SSH2 (NM_033389) Human Untagged Clone

CAT#: SC104464

SSH2 (untagged)-Human slingshot homolog 2 (Drosophila) (SSH2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SSH2
• Synonyms: SSH-2; SSH-2L
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC104464 sequence for NM_033389 edited (data generated by NextGen Sequencing)
  ATGGCTTTGGTCACGGTCCAGCGGTCACCTACCCCCAGCACCACCTCCAGCCCCTGCGCC
  TCNGAGGCAGACAGTGGGGAGGAAGAATGCCGGTCACAGCCCAGGAGCATCAGCGAGAGC
  TTTCTAACTGTCAAAGGTGCTGCCCTTTTTCTACCACGGGGAAATGGCTCATCCACACCA
  AGAATCAGCCACAGACGGAACAAGCATGCAGGCGATCTCCAACAGCATCTCCAAGCAATG
  TTCATTTTACTCCGCCCAGAAGACAACATCAGGCTGGCTGTAAGACTGGAAAGTACTTAC
  CAGAATCGAACACGCTATATGGTAGTGGTTTCAACTAATGGTAGACAAGACACTGAAGAA
  AGCATCGTCCTAGGAATGGATTTCTCCTCTAATGACAGTAGCACTTGTACCATGGGCTTA
  GTTTTGCCTCTCTGGAGCGACACGCTAATTCATTTGGATGGTGATGGTGGGTTCAGTGTA
  TCGACGGATAACAGAGTTCACATATTCAAACCTGTATCTGTGCAGGCAATGTGGTCTGCA
  CTACAGAGCTTACACAAGGCTTGTGAAGTCGCCAGAGCGCATAACTACTACCCAGGCAGC
  CTATTTCTCACTTGGGTGAGTTATTATGAGAGCCATATCAACTCAGATCAATCCTCAGTC
  AATGAATGGAATGCAATGCAAGATGTACAGTCCCACCGGCCCGACTCTCCAGCTCTCTTC
  ACCGACATACCTACTGAACGTGAACGAACAGAAAGGCTAATTAAAACCAAATTAAGGGAG
  ATCATGATGCAGAAGGATTTGGAGAATATTACATCCAAAGAGATAAGAACAGAGTTGGAA
  ATGCAAATGGTGTGCAACTTGCGGGAATTCAAGGAATTTATAGACAATGAAATGATAGTG
  ATCCTTGGTCAAATGGATAGCCCTACACAGATATTTGAGCATGTGTTCCTGGGCTCAGAA
  TGGAATGCCTCCAACTTAGAGGACTTACAGAACCGAGGGGTACGGTATATCTTGAATGTC
  ACTCGAGAGATAGATAACTTCTTCCCAGGAGTCTTTGAGTATCATAACATTCGGGTATAT
  GATGAAGAGGCAACGGATCTCCTGGCGTACTGGAATGACACTTACAAATTCATCTCTAAA
  GCAAAGAAACATGGATCTAAATGCCTTGTGCACTGCAAAATGGGGGTGAGTCGCTCAGCC
  TCCACCGTGATTGCCTATGCAATGAAGGAATATGGCTGGAATCTGGACCGAGCCTATGAC
  TATGTGAAAGAAAGACGAACGGTAACCAAGCCCAACCCAAGCTTCATGAGACAACTGGAA
  GAGTATCAGGGGATCTTGCTGGCAAGCAAACAGCGGCATAACAAACTATGGAGATCTCAT
  TCAGATAGTGACCTCTCAGACCACCACGAACCCATCTGCAAACCTGGGCTAGAACTCAAC
  AAGAAGGATATCACCACCTCAGCAGACCAGATTGCTGAGGTGAAGACCATGGAGAGTCAC
  CCACCCATACCTCCTGTCTTTGTGGAACATATGGTCCCACAAGATGCAAATCAGAAAGGC
  CTGTGTACCAAAGAAAGAATGATCTGCTTGGAGTTTACTTCTAGGGAATTTCATGCTGGA
  CAGATTGAGGATGAATTAAACTTAAATGACATCAATGGATGCTCATCAGGGTGTTGTCTG
  AATGAATCAAAATTTCCTCTTGACAATTGCCATGCATCCAAAGCCTTAATTCAGCCTGGA
  CATGTCCCAGAAATGGCCAACAAGTTTCCAGACTTAACAGTGGAAGATTTGGAGACAGAT
  GCACTGAAAGCAGACATGAATGTCCACCTACTGCCTATGGAAGAATTGACATCTCCACTG
  AAAGACCCCCCCATGTCCCCTGATCCTGAGTCACCAAGCCCCCAACCCAGTTGCCAGACT
  GAAATCTCAGATTTCAGTACAGATCGCATTGACTTTTTTAGTGCCCTAGAGAAGTTTGTG
  GAGCTCTCCCAAGAAACCCGGTCACGATCTTTTTCCCATTCAAGGATGGAGGAACTGGGT
  GGAGGAAGGAATGAGAGCTGTCGACTGTCAGTGGTAGAAGTAGCCCCTTCCAAAGTGACA
  GCTGATGACCAGAGAAGCAGCTCTTTGAGTAATACTCCCCATGCATCAGAAGAATCTTCA
  ATGGATGAGGAACAGTCAAAGGCAATTTCAGAACTGGTCAGCCCAGACATCTTCATGCAG
  TCTCACTCGGAAAATGCAATTTCAGTCAAAGAAATTGTCACTGAAATTGAGTCCATCAGT
  CAAGGAGTTGGGCAGATTCAACTGAAAGGAGACATCTTACCCAACCCATGCCATACACCA
  AAGAAGAACAGCATCCATGAGCTGCTCCTTGAGAGGGCCCAGACTCCAGAGAACAAACCT
  GGACATATGGAGCAAGATGAGGACTCCTGCACAGCCCAGCCTGAACTAGCCAAAGACTCA
  GGGATGTGCAACCCAGAAGGCTGCCTAACCACACACTCATCTATAGCAGACTTGGAAGAA
  GGGGAACCAGCTGAGGGGGAACAAGAGCTCCAGGGCTCAGGGATGCACCCAGGTGCCAAG
  TGGTACCCTGGGTCTGTGAGGCGAGCCACCTTGGAGTTCGAAGAGCGCTTACGGCAGGAG
  CAAGAGCATCATGGTGCTGCCCCAACATGTACCTCATTGTCCACTCGTAAGAATTCAAAG
  AATGATTCTTCTGTGGCAGACCTAGCACCAAAAGGGAAAAGTGATGAAGCCCCCCCAGAA
  CATTCATTTGTCCTCAAGGAACCAGAAATGAGCAAAGGCAAAGGGAAATACAGTGGGTCT
  GAGGCTGGCTCACTGTCCCATTCTGAGCAGAATGCCACTGTTCCAGCTCCCAGGGTGCTG
  GAGTTTGACCACTTGCCAGATCCTCAGGAGGGCCCAGGGTCAGATACTGGAACACAGCAG
  GAAGGAGTCCTGAAGGATCTGAGGACTGTGATTCCATACCAGGAGTCTGAAACACAAGCA
  GTCCCTCTTCCCCTTCCCAAGAGGGTAGAAATCATTGAATATACCCACATAGTTACATCA
  CCCAATCACACTGGGCCAGGGAGTGAAATAGCCACCAGTGAGAAGAGCGGAGAGCAAGGG
  CTGAGGAAAGTGAACATGGAAAAATCTGTCACTGTGCTCTGCACACTGGATGAAAATCTA
  AACAGGACTCTGGACCCCAACCAGGTTTCTCTGCACCCCCAAGTGCTACCTCTGCCTCAT
  TCTTCCTCCCCTGAGCACAACAGACCCACTGACCATCCAACCTCCATCCTGAGTAGCCCT
  GAAGACAGAGGCAGCAGCCTGTCCACAGCCCTGGAGACAGCAGCACCTTTTGTCAGTCAT
  ACAACCCATTTACTGTCTGCCAGTTTGGATTACCTGCATCCCCAGACTATGGTTCACCTG
  GAGGGCTTCACAGAGCAGAGCAGCACTACAGATGAGCCCTCTGCAGAACAGGTTAGCTGG
  GAAGAAAGTCAGGAGAGCCCTCTCTCCAGTGGCAGTGAGGTGCCATATAAGGACTCCCAG
  CTAAGTAGCGCAGACCTAAGTTTAATTAGCAAACTTGGTGACAACACTGGGGAGTTACAG
  GAGAAAATGGACCCATTGCCTGTAGCCTGTCGACTCCCACATAGCTCTAGTAGTGAAAAC
  ATAAAGAGTCTCAGCCACAGCCCCGGTGTGGTGAAGGAGCGTGCTAAAGAAATCGAGTCT
  CGAGTGGTTTTCCAGGCAGGGCTCACCAAACCATCCCAAATGAGGCGCTCAGCTTCTCTC
  GCCAAATTAGGTTACTTGGACCTCTGTAAAGACTGCTTACCAGAGAGGGAGCCTGCCTCC
  TGTGAATCCCCTCATCTCAAACTGCTTCAGCCTTTCCTCAGAACAGACTCAGGCATGCAC
  GCGATGGAGGACCAAGAGTCCCTAGAAAACCCAGGTGCCCCCCACAACCCAGAGCCCACC
  AAGTCTTTTGTAGAACAACTCACAACAACAGAGTGTATTGTGCAGAGCAAGCCAGTGGAG
  AGGCCCCTTGTGCAGTATGCCAAAGAATTTGGTTCTAGTCAGCAGTATTTGCTCCCCAGG
  GCAGGACTTGAATTGACTAGTTCTGAAGGAGGCCTTCCCGTGCTACAGACCCAGGGACTG
  CAGTGTGCATGCCCAGCTCCAGGGCTGGCCGTGGCACCCCGTCAGCAACACGGCAGAACT
  CACCCCCTTAGGAGACTGAAAAAGGCAAATGACAAAAAACGGACAACCAACCCCTTCTAT
  AATACCATGTGA
  
  Clone variation with respect to NM_033389.2
  63 g=>n;273 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_033389 unedited
  GCACGAGGCCACCCCGCACCCCTTTCCCCATCCCGGCTCCGTCACCCTCCCGTCCCCCAC
  ACTCAGGACAAGAATGCCCTGCCCGGAACAACCCAGCAGCGCCTAGATGGCTTTGGTCAC
  GGTCCAGCGGTCACCTACCCCCAGCACCACCTCCAGCCCCTGCGCCTCGAGCTCTCATTT
  GGAAGACAGTGAATCAGCAGCATTACTTTGCTGTGAATGTGAAGAATCAGAAATCTTTAC
  TGATTCCAATGAGGCAGACAGTGGGGAGGAAGAATGCCGGTCACAGCCCAGGAGCATCAG
  CGAGAGCTTTCTAACTGTCAAAGGTGCTGCCCTTTTTCTACCACGGGGAAATGGCTCATC
  CACACCAAGAATCAGCCACAGACGGAACAAGCATGCAGGCGATCTCCAACAGCATCTCCA
  AGCAATGTTCATTTTACTCCGCCCAGAAGACAACATCAGGCTGGCTGTAAGACTGGAAAG
  TACTTACCAGAATCGAACACGCTATATGGTAGTGGTTTCAACTAATGGTAGACAAGACAC
  TGAAGAAAGCATCGTCCTAGGAATGGATTTCTCCTCTAATGACAGTAGCACTTGTACCAT
  GGGCTTAGTTNTGCCTCTCTGGAGCGACACGCTAATTCATTTGGATGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_033389 unedited
  CCTATTATGNACCCGGCCGCATTCTANGATCGATTTTTTTTTTTTTTTTTTGCCATCCAG
  ATCAATCTCTCTTTCCCCTTACTATACACACACATACACACTGGAAAAACACCCAAACCC
  TGCATGCACCAGAAACAGTAAAATGACCAAAATATTATAAAATTAACCAATAAAGTGCAT
  GTTCCTTACATATTACACCTGCCCCTTTTACAAACATTTCTTCTAGAAAGTCACATGTGT
  AGGCTCAGAATCACATGGTATTATAGAAAGGGTTGGTTGTCCGTTTTTTGTCATTTGCCT
  TTTTCAGTCTCCTAAAGGGGTGAGTTCTGCCGTGTTGCTGACGGGGTGCCACGGCCAGCC
  CTGGAGCTGGGCATGCACACTGCAGTCCCTGGGTCTGTAGCACGGGAAGGCCTCCTTCAG
  AACTAGTCAATTCAAGTCCTGCCCTGGGGAGCAAATACTGCTGACTAGAACCAAATTCTT
  TGGCATACTGCACAAAGGGCCTCTCCACTGGCTTGCTCTGCACAATACACTCTGTTGTTG
  TGAGTTGTTCTACAAAAGACTTGGTGGGCTCTGGGTTGTGGGGGGCACCTGGGTTTTCTA
  AGGACTCTTGGTCCTCCATCGCGTGCATGCCTGAATCTGTTCTGAAGAAAAGCTGAAGCA
  CTTTGAGATGAGGGGATTCACAAGAAGCAAGCCTCCTCTCTGGTAAACAGTCTTTTACAG
  AAGGCAAGTAACCTATTTGGCGAGAGAAACTGAACCCCTCATTTGGGAATGGTTGTGGAA
  CCCCGCCCTGAAACCCACCTCAGAATTCATTTCTTTACACGCTCCTTCACCACACCGGGG
  GCGGGGTGGAAACCCTTTATGTTTTCCTCTTAAAGCCATTTGGGAGTCGAAAGGCTCCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_033389
• ORF Size: 4272 bp
• Insert Size: 4700
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_033389.2, NP_203747.2
• RefSeq Size: 9166
• RefSeq ORF: 4272
• Locus ID: 85464
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Regulation of actin cytoskeleton
• Gene Summary: This gene encodes a protein tyrosine phosphatase that plays a key role in the regulation of actin filaments. The encoded protein dephosphorylates and activates cofilin, which promotes actin filament depolymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.