MASTL (NM_032844) Human Untagged Clone

CAT#: SC103147

MASTL (untagged)-Human microtubule associated serine/threonine kinase-like (MASTL), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MASTL
• Synonyms: GREATWALL; GW; GWL; MAST-L; THC2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_032844 edited
  ATGGATCCCACCGCGGGAAGCAAGAAGGAGCCTGGAGGAGGCGCGGCGACTGAGGAGGGC
  GTGAATAGGATCGCAGTGCCAAAACCGCCCTCCATTGAGGAATTCAGCATAGTGAAGCCC
  ATTAGCCGGGGCGCCTTCGGGAAAGTGTATCTGGGGCAGAAAGGCGGCAAATTGTATGCA
  GTAAAGGTTGTTAAAAAAGCAGACATGATCAACAAAAATATGACTCATCAGGTCCAAGCT
  GAGAGAGATGCACTGGCACTAAGCAAAAGCCCATTCATTGTCCATTTGTATTATTCACTG
  CAGTCTGCAAACAATGTCTACTTGGTAATGGAATATCTTATTGGGGGAGATGTCAAGTCT
  CTCCTACATATATATGGTTATTTTGATGAAGAGATGGCTGTGAAATATATTTCTGAAGTA
  GCACTGGCTCTAGACTACCTTCACAGACATGGAATCATCCACAGGGACTTGAAACCGGAC
  AATATGCTTATTTCTAATGAGGGTCATATTAAACTGACGGATTTTGGCCTTTCAAAAGTT
  ACTTTGAATAGAGATATTAATATGATGGATATCCTTACAACACCATCAATGGCAAAACCT
  AGACAAGATTATTCAAGAACCCCAGGACAAGTGTTATCGCTTATCAGCTCGTTGGGATTT
  AACACACCAATTGCAGAAAAAAATCAAGACCCTGCAAACATCCTTTCAGCCTGTCTGTCT
  GAAACATCACAGCTTTCTCAAGGACTCGTATGCCCTATGTCTGTAGATCAAAAGGACACT
  ACGCCTTATTCTAGCAAATTACTAAAATCATGTCTTGAAACAGTTGCCTCCAACCCAGGA
  ATGCCTGTGAAGTGTCTAACTTCTAATTTACTCCAGTCTAGGAAAAGGCTGGCCACATCC
  AGTGCCAGTAGTCAATCCCACACCTTCATATCCAGTGTGGAATCAGAATGCCACAGCAGT
  CCCAAATGGGAAAAAGATTGCCAGGAAAGTGATGAAGCATTGGGCCCAACAATGATGAGT
  TGGAATGCAGTTGAAAAGTTATGCGCAAAATCTGCAAATGCCATTGAGACGAAAGGTTTC
  AATAAAAAGGATCTGGAGTTAGCTCTTTCTCCCATTCATAACAGCAGTGCCCTTCCCACC
  ACTGGACGCTCTTGTGTAAACCTTGCTAAAAAATGCTTCTCTGGGGAAGTTTCTTGGGAA
  GCAGTAGAACTGGATGTAAATAATATAAATATGGACACTGACACAAGTCAGTTAGGTTTC
  CATCAGTCAAATCAGTGGGCTGTGGATTCTGGTGGGATATCTGAAGAGCACCTTGGGAAA
  AGAAGTTTAAAAAGAAATTTTGAGTTGGTTGACTCCAGTCCTTGTAAAAAAATTATACAG
  AATAAAAAAACTTGTGTAGAGTATAAGCATAACGAAATGACAAATTGTTATACAAATCAA
  AATACAGGCTTAACAGTTGAAGTGCAGGACCTTAAGCTATCAGTGCACAAAAGTCAACAA
  AATGACTGTGCTAATAAGGAGAACATTGTCAATTCTTTTACTGATAAACAACAAACACCA
  GAAAAATTACCTATACCAATGATAGCAAAAAACCTTATGTGTGAACTCGATGAAGACTGT
  GAAAAGAATAGTAAGAGGGACTACTTAAGTTCTAGTTTTCTATGTTCTGATGATGATAGA
  GCTTCTAAAAATATTTCTATGAACTCTGATTCATCTTTTCCTGGAATTTCTATAATGGAA
  AGTCCATTAGAAAGTCAGCCCTTAGATTCAGATAGAAGCATTAAAGAATCCTCTTTTGAA
  GAATCAAATATTGAAGATCCACTTATTGTAACACCAGATTGCCAAGAAAAGACCTCACCA
  AAAGGTGTCGAGAACCCTGCTGTACAAGAGAGTAACCAAAAAATGTTAGGTCCTCCTTTG
  GAGGTGCTGAAAACGTTAGCCTCTAAAAGAAATGCTGTTGCTTTTCGAAGTTTTAACAGT
  CATATTAATGCATCCAATAACTCAGAACCATCCAGAATGAACATGACTTCTTTAGATGCA
  ATGGATATTTCGTGTGCCTACAGTGGTTCATATCCCATGGCTATAACCCCTACTCAAAAA
  AGAAGATCCTGTATGCCACATCAGACCCCAAATCAGATCAAGTCGGGAACTCCATACCGA
  ACTCCGAAGAGTGTGAGAAGAGGGGTGGCCCCCGTTGATGATGGGCGAATTCTAGGAACC
  CCAGACTACCTTGCACCTGAGCTGTTACTAGGCAGGGCCCATGGTCCTGCGGTAGACTGG
  TGGGCACTTGGAGTTTGCTTGTTTGAATTTCTAACAGGAATTCCCCCTTTCAATGATGAA
  ACACCACAACAAGTATTCCAGAATATTCTGAAAAGAGATATCCCTTGGCCAGAAGGTGAA
  GAAAAGTTATCTGATAATGCTCAAAGTGCAGTAGAAATACTTTTAACCATTGATGATACA
  AAGAGAGCTGGAATGAAAGAGCTAAAACGTCATCCTCTCTTCAGTGATGTGGACTGGGAA
  AATCTGCAGCATCAGACTATGCCTTTCATCCCCCAGCCAGATGATGAAACAGATACCTCC
  TATTTTGAAGCCAGGAATACTGCTCAGCACCTGACCGTATCTGGATTTAGTCTGTAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032844 unedited
  GGATTTTGGTATACGACTTACTATAGGGCGGCNCGCGATTCGGCACGAGGGGAATGGCTG
  CTCGCGGAGGGGCAGTGTACGCGGGGCCGCTGTAGGCTGTCCAGCGATGGATCCCACCGC
  GGGAAGCAAGAAGGAGCCTGGAGGAGGCGCGGCGACTGAGGAGGGCGTGAATAGGATCGC
  AGTGCCAAAACCGCCCTCCATTGAGGAATTCAGCATAGTGAAGCCCATTAGCCGGGGCGC
  CTTCGGGAAAGTGTATCTGGGGCAGAAAGGCGGCAAATTGTATGCAGTAAAGGTTGTTAA
  AAAAGCAGACATGATCAACAAAAATATGACTCATCAGGTCCAAGCTGAGAGAGATGCACT
  GGCACTAAGCAAAAGCCCATTCATTGTCCATTTGTATTATTCACTGCAGTCTGCAAACAA
  TGTCTACTTGGTAATGGAATATCTTATTGGGGGAGATGTCAAGTCTCTCCTACATATATA
  TGGTTATTTTGATGAAGAGATGGCTGTGAAATATATTTCTGAAGTAGCACTGGCTCTAGA
  CTACCTTCACAGACATGGAATCATCCACAGGGACTTGAAACCGGACAATATGCTTATTTC
  TAATGAGGGTCATATTAAACTGACGGATTNTGGCCTTTCANAAGTTACTTTGAATAGAGA
  TATTAATATGATGGATATCCCTTACACACCANTCATGGCANAACCTAGACAAGATATTCA
  AGAACCCCAGGACNAGTGNTATCGCTTATCAGCCTCGTGGGATTTAACACACCNATTGCA
  GAAAAAATCAAGACCCTGCANACATCCTTTTCAGCCTGTCTGTCTGAAACATCACAGCTT
  TCTCAGGGACTCGTATGCCCTATGTCCTGTAGATCAAAGGGACACTACGCCTTTTATCTA
  GCAATACTANAATCATGTCTTGAANCAGNTGCCTNCANCCAGAATGCCTTGTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_032844 unedited
  CCTCATCTTGNACCGCGNNGCCGCATCTAAGATCGAGTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTAGGGGCCTCTAATTTTATTGAGGCTTCAGTTTT
  CATAAAGGGCAATAAACAAAATAAATAGATGAAAAAAGCTTTGAAAATTTATATACAGTT
  TTGAGGTTAAAAAAAATTACTGACTATATTCCTTTCAGCCTTTTAACTTTGGGAAAGCTG
  TAACGTACATTAAAAGCACATTGAACTAGGTTAAATAATGATCTTTCCCCCTTAAATCAA
  TCTAGTATTAAGGGGTATATAATTATGCAAGTTCATTTTATAACACGAGGCTAGACTAAA
  AGGAAAATTTTTGGGCTACAAACTAAATCCAAATACGGTCAGGGGCTGAACAGTATTCCT
  GGCTTCAAAATAGGAGGGATCTGTTTCATTATCTGGCTGGGGGATGAAAGGCATAATCTG
  ATGCTGCAAATTTTCCCAGCCCACATCCCTGAAGAAAGGAGGACGTTTTAACTTTTTCAT
  TCCAGCTCTTTTTGGATCATCAATGGGTAAAAGAATTTCTACTGCACTTTGAGCATTAAA
  AAAAAACTTTTTTTTCCCTTTGGGCCCAGGGAAATCTCTTTTCAGAAAATTCCCGAAATA
  CTTGGCGGGGGTGTTCCACCTTTGAAAGGGGGAATTCCTGTTGAAAAATTAAAACAGCAA
  ACTCCCAGGGCCCCCCTATTACCCGAAGGACCATGGGCCCCTGGCCTAAAAACACCTCAG
  GGGCAAGGTACCTCGGGGTCTCTATAAATACCCCCAACCTTAAAGGGGGGCCCCCCCCTT
  TATATACACTCTTTGGAGATTCGGGATTGGATTAACCCACCTGTTTCTTACTTGGGCTTT
  GAGGGGCCCCAACAGACTCTCTTTTTCGGAGAGGGGTTAACCCCCGGGGAATGACACCGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_032844
• ORF Size: 2637 bp
• Insert Size: 3160
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_032844.1, NP_116233.1
• RefSeq Size: 3084
• RefSeq ORF: 2637
• Locus ID: 84930
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: This gene encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Feb 2010]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.