STING (TMEM173) (AK095896) Human Untagged Clone
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | TMEM173 |
Synonyms | ERIS|MITA|MPYS|NET23|SAVI|STING|hMITA|hSTING |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for AK095896, the custom clone sequence may differ by one or more nucleotides
AAACCAGAAGAAAAATATGAGACGGGGAATCATCGTGTGATGTGTGTGCTGCCTTTGGCTGAGTGTGTGG AGTCCTGCTCAGGTGTTAGGTACAGTGTGTTTGATCGTGGTGGCTTGAGGGGAACCCGCTGTTCAGAGCT GTGACTGCGGCTGCACTCAGAGAAGCTGCCCTTGGCTGCTCGTAGCGCCGGGCCTTCTCTCCTCGTCATC ATCCAGAGCAGCCAGTGTCCGGGAGGCAGAAGATGCCCCACTCCAGCCTGCATCCATCCATCCCGTGTCC CAGGGGTCACGGGGCCCAGAAGGCAGCCTTGGTTCTGCTGAGTGCCTGCCTGGTGACCCTTTGGGGGCTA GGAGAGCCACCAGAGCACACTCTCCGGTACCTGGTCCTCCACCTAGCCTCCCTGCAGCTGGGACTGCTGT TAAACGGGGTCTGCAGCCTGGCTGAGGAGCTGCGCCACATCCACTCCAGGTGACTCACTGCAGTACCCAG GGACGGGGTATCCAACGTGTGTCACTCCCTTGATGCCTAGCCCTGCCCCTCCTTGAACCTCTCTGGCTGA GCTGGGCTGGGGGCTGGGGTCTGGGGTCTGGCTGTCACTCACAGGTACCGGGGCAGCTACTGGAGGACTG TGCGGGCCTGCCTGGGCTGCCCCCTCCGCCGTGGGGCCCTGTTGCTGCTGTCCATCTATTTCTACTACTC CCTCCCAAATGCGGTCGGCCCGCCCTTCACTTGGATGCTTGCCCTCCTGGGCCTCTCGCAGGCACTGAAC ATCCTCCTGGGCCTCAAGGTATGACACAGGGGGAGGTAGAAGCTCTGGCCAAGTGGTGGCTGTGGCTGGT GTGACCTGCCCTGAGCTGAGTACTGGGAGTGGGACTGGTTTAAAGGCTGGAGTCCATGGAGTAGAACCTA TAATGTCCTGGAACAGTGGGTTTGGCAATGGCAAAAGAGGGATCAAGTCAGGAGCAGGTTGGGAAGCCTT GGAGGAGGAGGAGGAGTTCTCTGGGTGTCCTTGATGGAGGCCCCCCAGCCACATCCTGCTGTCCACAGGG CCTGGCCCCAGCTGAGATCTCTGCAGTGTGTGAAAAAGGGAATTTCAACGTGGCCCATGGGCTGGCATGG TCATATTACATCGGATATCTGCGGCTGATCCTGCCAGCCTGGAGTACAGTGGTGACAAGATCTCAGCTCA CTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTGAGCCTCTTGAATAGCTAGGATTACAGGC ACGTGCCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAGACAATGTTTCACCATGTTGCCCAGGCTA GTCTCAAACTCCTGACCTCAAATGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGATTACAGGCGTGAGC CACTGTGCCTGCCCTAAGCCTGTGTGTTTTATTCTTCTGACTTGCAGGCTAAAGCGGCAGCTCTTCCATA TCTCATTGCTATCTCCTAGGGCTTCCGCTAGGAGACTGATCTGGGGCTAGAGGCCTCCCTCTGTGCACAC GAGAATGCTGGAAATGTCACCTCTCAGGGCTCTGCCTGCCTCTCAGCCCTGAAAGCCATGGTGGAAAGGG GTGGCGCTGACATAGACATCTGAGGAAAGAAGTGAGGGAGGGTAAAGGGTGGTGCAGTAAGAGGAGGGGT GGGGAGGGCTTTTGGAGGCGCTGCCCCTCCTGGCCTCCTGTACAATGAGAGTGCACTGGACTCTCCATTC TCTGGCACCCACACACTGCGGGGGCCAATGACCTGGGTCTCACTCCTGAATCAGGTGGGAGATAGGGTTA GCAGGAATAACTTCTTGGGCTTCCCTGCCTCAGAGCTCCAGGCCCGGATTCGAACTTACAATCAGCATTA CAACAACCTGCTACGGGGTGCAGTGAGCCAGCGGCTGTATATTCTCCTCCCATTGGACTGTGGGGTGCCT GATAACCTGAGTATGGCTGACCCCAACATTCGCTTCCTGGATAAACTGCCCCAGCAGACCGGTGACCGTG CTGGCATCAAGGATCGGGTTTACAGCAACAGCATCTATGAGCTTCTGGAGAACGGGCAGCGGGCGGGCAC CTGTGTCCTGGAGTACGCCACCCCCTTGCAGACTTTGTTTGCCATGTCACAATACAGTCAAGCTGGCTTT AGCCGGGAGGATAGGCTTGAGCAGGCCAAACTCTTCTGCCGGACACTTGAGGACATCCTGGCAGATGCCC CTGAGTCTCAGAACAACTGCCGCCTCATTGCCTACCAGGAACCTGCAGATGACAGCAGCTTCTCGCTGTC CCAGGAGGTTCTCCGGCACCTGCGGCAGGAGGAAAAGGAAGAGGTTACTGTGGGCAGCTTGAAGACCTCA GCGGTGCCCAGTACCTCCACGATGTCCCAAGAGCCTGAGCTCCTCATCAGTGGAATGGAAAAGCCCCTCC CTCTCCGCACGGATTTCTCTTGAGACCCAGGGTCACCAGGCCAGAGCCTCCAGTGGTCTCCAAGCCTCTG GACTGGGGGCTCTCTTCAGTGGCTGAATGTCCAGCAGAGCTATTTCCTTCCACAGGGGGCCTTGCAGGGA AGGGTCCAGGACTTGACATCTTAAGATGCGTCTTGTCCCCTTGGGCCAGTCATTTCCCCTCTCTGAGCCT CGGTGTCTTCAACCTGTGAAATGGGATCATAATCACTGCCTTACCTCCCTCACGGTTGTTGTGAGGACTG AGTGTGTGGAAGTTTTTCATAAACTTTGGATGCTAGTGTACTTAGGGGGTGTGCCAGGTGTCTTTCATGG GGCCTTCCAGACCCACTCCCCACCCTTCTCCCCTTCCTTTGCCCGGGGACGCCGAACTCTCTCAATGGTA TCAACAGGCTCCTTCGCCCTCTGGCTCCTGGTCATGTTCCATTATTGGGGAGCCCCAGCAGAAGAATGGA GAGGAGGAGGAGGCTGAGTTTGGGGTATTGAATCCCCCGGCTCCCACCCTGCAGCATCAAGGTTGCTATG GACTCTCCTGCCGGGCAACTCTTGCGTAATCATGACTATCTCTAGGATTCTGGCACCACTTCCTTCCCTG GCCCCTTAAGCCTAGCTGTGTATCGGCACCCCCACCCCACTAGAGTACTCCCTCTCACTTGCGGTTTCCT TATACTCCACCCCTTTCTCAACGGTCCTTTTTTAAAGCACATCTCAGATT >OriGene 5' read for AK095896 unedited
AAATTTTGTATACGACGTCACTATAGGGCGGCCGCGAATTCGCACGAGGACATAGACATC TGAGGAAAGAATGAGGGAGGGTAAAGGGTGGTGCAGTAAGAGGAGGGGTGGGGAGGGCTT TTGGAGGCGCTGCCCCTCCTGGCCTCCTGTACAATGAGAGTGCACTGGACTCTCCATTCT CTGGCACCCACACACTGCGGGGGCCAATGACCTGGGTCTCACTCCTGAATCAGGTGGGAG ATAGGGTTAGCAGGAATAACTTCTTGGGCTTCCCTGCCTCAGAGCTCCAGGCCCGGATTC GAACTTACAATCAGCATTACAACAACCTGCTACGGGGTGCAGTGAGCCAGCGGCTGTATA TTCTCCTCCCATTGGACTGTGGGGTGCCTGATAACCTGAGTATGGCTGACCCCAACATTC GCTTCCTGGATAAACTGCCCCAGCAGACCGGTGACCATGCTGGCATCAAGGATCGGGTTT ACAGCAACAGCATCTATGAGCTTCTGGAGAACGGGCAGCGGGCGGGCACCTGTGTCCTGG AGTACGCCACCCCCTTGCAGACTTTGTTTGCCATGTCACAATACAGTCAAGCTGGCTTTA GCCGGGAGGATAGGCTTGAGCAGGCCAAACTCTTCTGCCGGACACTTGAGGACATCCTGG CAGATGCCCCTGAGTCTCAGAACAACTGCCGCCTCATTGCCTACCAGGAACCTGCAGATG ACAGCAGCTTCTCGCTGTCCCAGGAAGTTCTCCGGCACCTGCNGCANGANGAAAANGGAA GAGTTACTGTGGGCAGCTTGAAGACCCTCAGCGTGCCCAGTACCTNCACGATGTCCCAAG AGCCCTGAGCTCTCATCAGTGGAATGGNAAAAGCCCTNCCTCTCTNACNGATTCTCTTGA GACCAGGGTACCAGCCAGAGCCTNCAGTGTCTCCAGCTCTGACTGGGGCTCTCTCATGGC TGAATGTCACANACTATTCCTTCAGGGGNCTGCAGGGA >OriGene 3' read for AK095896 unedited
GAATACTTGTTACGCGGCCGCAATCCACGATCGATTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTAATCTGGAAAGTGCTTTAAAAAAGACCGTTTAAAAAGGGT GGAGTATAAGGAAACCCCAAGTGAAAGGGAGTACTCTATTGGGGTGGGGGTCCCCATACA CAACTAGGCTTAAGGGGCCAGGGAAAGAAATGGTGCCAAAATCCTAGAAATAGTCATGAT TACCCAAGAATTGCCCGGCCGGAAATTCCATACCACCCTTTATTCTCCCAGGTGGGACCC CGGGGAATCAATTCCCCAAACTCATCCTCCTCCTCCTCTCCATTTTTCTGCTGGGGCTCC CCAATAATGGAACATTGACCAGGACCCAAGGCCCTAAAGACCCTGTTTACCCCATTGAAA GAGTTCGGCGTCCCGGGGACAAGGAAGGGGAAAAGGGGGGCGAGTGCGCTCCTAGACACT ATGTAACGCACCACGGACATACCCCAGCACAAGTCCTACACAAACCTACAAGTCTAAATG TGACCTACTCCACGCGGAAGAGGGGAACACTGGGAGGAGTGAGAGGAGTGAATCACCAGA ATCAGCACACCACAACAGCACGACGAACAAACAGGACAGAGTGACGCGAGCGGTGAACAG CAAGGGGCGCGAAACCGCAAACAAAAAAACCCCACACATACAGGAGAAAACGCGAACGAA CAAGAGTACAAAACAAAGACACAAGAACAGGAAGAAAAATAAAGTATACCGAGCACGTAG CATCGACATTACGGAGTTACGTAAACTTGCCCACATCCTGGTAAGATATGTTTAATATTC GGTGATTCCGCAAATTTTCACCCGCCGGGCGGCACAGGCTCCCACCACCCGCCCCGACGA ACGGAAAGCAGCGCAGAACGGGCCAA |
Restriction Sites | NotI-NotI |
ACCN | AK095896 |
ORF Size | 3200 bp |
Insert Size | 1750 |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
Reference Data | |
RefSeq | AK095896.1 |
RefSeq Size | 3200 |
RefSeq ORF | 3200 |
Locus ID | 340061 |
Protein Pathways | Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway |
Gene Summary | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
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