FBXO44 (NM_183413) Human Untagged Clone

CAT#: SC107685

FBXO44 (untagged)-Human F-box protein 44 (FBXO44), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBXO44
• Synonyms: FBG3; FBX6A; FBX30; Fbx44; Fbxo6a
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC107685 sequence for NM_183413 edited (data generated by NextGen Sequencing)
  ATGGCTGTGGGGAACATCAACGAGCTGCCCGAGAACATCCTGCTGGAGCTGTTCACGCAC
  GTGCCCGCCCGCCAGCTGCTGCTGAACTGCCGCCTGGTCTGCAGCCTCTGGCGGGACCTC
  ATCGACCTCGTGACCCTCTGGAAACGCAAGTGCCTGCGAGAGGGCTTCATCACTGAGGAC
  TGGGACCAGCCCGTGGCCGACTGGAAGATCTTCTACTTCTTACGGAGCCTGCACAGGAAC
  CTCCTGCACAACCCGTGCGCTGAAGAGGGGTTCGAGTTCTGGAGCCTGGATGTGAATGGA
  GGCGATGAGTGGAAGGTGGAGGATCTCTCTCGAGACCAGAGGAAGGAATTCCCCAATGAC
  CAGGTTCGCAGCCAGGCCAGATTGCGGGTCCAAGTACCAGCTGTGCGTTCAGCTCCTGTC
  GTCCGCGCACGCGCCTCTGGGGACCTTCCAGCCAGACCCGGCGACCATCCAGCAGAAGAG
  CGATGCCAAGTGGAGGGAGGTCTCCCACACATTCTCCAACTACCCGCCCGGCGTCCGCTA
  CATCTGGTTTCAGCACGGCGGCGTGGACACTCATTACTGGGCCGGCTGGTACGGCCCGAG
  GGTCACCAACAGCAGCATCACCATCGGGCCCCCGCTGCCCTGACACCCCCTGAGCCCCCA
  TCTGCTGAACCCTGA
  
  Clone variation with respect to NM_183413.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_183413 unedited
  NGGGCAATATTTGTATACGACTCATATAGGGCGGCCGCGATTCGGCACGAGGCTTGGGCG
  GCCCAGCGGATCGTGCCGCGGCGGCCGAGCGCAGCTACAGGAGGGTGTCCAGAAGCCACA
  AGCCATGGCTGTGGGGAACATCAACGAGCTGCCCGAGAACATCCTGCTGGAGCTGTTCAC
  GCACGTGCCCGCCCGCCAGCTGCTGCTGAACTGCCGCCTGGTCTGCAGCCTCTGGCGGGA
  CCTCATCGACCTCGTGACCCTCTGGAAACGCAAGTGCCTGCGAGAGGGCTTCATCACTGA
  GGACTGGGACCAGCCCGTGGCCGACTGGAAGATCTTCTACTTCTTACGGAGCCTGCACAG
  GAACCTCCTGCACAACCCGTGCGCTGAAGAGGGGTTCGAGTTCTGGAGCCTGGATGTGAA
  TGGAGGCGATGAGTGGAAGGTGGAGGATCTCTCTCGAGACCAGAGGAAGGAATTCCCCAA
  TGACCAGGTTCGCAGCCAGGCCAGATTGCGGGTCCAAGTACCAGCTGTGCGTTCAGCTCC
  TGTCGTCCGCGCACGCGCCTCTGGGGACCTTCCAGCCAGACCCGGCGACCATCCAGCAGA
  AGAGCGATGCCAAGTGGAGGGAGGTCTCCCACACATTCTCCAACTACCCGCCCGGCGTCC
  GCTACATCTGGTTTCAGCACGGCGGCGTGGACACTCATTACTGGGCCGGCTGGTACGGCC
  CCGAGGTCACCAACAGCAGCATCACCATCGGGCCCCCGCTGCCCTGACACCCCCTGAGCC
  CCCATCTGCTGAACCCTGACTGGTAAACAACTGCTGTCANAAAAGGGCTGNNGCTTGNGA
  AGGGGNAGGTGGAGGCCAGGTGTCCCCAGAACTCTAACCCTGCCCCTACAGCCTCTTCTT
  GTGGAGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_183413 unedited
  CCTTTTTTTGGCTGCATGCAGTAGGGGCGAATCAGGAGAACACTGCTATCTTTCCAGCAG
  GACAAGAGGCAAGTTCCAGGGTGGTTGGCTGGGAGACAGAGGTCTTGGGAATGGCAGTTC
  TAGGGGTGGGGTGGGGGCTTGGAATGCTCTCCAAGCCAGAGGGGGCCGGGCCTGGATTTG
  GGAGGTGGACAGGGGATTCTTCAAACCCCCTACCATACTCATCCAGGGCTCATGTGTCCA
  GCTGTCAGAGCAGGTCCCAATCCTGCTCCCCATCTACCCTGGGACATCCTGTACAGGATT
  CCCTCAGTCCTCTGGGAACCTAACCCCACCTGGTACCCATCTAGCTTCTGGGGCTCCACT
  GACAGTGAGGACAGTCCACACCCGACCTGGACCCCACCCCACCCTGGGTCTGTCCATCTC
  AGTCCCGGCCTGAGCCTCTGGGCCAAAGCCACCTCTTCTGAGCAGGCAGGCAGAGCGAGA
  GACTGGGAGCAGCAGACAGGGGCAGAGCACGGCCCATGAGCCCACCCTCCACTTCCCAGA
  TTGGTCAGAGTTACATGGTCACCTCCCTGCACCTGCACCATCAGGGCAGCTGCAAGCTTG
  CCAGTTGTCTTGCCTGTCCCTGCTCCGAGGGTCAAAGAACACAGGTAGAATGGTCCCAGG
  AGGGGAAGGGAGAGACAGATCCAGGCTGGCCTCCAAGCTCGACTTTCTGAGGGGCCCAGG
  GGAACATGCTGCACCTNCCACATCTCANGTGCTCCGTCTCTGAAGGGGCACACGCAGGCT
  TTCCNCGCCATCATTCANGTCAAGACCTTTCGGGGAGAGCTGCCCCGCCCCAGCATGCGA
  GGGCTGCCCACACTGANAGGGCTCCACAAGAAAAGCTGCTAGGGGCAAGGNNTANNNAGT
  CTGGGACACCTGNNCTNCACTNCCTTNCCAGNCCAGCCTTNTNTGCAGCANTGTTTACAN
  TCAGGGTCANCNATGGGGCTCANGGNTGTCAGGGCACGGGGCCCTATG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_183413
• ORF Size: 675 bp
• Insert Size: 1950
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_183413.2, NP_904320.1
• RefSeq Size: 2823
• RefSeq ORF: 675
• Locus ID: 93611
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Several alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Feb 2015]
  Transcript Variant: This variant (3) uses an alternate splice junction at the 3' end of an internal exon and lacks an alternate internal exon compared to variant 1, that causes a frameshift. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Variants 2, 3, and 5 all encode the same isoform (2).