IGLL1 (BC030984) Human Untagged Clone

CAT#: SC103037

(untagged)-Homo sapiens, clone MGC:32654 IMAGE:4701898, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IGLL1
• Synonyms: IGLV144|V1-16
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC103037 sequence for BC030984 edited (data generated by NextGen Sequencing)
  ATGGCCGGCTTCCCTCTCCTCCTCACCCTCCTCACTCACTGTGCAGGGTCCTGGGCCCAG
  TCTGTGCTGACTCAGCCACCCTCAGCGTCTGGGACCCCCGGGCAGAGGGTCACCATCTCT
  TGTTCTGGAAGCAGCTCCGACATCGGAAGTAATTATGTATACTGGTTCCAGCNNNTCCCA
  GGAACGGCCCCCAAACTCCTCATCTATAAGAATAATCAGCGGCCCTCAGGGGTCCCTGAC
  CGATTCTCTGGCTCCAAGTCTGGCACCTCAGCCTCCCTGGCCATCAGTGGGCTCCGGTCC
  GAGGATGAGGCTGATTATTACTGTGCATCATGGGATGACAGCCTGAGTGNNNNNNNNNNN
  TTCGGCGGAGGGACCAAGCTGACCGTCCTNNGTCAGCCCAAGGCTGCCCCCTCGGTCACT
  CTGTTCCCGCCCTCCTCTGAGGAGCTTCAAGCCAACAAGGCCACACTGGTGTGTCTCATA
  AGTGACTTCTACCCGGGAGCCGTGACAGTGGCCTGGAAGGCAGATAGCAGCCCCGTCAAG
  GCGGGAGTGGAGACCACCACACCCTCCAAACAAAGCAACAACAAGTACGCGGCCAGCAGC
  TACCTGAGCCTGACGCCTGAGCAGTGGAAGTCCCACAGAAGCTACAGCTGCCAGGTCACG
  CATGAAGGGAGCACCGTGGAGAAGACAGTGGCCCCTACAGAATGTTCATAG
  
  Clone variation with respect to BC030984.1
  60 a=>g;94 t=>a;135 g=>c;139 a=>g;167 a=>t;173 a=>n;174 a=>n;175 g=>n;209 g=>a;214 g=>a;328 g=>t;350 t=>n;351 c=>n;352 c=>n;353 a=>n;354 t=>n;355 g=>n;356 t=>n;357 g=>n;358 g=>n;359 t=>n;360 a=>n;378 a=>g;390 c=>n;391 a=>n;429 a=>g;638 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC030984 unedited
  TTTGTAATACGACTTTCTATAGGGCGGCCGCGAATTCGGCACGAGGGACAGGATTCAGGA
  CAATCTCCAGCATGGCCGGCTTCCCTCTCCTCCTCACCCTCCTCACTCACTGTGCAGGGT
  CCTGGGCCCAGTCTGTGCTGACTCAGCCACCCTCAGCGTCTGGGACCCCCGGGCAGAGGG
  TCACCATCTCTTGTTCTGGAAGCAGCTCCGACATCGGAAGTAATTATGTATACTGGTTCC
  AGCAGCTCCCAGGAACGGCCCCCAAACTCCTCATCTATAAGAATAATCAGCGGCCCTCAG
  GGGTCCCTGACCGATTCTCTGGCTCCAAGTCTGGCACCTCAGCCTCCCTGGCCATCAGTG
  GGCTCCGGTCCGAGGATGAGGCTGATTATTACTGTGCATCATGGGATGACAGCCTGAGTG
  CCTGGGTGTTCGGCGGAGGGACCAAGCTGACCGTCCTAGGTCAGCCCAAGGCTGCCCCCT
  CGGTCACTCTGTTCCCGCCCTCCTCTGAGGAGCTTCAAGCCAACAAGGCCACACTGGTGT
  GTCTCATAAGTGACTTCTACCCGGGAGCCGTGACAGTGGCCTGGGAGGCAGATAGCAGCC
  CCGTCAAGGCGGGAGTGGAGACCACCACACCCTCCAAACAAAGCAACAACAAGTACGCGG
  CCAGCAGCTACCTGAGCCTGACGCCTGAGCAGTGGAAGTCCCACAGAAGCTACAGCTGCC
  AGGTCACGCATGAAGGGAGCCACCGTGGAGAAGACCAGTGCCCCCTACAGAATGTTCATA
  GGTTCTCAACCCTCACCCCCCACACGGGAGACTAGAGCTGCAGGATCCCAGGGGAGGGGT
  CTCTCCTCCCACCCCAGGCATCAAGCCCTTCTCCTGCACTCCATAACCCTCAATAATATC
  CTCATTGTCATCCGAAAAAANANANNCNANAAAAAACCCCTACCTGCTTCG
  
• Restriction Sites: NotI-NotI
• ACCN: BC030984
• Insert Size: 1000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC030984.1, AAH30984.1
• RefSeq Size: 924 bp
• RefSeq ORF: 924 bp
• Locus ID: 3543
• Cytogenetics: 22q11.23
• Domains: ig
• Protein Families: Secreted Protein
• Protein Pathways: Primary immunodeficiency
• Gene Summary: 'The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'