Signal Peptide Peptidase (HM13) (NM_178582) Human Untagged Clone

CAT#: SC107174

HM13 (untagged)-Human histocompatibility (minor) 13 (HM13), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HM13
• Synonyms: H13; IMP1; IMPAS; IMPAS-1; MSTP086; PSENL3; PSL3; SPP; SPPL1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC107174 sequence for NM_178582 edited (data generated by NextGen Sequencing)
  ATGGACTCGGCCCTCAGCGATCCGCATAACGGCAGTGCCGAGGCAGGCGGCCCCACCAAC
  AGCACTACGCGGCCGCCTTCCACGCCCGAGGGCATCGCGCTGGCCTACGGCAGCCTCCTG
  CTCATGGCGCTGCTGCCCATCTTCTTCGGCGCCCTGCGCTCCGTACGCTGCGCCCGCGGC
  AAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCCCATC
  ATCGCCAGCTGCACACTCTTGGGGCTCTACCTCTTTTTCAAAATATTCTCCCAGGAGTAC
  ATCAACCTCCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCTGGCCCTGTCCCACACC
  ATCAGGTCAGAAGGCATCTCTCTGCAACATTTGAAGCAGCTTTCTCGGGAACCAGTACAG
  GGTCTTGGATGA
  
  Clone variation with respect to NM_178582.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_178582 unedited
  GTATACGACTCACTATAGGGCGGCNCGCGAATTCGCACGAGGGGGGAACGTGGCTTTCCC
  TGCAGAGCCGGTGTCTCCGCCTGCGTCCCTGCTGCAGCAACCGGAGCTGGAGTCGGATCC
  CGAACGCACCCTCTCCATGGACTCGGCCCTCAGCGATCCGCATAACGGCAGTGCCGAGGC
  AGGCGGCCCCACCAACAGCACTACGCGGCCGCCTTCCACGCCCGAGGGCATCGCGCTGGC
  CTACGGCAGCCTCCTGCTCATGGCGCTGCTGCCCATCTTCTTCGGCGCCCTGCGCTCCGT
  ACGCTGCGCCCGCGGCAAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGC
  CGCCCGCTTCCCCATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTCTTTTTCAAAAT
  ATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCT
  GGCCCTGTCCCACACCATCAGGTCAGAAGGCATCTCTCTGCAACATTTGAAGCAGCTTTC
  TCGGGAACCAGTACAGGGTCTTGGATGAGAACATGACTTTTGGCATCATTCAGAGCCAGG
  TTTGAATCCTGGCTATAAAACTCAAGGGACTCTTTCCCCTGCACACTGTAGATGACTAGG
  ACAAGAACAATGACCTCTCTGGGCCACAGTTTCCTTATAGACTGANGANGATCTGGTNGG
  GGTGTTTCCACCACCACAGCTGNTGNGAAAGTGATTTGTGAGCAGTATGTCATGTTNNAG
  TGTGACAGTACTCAGGTGGAGTACACCAGTACACTGCCCCGGGGGGTGTGCCCTAACTGT
  GTGCTAGTGGCCATGGTGGGCTCTACACATGGAATCGTGTTTCGTAAGGAGCANAGGCAC
  TATTGAAAGTTTNGGACG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_178582 unedited
  CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCACTCT
  GTCGCCAGGCTGGAATGCAGTGGTGCAATCTCGGCTCACTGCAACCTCCGCCTCCCAGGT
  TCAATGATTCTCCTACCTCAGCCTCCTGAGTAGCTGGGACTACAGGCATGCACCACCATG
  CCCAGCTAATTTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGATGG
  TCTCAAGCTCCTGACCTTGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAG
  GCATGAGCCACCACCTGGCCTCATATTGGCTTTCAATGCTTTTGGGAGCAGATTCTGCCC
  ATGCCCTCAATGTGCACAAACTTTCTAGCACCTGACCTCTCCCTCCTTTGTACGTCTTCC
  AGGTTTCCTACCCTTCAAAGAAAGCTAAGTTCAAGGTGAGTTCCTTCCTTCTGGGAACCC
  TGGCCACCTCTTGGTCTATCAGGGTTTCTCAGCCTGAGGCTGCACCTCTTCAACGGGGCA
  GAAAGAAACATACTGGGACATCTCTGTAGTCACCAAGCTGGGGAATACTGGTATGCCACT
  TCCATTTGGTGAGCAAGGCAAGGGTTGCCAACTGTTTGCAATACATGCGATACCCCTGCA
  GAATGGAGAACTGGCCTGTCCAAAAAAAAGTAGCACCCCCCTCTATGACCACTTTCCCCA
  ATGATAGACCCGAGCATGGGGACAGTTGAATTATGTAACACAGGGAAATAGATGGCGCTT
  GAAGCAACCCTGGGTTGAACCCTGCCCTGCGCCTATAATGGGGGAACCCACAAAATTTTT
  AACCCTTGGGGTTCAGTTTCACGGCCATCAACAGCGGGAAGCCAAACCCCCTTTAGGGTG
  GTTGCNCGGTACCCACAATAGGACGTCACCTAAATCCCCTGACACCTTTAACCCATATAC
  GGGTTAAAGCTCTCCACGACCCCCGGAAGGGGCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_178582
• ORF Size: 432 bp
• Insert Size: 1880
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_178582.1, NP_848697.1
• RefSeq Size: 2011
• RefSeq ORF: 432
• Locus ID: 81502
• Protein Families: Protease, Transmembrane
• Gene Summary: The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (4) contains an alternate segment compared to variant 1, that causes a frameshift. The resulting isoform (4) is shorter and has a distinct C-terminus compared to isoform 1.