MARK4 (NM_031417) Human Untagged Clone

CAT#: SC107258

MARK4 (untagged)-Human MAP/microtubule affinity-regulating kinase 4 (MARK4), transcript variant 2


  "NM_031417" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol MARK4
Synonyms MARK4L; MARK4S; MARKL1; MARKL1L; PAR-1D
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_031417, the custom clone sequence may differ by one or more nucleotides


ATGTCTTCGCGGACGGTGCTGGCCCCGGGCAACGATCGGAACTCGGACACGCATGGCACCTTGGGCAGTG
GCCGCTCCTCGGACAAAGGCCCGTCCTGGTCCAGCCGCTCACTGGGTGCCCGTTGCCGGAACTCCATCGC
CTCCTGTCCCGAGGAGCAGCCCCACGTGGGCAACTACCGCCTGCTGAGGACCATTGGGAAGGGCAACTTT
GCCAAAGTCAAGCTGGCTCGGCACATCCTCACTGGTCGGGAGGTTGCCATCAAGATTATCGACAAAACCC
AGCTGAATCCCAGCAGCCTGCAGAAGCTGTTCCGAGAAGTCCGCATCATGAAGGGCCTAAACCACCCCAA
CATCGTGAAGCTCTTTGAGGTGATTGAGACTGAGAAGACGCTGTACCTGGTGATGGAGTACGCAAGTGCT
GGAGAAGTGTTTGACTACCTCGTGTCGCATGGCCGCATGAAGGAGAAGGAAGCTCGAGCCAAGTTCCGAC
AGATTGTTTCGGCTGTGCACTATTGTCACCAGAAAAATATTGTACACAGGGACCTGAAGGCTGAGAACCT
CTTGCTGGATGCCGAGGCCAACATCAAGATTGCTGACTTTGGCTTCAGCAACGAGTTCACGCTGGGATCG
AAGCTGGACACGTTCTGCGGGAGCCCCCCATATGCCGCCCCGGAGCTGTTTCAGGGCAAGAAGTACGACG
GGCCGGAGGTGGACATCTGGAGCCTGGGAGTCATCCTGTACACCCTCGTCAGCGGCTCCCTGCCCTTCGA
CGGGCACAACCTCAAGGAGCTGCGGGAGCGAGTACTCAGAGGGAAGTACCGGGTCCCTTTCTACATGTCA
ACAGACTGTGAGAGCATCCTGCGGAGATTTTTGGTGCTGAACCCAGCTAAACGCTGTACTCTCGAGCAAA
TCATGAAAGACAAATGGATCAACATCGGCTATGAGGGTGAGGAGTTGAAGCCATACACAGAGCCCGAGGA
GGACTTCGGGGACACCAAGAGAATTGAGGTGATGGTGGGTATGGGCTACACACGGGAAGAAATCAAAGAG
TCCTTGACCAGCCAGAAGTACAACGAAGTGACCGCCACCTACCTCCTGCTGGGCAGGAAGACTGAGGAGG
GTGGGGACCGGGGCGCCCCAGGGCTGGCCCTGGCACGGGTGCGGGCGCCCAGCGACACCACCAACGGAAC
AAGTTCCAGCAAAGGCACCAGCCACAGCAAAGGGCAGCGGAGTTCCTCTTCCACCTACCACCGCCAGCGC
AGGCATAGCGATTTCTGTGGCCCATCCCCTGCACCCCTGCACCCCAAACGCAGCCCGACGAGCACGGGGG
AGGCGGAGCTGAAGGAGGAGCGGCTGCCAGGCCGGAAGGCGAGCTGCAGCACCGCGGGGAGTGGGAGTCG
AGGGCTGCCCCCCTCCAGCCCCATGGTCAGCAGCGCCCACAACCCCAACAAGGCAGAGATCCCAGAGCGG
CGGAAGGACAGCACGAGCACCCCCAACAACCTCCCTCCTAGCATGATGACCCGCAGAAACACCTACGTTT
GCACAGAACGCCCGGGGGCTGAGCGCCCGTCACTGTTGCCAAATGGGAAAGAAAACAGCTCAGGCACCCC
ACGGGTGCCCCCTGCCTCCCCCTCCAGTCACAGCCTGGCACCCCCATCAGGGGAGCGGAGCCGCCTGGCA
CGCGGTTCCACCATCCGCAGCACCTTCCATGGTGGCCAGGTCCGGGACCGGCGGGCAGGGGGTGGGGGTG
GTGGGGGTGTGCAGAATGGGCCCCCTGCCTCTCCCACACTGGCCCATGAGGCTGCACCCCTGCCCGCCGG
GCGGCCCCGCCCCACCACCAACCTCTTCACCAAGCTGACCTCCAAACTGACCCGAAGGGTTACCCTCGAT
CCCTCTAAACGGCAGAACTCTAACCGCTGTGTTTCGGGCGCCTCTCTGCCCCAGGGATCCAAGATCAGGT
CGCAGACGAACCTGAGAGAATCGGGGGACCTGAGGTCACAAGTTGCCATCTACCTTGGGATCAAACGGAA
ACCGCCCCCCGGCTGCTCCGATTCCCCTGGAGTGTGA


>OriGene 5' read for NM_031417 unedited
CGGTTTTCGGGCAGTGNCTGGCCCCCGGTTCAACNTNCGGNAACTCGCCACGCATGGCAC
CTTGGGCAGTGGCCGCTCCTCGGNCAAAGGCCCGTCCTGGTCCAGCCGCTCACTGGGTGC
CCGTTGCCGGAACTCCATCGCCTCCTGTCCCGAGGAGCAGCCCCACGTGGGCAACTACCG
CCTGCTGAGGACCATTGGGAAGGGCAACTTTGCCAAAGTCAAGCTGGCTCGGCACATCCT
CACTGGTCGGGAGGTTGCCATCAAGATTATCGACAAAACCCAGCTGAATCCCAGCAGCCT
GCAGAAGCTGTTCCGAGAAGTCCGCATCATGAAGGGCCTAAACCACCCCAACATCGTGAA
GCTCTTTGAGGTGATTGAGACTGAGAAGACGCTGTACCTGGTGATGGAGTACGCAAGTGC
TGGAGAAGTGTTTGACTACCTCGTGTCGCATGGCCGCATGAAGGAGAAGGAAGCTCGAGC
CAAGTTCCGACAGATTGTTTCGGCTGTGCACTATTGTCACCAGAAAAATATTGTACACAG
GGACCTGAAGGCTGAGAACCTCTTGCTGGATGCCGAGGCCAACATCAAGATTGCTGACTT
TGGCTTCAGCAACGAGTTCACGCTGGGATCGAAGCTGGACACGTTCTGCGGGAGCCCCCC
ATATGCCGCCCCGGAGCTGTTTCAGGGCAAGAAGTACGACGGGCCGGGAGTGGACATCTG
GAGCCTGGGAGTCATCCTGTACACCCTCGTCAGCGGCTCCCTGCCCTTCGACGGGCACAA
CCTCAAAGAGCTGCGGGAGCGAGTACTCAGAGGGAAGTACGGGGTCCCTTTCTACATGTC
AACAGACTGTGAGAGCATCCTGCGGAGAATTTTGGTGCTGAACCCAGCTAAACGCTGTAC
TCTCGAGCAATCATGAAAGACAATGGAT
>OriGene 3' read for NM_031417 unedited
NNAAATTACTTGNACCGCGCCGCTTTCNANNGATCGGTTTTTTTTTTTTTTTTTTTTTTT
GGGGAGGGGGGGACTCTCTTAAATTATTGGGCAACAGGCTGCAGGTGAGGGGGCTGACAG
GAGGAGGGTCGGGGTGTAATAACTTAAAAACCGTAGGTGACAGCGGCAGCTCCTCAAGAG
ACCTTTGCAGAGGGGAGGGTGTGGGGTATTTACAAGGATTTGTACAAAGTGCCCCGCGCC
AGCCTGGGGCAGGAAGTGGGGGTTTGAGCGTGAGGGGACGGGAGGGGAAGGAATCTGCCT
CTCTGACCCCCACTCCCAGTCCCCCAGATTCTCCAGTCTTTAGGCTCAGCAGCTCTCCCT
GCCCCTGCCCAAGGCCTAATTTTGAGCTGTTGGGAGGAATGGAAGATTTCCTCAGTTTCC
CTCCCTGCCCCTGCCCTGTCCCCAAAGTCTCCTCAGGTGCCCTCTTGGTAGGGCGAGGGA
GGACAGGACTGGCTGGAGGCTCCAGGAAGGTGCCAGCTCCCCCCGCTGAGCCCCCTCATC
CTTCTTCTGTGCTGAGCGGCCCCAGAGAACAGCAGAGGGGACAATCTTTGCCCCCAAATA
TAATTCANGGAAACTGAGGTGATGATAAAGGGAGAATCCCCTCCCTGGCCCCTTCCCCTC
CTGTAGAAGTGAANGCGACAAGGGAGAAGGAAGAGTAAGGGCCCTGGGGACCGTGGTGGC
TCAGAGCTCGAGGTCGTTTGAAGATGCGGGTGACAAGGGTGCCGAAGGCCAGGGCGGTGC
CCGCCACACCGCGGAAGAGAACTCCCCGCAAGCCTGGCCCGGGCAGCTTGGCAAACCTCC
ACTCCAAATTGGGACAAGGGCTTGGGGCCCCGCCCGACCCCCGTGCAGGCAGGCCCAACA
GAAACGGTTTGGGCTGGCGGCCACCGGCC
Restriction Sites Please inquire     
ACCN NM_031417
ORF Size 2067 bp
Insert Size 5000
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_031417.2, NP_113605.2
RefSeq Size 4917
RefSeq ORF 2067
Locus ID 57787
Protein Families Druggable Genome, Protein Kinase
Gene Summary This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Transcript Variant: This variant (2) includes an alternate exon, which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus, compared to isoform 1.

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