MNK1 (MKNK1) (AB000409) Human Untagged Clone

CAT#: SC107659

(untagged)-Human mRNA for MNK1, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MKNK1
• Synonyms: MNK1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for AB000409 edited
  ATGGTATCTTCTCAAAAGTTGGAAAAACCTATAGAGATGGGCAGTAGCGAACCCCTTCCC
  ATCGCAGATGGTGACAGGAGGAGGAAGAAGAAGCGGAGGGGCCGGGCCACTGACTCCTTG
  CCAGGAAAGTTTGAAGATATGTACAAGCTGACCTCTGAATTGCTTGGAGAGGGAGCCTAT
  GCCAAAGTTCAAGGTGCCGTGAGCCTACAGAATGGCAAAGAGTATGCCGTCAAAATCATC
  GAGAAACAAGCAGGGCACAGTCGGAGTAGGGTGTTTCGAGAGGTGGAGACGCTGTATCAG
  TGTCAGGGAAACAAGAACATTTTGGAGCTGATTGAGTTCTTTGAAGATGACACAAGGTTT
  TACTTGGTCTTTGAGAAATTGCAAGGAGGTTCCATCTTAGCCCACATCCAGAAGCAAAAG
  CACTTCAATGAGCGAGAAGCCAGCCGAGTGGTGCGGGACGTTGCTGCTGCCCTTGACTTC
  CTGCATACCAAAGGCATTGCTCATCGTGATCTGAAACCAGAAAATATATTGTGTGAATCT
  CCAGAAAAGGTGTCTCCAGTGAAAATCTGTGACTTTGACTTGGGCAGTGGGATGAAACTG
  AACAACTCCTGTACCCCCATAACCACACCAGAGCTGACCACCCCATGTGGCTCTGCAGAA
  TACATGGCCCCTGAGGTAGTGGAGGTCTTCACGGACCAGGCCACATTCTACGACAAGCGC
  TGTGACCTGTGGAGCCTGGGCGTGGTCCTCTACATCATGCTGAGTGGCTACCCACCCTTC
  GTGGGTCACTGCGGGGCCGACTGTGGCTGGGACCGGGGCGAGGTCTGCAGGGTGTGCCAG
  AACAAGCTGTTTGAAAGCATCCAGGAAGGCAAGTATGAGTTTCCTGACAAGGACTGGGCA
  CACATCTCCAGTGAAGCCAAAGACCTCATCTCCAAGCTCCTGGTGCGAGATGCAAAGCAG
  AGACTTAGCGCCGCCCAAGTTCTGCAGCACCCATGGGTGCAGGGGCAAGCTCCAGAAAAG
  GGACTCCCCACGCCGCAAGTCCTCCAGAGGAACAGCAGCACAATGGACCTGACGCTCTTC
  GCAGCTGAGGCCATCGCCCTTAACCGCCAGCTATCTCAGCACGAAGAGAACGAACTAGCA
  GAGGAGCCAGAGGCACTAGCTGATGGCCTCTGCTCCATGAAGCTTTCCCCTCCCTGCAAG
  TCACGCCTGGCCCGGAGACGGGCCCTGGCCCAGGCAGGCCGTGGTGAAGACAGGAGCCCG
  CCCACAGCACTCTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AB000409 unedited
  CGTGCAGNATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCCGCGTTC
  TCGGAGGAGCGATCTGCAGGTTTCCATGTCAGAGGCCGATGGAGAACTGAAGATTGCCAC
  CTACGCACAAAGGCCATTGAGACACTTCGTGTAGCTGGAAGACACCAACTTCCTGACAGG
  AGCTTTATTTCATTTGGGATTTCAAGTTTACAGATGGTATCTTCTCAAAAGTTGGAAAAA
  CCTATAGAGATGGGCAGTAGCGAACCCCTTCCCATCGCAGATGGTGACAGGAGGAGGAAG
  AAGAAGCGGAGGGGCCGGGCCACTGACTCCTTGCCAGGAAAGTTTGAAGATATGTACAAG
  CTGACCTCTGAATTGCTTGGAGAGGGAGCCTATGCCAAAGTTCAAGGTGCCGTGAGCCTA
  CAGAATGGCAAAGAGTATGCCGTCAAAATCATCGAGAAACAAGCAGGGCACAGTCGGAGT
  AGGGTGTTTCGAGAGGTGGAGACGCTGTATCAGTGTCAGGGAAACAAGAACATTTTGGAG
  CTGATTGAGTTCTTTGAAGATGACACAAGGTTTTACTTGGTCTTTGAGAAATTGCAAGGA
  GGTTCCATCTTAGCCCACATCCAGAAGCAAAAGCACTTCAATGAGCGAGAAGCCAGCCGA
  GTGGTGCGGGACGTTGCTGCTGCCCTTGACTTCCTGCATACCAAAGGCATTGCTCATCGT
  GATCTGAAACCAGAAAATATATTGTGTGAATCTNCAGAAAAGGTGTCTCCAGTGAAAATC
  TGTGACTTTGACTTGNGCAGTGGGATGAAACTGAACAACTCCTGTACCCCCATAACCACA
  CCAGAGCTGACCACCCCATGTGGCTCTGCAGATACATGGCNNCCTGAGTAGTGGAGGGTC
  TCACGGACCANGCCACATT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for AB000409 unedited
  GCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTAGAATTTCAGTTTTATTAAAAT
  AAGCACAATGTATAAAAGCACCGTGGTGTTGTATAAACGTCTGCCTGACAAATGCAAATC
  TATTTTCTTTATGTAACTCAATAGTTCCACTTATCTGAATGGCTGTACCTTCATGCACAC
  GGGCAGCAGGCACTGCATTGCTCAAACAGGGAAGTGAGGCTTCACCCTAGTGTGGCTTCA
  CCTTAGGCACAGAGCACTATCTAACTGCCCAGATCTGTGCCACCCACACAAGACCTGGGG
  ACACAGCAGCAGACACCGATGCTGTCTCTAAGTTCATCACAGGAACAGCTTAAAATCAGA
  ATAATAGGGAACTGCTGATTAAAACCCAAGTGCATGGACATTCTAGAAAGAAGAGCAAGC
  CGTTCCACTCTCTGGGAAGTTCATGGGCTTGCAGTGGGAGTTTAAGGTATCATCTTTGCT
  GGAACAGCATGGTTAAAAACACCAAACTTTTTTTTTAAAAAAACGATACTACTGACTTTA
  GCAGCAATCACAAACAAAGGGGATGATAAACGAGGGATACATTTCAGTCACAGCAAAGAA
  AGATTATGTGCTTTTCCGTGCTGCAAACCGGAAGACTGATTTGATTCCCTGAATGACGAA
  CGCTCCCTGCCCCTTCCTGATTGAGGGGATGGCTCTGCTCACCCCAAGGAGAATACGGCC
  AAAAAGACATCCCGAGGACAAAAGAAGGTGGTAAGACCCCCATAGGAGGGGACCCAAAAT
  AGAGGGACGAGCCCCTGTCGGCAACCTTTGAAACTGAGGCTTTTGCCTTTCCCTGAAGGT
  GGAACCCCCAACCCCCCAACTACCACGGTGAAGAGAAGCTTGTATCCACAATCTTGGAGG
  GGGTGAACAGGGCGAGACCCACAGAAAAAAATTTCTTCGTCCACCGCAATCATCCCAAGA
  GAATAGGATGGCTTTCCCTTTCAAAAAAACCACTTCGAGAAAG
  
• Restriction Sites: NotI-NotI
• ACCN: AB000409
• ORF Size: 1275 bp
• Insert Size: 2740
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: AB000409.1, BAA19885.1
• RefSeq Size: 2617
• RefSeq ORF: 1275
• Locus ID: 8569
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Insulin signaling pathway, MAPK signaling pathway
• Gene Summary: This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012]