BAD (NM_004322) Human Untagged Clone

CAT#: SC107955

BAD (untagged)-Human BCL2-associated agonist of cell death (BAD), transcript variant 1


  "NM_004322" in other vectors (4)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol BAD
Synonyms BBC2; BCL2L8
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_004322 edited
ATGTTCCAGATCCCAGAGTTTGAGCCGAGTGAGCAGGAAGACTCCAGCTCTGCAGAGAGG
GGCCTGGGCCCCAGCCCCGCAGGGGACGGGCCCTCAGGCTCCGGCAAGCATCATCGCCAG
GCCCCAGGCCTCCTGTGGGACGCCAGTCACCAGCAGGAGCAGCCAACCAGCAGCAGCCAT
CATGGAGGCGCTGGGGCTGTGGAGATCCGGAGTCGCCACAGCTCCTACCCCGCGGGGACG
GAGGACGACGAAGGGATGGGGGAGGAGCCCAGCCCCTTTCGGGGCCGCTCGCGCTCGGCG
CCCCCCAACCTCTGGGCAGCACAGCGCTATGGCCGCGAGCTCCGGAGGATGAGTGACGAG
TTTGTGGACTCCTTTAAGAAGGGACTTCCTCGCCCGAAGAGCGCGGGCACAGCAACGCAG
ATGCGGCAAAGCTCCAGCTGGACGCGAGTCTTCCAGTCCTGGTGGGATCGGAACTTGGGC
AGGGGAAGCTCCGCCCCCTCCCAGTGA
>OriGene 5' read for NM_004322 unedited
NTTTCACGATTTGTATACGATTCATATAGGCGGCCGCGNAATTCGCACGAGGGGGAGGCG
GCAGGCCCGGGTCAGGGGCCTCGAGATCGGGCTTGGGCCCAGAGCATGTTCCAGATCCCA
GAGTTTGAGCCGAGTGAGCAGGAAGACTCCAGCTCTGCAGAGAGGGGCCTGGGCCCCAGC
CCCGCAGGGGACGGGCCCTCAGGCTCCGGCAAGCATCATCGCCAGGCCCCAGGCCTCCTG
TGGGACGCCAGTCACCAGCAGGAGCAGCCAACCAGCAGCAGCCATCATGGAGGCGCTGGG
GCTGTGGAGATCCGGAGTCGCCACAGCTCCTACCCCGCGGGGACGGAGGACGACGAAGGG
ATGGGGGAGGAGCCCAGCCCCTTTCGGGGCCGCTCGCGCTCGGCGCCCCCCAACCTCTGG
GCAGCACAGCGCTATGGCCGCGAGCTCCGGAGGATGAGTGACGAGTTTGTGGACTCCTTT
AAGAAGGGACTTCCTCGCCCGAAGAGCGCGGGCACAGCAACGCAGATGCGGCAAAGCTCC
AGCTGGACGCGAGTCTTCCAGTCCTGGTGGGATCGGAACTTGGGCAGGGGAAGCTCCGCC
CCCTCCCAGTGACCTTCGCTCCACATCCCGAAACTCCACCCGTTCCCACTGCCCTGGGCA
GCCATCTTGAATATGGGCGGAAGTACTTCCCTCAGGCCTATGCAAAAAGAGGATCCGTGC
TGTCTCCTTTGGAGGGAGGGCTGACCCAGATTCCCTTCCCGTGCGTGTGAAGCCCCCGGA
AGCTTGGTCCCATCCGAAGTTATGGGTTTTCCGCCCCCAGCCGCCGGTAGTGGCTCCGTG
GCCCCGCCCTCAGCTTCCGGCTTTCCCCCAGCGCCTGCCCTAATTGCGAGCCAGGTTTAC
CGTTGTGTACCGGGG
>OriGene 3' read for NM_004322 unedited
GCCCTCGATAGTCGAGTTTTTTTTTTTTTTTTTTTTGCACAAACGCGGTCTTTATTAACA
TTTGGTAGTGAGCACGGCCCCCAGGGCATCGCGGGGGCTCGGGTCCCGGTGACGCAACGG
TTAAACCTGGCTCGCGACTTAACGCAGGCGCCTGGGGGAAAGCCCGGAGCCTGAGGGCGG
GGCCACGGAGCCACTTCCGGCGGCTGTGGGCGGAAAACCCAAAACTTCCGATGGGACCAA
GCCTTCCGTGGCTTCACACGCACCGGAAGGGAATCTGGGTCAGCCCTCCCTCCAAAGGAG
ACAGCACGGATCCTCTTTTTGCATAGGCCTGAGGGAAGTACTTCCGCCCATATTCAAGAT
GGCTGCCCAGGGCAGTGGGAACGGGTGGAGTTTCGGGATGTGGAGCGAAGGTCACTGGGA
GGGGGCGGAGCTTCCCCTGCCCAAGTTCCGATCCCACCAGGACTGGAAGACTCGCGTCCA
GCTGGAGCTTTGCCGCATCTGCGTTGCTGTGCCCGCGCTCTTCGGGCGAGGAAGTNCCTT
CTTAAAGGAGTCCACAAACTCGTCACTCATCCTCCGGAGCTCGCGGCCATAGCGCTGTGC
TGCCCANAGTTGGGGGGCGCCNAGCGCGAGCGGCCCCNAAAGGGGCTGGGCTCCTCCCCA
TCCCTTTGTCGTCCTCCGTCCCCGCGGGGTATGAGCTGTGGCGACTTCCGATCTCACAGC
CCCAGCGCCTCATGATGGCTGCTGCTGGNTGGCTGCTCCTGCTGGTGACTGGCGTCCACA
CGAAGCCTGNGGCCCTGCGATGATTCTTGCCGAAACCTGAGGCCCCTGTCCCTGTCGGGC
TGGGGCCCAAGCCCCCTCTTGCAAGCTGAATCTTCTGCTACTCGCTCAACTTTGGGACTG
AACATGTCTGGGCCAACCCGATTTGAGGCCTGAACGGNCTGCCCCTCCCTTTGCAGAATC
GGGCCCCCTTAAGAGTGTTACAAATTGAG
Restriction Sites NotI-NotI     
ACCN NM_004322
Insert Size 1110 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_004322.2, NP_004313.1
RefSeq Size 1127 bp
RefSeq ORF 507 bp
Locus ID 572
Cytogenetics 11q13.1
Protein Families Druggable Genome
Protein Pathways Acute myeloid leukemia, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Insulin signaling pathway, Melanoma, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, VEGF signaling pathway
Gene Summary 'The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Dec 2019]'
Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.