PTPH1 (PTPN3) (NM_002829) Human Untagged Clone

CAT#: SC107908

PTPN3 (untagged)-Human protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPN3
• Synonyms: PTP-H1; PTPH1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_002829 edited
  CGGCCGCGAATTCGGCACGAGCCAGGTCGCGCCGCGAGCGAGCTTCCGCGCCGCCCGCAC
  GCGCGACCTACCTGGCGCTCCGCGCCCCCGGATGCTGCAGGTTATTCAGCGATAGTTATG
  ACCTCCCGGTTACGTGCGTTGGGTGGAAGAATTAATAATATACGCACCTCGGAGTTACCC
  AAAGAGAAAACTCGATCAGAAGTCATTTGCAGCATCCACTTTTTAGATGGCGTGGTACAG
  ACCTTTAAAGTTACTAAACAAGACACTGGCCAGGTTCTTCTGGATATGGTGCACAACCAC
  CTGGGTGTGACTGAAAAGGAATATTTTGGTTTACAGCATGATGACGACTCCGTGGACTCT
  CCTAGATGGCTGGAAGCAAGCAAACCCATCAGGAAGCAGTTAAAAGGAGGTTTCCCCTGT
  ACCCTGCATTTTCGAGTAAGATTTTTTATACCTGATCCCAACACACTGCAGCAAGAACAA
  ACCAGGCACTTGTATTTCTTACAACTGAAGATGGATATTTGCGAAGGAAGGTTAACCTGC
  CCTCTTAACTCAGCAGTGGTTCTAGCGTCCTATGCCGTACAATCTCATTTTGGAGACTAT
  AATTCTTCCATACATCATCCAGGCTATCTTTCCGATAGTCACTTTATACCCGATCAAAAT
  GAGGACTTTTTAACAAAAGTCGAATCTCTGCATGAGCAGCACAGTGGGCTAAAACAATCA
  GAAGCAGAATCCTGCTATATCAACATAGCGCGGACCCTCGACTTCTATGGAGTAGAACTG
  CACAGTGGTAGGGATCTGCACAATTTAGACCTAATGATTGGAATTGCTTCCGCGGGTGTT
  GCTGTGTACCGAAAATACATTTGCACAAGTTTCTATCCTTGGGTGAACATTCTCAAAATT
  TCTTTCAAAAGGAAAAAGTTCTTCATACATCAGCGACAGAAACAGGCTGAATCCAGGGAA
  CATATTGTGGCCTTCAACATGCTGAATTACCGATCTTGCAAAAACTTGTGGAAATCCTGT
  GTTGAGCACCATACGTTCTTTCAGGCAAAGAAGCTACTACCTCAGGAAAAGAATGTTCTG
  TCTCAGTACTGGACTATGGGCTCTCGGAACACCAAAAAGTCGGTAAATAACCAATATTGC
  AAAAAGGTGATTGGCGGGATGGTGTGGAACCCAGCCATGCGGAGATCCTTATCAGTGGAG
  CACTTAGAAACCAAGAGTCTGCCTTCTCGTTCCCCTCCCATTACTCCCAACTGGCGAAGT
  CCTCGGCTCCGGCACGAAATCCGAAAGCCACGCCACTCTTCTGCAGATAACCTTGCAAAT
  GAAATGACCTACATCACGGAAACGGAAGATGTATTTTACACGTACAAGGGCTCTCTGGCC
  CCTCAAGACAGCGATTCTGAAGTTTCTCAGAACCGAAGCCCGCACCAAGAGAGTTTATCC
  GAGAACAATCCGGCACAAAGCTACCTGACCCAGAAGTCATCCAGTTCTGTGTCTCCATCT
  TCAAATGCTCCAGGCTCCTGCTCACCTGACGGCGTTGATCAGCAGCTCTTAGATGACTTC
  CACAGGGTGACCAAAGGGGGCTCCACCGAGGACGCCAGCCAGTACTACTGTGACAAGAAT
  GATAATGGTGACAGCTACTTAGTCTTGATCCGTATCACACCAGATGAAGATGGAAAATTT
  GGATTTAATCTTAAGGGAGGAGTGGATCAAAAGATGCCTCTTGTGGTATCAAGGATAAAC
  CCAGAGTCACCTGCGGACACCTGCATTCCTAAGCTGAACGAAGGGGATCAAATCGTGTTA
  ATCAATGGCCGGGACATCTCAGAACACACGCATGACCAAGTGGTGATGTTCATCAAAGCC
  AGCCGGGAGTCCCACTCACGGGAGCTGGCCCTGGTGATCAGGAGGAGAGCTGTCCGCTCA
  TTTGCTGACTTCAAGTCTGAAGATGAACTGAACCAGCTTTTCCCCGAAGCCATTTTCCCC
  ATGTGTCCGGAGGGTGGGGACACTTTGGAGGGATCCATGGCACAGCTAAAGAAGGGCCTC
  GAAAGCGGGACGGTGCTGATCCAGTTTGAGCAACTCTACAGAAAAAAGCCAGGTTTGGCC
  ATCACGTTTGCAAAGCTGCCTCAAAATTTGGACAAAAACCGATATAAAGATGTGCTGCCT
  TATGACACCACCCGGGTATTATTGCAGGGAAATGAAGATTATATTAATGCAAGTTACGTG
  AACATGGAAATTCCTGCTGCTAACCTTGTGAACAAGTACATCGCCACTCAGGGGCCCCTG
  CCGCATACCTGTGCACAGTTTTGGCAGGTTGTCTGGGATCAGAAGTTGTCACTCATTGTC
  ATGTTGACGACTCTCACAGAACGAGGGCGGACCAAATGTCACCAGTACTGGCCAGATCCC
  CCCGACGTCATGAACCACGGCGGCTTTCACATCCAGTGTCAGTCAGAGGACTGCACCATC
  GCCTATGTGTCCCGAGAAATGCTGGTCACAAACACCCAGACCGGGGAAGAACACACAGTG
  ACACATCTCCAGTACGTCGCATGGCCTGACCACGGTGTGCCCGATGACTCCTCCGACTTT
  CTGGAATTTGTAAACTATGTGAGGTCTCTGAGAGTGGACAGCGAGCCCGTCCTAGTTCAC
  TGCAGTGCTGGAATAGGTCGAACCGGTGTGTTGGTCACTATGGAAACAGCCATGTGCCTA
  ACTGAGAGGAACCTGCCCATTTACCCACTGGATATTGTCCGAAAAATGCGAGACCAGCGC
  GCCATGATGGTGCAGACATCAAGCCAGTACAAGTTTGTGTGTGAAGCGATTCTTCGTGTG
  TATGAAGAAGGTTTAGTCCAAATGCTGGATCCTAGTTAAGACAACTGTGAAAAAGTTCAT
  TCCTCTTTCCCAAGGGCATCCTCCTTGAAAGAGGAGGACAGACCTCTCTGGAAGCAGCAA
  GAGGAACCAGTAGCTGTGGGAAAGGAATGGGCACCTCTGAACCCAGGCACTTTAAACTTC
  TATAGAAAAGATATCGTGTACATAGGAACTGGTGTAGATAAGCATGCAATTATGGCATCA
  TTTAGGCCTGTATTTCTATGGAAAGATACAAAAAGGATCTCAGTTTGGGGCCTGTCCTAA
  TGCCTTCTTCCCTAACATCACCACACACACCCCTGTCGGCATCCTGGAGCAATTGAGACC
  GGACACCCACAGAGCTGTTGTCCTCCCAGCAACAAGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002829 unedited
  NNGGTTCANATTTTGTATACGACTCCTATAGGCGGCNCGCGATTCGGCACGAGCCAGGTC
  GCGCCGCGAGCGAGCTTCCGCGCCGCCCGCACGCGCGACCTACCTGGCGCTCCGCGCCCC
  CGGATGCTGCAGGTTATTCAGCGATAGTTATGACCTCCCGGTTACGTGCGTTGGGTGGAA
  GAATTAATAATATACGCACCTCGGAGTTACCCAAAGAGAAAACTCGATCAGAAGTCATTT
  GCAGCATCCACTTTTTAGATGGCGTGGTACAGACCTTTAAAGTTACTAAACAAGACACTG
  GCCAGGTTCTTCTGGATATGGTGCACAACCACCTGGGTGTGACTGAAAAGGAATATTTTG
  GTTTACAGCATGATGACGACTCCGTGGACTCTCCTAGATGGCTGGAAGCAAGCAAACCCA
  TCAGGAAGCAGTTAAAAGGAGGTTTCCCCTGTACCCTGCATTTTCGAGTAAGATTTTTTA
  TACCTGATCCCAACACACTGCAGCAAGAACAAACCAGGCACTTGTATTTCTTACAACTGA
  AGATGGATATTTGCGAAGGAAGGTTAACCTGCCCTCTTAACTCAGCAGTGGTTCTAGCGT
  CCTATGCCGTACAATCTCATTTTGGAGACTATAATTCTTCCATACATCATCCANGCTATC
  TTTCCGATAGTCACTTTATACCCGATCAAAATGAGGACTTTTTAACCAAAGTCGAATCTC
  TGCATGAGCAGCACAGTGGGCTAAAACATTAGAAGCCGAAATCTGCTTTATCCACATAAC
  GCGGACCCTCGACTTCTATGGAGTANAACTGGCCAATGGTACGGACCCTCCCATCAAACC
  TAAAGCTCGAAATGCTTCCCCGGTGTTCGTTCCNACCCCTATACTTTCCCACAGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002829 unedited
  GGCGACAATTTATCTTCTCTTAAATAATAATTTGCTACACTCCCTGTCACAAATTTAAAA
  AAATTTAACACGGTATTCACAAAGGCAGAATTCTTTAGGACAATCAAAATGATGGTGCTC
  TTACAATAAATTAACATCAGGATTGTGTTCATATTCAGATAGCTCTGATCCTATCCCCTT
  GAAACGCAATGGAGACCATTCCGACTGGGGGTGAATGCACTTATCTGTTCCCTCCTTCTC
  AGACTCCGCCTTCATCTATCCTCCCCGCGCACCTGAATCCCTTTGGACTCCTGGTATAAA
  TTGACCCCTGGGTCCCGCGCCCCGTCCTCCGCCCCCCCGTCCCCCTTTACCCCCCCCTTT
  CCCTCGATGCCCTTTCCTCCTCCTCCCCTCCCCTTTTTCTCGTCCATGACCCACCCGTCC
  TTGCCTCGTGTGCCGCGCTCCTCCGTCCCGCCCGGCGCCGGTCTTCCGCCTTTCTCTTCC
  TCGCCGCTTCCACTTTTCCTCGCTTTTTTTCCCCCCTCTCCGTTGCCCCTCCCCGTTCCC
  CGTTCCCTCTCCCTATCACGTCCCTCCCCTGTTTCCCCCCCCTTTCTGCTTCGGTGTTCC
  TCCCGCCTCCGCATCGGTCGTTTTTCCCCTTTTTCGCTCATTCCGTCTTTCCCCCTTCGC
  CTCGTTTCCCCGTCCCGTGCGTCCCGTGCCGTATTCTTCGTCGCCGCTTCCCGCTCCCGT
  TGCCCGTATTTCGCGTTACGCGCCGGTGTATCCCGTGTTTCCGCCGCTCATCCCCGTGGC
  GCCGCACCTTGTCCAATGCCCGTTCATCGCGCCCCGTGCGCCTATATCGCGCCGTAGTTC
  GCTATCTGCGNTTTCGTCCGCCGTGCGCGCCGCTGTCTCCGTCTCGCGCTCGCCGCTGTT
  TACACGCGCTGTGTTACTCGCGCTGTCTCGCGCTTCGATACGTTTAGTTTCGCCATAAGT
  TCGCCGCGTCGTATNCGCGCTCGCGCGCGCCCNCACTGCGCGTGTTATTGCCGCGTNTTC
  TCGCGCCATTAACTCGCGCGGCCGCACGCTCTCTGTCGTTCGTCGCACGCCTTGTATCTG
  CGTATGTGGTACGGCCGCGTCGTCTGCGCCCGCTATTNTACGCGGCGCCACTACTCTCGC
  TTTNTATTCCGATCGTCGCGCACGCCGTCCCGTCGCACGCNATGCCGCTGCGNACACTCC
  ACGCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002829
• Insert Size: 5000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002829.2, NP_002820.2
• RefSeq Size: 4104 bp
• RefSeq ORF: 2742 bp
• Locus ID: 5774
• Cytogenetics: 9q31.3
• Domains: Y_phosphatase, B41, PDZ, PTPc_motif
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]'
  Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.