HSP90AB1 (NM_007355) Human Untagged Clone

CAT#: SC108085

HSP90AB1 (untagged)-Human heat shock protein 90kDa alpha (cytosolic), class B member 1 (HSP90AB1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HSP90AB1
• Synonyms: D6S182; HSP84; HSP90B; HSPC2; HSPCB
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_007355 edited
  ATGCCTGAGGAAGTGCACCATGGAGAGGAGGAGGTGGAGACTTTTGCCTTTCAGGCAGAA
  ATTGCCCAACTCATGTCCCTCATCATCAATACCTTCTATTCCAACAAGGAGATTTTCCTT
  CGGGAGTTGATCTCTAATGCTTCTGATGCCTTGGACAAGATTCGCTATGAGAGCCTGACA
  GACCCTTCGAAGTTGGACAGTGGTAAAGAGCTGAAAATTGACATCATCCCCAACCCTCAG
  GAACGTACCCTGACTTTGGTAGACACAGGCATTGGCATGACCAAAGCTGATCTCATAAAT
  AATTTGGGAACCATTGCCAAGTCTGGTACTAAAGCATTCATGGAGGCTCTTCAGGCTGGT
  GCAGACATCTCCATGATTGGGCAGTTTGGTGTTGGCTTTTATTCTGCCTACTTGGTGGCA
  GAGAAAGTGGTTGTGATCACAAAGCACAACGATGATGAACAGTATGCTTGGGAGTCTTCT
  GCTGGAGGTTCCTTCACTGTGCGTGCTGACCATGGTGAGCCCATTGGCAGGGGTACCAAA
  GTGATCCTCCATCTTAAAGAAGATCAGACAGAGTACCTAGAAGAGAGGCGGGTCAAAGAA
  GTAGTGAAGAAGCATTCTCAGTTCATAGGCTATCCCATCACCCTTTATTTGGAGAAGGAA
  CGAGAGAAGGAAATTAGTGATGATGAGGCAGAGGAAGAGAAAGGTGAGAAAGAAGAGGAA
  GATAAAGATGATGAAGAAAAGCCCAAGATCGAAGATGTGGGTTCAGATGAGGAGGATGAC
  AGCGGTAAGGATAAGAAGAAGAAAACTAAGAAGATCAAAGAGAAATACATTGATCAGGAA
  GAACTAAACAAGACCAAGCCTATTTGGACCAGAAACCCTGATGACATCACCCAAGAGGAG
  TATGGAGAATTCTACAAGAGCCTCACTAATGACTGGGAAGACCACTTGGCAGTCAAGCAC
  TTTTCTGTAGAAGGTCAGTTGGAATTCAGGGCATTGCTATTTATTCCTCGTCGGGCTCCC
  TTTGACCTTTTTGAGAACAAGAAGAAAAAGAACAACATCAAACTCTATGTCCGCCGTGTG
  TTCATCATGGACAGCTGTGATGAGTTGATACCAGAGTATCTCAATTTTATCCGTGGTGTG
  GTTGACTCTGAGGATCTGCCCCTGAACATCTCCCGAGAAATGCTCCAGCAGAGCAAAATC
  TTGAAAGTCATTCGCAAAAACATTGTTAAGAAGTGCCTTGAGCTCTTCTCTGAGCTGGCA
  GAAGACAAGGAGAATTACAAGAAATTCTATGAGGCATTCTCTAAAAATCTCAAGCTTGGA
  ATCCACGAAGACTCCACTAACCGCCGCCGCCTGTCTGAGCTGCTGCGCTATCATACCTCC
  CAGTCTGGAGATGAGATGACATCTCTGTCAGAGTATGTTTCTCGCATGAAGGAGACACAG
  AAGTCCATCTATTACATCACTGGTGAGAGCAAAGAGCAGGTGGCCAACTCAGCTTTTGTG
  GAGCGAGTGCGGAAACGGGGCTTCGAGGTGGTATATATGACCGAGCCCATTGACGAGTAC
  TGTGTGCAGCAGCTCAAGGAATTTGATGGGAAGAGCCTGGTCTCAGTTACCAAGGAGGGT
  CTGGAGCTGCCTGAGGATGAGGAGGAGAAGAAGAAGATGGAAGAGAGCAAGGCAAAGTTT
  GAGAACCTCTGCAAGCTCATGAAAGAAATCTTAGATAAGAAGGTTGAGAAGGTGACAATC
  TCCAATAGACTTGTGTCTTCACCTTGCTGCATTGTGACCAGCACCTACGGCTGGACAGCC
  AATATGGAGCGGATCATGAAAGCCCAGGCACTTCGGGACAACTCCACCATGGGCTATATG
  ATGGCCAAAAAGCACCTGGAGATCAACCCTGACCACCCCATTGTGGAGACGCTGCGGCAG
  AAGGCTGAGGCCGACAAGAATGATAAGGCAGTTAAGGACCTGGTGGTGCTGCTGTTTGAA
  ACCGCCCTGCTATCTTCTGGCTTTTCCCTTGAGGATCCCCAGACCCACTCCAACCGCATC
  TATCGCATGATCAAGCTAGGTCTAGGTATTGATGAAGATGAAGTGGCAGCAGAGGAACCC
  AATGCTGCAGTTCCTGATGAGATCCCCCCTCTCGAGGGCGATGAGGATGCGTCTCGCATG
  GAAGAAGTCGATTAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007355 unedited
  CCCCCATTCCCACGAGGCCGGCGCATTGTTGGGACTGTCTGGGTATCGGAAAGCAATCCT
  ACGTTGCTCACTATTACGTATAATCCTTTTCTTTTCAAGATGCCTGAGGAAGTGCACCAT
  GGAGAGGAGGAGGTGGAGACTTTTGCCTTTCATGCAGAAATTGCCCAACTCATGTCCCTC
  ATCATCAATACCTTCTATTCCAACAAGGAGATTTTCCTTCGGGAGTTGATCTCTAATGCT
  TCTGATGCCTTGGACAAGATTCGCTATGAGAGCCTGACAGACCCTTCGAAGTTGGACAGT
  GGTAAAGAGCTGAAAATTGACATCATCCCCAACCCTCATGAACGTACCCTGACTTTGGTA
  GACACAGGCATTGGCATGACCAAAGCTGATCTCATAAATAATTTGGGAACCATTGCCAAG
  TCTGGTACTAAAGCATTCATGGAGGCTCTTCATGCTGGTGCAGACATCTCCATGATTGGG
  CAGTTTGGTGTTGGCTTTTATTCTGCCTACTTGGTGGCAGAGAAAGTGGTTGTGATCACA
  AAGCACAACGATGATGAACAGTATGCTTGGGAGTCTTCTGCTGGAAGTTCCTTCACTGTG
  CGTGCTGACCATGGTGAGCCCATTGGCAGGGGTACCAAAGTGATCCTCCATCTTAAAGAA
  GATCAGACAGAGTACCTAGAATAGAGGCGGGTCAAAGAAGTAGTGAAGAAGCATTCTCAG
  TTCATATGCTATCCCATCACCCTTTATTTGGAGAATGAACGAGAGAATGAATTATTGATG
  ATGATGCAGAGGAAGAAATAGTGATGAAGAAGAGGAGATAAGATGATGAAGGATAGCCAA
  GATCGCAGATGTTGGTTCAGATGATGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_007355 unedited
  CCCCCCCCCCANNNNNCCCNNCCCCNACACCACTTCTTGACTTGCCCCGCGGNCCGCAAT
  CTAGGAATCGGGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGATAA
  AAACGGGATATTCTTTATTTTGCATACTTTAATTTCAGAACAAAATGAAGAAAATAAAAT
  AAACCCCAATACACAACATTCAATCCTGGTGTCAAAAATAAAAAGGGAATGGGGCTTGAC
  ACCCTTAATTTACTGGCTTTAACACAAGGACAGGAGAGGGAAAAAAACACTAAACACCAC
  CAGGGGGAGCCAGGGGGGACAGGGGCACTCCAGGCTGCAGTGGGAGCCCATGGGGACACT
  ATACAAGGGCACAAGTTTTCCAACTATGAACTCCTAACCTAATCGACTTCTTTCATGCGA
  GAAGCATCCTTATCGCCCTTGAGAGGGGGGATCTCATCAGGAACTGGAGCATTGGGTTCC
  TCTGGTGGCACTTTATTTTCATCAATACCTAAACCTAACTTGATCATGCCATAAATGCGG
  GTGGAGTGGGTCTGGGGATCCTCAAGGGAAAAGCCAGAAGATAGCAGGGCGGTTTTAAAC
  AGCAGCACCACCAGGGCCTTAACTGGCTTATCATTCTTGGCGGGCTCAACCTTCTGCCGC
  AGCGGTTTCACAATGGGGTGGTCAGGGTTGATCTCCAGGTGCTTTTTGCCATCATATAGC
  CCCAGGTGGAGTTGTCCCCGAGTGCCCTGGCTTTCATGATCCGCTCCATAATGGCTGGCC
  AGCCGTAAGTGCTGGGGCACAAAGCAACAAGGTGAAAAACCACAGTCTATTGGGAGATTG
  CCACCTTTTCAACCTTTCTATATAAAAATTCTTTCATTGAGCCTGCAAAGGGTCTAAAAA
  CTTTGCCTGGCTCTCTTTCCAATTTTTTTTTTTCCCCCTCAACCTCAGGCAAGTTCAAAC
  CCTTCTTGTGTACTGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_007355
• Insert Size: 2640 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_007355.2, NP_031381.2
• RefSeq Size: 2567 bp
• RefSeq ORF: 2175 bp
• Locus ID: 3326
• Cytogenetics: 6p21.1
• Domains: HSP90, HATPase_c
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Antigen processing and presentation, NOD-like receptor signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer
• Gene Summary: 'This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Dec 2012]'
  Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein (isoform a).