KIDINS220 (AK022873) Human Untagged Clone

CAT#: SC102707

(untagged)-Human cDNA FLJ12811 fis, clone NT2RP2002475

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KIDINS220
• Synonyms: ARMS
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC102707 sequence for AK022873 edited (data generated by NextGen Sequencing)
  ATGCTGCCTCAGTATTGTACCACGATCAAAAAGGCAAACATAAATGGCCGTGTGTTAGCT
  CAGTGTAACATTGATGAGCTGAAGAAAGAGATGAATATGAATTTTGGAGACTGGCACCTT
  TTCAGAAGCACAGTACTAGAAATGAGAAACGCAGAAAGCCACGTGGTCCCTGAAGACCCA
  CGTTTCCTCAGTGAGAGCAGCAGTGGCCCAGCCCCGCACGGTGAGCCTGCTCGCCGCGCT
  TCCCACAACGAGCTGCCTCACACCGAGCTCTCCAGCCAGACGCCCTACACACTCAACTTC
  AGCTTCGAAGAGCTGAACACGCTTGGCCTGGATGAAGGTGCCCCTCGTCACAGTAATCTA
  AGTTGGCAGTCACAAACTCGCAGAACCCCAAGTCTTTCGAGTCTCAATTCCCAGGATTCC
  AGTATTGAAATTTCAAAGCTTACTGATAAGGTGCAGGCCGAGTATAGAGATGCCTATAGA
  GAATACATTGCTCAGATGTCCCAGTTAGAAGGGGGCCCCGGGTCTACAACCATTAGTGGC
  AGATCTTCTCCACATAGCACATATTACATGGGTCAGAGTTCATCAGGGGGCTCTATTCAT
  TCAAACCTAGAGCAAGAAAAGGGGAAGGATAGTGAACCAAAGCCCGATGATGGGAGGAAG
  TCCTTTCTAATGAAGAGGGGAGATGTTATCGATTATTCATCATCAGGGGTTTCCACCAAC
  GATGCTTCCCCCCTGGATCCTATCACTGAAGAAGATGAAAAATCAGATCAGTCAGGCAGT
  AAGCTTCTCCCAGGCAAGAAATCTTCCGAAAGGTCAAGCCTCTTCCAGACAGATTTGAAG
  CTTAAGGGAAGTGGGCTGCGCTATCAAAAACTCCCAAGTGACGAGGATGAATCTGGCACA
  GAAGAATCAGATAACACTCCACTGCTCAAAGATGACAAAGACAGAAAAGCCGAAGGGAAA
  GTAGAGAGAGTGCCGAAGTCTCCAGAACACAGTGCTGAGCCGATCAGAACCTTCATTAAA
  GCCAAAGAGTATTTATCGGATGCGCTCCTTGACAAAAAGGATTCATCGGATTCAGGAGTG
  AGATCCAGTGAAAGTTCTCCCAATCACTCTCTGCACAATGAAGTGGCGGATGACTCCCAG
  CTTGAAAAGGCAAATCTCATAGAGCTGGAAGATGACAGTCACAGCGGAAAGCGGGGAATC
  CCACATAGCCTGAGTGGCCTGCAAGATCCAATTATAGCTCGGATGTCCATTTGTTCAGAA
  GACAAGAAAAGCCCTTCCGAATGCAGCTTGATAGCCAGCAGCCCTGAAGAAAACTGGCCT
  GCATGCCAGAAAGCCTACAACCTGAACCGAACTCCCAGCACCGTGACTCTGAACAACAAT
  AGTGCTCCAGCCAACAGAGCCAATCAAAATTTCGATGAGATGGAGGGAATTAGGGAGACT
  TCTCAAGTCATTTTGAGGCCTAGTTCCAGTCCCAACCCAACCACTATTCAGAATGAGAAT
  CTAAAAAGCATGACACATAAGCGAAGCCAACGTTCAAGTTACACAAGGCTCTCCAAAGAT
  CCTCCGGAGCTCCATGCAGCAGCCTCTTCTGAGAGCACAGGCTTTGGAGAAGAAAGAGAA
  AGCATTCTTTGA
  
  Clone variation with respect to AK022873.1
  1140 t=>g;1153 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for AK022873 unedited
  ATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGCAGGTGGAGTG
  GTGTNCACCACAGCCTCACAGCAGCTATTACAGCGGCATGACGGGCCCTCAGCATCCCTT
  CTACAACAGGCCATTCTTTGCCCCATACCTTTACACGCCAAGGTATTACCCTGGCGGCTC
  CCAACATCTCATCTCACGTCCATCAGTAAAAACGAGTTTGCCCAGAGATCAGAACAATGG
  CCTAGGGTCAGGCCCAGCCCCAGGCCCAGTGGTATTACTGAATTCACTGAATGTGGATGC
  AGTATGTGAGAAGCTGAAACAAATAGAAGGGCTGGACCAGAGTATGCTGCCTCAGTATTG
  TACCACGATCAAAAAGGCAAACATAAATGGCCGTGTGTTAGCTCAGTGTAACATTGATGA
  GCTGAAGAAAGAGATGAATATGAATTTTGGAGACTGGCACCTTTTCAGAAGCACAGTACT
  AGAAATGAGAAACGCAGAAAGCCACGTGGTCCCTGAAGACCCACGTTTCCTCAGTGAGAG
  CAGCAGTGGCCCAGCCCCGCACGGTGAGCCTGCTCGCCGCGCTTCCCACAACGAGCTGCC
  TCACACCGAGCTCTCCAGCCAGACGCCCTACACACTCAACTTCAGCTTCGAAGAGCTGAA
  CACGCTTGGCCTGGATGAAGGTGCCCCTCGTCACAGTAATCTAAGTTGGCAGTCACAAAC
  TCGCAGAACCCCCAGTCTTTCGAGTCTCAATTCCCAGGATTCCAGTATTGAAATTTCAAA
  GCCTACCTGATAAGTGCANGCCGAGTATAGAGATGCTATAGAGATACATTGCTCAGATGT
  CCATTAGAAGGGGCCCCGGGTCTACACCATTATGGCAGATCTCTCCCATAGACATATTAC
  ATGGTCAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for AK022873 unedited
  NCGGTATATCTATGNACGCGGCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTTGCT
  AAGCTCACTTAGAAAAGTTGGGCACCATTTAAAAGATTGGAGAACAGACCAGGGTGGCTT
  CTTGGGCACAGCTGGATGGTGCTGGAAGCCAGGCCTGGGATTTGGAGAGAAGAGTTTCCG
  ACATATAAACCCACGGAGGTCACCAGCCCTCCCCGCATCTACTCTCCTAACAGCTCAGGA
  CAGCCCCGTCACACTACTGCCAGCCCTGGTGACTCACTTTGTTGGCAATTTTTAAAGCCC
  TCTTCATTATGTACTTCCTACTCTTCAGAACCTCTGTGATAAGCAATACCCCTGCCATAC
  AGAACGCTGGATCTCGGTTTACTCAGCCTCTCCCTGTAGCGTCACAGGCTGTGCACTCAC
  CTAGGTGAGCCCCTAAGAGCAGGGTTTGCTTCTGCTTCACCTAACGCCACGTCTTCCCTC
  AAATGTGTGGTCACCAAATGTTTGCAAAAAGGGTCTCTAGCTTTTTTTCTTTTTGGCACA
  TTAAGCCCTTTAAAATACTTCTGACCTATCTTTATACTCAGATCTCACCTCGTCTCAAAA
  AGTTTTATGGGGTAATGCGCCAATGAAAGGTACAGTAGTATTAGTGAGTTCTGAAGCTTC
  NTATTACAAAGACCACAGAGGCTGGCTGGTGAGCCATGCTTCTCATGCTNCCTTCTGTCA
  CACTGCAGATGTCTCTTTTACCCTCGCCTCATCATCGGTTAGTTATCTGTCAGCAAAATG
  TAAAAAGGTGATGGGGCGTGGATGGAGTCAAAATCCAGACAATTTCTGTCATAAGGGGTA
  CAGTACACCTCTTCTCCTTGGCTTGGTTTTCTCAAAGAAGGCTTCTCTTTCTTTCTCCAA
  GCC
  
• Restriction Sites: NotI-NotI
• ACCN: AK022873
• ORF Size: 1632 bp
• Insert Size: 3000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: AK022873.1, BAB14285.1
• RefSeq Size: 2564
• RefSeq ORF: 1632
• Locus ID: 57498
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Neurotrophin signaling pathway
• Gene Summary: This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]