ADH6 (NM_000672) Human Untagged Clone

CAT#: SC107930

ADH6 (untagged)-Human alcohol dehydrogenase 6 (class V) (ADH6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADH6
• Synonyms: ADH-5
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_000672 edited
  ATGAGTACTACAGGCCAAGTCATCAGATGCAAAGCAGCCATACTCTGGAAGCCTGGTGCA
  CCATTTTCTATTGAAGAGGTAGAAGTGGCCCCACCAAAGGCAAAGGAAGTTCGCATAAAG
  GTTGTGGCCACCGGACTGTGTGGTACAGAGATGAAAGTGTTGGGGAGTAAACACTTGGAC
  CTCTTGTATCCCACCATCTTGGGCCATGAAGGGGCTGGAATCGTTGAGAGTATTGGAGAA
  GGAGTAAGCACAGTGAAACCAGGTGACAAAGTTATCACACTCTTTCTGCCACAGTGTGGA
  GAATGTACCTCTTGCCTGAATTCTGAGGGCAATTTTTGTATACAATTCAAACAGTCAAAA
  ACCCAACTGATGTCTGATGGTACCAGCAGGTTTACCTGCAAGGGAAAATCAATATATCAC
  TTTGGTAATACCAGCACCTTCTGTGAATACACAGTGATAAAGGAAATCTCAGTTGCCAAG
  ATTGATGCAGTCGCTCCTCTAGAGAAAGTATGCCTAATTAGCTGTGGCTTTTCCACTGGG
  TTTGGTGCTGCAATCAATACTGCCAAGGTGACTCCAGGTTCTACCTGTGCTGTGTTTGGC
  CTGGGAGGAGTCGGCTTGTCTGTTGTCATGGGTTGTAAAGCAGCAGGAGCAGCCAGGATC
  ATTGGAGTGGATGTCAACAAGGAGAAATTTAAGAAGGCACAGGAATTGGGTGCTACTGAG
  TGCCTCAACCCTCAGGACTTAAAGAAACCCATTCAAGAAGTTTTATTTGATATGACAGAT
  GCTGGTATAGACTTCTGCTTTGAGGCCATTGGAAATCTGGACGTTCTGGCAGCTGCCCTC
  GCCTCCTGCAATGAGAGCTATGGGGTCTGTGTGGTTGTTGGGGTGTTGCCTGCCAGTGTT
  CAACTCAAAATCAGTGGCCAGTTGTTCTTCTCAGGACGTTCTTTGAAGGGTTCTGTTTTT
  GGAGGCTGGAAGAGCAGACAGCACATCCCTAAACTGGTTGCTGATTATATGGCAGAGAAG
  TTGAATCTAGATCCACTAATTACTCATACTCTGAATCTTGATAAAATCAATGAAGCAGTT
  GAATTAATGAAAACTGGAAAATGTATCCGCTGTATCCTGTTACTTTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000672 unedited
  NGGGTCAGAATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACGAGGTACCTTT
  GTACTTTCTACAGTGAAAGTTGCTACAGGATCTCCCTTTCTCAATAAATTCATCTGCGGT
  GGAGAAAATCAGCATGAGTACTACAGGCCAAGTCATCAGATGCAAAGCAGCCATACTCTG
  GAAGCCTGGTGCACCATTTTCTATTGAAGAGGTAGAAGTGGCCCCACCAAAGGCAAAGGA
  AGTTCGCATAAAGGTTGTGGCCACCGGACTGTGTGGTACAGAGATGAAAGTGTTGGGGAG
  TAAACACTTGGACCTCTTGTATCCCACCATCTTGGGCCATGAAGGGGCTGGAATCGTTGA
  GAGTATTGGAGAAGGAGTAAGCACAGTGAAACCAGGTGACAAAGTTATCACACTCTTTCT
  GCCACAGTGTGGAGAATGTACCTCTTGCCTGAATTCTGAGGGCAATTTTTGTATACAATT
  CAAACAGTCAAAAACCCAACTGATGTCTGATGGTACCAGCAGGTTTACCTGCAAGGGAAA
  ATCAATATATCACTTTGGTAATACCAGCACCTTCTGTGAATACACAGTGATAAAGGAAAT
  CTCAGTTGCCAAGATTGATGCAGTCGCTCCTCTAGAGAAAGTATGCCTAATTAGCTGTGG
  CTTTTCCACTGGGNTTGGTGCTGCAATCAATACTGCCAAGGTGACTCCAGGTTCTACCTG
  TGCTGTGTTTGGCCTGGGAAGGAGTCGCTTGTCTGTTGTCATGGGGTGTAAAGCAGCAGG
  AGCAGCCAGAATCATTGGAGTGGATGTCAACANGGAGAAATTTAAGAAGGCACAGAATGG
  GTGCTACTGAGTGCCTCACCCTTCAGACTTAAGAAACCATNCAGAAGTNTATTTGAATGA
  CAGAGCTGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000672 unedited
  TTCGGTCTTCGGGCTGATGGCAACTTCCCAGTGTCCAGGNGAAAGGCACTGGAGGCAGGG
  GTACACAGGGCATGCCACCCGGGTATCTGTTGCAGGAAAACAGCTATGACCGCGGCCGCA
  ATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGG
  CTTAAGGAACCGAGCTTTATTGGAGCAAAAAGTGTGGACACTGTTTACAACAAAACTTTT
  CCGGGAAAACTTGGATTTCCCAAGACCCGAAAACTCCTCCAAGTTCTCACTGTTAGTAAG
  GTCAATTTGGGGGCAAAACAGGAACATGCCTTAACTGCTGTCAGGAAATAAAAAAACAGA
  GCAGAGTTGGGCATGGAGGCTCCAGCTTAAACTTGGGAAAATGGAAAAAAGCCCTCCCAA
  GTCCAGAGTGAATAGGTTTCATAACACCCATCTCCTCTATTTGAAGGAAGCCGGCCCCTA
  AAGGGAAACACAGGATGCCCAACTTATAAAAATCAAACTGTTATGAGAGTCCTTTGATAT
  CATGTGAAAACCATGATGGGAAAAAAAGACTGAGGGTGCAACCCACCTTCCTGGCCAGTG
  TTAAATCAGGAAACTATTTTGTTTAAATCAAAAAATGATATTCCATTTTTTGGGCTCCCA
  AGGTCATCCAAAGTTTACTGACATGCAGGGACCCCTGTGTGATCTAGTGGGAGTCCAGAG
  CTAGGGGAGTCCAGCTGGAACAAAAGATTCTTCACTAAGAAGGGAACTCTTGTGTGTATG
  AGGGGTTGGAAATAAGGCTCTTTTTTGTTCCAGAGGGAGGGGAAGGAATTCTTTTCCCAA
  GGAGGCGCCTAACCTTTAATCCCAATTCTAGGAAAACTAAAAGGGGCTTGGAGCAAAAAA
  TTCAAAGGGTCCGGGGTTAAAAGATATGGATC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000672
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000672.2, NP_000663.1
• RefSeq Size: 1398 bp
• RefSeq ORF: 1107 bp
• Locus ID: 130
• Cytogenetics: 4q23
• Domains: ADH_zinc_N
• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tyrosine metabolism
• Gene Summary: 'This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) has an alternate 3' sequence including the coding region, as compared to variant 1. The resulting isoform (2) has a distinct and shorter C-terminus, as compared to isoform 1.