CHMP2A (AK092868) Human Untagged Clone

CAT#: SC104721

(untagged)-Human cDNA FLJ35549 fis, clone SPLEN2004181, weakly similar to BC-2 protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CHMP2A
• Synonyms: BC-2|BC2|CHMP2|VPS2|VPS2A
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AK092868, the custom clone sequence may differ by one or more nucleotides
  
  
  AAAACGGGTGTCCGTCCCAGCTCCGGTGAGTGGCCCCTGCTGGACCGTGGATCCCGGGCGGGCGTGCGGG
  CGGCAGCGTACGAGGCCTTCTACTCGCCCGGGTGTCCGGTGCCTCGCTTCTCCCTGGGACCCTGTCGTCA
  ACATCGAGGTCTCCAACACCACCTTGCTTTGGTGCCGGGCCCACTGACTGTCCTCGGTGTATAGTGCGAC
  CGAATCTCCATCATCCCGTCCTCAGTGTACAGGATGCCCCAGCGCCCCCAACCGTCTCCCTCAGCATTCA
  GGGTCCCCAAATCCTAATGCCTTGTCCTGAGCCTCACAGCCCCACATTCACCTGTTCTTGGTACTTAGCG
  TTTCCGCCCATCCTGTCCTCCTCTATCAGAACCCCCACAATTGCTCTGTCCTCGGTGCCCACAGTCTCCA
  AAACACCGGTGCACCGGCCCGCGTCATCCCCCGCTCTCAGTCGTATCAAGGACTCCAGGGCCTCACCCAT
  AGTTCTGGAGAGGGAAGCTGAACTTGCAAGCCATAACTTCTTTTGGGGCATGGCGATGAAGGAGGGGCTC
  GGGCCAGCACTTGGATAATTTTCAGGTCTACCTGTCCCCCTTTATGTGTCCCCGGGACAATCCCAGTGTT
  CTCAGCTGCTCCCTTTTGGCTCCTCATTCCTGCCTCCAGTCTCCGTTAGCCCCTTCCCATTTGGCAAGGC
  TCCCGTGACCCTGTTCTGCTTCTTGCCCTCCTGGGCCCCATGCCCTACAACTGGGCCTCACTCACATCTG
  TCTCAGGCCTGCCAGTGAGCTTCTACCATCATGGACCTATTGTTCGGGCGCCGGAAGACGCCAGAGGAGC
  TACTGCGGCAGAACCAGAGGGCCCTGAACCGTGCCATGCGGGAGCTGGACCGCGAGCGACAGAAACTAGA
  GACCCAGGAGAAGAAAATCATTGCAGACATTAAGAAGATGGCCAAGCAAGGCCAGATGGTGAGTGTGGGT
  GGTCGGGCAGGTTGCTGTCAATCAGGCACGGCTCTAACAGCAGTGAACAAGAGAGACCAGACACCAAACA
  CAGGTGCTTTCAGCAAAACGAGTGGAGTGAAAGGTCAGCAGGGCTTCCCTAGTTTGAGGGTCTGGAAGGC
  TGCCTCCAAGGAACTGGTATGAGATCCAAGGCTTGAGTGATGAGAGTGAGCCTACAGATCTGGGCAGGGA
  ATGTGTTAAGCAGACAGAGCAGCAAATGTTAAAAAAGAGCCTCAAAAAAATGGGAGATGACAGGTGAGCT
  TCAAGAGTTGGGCATGGACCAGACAATTCAGAACTCTGGGCCAAAGTGGGAGCTAAGTTGGAAGGTTAGG
  GATTACAGGGCCGGGCGCAGTAGCTCAGAGACCTGTAATCCCAGCACTTTGGGAGGCAGAGGTGGTTGGA
  TCACCTGAGGTCAGGACTTCGAGACCAGCCTGACCAACACAGAGTAACCCCGTCTCTACTGAAAATAAAA
  AAAACTAGCCAGGCATGGTGGCGCACGCCTGTAATCCCAGCTACTCAGCAGGGCTGAGGCAGGACAATCT
  CTTGAACCCAGGAGGCGGAGGTTACAGTGAGCCAAGATCATGCCACTGCACTCCAGCCTGGGTGACAGAG
  CGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAACCAGTTAACTATAAGGATAAGCTGGCCCGGCATGATG
  GCTCAAGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACCTGAGGTCAGGATTTCGAGA
  CCAGCCTGGCCAACATGGCAAAACCCCACTCTACCAAAAATTAGCCGGGCATGGTGGTGCATACTTGTTA
  TCCCAGCTATTCGAGAGGCTGAGGCAGAAGAATCGCTTGAGGCCGGGAGGCACAGTTTGCAGTGAGCCAA
  GATTGTGCCACTGCACTCCAGCCTAGGCAACAAAGCAAGACTCCAACTC
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AK092868 unedited
  CCCCCCCACCCCACCNNNNCCACCCCCCCCGTTCAAATTTGTATACGACTCATATAGGCG
  GCCGCGNAATTCGCGGCGGCGACAGGACCGAGGGGCCTTAGTTGGTGGGCAAGTCGGGGA
  TCCCAGAAAGAGAAGCGTGACCCGGAAGCGGAAACGGGTGTCCGTCCCAGCTCCGGCCTG
  CCAGTGAGCTTCTACCATCATGGACCTATTGTTCGGGCGCCGGAAGACGCCAGAGGAGCT
  ACTGCGGCAGAACCAGAGGGCCCTGAACCGTGCCATGCGGGAGCTGGACCGCGAGCGACA
  GAAACTAGAGACCCAGGAGAAGAAAATCATTGCAGACATTAAGAAGATGGCCAAGCAAGG
  CCAGATGGTGAGTGTGGGTGGTCGGGCAGGTTGCTGTCAATCAGGCACGGCTCTAACAGC
  AGTGAACAAGAGAGACCAGACACCAAACACAGGTGCTTTCAGCAAAACGAGTGGAGTGAA
  AGGTCAGCAGGGCTTCCCTAGTTTGAGGGTCTGGAAGGCTGCCTCCAAGGAACTGGTATG
  AGATCCAAGGCTTGAGTGATGAGAGTGAGCCTACAGATCTGGGCAGGGAATGTNGTAAGC
  AGACAGAGCAGCANATGTTAAAAAAGAGCCTCANAAAATGGGAGATGACAGGTGAGCTTC
  AAGAAGTGGGCATGGACCAGACANTNCAGAAACTCTGGCCCAAAGTGGGAGCTAAGTTGG
  AAGGTTAGGGGATACAGGGCCCGGNCGCAGTAGCTCAGAGACCTGTAATCCCAGCACTTG
  GAGGCAGAAAGGGGGGNNNAAAAACCNAAAGNAAGGAAATTTAAACCAANCTGACCCACC
  CAAAAAAACCCCCGGTTTTACGGAACAAAAAAACAACCACCCGCGCNTGGGGGCCCCCCC
  CCGTACCCCCAATTCCTCAAAAGCTTGGGGCGTGGAAATTTTTGTTACCCATAGGCGGGG
  GGTCCCCCGCCCCTAAATCTCCCATTCGCCCCCCTCTTGGGGTACAACCCCATCCTTCTC
  CAAAAAAAT
  
• Restriction Sites: NotI-NotI
• ACCN: AK092868
• ORF Size: 1939 bp
• Insert Size: 1000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: AK092868.1
• RefSeq Size: 1939
• RefSeq ORF: 1939
• Locus ID: 27243
• Protein Pathways: Endocytosis
• Gene Summary: CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]). [supplied by OMIM, Mar 2008]