MARK4 (NM_031417) Human Untagged Clone

CAT#: SC107258

MARK4 (untagged)-Human MAP/microtubule affinity-regulating kinase 4 (MARK4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MARK4
• Synonyms: MARK4L; MARK4S; MARKL1; MARKL1L; PAR-1D
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031417, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCTTCGCGGACGGTGCTGGCCCCGGGCAACGATCGGAACTCGGACACGCATGGCACCTTGGGCAGTG
  GCCGCTCCTCGGACAAAGGCCCGTCCTGGTCCAGCCGCTCACTGGGTGCCCGTTGCCGGAACTCCATCGC
  CTCCTGTCCCGAGGAGCAGCCCCACGTGGGCAACTACCGCCTGCTGAGGACCATTGGGAAGGGCAACTTT
  GCCAAAGTCAAGCTGGCTCGGCACATCCTCACTGGTCGGGAGGTTGCCATCAAGATTATCGACAAAACCC
  AGCTGAATCCCAGCAGCCTGCAGAAGCTGTTCCGAGAAGTCCGCATCATGAAGGGCCTAAACCACCCCAA
  CATCGTGAAGCTCTTTGAGGTGATTGAGACTGAGAAGACGCTGTACCTGGTGATGGAGTACGCAAGTGCT
  GGAGAAGTGTTTGACTACCTCGTGTCGCATGGCCGCATGAAGGAGAAGGAAGCTCGAGCCAAGTTCCGAC
  AGATTGTTTCGGCTGTGCACTATTGTCACCAGAAAAATATTGTACACAGGGACCTGAAGGCTGAGAACCT
  CTTGCTGGATGCCGAGGCCAACATCAAGATTGCTGACTTTGGCTTCAGCAACGAGTTCACGCTGGGATCG
  AAGCTGGACACGTTCTGCGGGAGCCCCCCATATGCCGCCCCGGAGCTGTTTCAGGGCAAGAAGTACGACG
  GGCCGGAGGTGGACATCTGGAGCCTGGGAGTCATCCTGTACACCCTCGTCAGCGGCTCCCTGCCCTTCGA
  CGGGCACAACCTCAAGGAGCTGCGGGAGCGAGTACTCAGAGGGAAGTACCGGGTCCCTTTCTACATGTCA
  ACAGACTGTGAGAGCATCCTGCGGAGATTTTTGGTGCTGAACCCAGCTAAACGCTGTACTCTCGAGCAAA
  TCATGAAAGACAAATGGATCAACATCGGCTATGAGGGTGAGGAGTTGAAGCCATACACAGAGCCCGAGGA
  GGACTTCGGGGACACCAAGAGAATTGAGGTGATGGTGGGTATGGGCTACACACGGGAAGAAATCAAAGAG
  TCCTTGACCAGCCAGAAGTACAACGAAGTGACCGCCACCTACCTCCTGCTGGGCAGGAAGACTGAGGAGG
  GTGGGGACCGGGGCGCCCCAGGGCTGGCCCTGGCACGGGTGCGGGCGCCCAGCGACACCACCAACGGAAC
  AAGTTCCAGCAAAGGCACCAGCCACAGCAAAGGGCAGCGGAGTTCCTCTTCCACCTACCACCGCCAGCGC
  AGGCATAGCGATTTCTGTGGCCCATCCCCTGCACCCCTGCACCCCAAACGCAGCCCGACGAGCACGGGGG
  AGGCGGAGCTGAAGGAGGAGCGGCTGCCAGGCCGGAAGGCGAGCTGCAGCACCGCGGGGAGTGGGAGTCG
  AGGGCTGCCCCCCTCCAGCCCCATGGTCAGCAGCGCCCACAACCCCAACAAGGCAGAGATCCCAGAGCGG
  CGGAAGGACAGCACGAGCACCCCCAACAACCTCCCTCCTAGCATGATGACCCGCAGAAACACCTACGTTT
  GCACAGAACGCCCGGGGGCTGAGCGCCCGTCACTGTTGCCAAATGGGAAAGAAAACAGCTCAGGCACCCC
  ACGGGTGCCCCCTGCCTCCCCCTCCAGTCACAGCCTGGCACCCCCATCAGGGGAGCGGAGCCGCCTGGCA
  CGCGGTTCCACCATCCGCAGCACCTTCCATGGTGGCCAGGTCCGGGACCGGCGGGCAGGGGGTGGGGGTG
  GTGGGGGTGTGCAGAATGGGCCCCCTGCCTCTCCCACACTGGCCCATGAGGCTGCACCCCTGCCCGCCGG
  GCGGCCCCGCCCCACCACCAACCTCTTCACCAAGCTGACCTCCAAACTGACCCGAAGGGTTACCCTCGAT
  CCCTCTAAACGGCAGAACTCTAACCGCTGTGTTTCGGGCGCCTCTCTGCCCCAGGGATCCAAGATCAGGT
  CGCAGACGAACCTGAGAGAATCGGGGGACCTGAGGTCACAAGTTGCCATCTACCTTGGGATCAAACGGAA
  ACCGCCCCCCGGCTGCTCCGATTCCCCTGGAGTGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_031417 unedited
  CGGTTTTCGGGCAGTGNCTGGCCCCCGGTTCAACNTNCGGNAACTCGCCACGCATGGCAC
  CTTGGGCAGTGGCCGCTCCTCGGNCAAAGGCCCGTCCTGGTCCAGCCGCTCACTGGGTGC
  CCGTTGCCGGAACTCCATCGCCTCCTGTCCCGAGGAGCAGCCCCACGTGGGCAACTACCG
  CCTGCTGAGGACCATTGGGAAGGGCAACTTTGCCAAAGTCAAGCTGGCTCGGCACATCCT
  CACTGGTCGGGAGGTTGCCATCAAGATTATCGACAAAACCCAGCTGAATCCCAGCAGCCT
  GCAGAAGCTGTTCCGAGAAGTCCGCATCATGAAGGGCCTAAACCACCCCAACATCGTGAA
  GCTCTTTGAGGTGATTGAGACTGAGAAGACGCTGTACCTGGTGATGGAGTACGCAAGTGC
  TGGAGAAGTGTTTGACTACCTCGTGTCGCATGGCCGCATGAAGGAGAAGGAAGCTCGAGC
  CAAGTTCCGACAGATTGTTTCGGCTGTGCACTATTGTCACCAGAAAAATATTGTACACAG
  GGACCTGAAGGCTGAGAACCTCTTGCTGGATGCCGAGGCCAACATCAAGATTGCTGACTT
  TGGCTTCAGCAACGAGTTCACGCTGGGATCGAAGCTGGACACGTTCTGCGGGAGCCCCCC
  ATATGCCGCCCCGGAGCTGTTTCAGGGCAAGAAGTACGACGGGCCGGGAGTGGACATCTG
  GAGCCTGGGAGTCATCCTGTACACCCTCGTCAGCGGCTCCCTGCCCTTCGACGGGCACAA
  CCTCAAAGAGCTGCGGGAGCGAGTACTCAGAGGGAAGTACGGGGTCCCTTTCTACATGTC
  AACAGACTGTGAGAGCATCCTGCGGAGAATTTTGGTGCTGAACCCAGCTAAACGCTGTAC
  TCTCGAGCAATCATGAAAGACAATGGAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_031417 unedited
  NNAAATTACTTGNACCGCGCCGCTTTCNANNGATCGGTTTTTTTTTTTTTTTTTTTTTTT
  GGGGAGGGGGGGACTCTCTTAAATTATTGGGCAACAGGCTGCAGGTGAGGGGGCTGACAG
  GAGGAGGGTCGGGGTGTAATAACTTAAAAACCGTAGGTGACAGCGGCAGCTCCTCAAGAG
  ACCTTTGCAGAGGGGAGGGTGTGGGGTATTTACAAGGATTTGTACAAAGTGCCCCGCGCC
  AGCCTGGGGCAGGAAGTGGGGGTTTGAGCGTGAGGGGACGGGAGGGGAAGGAATCTGCCT
  CTCTGACCCCCACTCCCAGTCCCCCAGATTCTCCAGTCTTTAGGCTCAGCAGCTCTCCCT
  GCCCCTGCCCAAGGCCTAATTTTGAGCTGTTGGGAGGAATGGAAGATTTCCTCAGTTTCC
  CTCCCTGCCCCTGCCCTGTCCCCAAAGTCTCCTCAGGTGCCCTCTTGGTAGGGCGAGGGA
  GGACAGGACTGGCTGGAGGCTCCAGGAAGGTGCCAGCTCCCCCCGCTGAGCCCCCTCATC
  CTTCTTCTGTGCTGAGCGGCCCCAGAGAACAGCAGAGGGGACAATCTTTGCCCCCAAATA
  TAATTCANGGAAACTGAGGTGATGATAAAGGGAGAATCCCCTCCCTGGCCCCTTCCCCTC
  CTGTAGAAGTGAANGCGACAAGGGAGAAGGAAGAGTAAGGGCCCTGGGGACCGTGGTGGC
  TCAGAGCTCGAGGTCGTTTGAAGATGCGGGTGACAAGGGTGCCGAAGGCCAGGGCGGTGC
  CCGCCACACCGCGGAAGAGAACTCCCCGCAAGCCTGGCCCGGGCAGCTTGGCAAACCTCC
  ACTCCAAATTGGGACAAGGGCTTGGGGCCCCGCCCGACCCCCGTGCAGGCAGGCCCAACA
  GAAACGGTTTGGGCTGGCGGCCACCGGCC
  
• Restriction Sites: Please inquire
• ACCN: NM_031417
• ORF Size: 2067 bp
• Insert Size: 5000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_031417.2, NP_113605.2
• RefSeq Size: 4917
• RefSeq ORF: 2067
• Locus ID: 57787
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
  Transcript Variant: This variant (2) includes an alternate exon, which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus, compared to isoform 1.