RNF34 (NM_194271) Human Untagged Clone

CAT#: SC107733

RNF34 (untagged)-Human ring finger protein 34 (RNF34), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RNF34
• Synonyms: CARP-1; CARP1; hRFI; RFI; RIF; RIFF
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC107733 sequence for NM_194271 edited (data generated by NextGen Sequencing)
  ATGAGGAAGGCGGGTGCCACGTCTATGTGGGCTTCGTGCTGTGGGCTGCTGAATGAAGTC
  ATGGGAACTGGAGCTGTCAGGGGCCAGCAGTCAGCATTTGCAGGAGCCACCGGTCCATTC
  AGATTTACACCAAACCCTGAGTTTTCCACCTACCCACCAGCAGCTACGGAAGGGCCCAAC
  ATAGTTTGTAAAGCCTGTGGGCTTTCATTTTCAGTCTTTAGAAAGAAGCATGTTTGCTGT
  GACTGCAAGAAGGATTTTTGCTCCGTTTGTTCAGTCTTACAAGAAAATCTCCGTAGATGT
  TCTACTTGTCACTTATTACAAGAGACAGCATTTCAGCGCCCTCAGTTAATGCGACTGAAG
  GTGAAGGACCTGCGGCAGTATCTCATTCTGAGAAATATACCCATAGATACTTGTCGTGAG
  AAAGAAGACTTGGTGGATCTAGTACTGTGCCATCATGGACTAGGCTCTGAGGACGACATG
  GACACAAGCAGTCTGAATTCTTCAAGGTCCCAGACTTCTAGCTTTTTTACACGTTCGTTT
  TTTTCAAACTATACAGCCCCCTCTGCTACTATGTCTTCGTTTCAGGGAGAGCTTATGGAT
  GGAGACCAAACATCCAGATCTGGAGTGCCGGCACAGGTACAAAGTGAAATCACTTCAGCA
  AACACAGAAGATGATGATGACGACGATGATGAGGATGATGATGATGAAGAAGAAAACGCA
  GAGGATCGGAACCCCGGGCTCTCCAAGGAGAGAGTGAGAGCTTCACTGTCTGACTTGTCA
  AGCCTTGATGATGTGGAAGGAATGAGCGTGCGCCAGCTGAAGGAAATTCTGGCTCGGAAT
  TTTGTCAACTATTCTGGCTGTTGTGAAAAATGGGAACTGGTAGAGAAAGTAAACCGGTTA
  TACAAAGAGAATGAAGAAAACCAAAAGTCCTATGGCGAGCGGCTGCAGCTGCAGGATGAG
  GAAGACGACAGCCTGTGTCGCATCTGCATGGATGCCGTCATCGACTGTGTCCTACTGGAG
  TGTGGGCACATGGTTACCTGCACCAAGTGCGGCAAGCGCATGAGTGAGTGTCCCATCTGC
  CGGCAGTATGTGGTGCGAGCCGTGCACGTGTTCAAGTCCTGA
  
  Clone variation with respect to NM_194271.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_194271 unedited
  TCAGTATTTTGTAATACGACTCACTCATAGGGCGGCCGCGAATTCGCACGAGTATAAAAC
  AAAAACCCAAGCATGAGGAAGGCGGGTGCCACGTCTATGTGGGCTTCGTGCTGTGGGCTG
  CTGAATGAAGTCATGGGAACTGGAGCTGTCAGGGGCCAGCAGTCAGCATTTGCAGGATCC
  ACCGGTCCATTCATATTTACACCAAACCCTGAGTTTTCCACCTACCCACCATCAGCTACG
  GAAGGGCCCAACATAGTTTGTAAAGCCTGTGGGCTTTCATTTTCAGTCTTTATAAAGAAG
  CATGTTTGCTGTGACTGCAAGAAGGATTTTTGCTCCGTTTGTTCAGTCTTACAAGAAAAT
  CTCCGTAGATGTTCTACTTGTCACTTATTACAAGATACAGCATTTCAGCGCCCTCAGTTA
  ATGCGACTGAAGGTGAAGGACCTGCGGCAGTATCTCATTCTGAGAAATATACCCATAGAT
  ACTTGTCGTGAGAAAGAAGACTTGGTGGATCTAGTACTGTGCCATCATGGACTATGCTCT
  GAGGACGACATGGACACAAGCAGTCTGAATTCTTCAAGGTCCCAGACTTCTAGCTTTTGT
  ACACGTTCGTTGTTTTCAAACTATACAGCCCCCTCTGCTACTATGTCTTCGTTTCAGGGA
  GAGCTTATGGATGGAGACCAAACATCCAGATCTGGAGTGCCGGCACATGTACAAAGTGAA
  ATCACTTCAGCAACACAGAAAATGATGATGACGACGATGATGAGGATGATGATGATGAAG
  AAGATACGCANAGGATCGGAACCNCGGNNNCTCTCAGAGAGAGTGAGAGCTCACTGTCTG
  ACTTGTCAGCCTTGATATGTGGATGAATGANCGTGCGCANCTGAAGAANTNCTGCTCGNN
  ATTTGTCACTTTCTGGCTGTGTGAAAATGGAACTGGTNAGAATGTAACCGGTATCAAGAG
  ATGAGAAAACAAAGTCCTGGCGAGCGCTGCACTGCAGATGAGAAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_194271 unedited
  NAAAACTTAGGAACCGCGGCCGCAANCTAANGATCGGTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTGCCTTTAAAACCAATTTTATTCCCAAAGTTAAA
  AACAGCTAGCGGGTAACACTGAAAATACCCCTTCCCTATACAAAACAATGTAAACTGGTT
  ACCCCTTAATAAGGAATTTAACCCACCCCCTTTTAATAAAAAAAACCAAATGCCCCCCTT
  GGTATAAAAAGCCATACCTGAACAAAAATGGGCATGTGGAGTCCAAAGCCCTGGCAGTCC
  ACTAAAAAAAGGCAGTTGTTCCCAATTATGTTTAAATGCCAAAACCGCCACCATGGGGAA
  ACTTACCTTCCTCAAATGTTAGCCTTTAAAATATACCTGACTAAAAAAGGGAACATTCCA
  AGGAACCCCTGGTCAACATGTTCCATGTCGGCCACTTGTGGACCCTGGTTTCATCCCAAA
  AGGACAAAAGTTTCAAACATCTGAACCGTTTAAGTTAAAAATAGGATGAAGGGGAAATAA
  AAAAACAGGATAAGTGTCCCCCCCAAAAAGCAGTGGCTGATGCCCACATGGGGCAAACAG
  GCTGACTTCAATGAGTGTTCACGGGATGTGTGATAAAACCCAACTGAACCCCGGAAGCTC
  ACGTGTCCACCAGCCAACAGGGCTCACGGCATGGACCAATGTTTCCACAACTCAGGAGGA
  TTCTTTCTGGCCCCCTTAAGAGTCAAAAAAAGGTTTAAAAAACTTCAGCCTTTGAACAAA
  ATTTTCCCGGCCCTTCTGGCATTGAAAGGTTGGGGGCCCAAATTTGGGGGGGACTGCCCG
  GGTGAGGGGAACCCGGTTTTAAGAATTAAAACGTGCCACGGTCGGACCCAATATGCCGGC
  GGAGGGGGCCCTCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_194271
• ORF Size: 1122 bp
• Insert Size: 2100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_194271.1, NP_919247.1
• RefSeq Size: 2105
• RefSeq ORF: 1122
• Locus ID: 80196
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).