HACE1 (NM_020771) Human Untagged Clone

CAT#: SC107534

HACE1 (untagged)-Human HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (HACE1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HACE1
• Synonyms: SPPRS
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC107534 sequence for NM_020771 edited (data generated by NextGen Sequencing)
  ATGGAGAGAGCGATGGAGCAACTCAACCGCCTGACGCGCTCGCTGCGCCGCGCGCGCACC
  GTGGAGTTGCCCGAGGATAATGAAACTGCTGTTTATACATTAATGCCAATGGTTATGGCT
  GATCAACACAGGTCTGTTTCTGAACTACTATCAAATTCAAAATTTGATGTCAATTATGCA
  TTCGGACGTGTGAAAAGAAGCTTGCTTCACATTGCAGCAAATTGTGGATCGGTGGAATGC
  TTGGTTTTGCTGTTAAAGAAAGGAGCAAATCCTAACTATCAAGATATTTCAGGCTGTACA
  CCCCTTCATTTGGCAGCAAGAAATGGGCAGAAGAAATGTATGAGTAAATTATTAGAATAT
  AGCGCTGATGTCAACATTTGTAATAATGAAGGCCTTACAGCAATACATTGGCTGGCTGTG
  AATGGGCGGACAGAACTACTCCATGACCTTGTGCAGCATGTCAGTGATGTTGATGTTGAG
  GATGCCATGGGGCAGACAGCACTGCATGTTGCCTGCCAGAACGGTCACAAGACGACAGTG
  CAGTGCTTGCTAGACAGTGGTGCTGATATTAACAGGCCAAATGTATCAGGAGCAACTCCA
  TTGTACTTTGCTTGCAGTCATGGTCAGAGAGATACAGCACAGATCCTACTATTACGAGGA
  GCCAAATATCTGCCAGATAAAAATGGAGTAACTCCTCTGGATTTATGTGTACAGGGTGGA
  TATGGAGAGACTTGTGAAGTATTAATTCAATATCACCCGAGGCTTTTTCAGACTATTATT
  CAAATGACACAGAATGAAGACCTCCGAGAAAACATGTTACGGCAAGTTCTGGAGCATTTG
  TCTCAGCAAAGTGAAAGCCAGTACCTAAAGATTCTAACAAGCCTTGCTGAAGTTGCTACA
  ACAAATGGTCATAAACTGCTTAGCCTCTCTAGCAATTATGATGCTCAAATGAAGAGCCTT
  TTAAGGATTGTGAGAATGTTTTGTCACGTCTTTCGAATTGGTCCATCCTCCCCCAGTAAT
  GGAATTGATATGGGCTACAATGGGAATAAAACTCCAAGAAGCCAGGTGTTCAAGCCTCTG
  GAATTGCTTTGGCACTCGTTAGATGAATGGCTAGTTTTAATAGCCACAGAATTGATGAAA
  AACAAAAGAGACTCAACAGAGATCACTTCTATTTTACTGAAACAAAAAGGCCAAGATCAA
  GATGCTGCTTCCATTCCTCCATTTGAACCTCCAGGACCTGGGAGCTATGAAAATCTGTCC
  ACTGGCACAAGGGAATCTAAACCAGATGCTCTTGCAGGGAGACAGGAAGCCAGTGCAGAT
  TGTCAGGATGTTATTTCTATGACAGCTAACCGGCTAAGTGCTGTCATTCAAGCTTTTTAC
  ATGTGCTGTTCTTGTCAGATGCCTCCGGGAATGACTTCACCTCGTTTCATTGAATTTGTC
  TGCAAACATGATGAAGTTTTAAAATGCTTTGTTAATAGAAATCCCAAAATTATATTTGAC
  CACTTTCACTTTCTCCTTGAATGTCCTGAGTTGATGTCAAGATTCATGCATATCATAAAA
  GCACAGCCTTTTAAAGATCGCTGTGAATGGTTCTATGAACATTTGCATTCAGGACAGCCA
  GATTCAGATATGGTGCACAGGCCAGTGAATGAAAATGATATCCTGCTGGTTCACAGAGAT
  TCTATTTTTAGGAGTAGCTGTGAAGTTGTGTCAAAAGCAAATTGTGCAAAGCTAAAGCAA
  GGGATTGCTGTACGGTTCCATGGAGAAGAAGGCATGGGTCAAGGTGTTGTGCGTGAGTGG
  TTTGATATTCTGTCCAATGAGATAGTCAATCCTGATTATGCATTGTTTACCCAGTCAGCT
  GATGGAACAACTTTTCAGCCTAATAGCAACTCTTATGTAAATCCTGATCACTTGAACTAT
  TTTCGGTTTGCTGGGCAGATCTTGGGATTAGCGTTGAACCACAGGCAGCTGGTCAATATT
  TACTTCACACGATCCTTCTACAAGCACATTCTTGGTATTCCTGTAAATTACCAAGATGTG
  GCATCCATTGATCCAGAATATGCGAAAAATTTGCAATGGATTTTAGATAATGATATAAGT
  GATCTGGGTCTAGAACTAACTTTTTCTGTTGAGACTGATGTGTTTGGAGCAATGGAAGAG
  GTGCCTTTGAAACCTGGGGGTGGGAGTATTCTTGTGACACAAAATAATAAAGCGGAGTAC
  GTCCAGCTTGTTACTGAACTTCGAATGACAAGAGCCATTCAGCCTCAGATCAATGCTTTT
  TTACAGGGCTTTCATATGTTCATTCCACCCTCCCTCATACAGCTTTTTGATGAATATGAA
  TTGGAGCTACTGCTTTCTGGCATGCCAGAAATTGATGTGAGTGATTGGATAAAAAATACA
  GAATACACAAGTGGCTATGAAAGAGAAGATCCAGTTATTCAGTGGTTCTGGGAAGTTGTA
  GAAGACATTACTCAAGAGGAGAGAGTTCTTCTCTTACAGTTTGTTACGGGCAGTTCCAGG
  GTCCCACATGGTGGGTTTGCTAATATCATGGGTGGAAGTGGATTGCAAAACTTTACAATC
  GCTGCTGTGCCATATACTCCAAATCTTTTACCAACTTCAAGCACATGCATCAACATGCTC
  AAGTTACCTGAATACCCAAGTAAAGAAATACTCAAGGACAGACTTCTTGTGGCACTACAT
  TGTGGCAGCTATGGTTACACAATGGCATAA
  
  Clone variation with respect to NM_020771.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020771 unedited
  ATACGACTCACTATAGGGGCGGCCGCGATTCGGCACGAGGGGCGGCGGGGGCTGCAGGAA
  AGGCGCGAGCAGAGGCGGCGGCGGGTGTACTGTAGGTGGTCGGTCCGGCAGCAGCCCGGC
  CCCCGGACGCAGGACGTGGCCCCAGGCAGCCCTCGCAGCTCAGTGCTCTAGCCGGGGCAA
  GCCCGCGTCTCCGCCTGCTGGACGGGCCCAGGCGAGATGTAGGGCTCTGGGCGCGGAGGC
  CGCCGGTGGGGCGGCTGATCGCGGAGGATCGCGGAGGGCGCGCCGAGGATGGAGAGAGCG
  ATGGAGCAACTCAACCGCCTGACGCGCTCGCTGCGCCGCGCGCGCACCGTGGAGTTGCCC
  GAGGATAATGAAACTGCTGTTTATACATTAATGCCAATGGTTATGGCTGATCAACACAGG
  TCTGTTTCTGAACTACTATCAAATTCAAAATTTGATGTCAATTATGCATTCGGACGTGTG
  AAAAGAAGCTTGCTTCACATTGCAGCAAATTGTGGATCGGTGGAATGCTTGGTTTTGCTG
  TTAAAGAAAGGAGCAAATCCTAACTATCAAGATATTTCAGGCTGTACACCCCTTCATTTG
  GCAGCAAGAAATGGGCAGAAGAAATGTATGAGTAAATTATTAGAATATAGCGCTGATGTC
  AACATTTGTAATAATGAAGGCCTTACAGCAATACATTGGCTGGCTGTGAATGGGCGGACA
  GAACTACTCCATGACCTTGTGCAGCATGTCANTGATGNNTGATGTGAGGATGCCATGGGG
  CAGACAGCACTGCATGTTGCCTGCCAGAACGTCACAGAAGACAGTGCAGTGCTTGCTAGA
  CAGTGGTGCTGATATTACAGGCCAATGTATCAGGGAGCACTCATGTACTTTGCTGCAGTC
  ATGTCAAAAGT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020771
• ORF Size: 2730 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020771.2, NP_065822.1
• RefSeq Size: 4614
• RefSeq ORF: 2730
• Locus ID: 57531
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016]
  Transcript Variant: This variant (1) encodes the longest isoform (a).