TIFA (NM_052864) Human Untagged Clone

CAT#: SC107567

TIFA (untagged)-Human TRAF-interacting protein with forkhead-associated domain (TIFA)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TIFA
• Synonyms: T2BP; T6BP; TIFAA
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC107567 sequence for NM_052864 edited (data generated by NextGen Sequencing)
  ATGACCAGTTTTGAAGATGCTGACACAGAAGAGACAGTAACTTGTCTCCAGATGACGGTT
  TACCATCCTGGCCAGTTGCAGTGTGGAATATTTCAGTCAATAAGTTTTAACAGAGAGAAA
  CTCCCTTCCAGCGAAGTGGTGAAATTTGGCCGAAATTCCAACATCTGTCATTATACTTTT
  CAGGACAAACAGGTTTCCCGAGTTCAGTTTTCTCTGCAGCTGTTTAAAAAATTCAACAGC
  TCAGTTCTCTCCTTTGAAATAAAAAATATGAGTAAAAAGACCAATCTGATCGTGGACAGC
  AGAGAGCTGGGCTACCTAAATAAAATGGACCTGCCATACAGGTGCATGGTCAGATTCGGA
  GAGTATCAGTTTCTGATGGAGAAGGAAGATGGCGAGTCATTGGAATTTTTTGAGACTCAA
  TTTATTTTATCTCCAAGATCACTCTTGCAAGAAAACAACTGGCCACCACACAGGCCCATA
  CCGGAGTATGGCACTTACTCGCTCTGCTCCTCCCAAAGCAGTTCTCCGACAGAAATGGAT
  GAAAATGAGTCATGA
  
  Clone variation with respect to NM_052864.2
  498 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_052864 unedited
  CCGGGCCCCCCNNNNNCCCCCCCCCCCGGTTCAGATTTGTATACGACTCCTATAGGCGGC
  CGCGNAATTCGCACCAGGGAAGCAGGCCGCGCGCGCGGGAGCGCGGGAGGATCGGCGGCT
  CGCGGTCACTGGTCCCTGGCTCGGTTCCCCGCACCCCGGGGCTCACACTTACCCGCGCGG
  AGGAGCAGCGGCCGGGTGTCCACCCCCATCCTGCGCCCAGTCTCCTCGATTCCCCTCGCT
  CTGAGCCGGGAGAGCCGAACAGCTGAAGAGAGTTCACTGACTCCCCAGCCCCAGGTGGGC
  CTTGTGCACATCATGACCAGTTTTGAAGATGCTGACACAGAAGAGACAGTAACTTGTCTC
  CAGATGACGGTTTACCATCCTGGCCAGTTGCAGTGTGGAATATTTCAGTCAATAAGTTTT
  AACAGAGAGAAACTCCCTTCCAGCGAAGTGGTGAAATTTGGCCGAAATTCCAACATCTGT
  CATTATACTTTTCAGGACAAACAGGNTTCCCGAGTTCAGTTNTCTCTGCAGCTGTTTAAA
  AATTCAACAGCTCAGTTCTCTCCTTTGAANTANAAATATGAGTAANAAGACAATCTGATC
  GTGGACAGCANAGAGCTGGGCTACCTAAATAAAATGGACCTGCCATACAGGTGCATGGNT
  CAGATCGGAGAGTATCAGTTTCTGATGGAGAAGGAGATGGCGAGTCATTGGAATTTTTTG
  AGACTCCATTTATTTTATCTCCCAGATCACTCTTGCAGAAAAACACTGGCCAACACACAG
  GCCCATACCGGAGTTGGCACTTACTCGGTTTGCTCTCCCAAGCAGTTCTCCGAACGAAAT
  GGATGAAATGAGTCCTGAACCCGAAAGTCTANAAGGAAAATTTGATGGATGAAAAGCTTT
  GTAATGCTGATAGCACCTAAAATAGAGTGATAGGGGAGNATATTATAGCCATCTGTATGC
  TGTGAAATTGGAATNCAAATTTGNAGCCTGAAAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_052864
• ORF Size: 555 bp
• Insert Size: 1750
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_052864.2, NP_443096.1
• RefSeq Size: 3090
• RefSeq ORF: 555
• Locus ID: 92610
• Gene Summary: This gene encodes an adapter protein involved in adaptive and innate immunity. This protein includes a forkhead-associated (FHA) domain that specifically binds to phosphorylated serine and threonine residues. In response to bacterial infection, the encoded host cell protein undergoes an intermolecular interaction between the FHA domain and a phosphorylated threonine that leads to protein oligomerization and stimulation of the NF-kappa B and other downstream signaling pathways. This protein exhibits reduced expression in hepatocellular carcinoma and may suppress hepatocellular carcinoma progression. This protein may also play a role in the DNA damage response. [provided by RefSeq, Jun 2018]