IBRDC2 (RNF144B) (AJ420555) Human Untagged Clone

CAT#: SC106248

(untagged)-Human mRNA full length insert cDNA clone EUROIMAGE 186647

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RNF144B
• Synonyms: IBRDC2|PIR2|bA528A10.3|p53RFP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AJ420555, the custom clone sequence may differ by one or more nucleotides
  
  
  GGCACGAGGCGGCACGAGGTCTGTCAGTAAACTCTTTAAGCTTGGTGCCGCAAAGAGTCTTTAAATGGGG
  GCTGATTTCAAGTAACCTAAAAGACTGTGTTATCAGAGGAAGAGGTCCCAAATTTGGAGTAAAGATGGGA
  GAAAATAAATATGTGCTATTTCCTTGGCGAGTTGGGGGAATTTGCCACCTTACAGAGTTTGTATCACTGA
  ATTAGCTGCTTTTGTTTTTTTTTTTTTTTTTTTTTTGCCAGGGCTATGGAGTGGGGGTTGTTTGTCAAAC
  TGATTTTCAATAATTGGATTTAATTTTTTTTAACATTGAAAAGTGCCTGAAAAATGGTAAATTCTTAAAT
  GTGTGTGAGATTGTCAGAATCAACAAAACTAGGTTGGTTAAACATATCTCTGGTACATCAAGGGGCATGA
  TACAAACCAGTCTAAAGACTGTTTATAAAGGAGAGAGCTGGCGACTTATTTTTATTTTTTTTTTTTGGAC
  AGAGTCTCCCTTTGTCACCCAGGCCGGAGTGCAGTGGCATGATCATGGTTCACTTCAACCCCTACCTCCT
  GGGCTCAAGTGTTCCTCTCACCTTATCCTCCTGAGCAGCTGGGACTACAGGCACACACCACCACACCTGG
  CTAAGTTTTGTATTTTTTGTAGAGATGGGGTTTCTCTGTGTTGCCCAGTCTTGTCTCAAACTCCTGGGCT
  CAAGCGATCCACCCACCTTGGGCTCCCAAAGTGTTGGGATTACAGGTGTGTGTCACTGTGCCTGACAGCT
  GACAGTTTTAACTGACAACTTTGATAACAGAGGCTGCTATTTTTGTTTTAGATAATTGGCCAGTGACAGA
  GTTTACCCTTGCCTCCTTTCTTGGTCTGCCAGCTTTGTCCTTTCTGAGTGATTCTCTTTCTGTATTGAGA
  GGAAGTGTGGGTCTACATAGGGATGTTTGGATGCTATGGCAAGAATCTTTTTGTGTTTGGAGTGTAGTCC
  ATTTGCAATAGAAATAAAAAAATCCGTCACCAAATTGTAACCTGGATGTTATAGCCCAGCATCTAGAAAT
  CCTATGAAATGTATTAGCACAATATCTTGCCATTGTCCCATCTAGGAAATTTTTTCTTGTTGTGAGGTAG
  GGAAGTGAGGAGGAAAGCCATGCCGAAGCAAATGTTAGAATCTTAGGCATCCTATTTGTTCATGCCATGG
  GTATTTGCTTTGGACTTGGAGTCTGTACTTTGAAAGAGGCCTTTGAAAAACAAATAATTCTGTGTGAATT
  TTCTTGTAGCGTGCTTCATGAAAATATCTACTTATCCAGGTTTGCAAATGTACATGTTCATTTGAATGTA
  AATCACCATTTCTTGGAACCCCACGTTTTTTCTTAAAAATTATTCTGAATTAAATGTATATTTCTTTAGC
  CTTCCCTACACAGTACTAATAAAAGACTTTTCTTTCTGTTCATGAAAAAAAAAAAAAAAAAAAAAAAGG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AJ420555 unedited
  NAACATGTCAGAATTGTATACAACTCATATAGGCGGCCGCGNAATTCGCACCAGAGAGAA
  CAGTCTCGAGTTTTTTTTTTTTTTTTTTTTTGCCAGGGCTATGGAGTGGGGGTTGTTTGT
  CAAACTGATTTTCAATAATTGGATTTAATTTTTTTTAACATTGAAAAGTGCCTGAAAAAT
  GGTAAATTCTTAAATGTGTGTGAGATTGTCAGAATCAACAAAACTAGGTTGGTTAAACAT
  ATCTCTGGTACATCAAGGGGCATGATACAAACCAGTCTAAAGACTGTTTATAAAGGAGAG
  AGCTGGCGACTTATTTTTATTTTTTTTTTTTTTGGACAGAGTCTCCCTTTGTCACCCAAG
  CCGGAGTGCAGTGGCATGATCATGGTTCACTTCAACCCCTACCTCCTGGGCTCAAGTGTT
  CCTCTCACCTTATCCTCCTGAGCAGCTGGGACTACAGGCACACACCACCACACCTGGCTA
  AGTTTTGTATTTTTTGTAGAGATGGGGTTTCTCTGTGTTGCCCAGTCTTGTCTCAAACTC
  CTGGGCTCAAGCGATCTACCCACCTTGGGCTCCCAAAGTGTTGGGATTACAGGTGTGTGT
  CACTGTGCCTGACAGCTGACAGTTTTAACTGACAACTTTGATAACAGAGGCTGCTATTTT
  TGTTTTAGATAATTGGCCAGTGACAGAGTTTACCCTTGCCTCCTTTCTTGGTCTGCCAGC
  TTTGTCCTTTCTGAGTGATTCTCTTTCTGTATTGAGAGGAAGTGTGGGTCTACATAGGGA
  TGTTTTGATGCTATGGCAAGAATCCTTTTGTGTTTGGAGTGTAGTCCATTTGGCATAGAA
  TAAAAAAATCCGTCCCCAATTGTACCTGGGATGTTATAGCCCAGCATCTTGAAATCCTAT
  GAAATGTTTTAGCACATATCTTGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for AJ420555 unedited
  GGCAAACCATGGTCGTCGCCGCACCCTANGATTCGGTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTCAAAAACAAAAAAAAAATTCTTTTATTATTCCTG
  GGGAGGGAAGGCTAAAAAAATATCCCTTTAATTCAAAATATTTTTTAAAAAAAAACGGGG
  GGTCCCAAAAAAGGGGGATTTACTTTCAAATGAACATGTCCTTTTGCAAACCGGGATAAT
  TAAATTTTTTCATGAACCCCCCTCCAAAAAAATTCACCCAAAATTTTTTGTTTTTAAAAG
  GCCTTTTTCAAAGTACAAACCCCAAGTCCAAAGCAAATCCCCTTGGCATGAACAAATAGG
  ATGCCTAAAATTCTAACATTTGCTTCGGCATGGTTTTCCTCCTAATTTCCCTACCTCAAA
  AAAAGAAAAATTTTCCTAAATGGGACAATGGCAAAATATTGGGCTAATACATTTCATAGG
  ATTTCTAAATGCTGGGCTATAACATCCAGGTTACAATTTGGGGACGGATTTTTTTATTTC
  TTTTGCAAATGGACTACCCTCCAAACCCAAAAAGATTCTTGCCATAGCATCCAAACATCC
  CTATGTAAACCCACACTTCCTCTCATTACAAAAAGAGAACTCCTCAAAAAGGACAAAGCT
  GGCAAACCAAAAAAGGAGGCAAGGGTAAACTCTGTCACTGGCCAATTATCTAAAACAAAA
  ATAGCAGCCTCTGTTATCAAAGTTGTCAGTTAAAACTGTCAGCTGTCAGGCACAGTGACA
  CACACCTGTAATCCCAACACTTTGGGACCCCAAGGTGGGTAAATCGCTTGAGCCCAGATT
  TTGAGACAAGACTGGGCAACACAGAAAAACCCCTCTTTCAAAAATACAAACC
  
• Restriction Sites: NotI-NotI
• ACCN: AJ420555
• ORF Size: 1469 bp
• Insert Size: 1350
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: AJ420555.1
• RefSeq Size: 1469
• RefSeq ORF: 1469
• Locus ID: 255488
• Protein Families: Transmembrane
• Gene Summary: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se. [UniProtKB/Swiss-Prot Function]