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BPTF (AL833375) Human Untagged Clone
CAT#: SC105977
(untagged)-Human mRNA, cDNA DKFZp667H1714 (from clone DKFZp667H1714)
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Symbol | BPTF |
| Synonyms | FAC1|FALZ|NURF301 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for AL833375, the custom clone sequence may differ by one or more nucleotides
CCCACGCGTCCGGACTGTACTCCCAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATGGTACT GTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCACAGCCAGCACCACCACCACCACTGTTT CCACGACAGCAGCAGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGA CAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCT TCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGAAG TTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAA GCCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGT CCATCACAGACTCGAATACGTCCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGA CTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCAAGGCCAGCCACA GTCACAACCCCAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACT CCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGA TAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAA GCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAG AAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTA AGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACC AGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTT CTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAA AGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTAT CTGTAAAACGCCTTATGATGAATCTAAGTTCTATATTGGCTGTGATCTTTGTACTAACTGGTATCATGGA GAATGTGTTGGCATCACAGAAAAGGAGGCTAAGAAAATGGATGTGTACATCTGTAATGATTGTAAACGGG CACAAGAGGGCAGCAGTGAGGAATTGTACTGTATCTGCAGAACACCTTATGATGAGTCACAATTTTATAT TGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTC ATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAG AGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCT TGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACC ATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTT TTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATT CTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCT TAAAGTTCAGCGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAG GAGCCAGATGTTTTTAGTCAGGCTATCCTGACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACA GTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAAAGTCAACGACACCATTATCT TGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAA AGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGT GAAGAAGCTGGTTTAGAGTCTCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTT TTTTATTGCTGCCCTCATTTGTCAGCTAAGTATTTTTTCTTATAAAATCCAGCCCCGGTTACATATAATC ATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTTCTTTCTATGA AAGGAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGT AGATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATA TAACAGTACAATTTGTCAATTACTCTGCACCAGGCTAAAGTGAGTAAAATCTATTTGAAGGTATCTTGTT TGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAACTATGGATGTATATGAAACAA AATAAATGGAGATAATTTTTCTCCCACAGACAGAGGTGTCTTTGAATGTGCGCTAATGATTATCTGTAAG CCTTTGTGGGGAGGGAGGCCTGCAAGGTCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTCTCCAG GACAGCAGTGGCCCCTCGCTTTATCATTCCCAGTCCATTGTCATCACGTCAGAGAAAAATCTTCAGGGGT GCTAATCCTGTTGCATCAGTTGATCATACTAACGAGAACGGTAATGCGACAAGATACACATTGCCTTCAT CTGTACATTCTGTGATACCAGGCAAATTACCAATTACACACAGCTACTTATATTTTATGAAGGGCATTTT TTAGATGACCTCATCCTCTGTGTTATTTGTTGATTGGGTTTGTTTTCTGTTTGTTGGTTTGTTTGTTTCT TCCACGTAAGGAAAAGTAGTGTAAACAGTAGCGAGAAAATGGAAACCACAGAGGAAGATGTATTTTGCAT GTTTTTCCTTTCAGTGTTCTTACACGTTGTATCACTGCATTGTGGTAATAGCTTCTATAAAATCTGCCAT AGTTGGATTATGCAGCTTTGCAAAAATTTTTACTAGATTTTGCACTAACTCATATTAGCTTTGTCCTACC AACTTCTGGAATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCCTTTTAATGTTTCCCTGCTATGCAAA ACCTTTCCCAGACCTCAGTTTCTTAAAAGAAAGATGTTGCTACAGTTCCCGATTCTTTCTTATTACAGGC TCAGGTGTACAGGTTATTCTGGGTTAATTTTATCTAATGAAGCCCATTCCTTTTTGTACATAAAGATGTC ACTTAAACTTATGCTTACAAACTAAAGACTAATCGCTCAATATGAAAACATGAAAAAATTTTTGCTTAAA GTATTAAGATGGAAGTAGTTAAATATGGGTTATTTTGTCCTTTTACTTTTTTAAAAAATGTTACATATTG TATGCACTGTGCTGATGCAAGAATTCTACATTTTAATGAATTATAAAATTATTCTGCATCTCATCACATC ACAGTATTTCTGTACTATTTATTCATATATATAAATATATATGGGCTTAATCATTTAAAATTTGTTGCAG CAAGAACTTTCCTACCTGTAGGCAATAGATTGCTATGTTTTTAACAAATTGTGGCAAATTCTAAACAGCA ATTCTTTTGTACGTAATAGGACATTTCATCCTAGAAAAATAAAGTAATGTTTTTGACATTGCAAAAGAAA AAAAAAAAAAAAAA >OriGene 5' read for AL833375 unedited
NGGGGTGGTTCAGAATTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGGG AAAGGCAATTATTCGAACACCTGTGATGGTACAGCCAGGTGCTCCTCAGCAAGTGATGAC TCAAATCATCAGGGGGCAGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCTC AACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATATACAGTCTTCAGC CTCACAACCCCCTCGCCCTCAACAAGGACAAGTGAAGCTCACCATGGCTCAACTTACTCA GTTAACACAGGGCCACGGTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTCA AACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCCCAGGCCCAGGCCA GCAGCTAATGCAAGCTGCAATGCCAAATGGTACTGTTCAGCGATTCCTCTTTACCCCATT GGCAACAACAGCCACCACAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAGG TACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAAC CCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCA GCCTTCAAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTC AGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCAC AACCCACCCACGCACAGTCATCCAAAGCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTA ATGTCCAAGGACAGNTCTCTGTTCGTGTCCCAAGTCCATCACAGACTCGAATACGTCCAT CAACTNCTN >OriGene 3' read for AL833375 unedited
GTACAGCTATGNNACCGCGGCCGCAATCTAGNGATCGGTTTTTTTTTTTTTTTTTTAATA AACAAAGTTTTCTCGCTTCTGCCACAATAGTAAAACCATCTGATCTTGACAAGATAATGG TGTCGTTGACTTTGCTTTTTTCTTGTCCGTTGGACAAAATTGGCCAAGAATATAATTGGA CTGTTATGACCAATAAAAACGAAGTTTAGGTCAAGTCTTGTCAGGATAGCCTGACTAAAA ACATCTGGCTCCTTAATTTAAAATAGTTCAGACAACCAGATTCTTGCTGTGTTTTATGTT AGGTTAACACGCTGAACTTTAAGAAGCTGTAGACTGCAGTTTGTTGTTATGAGACCTGCT AGCTTTGAAGCCTTTCAATTTCTGTACAAAGAATGATTCGAGAACTTCTGCACACTGGTA AAATGGGGAGTCACTTGGATTGTAGTAACGACAGTTATCAAAAATTTTGGTCATATCTGC CACAAATTCCGTCAGCTTTTCATAATATCGTCTTTGTACTCTTTCTTCCATGGTGGCAAG GTCCATAGGTTCCTTAATAACACCATAATAATCTGGTGCATCATTAGGGTCTACTGGTTC AAGGAAAGGCCAGGCCATCTTATGGGCCTGTAAGGAACGGAGCACCCTCTTCAACCCCTC ATAATCCTTCTCTGTTAGTGGCGTGAGCACTGTCATGGCATCCTCTGTTGACTGGCACTG TGGACAGACATACTCATCAATGAGCTCTGCCTCACTTTGCAAGATGCCAACGCAGCGCCC ATGGTACCAATTCTGACACCGATCACAGCCAATATAAAATTGTGACTCATCATAAGGGTG TTCTGCAGATACAGTACAATTCCTCACTGCTGCCCTCTTGTGCCCGTTTACATCATACAG ATGTACACATCCATTTTCTTAGCCTNCTTTTCTGTGATGCCA |
| Restriction Sites | NotI-NotI |
| ACCN | AL833375 |
| Insert Size | 2850 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | AL833375.1 |
| RefSeq Size | 4074 bp |
| RefSeq ORF | 4074 bp |
| Locus ID | 2186 |
| Cytogenetics | 17q24.2 |
| Domains | BROMO, PHD |
| Protein Families | Druggable Genome |
| Gene Summary | 'This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif, suggested it might play a role in the regulation of transcription. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. The protein encoded by this gene is actually much larger than originally thought, and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation. The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex. In Drosophila, the NURF complex, which catalyzes nucleosome sliding on DNA and interacts with sequence-specific transcription factors, is necessary for the chromatin remodeling required for transcription. Two alternative transcripts encoding different isoforms have been described completely. [provided by RefSeq, Jul 2008]' |
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