IKB zeta (NFKBIZ) (NM_031419) Human Untagged Clone

CAT#: SC107269

NFKBIZ (untagged)-Human nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (NFKBIZ), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NFKBIZ
• Synonyms: IKBZ; INAP; MAIL
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031419, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATTGTGGACAAGCTGCTGGACGACAGCCGCGGCGGAGAGGGGCTGCGGGACGCGGCGGGCGGCTGCG
  GCCTCATGACCAGCCCGCTCAACCTGAGCTACTTCTACGGCGCGTCGCCGCCCGCCGCCGCCCCGGGCGC
  CTGCGACGCCAGCTGCTCGGTCTTGGGCCCCTCGGCGCCCGGCTCGCCCGGCTCCGACTCCTCCGACTTC
  TCCTCTGCCTCGTCGGTGTCCTCCTGCGGCGCCGTGGAGTCCCGGTCGAGAGGCGGCGCCCGCGCCGAGC
  GCCAGCCAGTTGAGCCCCATATGGGGGTTGGCAGGCAGCAGAGAGGCCCCTTTCAAGGTGTTCGGGTAAA
  GAACTCAGTGAAGGAACTCCTGTTGCACATCCGAAGTCATAAACAGAAGGCTTCTGGCCAAGCTGTGGAT
  GATTTTAAGACACAAGGTGTGAACATAGAACAGTTCAGAGAATTGAAGAACACAGTATCATACAGTGGGA
  AAAGGAAAGGGCCCGATTCGTTGTCTGATGGACCTGCTTGCAAAAGGCCAGCTCTGTTGCATTCCCAATT
  TTTGACACCACCTCAAACACCAACGCCCGGGGAGAGCATGGAAGATGTTCATCTCAATGAACCCAAACAG
  GAGAGCAGTGCTGATCTGCTTCAGAACATTATCAACATTAAGAATGAATGCAGCCCCGTTTCCCTGAACA
  CAGTTCAAGTTAGCTGGCTGAACCCCGTGGTGGTCCCTCAGAGCTCCCCCGCAGAGCAGTGTCAGGACTT
  CCATGGAGGGCAGGTCTTTTCTCCACCTCAGAAATGCCAACCATTCCAAGTCAGGGGCTCCCAACAAATG
  ATAGACCAGGCTTCCCTGTACCAGTATTCTCCACAGAACCAGCATGTAGAGCAGCAGCCACACTACACCC
  ACAAACCAACTCTGGAATACAGTCCTTTTCCCATACCTCCCCAGTCCCCCGCTTATGAACCAAACCTCTT
  TGATGGTCCAGAATCACAGTTTTGCCCAAACCAAAGCTTAGTTTCCCTTCTTGGTGATCAAAGGGAATCT
  GAGAATATTGCTAATCCCATGCAGACTTCCTCCAGTGTTCAGCAGCAAAATGATGCTCACTTGCACAGCT
  TCAGCATGATGCCCAGCAGCGCCTGTGAGGCCATGGTGGGGCACGAGATGGCCTCTGACTCTTCAAACAC
  TTCACTGCCATTCTCAAACATGGGAAATCCAATGAACACCACACAGTTAGGGAAATCACTTTTTCAGTGG
  CAGGTGGAGCAGGAAGAAAGCAAATTGGCAAATATTTCCCAAGACCAGTTTCTTTCAAAGGATGCAGATG
  GTGACACGTTCCTTCATATTGCTGTTGCCCAAGGGAGAAGGGCACTTTCCTATGTTCTTGCAAGAAAGAT
  GAATGCACTTCACATGCTGGATATTAAAGAGCACAATGGACAGAGTGCCTTTCAGGTGGCAGTGGCTGCC
  AATCAGCATCTCATTGTGCAGGATCTGGTGAACATCGGGGCACAGGTGAACACCACAGACTGCTGGGGAA
  GAACACCTCTGCATGTGTGTGCTGAGAAGGGCCACTCCCAGGTGCTTCAGGCGATTCAGAAGGGAGCAGT
  GGGAAGTAATCAGTTTGTGGATCTTGAGGCAACTAACTATGATGGCCTGACTCCCCTTCACTGTGCAGTC
  ATAGCCCACAATGCTGTGGTCCATGAACTCCAGAGAAATCAACAGCCTCATTCACCTGAAGTTCAGGAGC
  TTTTACTGAAGAATAAGAGTCTGGTTGATACCATTAAGTGCCTAATTCAAATGGGAGCAGCGGTGGAAGC
  GAAGGATCGCAAAAGTGGCCGCACAGCCCTGCATTTGGCAGCTGAAGAAGCAAATCTGGAACTCATTCGC
  CTCTTTTTGGAGCTGCCCAGTTGCCTGTCTTTTGTGAATGCAAAGGCTTACAATGGCAACACTGCCCTCC
  ATGTTGCTGCCAGCTTGCAGTATCGGTTGACACAATTAGATGCTGTCCGCCTGTTGATGAGGAAGGGAGC
  AGACCCAAGTACTCGGAACTTGGAGAACGAACAGCCAGTGCATTTGGTTCCCGATGGCCCTGTGGGAGAA
  CAGATCCGACGTATCCTGAAGGGAAAGTCCATTCAGCAGAGAGCTCCACCGTATTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_031419 unedited
  AAAAAAATAATAAAATTAATCAACAATCAGGTTCACATTTGTATACGATCATATAGGCGG
  CCGCGCGTCCGCCCGNCCGACGCTCCCTGAGCCAGCCCGGGAGGCAGCCGCGCGCAGCGA
  GCCGGTGGCGCAGGTGTCGGGGTCCTCGAGCGCCCAGCCTGGGAGCATGATTGTGGACAA
  GCTGCTGGACGACAGCCGCGGCGGAGAGGGGCTGCGGGACGCGGCGGGCGGCTGCGGCCT
  CATGACCAGCCCGCTCAACCTGAGCTACTTCTACGGCGCGTCGCCGCCCGCCGCCGCCCC
  GGGCGCCTGCGACGCCAGCTGCTCGGTCTTGGGCCCCTCGGCGCCCGGCTCGCCCGGCTC
  CGACTCCTCCGACTTCTCCTCTGCCTCGTCGGTGTCCTCCTGCGGCGCCGTGGAGTCCCG
  GTCGAGAGGCGGCGCCCGCGCCGAGCGCCAGCCAGTTGAGCCCCATATGGGGGTTGGCAG
  GCAGCAGAGAGGCCCCTTTCAAGGTGTTCGGGTAAAGAACTCAGTGAAGGAACTCCTGTT
  GCACATCCGAAGTCATAAACAGAAGGCTTCTGGCCAAGCTGTGGATGATTTTAAGACACA
  AGGTGTGAACATAGAACAGTTCAGAGAATCGAAGAACACAGTATCATACAGTGGGAAAAG
  GAAAGGGCCCGATTCGTTGTCTGATGGACCTGCTTGCAAAAGCCAGCTCTGTTGCATTCC
  CCATTTTTGACACCACCTTAAACACCAACGTCCCGGGGAGAGCATGGAAGATGTTCATCT
  CAATGAACCCAAACAGGAGAGCAGCGCTGATCTTGTTCCAAACCTTATCACCCATTAAGA
  ATGGATGCAGCCCCCGTTTCTCTGAAACCAGGTTAAGGTTAACTGGCCTGACCCCCGTGG
  GGGTCCCTCAAAGCTTCCCCCGAAACACTGTGTAGGACTTTCATGAAGGGCAGGGCTTCT
  TTCN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_031419 unedited
  TTTTTTTTTTTTTTTTTAATATAACCCACTATATAATAGTGAACTAAATATGTTTGTTTC
  ATAGAAACAACTTACATTTGCCAATATAAGGCAAATGGTCTATGTACAGATACATCAGGA
  CTGCCTAACTGACAGTGAGTGTTGCTAGCCAGGCTCCAAGCTAATGGAGCTAATACGGTG
  GAGCTCTCTGCTGAATGGACTTTCCCTTCAGGATACGTCGGATCTGTTCTCCCACAGGGC
  CATCGGGAACCAAATGCACTGGCTGTTCGTTCTCCAAGTTCCGAGTACTTGGGTCTGCTC
  CCTTCCTCATCAACAGGCGGACAGCATCTAATTGTGTCAACCGATACTGCAAGCTGGCAG
  CAACATGGAGGGCAGTGTTGCCATTGTAAGCCTTCGCTTCCACCGCTGCTCCCATTTGAA
  TTAGGCACTTAATGGTATCAACCAGACTCTTATTCTTCAGTAAAAGCTCCTGAACTTCAG
  GTGAATGAGGCTGTTGATTTCTCTGGGAGTCATGGACCACAGCATTTGTGGCTATGACTG
  CACAGTGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_031419
• ORF Size: 2157 bp
• Insert Size: 2500
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_031419.2, NP_113607.1
• RefSeq Size: 3934
• RefSeq ORF: 2157
• Locus ID: 64332
• Domains: ANK
• Protein Families: Druggable Genome
• Gene Summary: This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (a).