCCGGCTCCCACCCTGCAGCATCAAGGTTGCTATG
GACTCTCCTGCCGGGCAACTCTTGCGTAATCATGACTATCTCTAGGATTCTGGCACCACTTCCTTCCCTG
GCCCCTTAAGCCTAGCTGTGTATCGGCACCCCCACCCCACTAGAGTACTCCCTCTCACTTGCGGTTTCCT
TATACTCCACCCCTTTCTCAACGGTCCTTTTTTAAAGCACATCTCAGATT


>OriGene 5' read for AK095896 unedited
AAATTTTGTATACGACGTCACTATAGGGCGGCCGCGAATTCGCACGAGGACATAGACATC
TGAGGAAAGAATGAGGGAGGGTAAAGGGTGGTGCAGTAAGAGGAGGGGTGGGGAGGGCTT
TTGGAGGCGCTGCCCCTCCTGGCCTCCTGTACAATGAGAGTGCACTGGACTCTCCATTCT
CTGGCACCCACACACTGCGGGGGCCAATGACCTGGGTCTCACTCCTGAATCAGGTGGGAG
ATAGGGTTAGCAGGAATAACTTCTTGGGCTTCCCTGCCTCAGAGCTCCAGGCCCGGATTC
GAACTTACAATCAGCATTACAACAACCTGCTACGGGGTGCAGTGAGCCAGCGGCTGTATA
TTCTCCTCCCATTGGACTGTGGGGTGCCTGATAACCTGAGTATGGCTGACCCCAACATTC
GCTTCCTGGATAAACTGCCCCAGCAGACCGGTGACCATGCTGGCATCAAGGATCGGGTTT
ACAGCAACAGCATCTATGAGCTTCTGGAGAACGGGCAGCGGGCGGGCACCTGTGTCCTGG
AGTACGCCACCCCCTTGCAGACTTTGTTTGCCATGTCACAATACAGTCAAGCTGGCTTTA
GCCGGGAGGATAGGCTTGAGCAGGCCAAACTCTTCTGCCGGACACTTGAGGACATCCTGG
CAGATGCCCCTGAGTCTCAGAACAACTGCCGCCTCATTGCCTACCAGGAACCTGCAGATG
ACAGCAGCTTCTCGCTGTCCCAGGAAGTTCTCCGGCACCTGCNGCANGANGAAAANGGAA
GAGTTACTGTGGGCAGCTTGAAGACCCTCAGCGTGCCCAGTACCTNCACGATGTCCCAAG
AGCCCTGAGCTCTCATCAGTGGAATGGNAAAAGCCCTNCCTCTCTNACNGATTCTCTTGA
GACCAGGGTACCAGCCAGAGCCTNCAGTGTCTCCAGCTCTGACTGGGGCTCTCTCATGGC
TGAATGTCACANACTATTCCTTCAGGGGNCTGCAGGGA
>OriGene 3' read for AK095896 unedited
GAATACTTGTTACGCGGCCGCAATCCACGATCGATTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTAATCTGGAAAGTGCTTTAAAAAAGACCGTTTAAAAAGGGT
GGAGTATAAGGAAACCCCAAGTGAAAGGGAGTACTCTATTGGGGTGGGGGTCCCCATACA
CAACTAGGCTTAAGGGGCCAGGGAAAGAAATGGTGCCAAAATCCTAGAAATAGTCATGAT
TACCCAAGAATTGCCCGGCCGGAAATTCCATACCACCCTTTATTCTCCCAGGTGGGACCC
CGGGGAATCAATTCCCCAAACTCATCCTCCTCCTCCTCTCCATTTTTCTGCTGGGGCTCC
CCAATAATGGAACATTGACCAGGACCCAAGGCCCTAAAGACCCTGTTTACCCCATTGAAA
GAGTTCGGCGTCCCGGGGACAAGGAAGGGGAAAAGGGGGGCGAGTGCGCTCCTAGACACT
ATGTAACGCACCACGGACATACCCCAGCACAAGTCCTACACAAACCTACAAGTCTAAATG
TGACCTACTCCACGCGGAAGAGGGGAACACTGGGAGGAGTGAGAGGAGTGAATCACCAGA
ATCAGCACACCACAACAGCACGACGAACAAACAGGACAGAGTGACGCGAGCGGTGAACAG
CAAGGGGCGCGAAACCGCAAACAAAAAAACCCCACACATACAGGAGAAAACGCGAACGAA
CAAGAGTACAAAACAAAGACACAAGAACAGGAAGAAAAATAAAGTATACCGAGCACGTAG
CATCGACATTACGGAGTTACGTAAACTTGCCCACATCCTGGTAAGATATGTTTAATATTC
GGTGATTCCGCAAATTTTCACCCGCCGGGCGGCACAGGCTCCCACCACCCGCCCCGACGA
ACGGAAAGCAGCGCAGAACGGGCCAA
Restriction Sites NotI-NotI     
ACCN AK095896
ORF Size 3200 bp
Insert Size 1750
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq AK095896.1
RefSeq Size 3200
RefSeq ORF 3200
Locus ID 340061
Protein Pathways Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway
Gene Summary This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

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