AKR1D1 (AK058142) Human Untagged Clone

CAT#: SC104633

(untagged)-Human cDNA FLJ25413 fis, clone TST03402, highly similar to 3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AKR1D1
• Synonyms: 3o5bred|CBAS2|SRD5B1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AK058142, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCTTTAAGCCAGGAGATGAAATATACCCTAGAGATGAGAATGGCAAATGGTTATATCACAAGTCAA
  ATCTGTGTGCCACTTGGGAGGCGATGGAAGCTTGCAAAGACGCTGGCTTGGTGAAATCCCTGGGAGTGTC
  CAATTTTAACCGCAGGCAGCTGGAGCTCATCCTGAACAAGCCAGGACTCAAACACAAGCCAGTCAGCAAC
  CAGGTTGAGTGCCATCCGTATTTCACCCAGCCAAAACTCTTGAAATTTTGCCAACAACATGACATTGTCA
  TTACTGCATATAGCCCTTTGGGGACCAGTAGGAATCCAATCTGGAGGCAGCTCCATAAACTTGCCTTGCT
  TGATCTTCCCATACTACGAGTAACTCTCCATTCAGTGCATACTCTGCACTCAGAGAAACTGGTTACAGGT
  GACCTGCAGTGTCCTGGGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AK058142 unedited
  NGGGTCAGAATTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACCANAATCACTCC
  TACAGTCAGGTTCTCCACAATGGATCTCAGTGCTGCAAGTCACCGCATACCTCTAAGTGA
  TGGAAACAGCATTCCCATCATCGGACTTGGTACCTACTCAGAACCTAAATCGACCCCTAA
  GGGAGCCTGTGCAACATCGGTGAAGGTTGCTATTGACACAGGGTACCGACATATTGATGG
  GGCCTACATCTACCAAAATGAACACGAAGTTGGGGAGGCCATCAGGGAGAAGATAGCAGA
  AGGAAAGGTGCGGAGGGAAGATATCTTCTACTGTGGAAAGCTATGGGCTACAAATCATGT
  CCCAGAGATGGTCCGCCCAACCCTGGAGAGGACACTCAGGGTCCTCCAGCTAGATTATGT
  GGATCTTTACATCATTGAAGTACCCATGGCCTTTAAGCCAGGAGATGAAATATACCCTAG
  AGATGAGAATGGCAAATGGTTATATCACAAGTCAAATCTGTGTGCCACTTGGGAGGCGAT
  GGAAGCTTGCAAAGACGCTGGCTTGGTGAAATCCCTGGGAGTGTCCAATTTTAACCGCAG
  GCAGCTGGAGCTCATCCTGAACAAGCCAGGACTCAAACACAAGCCAGTCAGCAACCCAGG
  TTGAGTGGCCATCCGTATTTCACCCAGCCAAAACTCTTGAAATTTTGCCAACAACATGAC
  ATTGTCATTACTGCATATAGCCCTTTGGGGACCAGTANGAATCCAATCTGGGTGAATGTT
  TCTTCTCACCTTTNGTAAGGATGCACTTCTAACTCATGNNGNAAAGGTCANNTAGAAGCA
  GCTCAATGTTTTGCGTTCACATCACGAGGGGNGGGGTGTCATTCTAAAAAGCTTATCTGA
  AAGAT
  
• Restriction Sites: NotI-NotI
• ACCN: AK058142
• ORF Size: 441 bp
• Insert Size: 2560
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: AK058142.1, BAB71682.1
• RefSeq Size: 1208
• RefSeq ORF: 441
• Locus ID: 6718
• Domains: aldo_ket_red
• Protein Families: Druggable Genome
• Protein Pathways: Androgen and estrogen metabolism, C21-Steroid hormone metabolism, Metabolic pathways, Primary bile acid biosynthesis
• Gene Summary: The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010]