SPTLC1 (BC007085) Human Untagged Clone

CAT#: SC105913

SPTLC1 (untagged)-Human serine palmitoyltransferase, long chain base subunit 1, transcript variant 2 (cDNA clone MGC:14645 IMAGE:4094854), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SPTLC1
• Synonyms: HSAN; HSAN1; HSN1; LBC1; LCB1; long chain base biosynthesis protein 1; MGC14645; OTTHUMP00000022810; OTTHUMP00000022811; serine-palmitoyl-CoA transferase 1; serine C-palmitoyltransferase; serine palmitoyl; serine palmitoyltransferase subunit 1; SPT1; SPTI
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for BC007085, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGACCGCCACGGAGCAGTGGGTTCTGGTGGAGATGGTACAGGCGCTTTACGAGGCTCCTGCTTACC
  ATCTTATTTTGGAAGGGATTCTGATCCTCTGGATAATCAGACTTCTTTTCTCTAAGACTTACAAATTACA
  AGAACGATCTGATCTTACAGTCAAGGAAAAAGAAGAACTGATTGAAGAGTGGCAACCAGAACCTCTTGTT
  CCTCCTGTCCCAAAAGACCATCCTGCTCTCAACTACAACATCGTTTCAGGCCCTCCAAGCCACAAAACTG
  TGGTGAATGGAAAAGAATGTATAAACTTCGCCTCATTTAATTTTCTTGGATTGTTGGATAACCCTAGGGT
  TAAGGCAGCAGCTTTAGCATCTCTAAAGAAGTATGGCGTGGGGACTTGTGGACCCAGAGGATTTTATGGC
  ACATTTGAATGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC007085 unedited
  GTTCCCATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGCTAACTATG
  GCGACCGCCACGGAGCAGTGGGTTCTGGTGGAGATGGTACAGGCGCTTTACGAGGCTCCT
  GCTTACCATCTTATTTTGGAAGGGATTCTGATCCTCTGGATAATCAGACTTCTTTTCTCT
  AAGACTTACAAATTACAAGAACGATCTGATCTTACAGTCAAGGAAAAAGAAGAACTGATT
  GAAGAGTGGCAACCAGAACCTCTTGTTCCTCCTGTCCCAAAAGACCATCCTGCTCTCAAC
  TACAACATCGTTTCAGGCCCTCCAAGCCACAAAACTGTGGTGAATGGAAAAGAATGTATA
  AACTTCGCCTCATTTAATTTTCTTGGATTGTTGGATAACCCTAGGGTTAAGGCAGCAGCT
  TTAGCATCTCTAAAGAAGTATGGCGTGGGGACTTGTGGACCCAGAGGATTTTATGGCACA
  TTTGATGTTCATTTGGATTTGGAAGACCGCCTGGCAAAATTTATGAAGACAGAAGAAGCC
  ATTATATACTCATATGGATTTGCCACCATAGCCAGTGCTATTCCTGCTTACTCTAAAAGA
  GGGGACATTGTTTTTGTAGATAGAGCTGCCTGCTTTGCTATTCAGAAAGGATTACAGGCA
  TCCCGTAGTGACATTAAGTTATTTAAGCATAATGACATGGCTGACCTCGAGCGACTACTA
  AAAGAACAAGAGATCGAAGATCAAAAGAATCCTCGCAGGGCTCGTGTAACTCGGCGTTTC
  ATTGTAGTAGAAGGATTGTATATGAATACTGGAACTATTTGNCTCTTCAGAATGGNNTAG
  TAATACAATACAAGCAGAATCTTCTGGGAGAAAGCTTCATTTGAGTCTAGAGAGCTGGCG
  AGAGTACTGACACTTGATCATATGAGATATGACTATCAGGCACTGAGATGCCTGCTTATT
  GAGTCT
  
• Restriction Sites: NotI-NotI
• ACCN: BC007085
• ORF Size: 432 bp
• Insert Size: 2750
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC007085.1, AAH07085.1
• RefSeq Size: 973
• RefSeq ORF: 432
• Locus ID: 10558
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism
• Gene Summary: This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013]