PIP5KI gamma (PIP5K1C) (NM_012398) Human Untagged Clone

CAT#: SC107219

PIP5K1C (untagged)-Human phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (PIP5K1C), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PIP5K1C
• Synonyms: LCCS3; PIP5K-GAMMA; PIP5K1-gamma; PIP5Kgamma
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_012398 edited
  GCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCATTTAGGTGACACTATAG
  AATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGGCACGAGGCAGCTCGGGTC
  CCCCTCGGGCGCCCCCGCCGCCGTCCGCGCGCGGCCATGGAGCTGGAGGTACCGGACGAG
  GCGGAGAGCGCTGAGGCGGGGGCCGTGCCCTCGGAGGCGGCGTGGGCGGCAGAGAGCGGG
  GCGGCGGCAGGTTTGGCTCAGAAGAAGGCGGCCCCAACAGAGGTTCTGTCCATGACGGCA
  CAGCCGGGCCCTGGCCATGGGAAGAAGTTGGGCCATCGAGGTGTGGACGCATCCGGCGAA
  ACCACCTACAAGAAGACCACCTCCTCCACCCTGAAGGGTGCCATCCAGCTGGGCATCGGC
  TACACCGTGGGCCACCTGAGCTCCAAGCCCGAACGCGACGTGCTCATGCAGGACTTCTAC
  GTGGTGGAGAGCATCTTCTTCCCCAGCGAAGGCAGCAACCTCACCCCCGCCCACCACTTC
  CAGGACTTCCGCTTCAAGACCTATGCACCTGTCGCCTTCCGCTACTTCCGGGAGCTCTTT
  GGGATCCGGCCAGATGATTACTTGTACTCCCTGTGCAATGAGCCGCTGATCGAGCTGTCC
  AACCCGGGCGCCAGTGGCTCCCTCTTCTACGTCACCAGCGACGACGAGTTCATCATCAAG
  ACCGTCATGCACAAGGAGGCCGAGTTCCTGCAGAAGCTGCTCCCTGGCTACTACATGAAC
  CTCAACCAGAACCCGCGGACGCTGCTGCCCAAGTTCTATGGGCTGTACTGCGTGCAGTCA
  GGGGGCAAGAACATCCGCGTCGTGGTCATGAACAACATCCTGCCCCGCGTGGTCAAGATG
  CACCTCAAGTTCGACCTCAAGGGCTCCACCTACAAGCGGCGCGCCAGCAAGAAGGAGAAG
  GAGAAGAGCTTCCCCACCTACAAGGACCTGGACTTCATGCAGGACATGCCCGAGGGGCTC
  CTGCTGGACGCCGACACCTTCAGCGCCCTGGTCAAGACGCTGCAGCGGGACTGCCTGGTC
  CTGGAAAGTTTCAAGATCATGGACTACAGCCTGCTGCTGGGCGTGCACAACATCGACCAG
  CACGAGCGCGAGCGGCAGGCGCAGGGCGCCCAGAGCACCTCAGATGAGAAGCGGCCTGTG
  GGCCAGAAGGCGCTCTACTCCACGGCCATGGAGTCCATCCAGGGTGGCGCCGCGCGCGGG
  GAGGCCATCGAATCGGATGACACGATGGGCGGGATCCCCGCTGTGAACGGCCGCGGGGAG
  CGGCTGCTGCTGCACATTGGCATCATCGACATCCTGCAGTCCTACAGGTTCATCAAGAAA
  CTGGAGCACACCTGGAAGGCCCTCGTCCACGATGGGGACACGGTGTCCGTCCACCGCCCC
  AGCTTCTATGCCGAGCGCTTTTTCAAGTTCATGAGCAACACGGTCTTTCGGAAGAACTCC
  TCCCTGAAGTCCTCGCCCTCCAAGAAGGGGCGCGGCGGAGCCTTGCTAGCTGTGAAACCG
  CTGGGGCCCACCGCTGCCTTCTCGGCCAGCCAGATCCCTAGCGAGCGGGAGGAGGCCCAG
  TACGACCTGCGGGGGGCCCGCAGCTACCCCACGCTGGAGGACGAAAGCCGGCCCGACCTC
  CTGCCCTGCACGCCACCTTCTTTCGAAGAAGCCACTACAGCCTCCATTGCCACGACTCTG
  TCATCCACATCCCTCTCCATTCCTGAGCGGTCCCCCTCGGAGACGTCGGAGCAGCCGCGG
  TACAGGCGGCGCACACAGTCGTCTGGACAGGATGGCAGGCCGCAGGAGGAGCCACCCGCG
  GAAGAGGATCTGCAGCAGATTACAGTGCAGGTGGAGCCTGCGTGCAGCGTGGAGATTGTG
  GTCCCCAAAGAGGAGGACGCAGGGGTGGAGGCTTCCCCGGCCGGTGCCTCTGCTGCTGTT
  GAAGTAGAAACTGCCAGCCAGGCCTCAGACGAGGAGGGCGCACCTGCCAGCCAGGCCTCG
  GACGAGGAGGACGCGCCCGCCACCGACATCTACTTTCCCACCGATGAGAGGAGCTGGGTG
  TACTCCCCGCTCCACTATAGCGCCCAGGCCCCCCCGGCCTCCGACGGCGAGAGCGACACA
  TAATTTCTATGCAGCCCCCGACCCAGAGCCGAGCTCCACTTCTGCTCCGGCTGCCCCCGA
  AGGCGCTGCCCACCCCGCTGAGGCCCAGAGCTCGGGAGATGCCCGCCTCGCCGCCCCACC
  GGACCTCGTCCTCCCCCTGCACGGATGCCGACGGCCGGGCCCCTCCCCGACAAGCCTCCC
  AGGGCCCCGGCACCCCGGTCGGCAGCCTGCCCCTGTGAGATCCACCCTCCCG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012398 unedited
  CTGAATTCCCCGCCCGTTGCACCCATAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATAT
  AAGCAGTATCTGGGTTAGGTGACACTATAAAAACCAAGCTACTTGTTCTTTTTGCAGCGG
  CCGCGAATTCGGCACGAGGCAGCTCGGGTCCCCCTCGGGCGCCCCCGCCGCCGTCCGCGC
  GCGGCCATGGAGCTGGAGGTACCGGACGAGGCGGAGAGCGCTGAGGCGGGGGCCGTGCCC
  TCGGAGGCGGCGTGGGCGGCAGAGAGCGGGGCGGCGGCAGGTTTGGCTCAGAAGAAGGCG
  GCCCCAACAGAGGTTCTGTCCATGACGGCACAGCCGGGCCCTGGCCATGGGAAGAAGTTG
  GGCCATCGAGGTGTGGACGCATCCGGCGAAACCACCTACAAGAAGACCACCTCCTCCACC
  CTGAAGGGTGCCATCCAGCTGGGCATCGGCTACACCGTGGGCCACCTGAGCTCCAAGCCC
  GAACGCGACGTGCTCATGCAGGACTTCTACGTGGTGGAGAGCATCTTCTTCCCCAGCGAA
  GGCAGCAACCTCACCCCCGCCCACCACTTCCAGGACTTCCGCTTCAAGACCTATGCACCT
  GTCGCCTTCCGCTACTTCCGGGAGCTCTTTGGGATCCGGCCAGATGATTACTTGTACTCC
  CTGTGCAATGAGCCGCTGATCGAGCTGTCCAACCCGGGCGCCAGTGGCTCCCTCTTCTAC
  GTCACCAGCGACGACGAGTTCATCATCAAGACCGTCATGCACAANGGAGCCCGAGTTCCT
  GCAGAAGCTGCTCCCTGGCTACTACATGAAACCTCANCCAGGACCCCGCGGGACGCTGCT
  TGCCCAAGTTCTATGGGCTGGACTGCGTGCAGTCAGGGGGCAAGAACATTCGCGTCGTGG
  TCATGAACAACATCCTGCCCGGCGTGGTCAAAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012398
• ORF Size: 2007 bp
• Insert Size: 6000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012398.1, NP_036530.1
• RefSeq Size: 5047
• RefSeq ORF: 2007
• Locus ID: 23396
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis, Fc gamma R-mediated phagocytosis, Focal adhesion, Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, Regulation of actin cytoskeleton
• Gene Summary: This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2010]
  Transcript Variant: This variant (2) contains an alternate, in-frame exon in the 3' coding region compared to variant 1. The encoded isoform (2, also known as PIPKIgamma668 and PIPKIgamma90) is longer and has a distinct C-terminus, compared to isoform 1.