Dectin 1 (CLEC7A) (NM_197954) Human Untagged Clone

CAT#: SC107747

CLEC7A (untagged)-Human C-type lectin domain family 7, member A (CLEC7A), transcript variant 6

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CLEC7A
• Synonyms: BGR; CANDF4; CD369; CLECSF12; DECTIN1; SCARE2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC107747 sequence for NM_197954 edited (data generated by NextGen Sequencing)
  ATGGAATATCATCCTGATTTAGAAAATTTGGATGAAGATGGATATACTCAATTACACTTC
  GACTCTCAAAGCAATACCAGGATAGCTGTTGTTTCAGAGAAAGGATCGTGTGCTGCATCT
  CCTCCTTGGCGCCTCATTGCTGTAATTTTGGGAATCCTATGCTTGGTAATACTGGTGATA
  GCTGTGGTCCTGGGTACCATGGCTGGTTTCAAAGCTGTGGAATTCAAAGGATAA
  
  Clone variation with respect to NM_197954.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_197954 unedited
  NNNNNNCCTTCTTACCCCCGCCCGTTGCCTCAAAGGGCGGTAGGCGTGTACGGTGGGNAG
  GTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATA
  GGGCGGCCGCGAATTCGGCACGAGCAGGAGCAGAAAGAAAAGAGCTCCCAAATGCTATAT
  CTATTCAGGGGCTCTCAAGAACAATGGAATATCATCCTGATTTAGAAAATTTGGATGAAG
  ATGGATATACTCAATTACACTTCGACTCTCAAAGCAATACCAGGATAGCTGTTGTTTCAG
  AGAAAGGATCGTGTGCTGCATCTCCTCCTTGGCGCCTCATTGCTGTAATTTTGGGAATCC
  TATGCTTGGTAATACTGGTGATAGCTGTGGTCCTGGGTACCATGGCTGGTTTCAAAGCTG
  TGGAATTCAAAGGATAAATTAATGAAGAAAACAAGCGGAGCTGAAGAAGAAAGTACAATA
  TGGTGCTGTCTTCCTAATGAAATAAATTCACTAAATGGACCAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATC
  CCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTGCCACTC
  CAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCATTTTGTCTGACTAGGTGT
  CCTTCTTAATATATGGGGTGGAGGGGGGGGGNNTTNNNAACCAAGGGGCAAGTGGGGGAA
  GACAACCTGTAGGGCCTGCGGGGTCTATTGGGAACCAAGCTGGAGTGCAGTGGCACAATC
  TTGGCTCACTGCAATCTCCGCCTCCTGGGTTCAGCAATTCTCCGCCTCAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_197954
• ORF Size: 234 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_197954.1, NP_922945.1
• RefSeq Size: 511
• RefSeq ORF: 234
• Locus ID: 64581
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (6) has multiple differences in the coding region, compared to variant 1, one of which results in an early stop codon. The resulting protein (isoform f) has a distinct C-terminus and is much shorter than isoform a.