SIRT2 (NM_012237) Human Untagged Clone

CAT#: SC107915

SIRT2 (untagged)-Human sirtuin 2 (SIRT2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SIRT2
• Synonyms: SIR2; SIR2L; SIR2L2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC107915 sequence for NM_012237 edited (data generated by NextGen Sequencing)
  ATGGCAGAGCCAGACCCCTCTCACCCTCTGGAGACCCAGGCAGGGAAGGTGCAGGAGGCT
  CAGGACTCAGATTCAGACTCTGAGGGAGGAGCCGCTGGTGGAGAAGCAGACATGGACTTC
  CTGCGGAACTTATTCTCCCAGACGCTCAGCCTGGGCAGCCAGAAGGAGCGTCTGCTGGAC
  GAGCTGACCTTGGAAGGGGTGGCCCGGTACATGCAGAGCGAACGCTGTCGCAGAGTCATC
  TGTTTGGTGGGAGCTGGAATCTCCACATCCGCAGGCATCCCCGACTTTCGCTCTCCATCC
  ACCGGCCTCTATGACAACCTAGAGAAGTACCATCTTCCCTACCCAGAGGCCATCTTTGAG
  ATCAGCTATTTCAAGAAACATCCGGAACCCTTCTTCGCCCTCGCCAAGGAACTCTATCCT
  GGGCAGTTCAAGCCAACCATCTGTCACTACTTCATGCGCCTGCTGAAGGACAAGGGGCTA
  CTCCTGCGCTGCTACACGCAGAACATAGATACCCTGGAGCGAATAGCCGGGCTGGAACAG
  GAGGACTTGGTGGAGGCGCACGGCACCTTCTACACATCACACTGCGTCAGCGCCAGCTGC
  CGGCACGAATACCCGCTAAGCTGGATGAAAGAGAAGATCTTCTCTGAGGTGACGCCCAAG
  TGTGAAGACTGTCAGAGCCTGGTGAAGCCTGATATCGTCTTTTTTGGTGAGAGCCTCCCA
  GCGCGTTTCTTCTCCTGTATGCAGTCAGACTTCCTGAAGGTGGACCTCCTCCTGGTCATG
  GGTACCTCCTTGCAGGTGCAGCCCTTTGCCTCCCTCATCAGCAAGGCACCCCTCTCCACC
  CCTCGCCTGCTCATCAACAAGGAGAAAGCTGGCCAGTCGGACCCTTTCCTGGGGATGATT
  ATGGGCCTCGGAGGAGGCATGGACTTTGACTCCAAGAAGGCCTACAGGGACGTGGCCTGG
  CTGGGTGAATGCGACCAGGGCTGCCTGGCCCTTGCTGAGCTCCTTGGATGGAAGAAGGAG
  CTGGAGGACCTTGTCCGGAGGGAGCACGCCAGCATAGATGCCCAGTCGGGGGCGGGGGTC
  CCCAACCCCAGCACTTCAGCTTCCCCCAAGAAGTCCCCGCCACCTGCCAAGGACGAGGCC
  AGGACAACAGAGAGGGAGAAACCCCAGTGA
  
  Clone variation with respect to NM_012237.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012237 unedited
  GCTTTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGGACACAGTGG
  TTGGTGACGGGACAGAGCGGTCGGTGACAGCCTCAAGGGCTTCAGCACCGCGCCCATGGC
  AGAGCCAGACCCCTCTCACCCTCTGGAGACCCAGGCAGGGAAGGTGCAGGAGGCTCAGGA
  CTCAGATTCAGACTCTGAGGGAGGAGCCGCTGGTGGAGAAGCAGACATGGACTTCCTGCG
  GAACTTATTCTCCCAGACGCTCAGCCTGGGCAGCCAGAAGGAGCGTCTGCTGGACGAGCT
  GACCTTGGAAGGGGTGGCCCGGTACATGCAGAGCGAACGCTGTCGCAGAGTCATCTGTTT
  GGTGGGAGCTGGAATCTCCACATCCGCAGGCATCCCCGACTTTCGCTCTCCATCCACCGG
  CCTCTATGACAACCTAGAGAAGTACCATCTTCCCTACCCAGAGGCCATCTTTGAGATCAG
  CTATTTCAAGAAACATCCGGAACCCTTCTTCGCCCTCGCCAAGGAACTCTATCCTGGGCA
  GTTCAAGCCAACCATCTGTCACTACTTCATGCGCCTGCTGAAGGACAAGGGGCTACTCCT
  GCGCTGCTACACGCAGAACATAGATACCCTGGAGCGAATAGCCGGGCTGGAACAGGAGGA
  CTTGGTGGAGGCGCACGGCACCTTCTACACATCACACTGCGTCAGCGCCAGCTGCCGGCA
  CGAATACCCCGCTAGCTGGATGAAAGNAGAAGATCTCTCTGAGGTGACGCCCAGTGTGAA
  GACTGTCAGAGCCTGGTGAAGCTGATATCGTCTTTTTGGTGAGAGCCTCCAGCGCGTTNC
  TTCTCCTGGATGCAGTCAGACTCCCTGGAGGGGGACCTCTNCTGGNCATGGNTACCTCCC
  TTGCAGGGCAGCCCTTTGCCTCCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012237 unedited
  GCCTTTGAGAGTCGAGTTTTTCCCTTTTTTTTTTAGCTGTTTTTGTTTTTAATTTGTCTC
  CAATAAGCAATGTCTTCTGCCCATCCAGCATGGGAAGTGGGTCCCACGTGAAGGGGGCCC
  ACCACCCACTTTGGGAGCTGAAGGCAGAGACTCGGGAGCCCTCCCGGCTCAGACTCCCCC
  TACGCTGGGTGTGGGTTATATTCATAGGCCCACACCCACACTGGGGTAGGCTAGGTATGG
  TTTACTTAGCCACAGGCCCCCGGGGGCAGGAGACAGAGTGGGGGCCCGAAGCTCCCTGTC
  CTGGAAGAGTTAAAAGTTCTGGGGTAGCCCTGGCCCCGTGGGGGCAGTTAGAGATGAGGG
  AGGTTACTCCTTAGCCCAGGAGTGGTTAGAGACAGCGGGGCTGGTAGAGATGCCTGTTTA
  AGCCTTGGCCTCTAGGAGGTGCCAGAGATTTGCTGGGGTTGGGGGCCAGGGTTGCTGGGA
  CCCCAGTTTTGGGGAGGGAGCTGTAAGAGATTGGGGGATGTTCTGAGCTCCCCAGACAAG
  AACTGCTGGTTAAGAGGGGGCCAGGCCCGGTTGGCGCTCAGCTGTCCCTGAGGAGCTCGA
  TATACCGCCTGGGAGATGCAGCTGCCACTGCCGTCTCCTACCTCTCTGTTGAACTGCCCT
  TCGACCTGGCAGGCGGCCGGGACTCTCTTGGGGGAAGCTGAAGTGCTGGGGTTCGGGGAC
  CTCGCCCCCGAATGGGCCTCTATGCTGGCGGGCTACCCTCGGACCAGGGTCCCGCAGCTA
  CCTTCTCCCTCCAAGCGATTCCACCAGGCCAGGTCCTTCTGGCTTCATTCACCCCTTCGC
  CTCCGCCCCGTAGGCCTCTTTGGGTCCAACCGCTTCTCCCCTTTGGTCCTTATCCTCCTT
  TCAAGGCCTTCCCGCGCCCCTTCCTTTCTCCCCGATCACCCGTTTCCCCAGCCCGCCCCG
  CATCCCCATCTTCGCCTCCCCACGCCCCTCCCTCGCGCCTTCCGCTCCCCCCCCCGTTN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012237
• ORF Size: 1170 bp
• Insert Size: 1850
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012237.2, NP_036369.2
• RefSeq Size: 1963
• RefSeq ORF: 1170
• Locus ID: 22933
• Domains: SIR2
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]
  Transcript Variant: This variant (1) is the longest transcript and encodes the longest isoform (1).