POLDIP1 (KCTD13) (NM_178863) Human Untagged Clone

CAT#: SC107237

KCTD13 (untagged)-Human potassium channel tetramerisation domain containing 13 (KCTD13)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCTD13
• Synonyms: BACURD1; FKSG86; hBACURD1; PDIP1; POLDIP1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_178863, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCGGCGGAGGCCTCGGGCCCGGCTGCCGCCGCGGCCCCGTCCCTGGAAGCCCCCAAGCCCTCGGGTC
  TCGAGCCTGGCCCCGCCGCCTACGGTCTCAAGCCGCTGACCCCGAACAGCAAATACGTGAAGCTGAACGT
  GGGCGGCTCGTTGCACTACACCACGCTGCGCACCCTCACGGGACAGGACACCATGCTCAAAGCCATGTTC
  AGCGGCCGCGTGGAGGTGCTGACCGATGCCGGAGGTTGGGTGCTGATTGACCGGAGCGGCCGTCACTTTG
  GTACAATCCTCAATTACCTGCGGGATGGGTCTGTGCCACTGCCGGAGAGTACGAGAGAACTGGGGGAGCT
  GCTGGGCGAAGCACGCTACTACCTGGTGCAGGGCCTGATTGAGGACTGCCAGCTGGCGCTGCAGCAAAAA
  AGGGAGACGCTGTCCCCGCTGTGCCTCATCCCCATGGTGACATCTCCCCGGGAGGAGCAGCAGCTCCTGG
  CCAGCACCTCCAAGCCCGTGGTGAAGCTCCTGCACAACCGCAGTAACAACAAGTACTCCTACACCAGCAC
  TTCAGATGACAACCTACTTAAGAACATCGAGCTGTTCGACAAGCTGGCCCTGCGCTTCCACGGGCGGCTA
  CTCTTCCTCAAGGATGTCCTGGGGGACGAGATCTGCTGCTGGTCTTTCTACGGGCAGGGCCGCAAAATCG
  CCGAGGTGTGCTGCACCTCCATTGTCTATGCTACGGAGAAGAAGCAGACCAAGGTGGAATTTCCAGAGGC
  CCGGATCTTCGAGGAGACCCTGAACATCCTCATCTACGAGACTCCCCGGGGCCCAGACCCAGCCCTCCTG
  GAGGCCACAGGGGGAGCAGCTGGAGCTGGTGGGGCTGGCCGCGGGGAGGATGAAGAGAACCGAGAGCACC
  GTGTCCGCAGGATCCATGTCCGGCGCCATATCACCCACGACGAGCGTCCTCATGGCCAACAAATTGTCTT
  CAAGGACTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_178863 unedited
  GGAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCGCCGAGCGGTCT
  GGCCCAAGGCTGGGGGCCGGCCGAGGGTCTTCGGGAGCAGGCCGCAGGGCGCGGAGAGAT
  CCTGGGATCGCCGTCCGCCGCTGCTACCCGGCATGTCGGCGGAGGCCTCGGGCCCGGCTG
  CCGCCGCGGCCCCGTCCCTGGAAGCCCCCAAGCCCTCGGGTCTCGAGCCTGGCCCCGCCG
  CCTACGGTCTCAAGCCGCTGACCCCGAACAGCAAATACGTGAAGCTGAACGTGGGCGGCT
  CGTTGCACTACACCACGCTGCGCACCCTCACGGGACAGGACACCATGCTCAAAGCCATGT
  TCAGCGGCCGCGTGGAGGTGCTGACCGATGCCGGAGGTTGGGTGCTGATTGACCGGAGCG
  GCCGTCACTTTGGTACAATCCTCAATTACCTGCGGGATGGGTCTGTGCCACTGCCGGAGA
  GTACGAGAGAACTGGGGGAGCTGCTGGGCGAAGCACGCTACTACCTGGTGCAGGGCCTGA
  TTGAGGACTGCCAGCTGGCGCTGCAGCAAAAAAGGGAGACGCTGTCCCCGCTGTGCCTCA
  TCCCCATGGTGACATCTCCCCGGGAGGAGCAGCAGCTCCTGGCCAGCACCTNCAAGCCCG
  TGGTGAAGCTCCTGCANCACCGCAGTAACAACAAGTACTCCTACACCAGCACTTCAGATG
  ACAACCTACTTAAAGACATCGAGCTGTTCGACAAGCTGGCCCTGCGCCTTCACGGGCGGC
  TACTCTTNCTCAAGGATGTCCTGGGGGACGAGATCTGCTGCTGGTCTTTCTACGGGCAGG
  GCCGCAAATCGCCCGAGTTGTGCTGCACCTCCATGNCTATGCTCNGANAATAAGCAGACA
  TGATGGATTNCAGAGCCCGGATCTTGAGAGACCTGACTNCTCTCTACAGACTCCCGGGCC
  ATACCANCCTCTGAGCCCGGNGGACACTGNACTGTGGGCTGCCGCGGGAGATGAAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_178863 unedited
  GAGTTTTTTTTTTTGTTTTTTGTTTCTCAACTTAACTTTATTTCAATAATTTAATAGAAA
  ATTAAAATAATAAATAATATGAAACAGACTGATAACGCTGAGCTGGGCAGGCCCAGGCCA
  GTCTAGTACAAAGTTAAGGAGGTAGGGAGGATGGTGGGGAGGAGGGNTCNGACTACCCTG
  CCNGGCGCCGTATGCTTCTCTAACTGTGCTGCTGTCTAGTTGGGCCTCTCACTTTGGCAC
  CGGCGCTGCACTACATTTATATTAATGGTATTCTAGATCCCTCTTCCCCGCTCTGAGATC
  TAGGCCCCATGTCCCCCGGGGCACCATTTCTGGCTTCCTAAGGCCTTGATTCGCTTGGCC
  CAGTTGTCCCCCTGTTCCCTATCCATTGGGCTCTGGGTCCCCGGTGGATACCCGGCCCTT
  TATAGGTCCTTTGCCCAAGCCCATGTTACGCTTCCTTGGCTAGGACCCCTGCTACCTTTG
  TGCCCTCCAAGATTCTCTTTGGCACGAAAGCTCTCTGGACAAGACGCCCCCGTCATGGCA
  CATTCAGTCGACTTCGGATCCCCCACCGTGCTTTGGCCCTTCTGGCCTCTCGATCCCGGG
  ACCCAAAGGTCCATTTCCTCTGTCTTACCCTTCCTCTCTTCTCTTGTGGGCGCCCCACAA
  CATCCGCGGTTATTGTCTCAGCCCCAAAGATTCCTTTTCTCCCGCCGTCCTCGGTTATTC
  CAACATTCCCGAGCCTCTCCTCCCCGACTGTTCCCTCGCCTTGCCACCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_178863
• ORF Size: 990 bp
• Insert Size: 1800
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_178863.2, NP_849194.1
• RefSeq Size: 1750
• RefSeq ORF: 990
• Locus ID: 253980
• Protein Families: Ion Channels: Other, Transcription Factors
• Gene Summary: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:19782033). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome (PubMed:19782033) Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) encodes the supported protein.